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The GR-ANXA1 pathway is a pathological player and a candidate target in epilepsy

Emma Zub , Geoffrey Canet , Rita Garbelli , Marine Blaquière , Laura Rossini , et al.
FASEB Journal, In press, pp.fj.201901596R. ⟨10.1096/fj.201901596R⟩
Article dans une revue hal-02350122v1
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Superiority of the Triple-Acting 5-HT 6 R/5-HT 3 R Antagonist and MAO-B Reversible Inhibitor PZ-1922 over 5-HT 6 R Antagonist Intepirdine in Alleviation of Cognitive Deficits in Rats

Katarzyna Grychowska , Uriel López-Sánchez , Mathieu Vitalis , Geoffrey Canet , Grzegorz Satała , et al.
Journal of Medicinal Chemistry, 2023, 66 (21), pp.14928-14947. ⟨10.1021/acs.jmedchem.3c01482⟩
Article dans une revue hal-04235140v1
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Alzheimer's Disease Related Markers, Cellular Toxicity and Behavioral Deficits Induced Six Weeks after Oligomeric Amyloid-β Peptide Injection in Rats

Charleine Zussy , Anthony Brureau , Emeline Keller , Stéphane Marchal , Claire Blayo , et al.
PLoS ONE, 2013, 8 (1), ⟨10.1371/journal.pone.0053117⟩
Article dans une revue hal-01923527v1

[The corticotropic axis response after subcutaneous endotoxin injection is not associated with the increase of plasma interleukin-1 beta].

Laurent Givalois , G Givalois , M Mekaouche , F Malaval , G Gaillet , et al.
Comptes rendus des séances de la Société de biologie et de ses filiales, 1995, pp.323-31
Article dans une revue hal-01923642v1
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Chronic Glucocorticoids Consumption Triggers and Worsens Experimental Alzheimer’s Disease-Like Pathology by Detrimental Immune Modulations

Geoffrey Canet , Charleine Zussy , Célia Hernandez , Nathalie Chevallier , Nicola Marchi , et al.
Neuroendocrinology, 2021, 112 (10), pp.982 - 997. ⟨10.1159/000521559⟩
Article dans une revue hal-03870294v1

Role of Glucocorticoids in the Modulation of Corticotropin-Releasing Hormone mRNA Level by the Endogenous Benzodiazepine Receptor Ligand Octadecaneuropeptide in Rat Brain

G Givalois , Songyun Li , Georges Pelletier , Laurent Givalois
Neuroendocrinology, 1998, 68 (2), pp.98 - 104. ⟨10.1159/000054355⟩
Article dans une revue hal-01923614v1

Concomitant changes in CRH mRNA levels in rat hippocampus and hypothalamus following immobilization stress.

Laurent Givalois , S Arancibia , L Tapia-Arancibia
Molecular Brain Research, 2000, pp.166-71. ⟨10.1016/s0169-328x(99)00290-9⟩
Article dans une revue istex hal-01923606v1

Blockade of Tau Hyperphosphorylation and Aβ1–42 Generation by the Aminotetrahydrofuran Derivative ANAVEX2-73, a Mixed Muscarinic and σ1 Receptor Agonist, in a Nontransgenic Mouse Model of Alzheimer’s Disease

Valentine Lahmy , Johann Meunier , Susanna Malmstrom , Gaëlle Naert , Laurent Givalois , et al.
Neuropsychopharmacology, 2013, 38 (9), pp.1706 - 1723. ⟨10.1038/npp.2013.70⟩
Article dans une revue hal-01923523v1

Effects of pharmacological lesion of adrenergic innervation of the dorsal vagal nucleus on pancreatic insulin secretion in normal and vagotomized rats.

