Sihem Dali Youcef, Mansour Dolé Kerim, Hocine Ilitki, Laurent El Kaim. A Passerini/Tsuji-Trost access to dienamide derivatives. Tetrahedron Letters, Elsevier, 2019, 60 (2), pp.102-105. ⟨10.1016/j.tetlet.2018.11.068⟩. ⟨hal-02096732⟩

Cristina Cheibas, Marie Cordier, Yanyan Li, Laurent El Kaim. A Ugi Straightforward Access to Bis-β-lactam Derivatives. European Journal of Organic Chemistry, Wiley-VCH Verlag, 2019, 2019 (27), pp.4457-4463. ⟨10.1002/ejoc.201900678⟩. ⟨hal-02280748⟩

Alaa Zidan, Abeer El-Naggar, Nour Abd El-Sattar, Ali Khalil Ali, Laurent El Kaim. Raising the Diversity of Ugi Reactions Through Selective Alkylations and Allylations of Ugi Adducts. Frontiers in Chemistry, Frontiers Media, 2019, 7 (20), ⟨10.3389/fchem.2019.00020⟩. ⟨hal-02096847⟩

Alaa Zidan, Marie Cordier, Abeer El-Naggar, Nour Abd El-Sattar, Mohamed Ali Hassan, et al.. Propargylation of Ugi Amide Dianion: An Entry into Pyrrolidinone and Benzoindolizidine Alkaloid Analogues. Organic Letters, American Chemical Society, 2018, 20 (9), pp.2568-2571. ⟨10.1021/acs.orglett.8b00687⟩. ⟨hal-02094200⟩

Shuanglong Jia, Laurent El Kaim. A Passerini/Michael Pathway towards Butyrolactones. European Journal of Organic Chemistry, Wiley-VCH Verlag, 2018, 2018 (46), pp.6457-6464. ⟨10.1002/ejoc.201800958⟩. ⟨hal-02095101⟩

Mansour Dolé Kerim, Shuanglong Jia, Chrysoula Theodorakidou, Sébastien Prevost, Laurent El Kaim. Palladium triggered diene formation from nitro allylic compounds: a versatile entry into naphthalene derivatives. Chemical Communications, Royal Society of Chemistry, 2018, 54 (77), pp.10917-10920. ⟨10.1039/c8cc06536e⟩. ⟨hal-02094211⟩

Mansour Dolé Kerim, Martin Cattoen, Nicolas Fincias, Aurélie Dos santos, Stellios Arseniyadis, et al.. Palladium-catalysed O -Allylation of α-Hydroxyphosphonates: An Expedient Entry into Phosphono-oxaheterocycles. Advanced Synthesis and Catalysis, Wiley-VCH Verlag, 2018, 360 (3), pp.449-454. ⟨10.1002/adsc.201701150⟩. ⟨hal-02091718⟩

Samira Baaziz, Mansour Kerim, Marie Cordier, Lamouri Hammal, Laurent El Kaim. Metal-free Deamidative Ugi Access to Isoindolinones. SYNLETT, Georg Thieme Verlag, 2018, 29 (14), pp.1842-1846. ⟨10.1055/s-0037-1610189⟩. ⟨hal-01999460⟩

Shuanglong Jia, Laurent El Kaim. Mannich reaction of trifluoroacetaldehyde hydrazones: a useful entry to trifluoromethyl substituted heterocycles. Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2018, 16 (9), pp.1457-1460. ⟨10.1039/c7ob02840g⟩. ⟨hal-02095052⟩

Sudipta Ponra, Aude Nyadanu, Sylvie Maurin, Laurent El Kaim, Laurence Grimaud, et al.. TiCl4-Mediated Synthesis of 3,4-Hetero-Disubstituted Isocoumarins by Means of Isocyanide Insertion Reactions. SYNTHESIS, Georg Thieme Verlag, 2018, 50 (06), pp.1331-1342. ⟨10.1055/s-0036-1591733⟩. ⟨hal-02095068⟩

Madjid Ait Sidhoum, Laurent El Kaim, Laurence Grimaud. 4-Aminopyrimidine libraries from the Ugi-Smiles reaction of thiouracil. Tetrahedron, Elsevier, 2018, 74 (38), pp.5222-5231. ⟨10.1016/j.tet.2018.04.058⟩. ⟨hal-02096394⟩

Luca Alessandro Perego, Simon Wagschal, Raymond Grüber, Paul Fleurat-Lessard, Laurent El Kaim, et al.. From Benzofurans to Indoles: Palladium-Catalyzed Reductive Ring-Opening and Closure via β-Phenoxide Elimination. Advanced Synthesis and Catalysis, Wiley-VCH Verlag, 2018, 361 (1), pp.151-159. ⟨10.1002/adsc.201801225⟩. ⟨hal-01913160⟩

Laurent El Kaim, Aurélie dos Santos, Marie Cordier, Alaa Zidan, Julian Garrec, et al.. β-Lactam Synthesis through Diodomethane Addition to Amide Dianions. Angewandte Chemie International Edition, Wiley-VCH Verlag, 2017, 56 (40), pp.12179 - 12183. ⟨10.1002/anie.201706315⟩. ⟨hal-01664662⟩

Noisette Narboni, Laurent El Kaim. Passerini/Tsuji-Trost Strategy towards Pyrrole Derivatives. European Journal of Organic Chemistry, Wiley-VCH Verlag, 2017, 2017 (29), pp.4242-4246. ⟨10.1002/ejoc.201700653⟩. ⟨hal-02094146⟩

Somayeh Ghorbani, Ebrahim Soleimani, Laurent El Kaim. Nef-Perkow