Laurent Givalois , M Siaud , M Mekaouche , G Givalois , M Balmefrezol , et al.
Physiological Research, 1995, pp.227-31
Article dans une revue hal-01923641v1

Temporal cascade of plasma level surges in ACTH, corticosterone, and cytokines in endotoxin-challenged rats

G Givalois , J. Dornand , M. Mekaouche , M. Solier , A. Bristow , et al.
AJP - Regulatory, Integrative and Comparative Physiology, 1994, 267 (1), pp.R164 - R170. ⟨10.1152/ajpregu.1994.267.1.R164⟩
Article dans une revue hal-01923650v1

Involvement of Endogenous Brain-Derived Neurotrophic Factor in Hypothalamic-Pituitary-Adrenal Axis Activity

G. Naert , C. Zussy , C. Tran van Ba , N. Chevallier , Y.-P. Tang , et al.
Journal of Neuroendocrinology, 2015, 27 (11), pp.850 - 860. ⟨10.1111/jne.12324⟩
Article dans une revue istex hal-01923508v1

Acute stress and dexamethasone rapidly increase hippocampal somatostatin synthesis and release from the dentate gyrus hilus

L Arancibia , Olivier Payet , Laurent Givalois , Lucia Tapia-Arancibia , Sandor Arancibia
Hippocampus, 2001, 11 (4), pp.469 - 477. ⟨10.1002/hipo.1061⟩
Article dans une revue istex hal-01923563v1

Continuous i.c.v. infusion of brain-derived neurotrophic factor modifies hypothalamic–pituitary–adrenal axis activity, locomotor activity and body temperature rhythms in adult male rats

L Naert , G. Ixart , L. Tapia-Arancibia , Laurent Givalois , G. Naert
Neuroscience, 2006, 139 (2), pp.779 - 789. ⟨10.1016/j.neuroscience.2005.12.028⟩
Article dans une revue istex hal-01923551v1

Deregulation of hypothalamic-pituitary-adrenal axis functions in an Alzheimer's disease rat model

Anthony Brureau , Charleine Zussy , Brice Delair , Charline Ogier , Guy Ixart , et al.
Neurobiology of Aging, 2013, 34 (5), pp.1426 - 1439. ⟨10.1016/j.neurobiolaging.2012.11.015⟩
Article dans une revue hal-01923530v1

Dehydroepiandrosterone administration reverses the inhibitory influence of aging on gonadotrophin-releasing hormone gene expression in the male and female rat brain

G. Li , G Givalois , Georges Pelletier , Songyun Li , Laurent Givalois
Endocrine, 1997, 6 (3), pp.265 - 270. ⟨10.1007/BF02820502⟩
Article dans une revue istex hal-01923621v1

Involvement of neurosteroids in the effect of the endogenous benzodiazepine receptor ligand octadecaneuropeptide (ODN) on gonadotropin-releasing hormone gene expression in rat brain.

Laurent Givalois , G. Li , G. Pelletier
Journal of Neuroendocrinology, 1997, pp.229-33. ⟨10.1046/j.1365-2826.1997.00574.x⟩
Article dans une revue istex hal-01923624v1
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Leucettine L41, a DYRK1A-preferential DYRKs/CLKs inhibitor, prevents memory impairments and neurotoxicity induced by oligomeric Aβ25-35 peptide administration in mice.

Gaëlle Naert , Valentine Ferré , Johann Meunier , Emeline Keller , Susanna Malmstrom , et al.
European Neuropsychopharmacology, 2015, 25 (11), pp.2170-2182. ⟨10.1016/j.euroneuro.2015.03.018⟩
Article dans une revue hal-01146496v1
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Altered Memory Capacities and Response to Stress in p300/CBP-Associated Factor (PCAF) Histone Acetylase Knockout Mice

Tangui Maurice , Florian Duclot , Johann Meunier , Gaëlle Naert , Laurent Givalois , et al.
Neuropsychopharmacology, 2008, 33 (7), pp.1584-1602. ⟨10.1038/sj.npp.1301551⟩
Article dans une revue inserm-00218215v1

A single brain-derived neurotrophic factor injection modifies hypothalamo–pituitary–adrenocortical axis activity in adult male rats

Laurent Givalois , Gaëlle Naert , Florence Rage , Guy Ixart , Sandor Arancibia , et al.
Molecular and Cellular Neuroscience, 2004, 27 (3), pp.280 - 295. ⟨10.1016/j.mcn.2004.07.002⟩
Article dans une revue istex hal-01923553v1
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Overview of alkyl quercetin lipophenol synthesis and its protective effect against carbonyl stress involved in neurodegeneration

Léa Otaegui , Jordan Lehoux , Leo Martin , Laurent Givalois , Thierry Durand , et al.
Organic & Biomolecular Chemistry, In press, ⟨10.1039/d4ob00066h⟩
Article dans une revue hal-04520041v1

Immobilization stress rapidly modulates BDNF mRNA expression in the hypothalamus of adult male rats.

Florence Rage , Laurent Givalois , F Marmigère , L Arancibia , S Arancibia
Neuroscience, 2002, 112 (2), pp.309-18. ⟨10.1016/S0306-4522(02)00072-6⟩
Article dans une revue istex hal-01923562v1
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Glucocorticoid receptors signaling impairment potentiates amyloid‐β oligomers‐induced pathology in an acute model of Alzheimer’s disease

Geoffrey Canet , Fanny Pineau , Charleine Zussy , Célia Hernandez , Hazel Hunt , et al.
FASEB Journal, 2019, ⟨10.1096/fj.201900723RRR⟩
Article dans une revue hal-02407317v1

Effects of ageing and dehydroepiandrosterone administration on pro-opiomelanocortin mRNA expression in the anterior and intermediate lobes of the rat pituitary.

Laurent Givalois , S. Li , G. Pelletier
Journal of Neuroendocrinology, 1999, pp.737-42. ⟨10.1046/j.1365-2826.1999.00392.x⟩
Article dans une revue istex hal-01923607v1

Superior cervical ganglionectomy suppresses circadian corticotropic rhythms in male rats in the short term (5 days) and long term (10 days).

Laurent Givalois , L Siaud , M Mekaouche , D. Maurel , G Givalois , et al.
Brain Research, 1994, pp.273-8. ⟨10.1016/0006-8993(94)90237-2⟩
Article dans une revue istex hal-01923648v1
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Deletion of plasma Phospholipid Transfer Protein (PLTP) increases microglial phagocytosis and reduces cerebral amyloid-β deposition in the J20 mouse model of Alzheimer's disease

Marine Mansuy , Stella Baille , Geoffrey Canet , Amélie Borie , Catherine Cohen-Solal , et al.
Oncotarget, 2018, 9 (28), pp.19688-19703. ⟨10.18632/oncotarget.24802⟩
Article dans une revue hal-01823805v1

Effects of aging and melatonin administration on gonadotropin-releasing hormones (GnRH) gene expression in the male and female rat.

Laurent Givalois , L Li , G. Pelletier
Peptides, 1997, pp.1023-8. ⟨10.1016/s0196-9781(97)00076-4⟩
Article dans une revue istex hal-01923625v1

Influence of adrenal glands on the modulation of prolactin gene expression by the endogenous benzodiazepine ligand octadecaneuropeptide in the male rat pituitary gland.

Laurent Givalois , G Wang , L Li , G. Pelletier
Journal of Neuroendocrinology, 1998, pp.193-8. ⟨10.1046/j.1365-2826.1998.00189.x⟩
Article dans une revue istex hal-01923616v1

Age-related decrease in the hypothalamic CRH mRNA expression is reduced by dehydroepiandrosterone (DHEA) treatment in male and female rats.

Laurent Givalois , S. Li , G. Pelletier
Molecular Brain Research, 1997, pp.107-14. ⟨10.1016/s0169-328x(97)00088-0⟩
Article dans une revue istex hal-01923620v1

Immobilization Stress Rapidly and Differentially Modulates BDNF and TrkB mRNA Expression in the Pituitary Gland of Adult Male Rats

Laurent Givalois , Frédéric Marmigère , Florence Rage , Guy Ixart , Sandor Arancibia , et al.
Neuroendocrinology, 2001, 74 (3), pp.148 - 159. ⟨10.1159/000054681⟩
Article dans une revue hal-01923587v1

The octadecaneuropeptide-induced response of corticotropin-releasing hormone messenger RNA levels is mediated by GABA(A) receptors and modulated by endogenous steroids.

Laurent Givalois , G Grinevich , S. Li , G Garcia-De-Yebenes , G. Pelletier
Neuroscience, 1998, pp.557-67. ⟨10.1016/s0306-4522(97)00650-7⟩
Article dans une revue istex hal-01923615v1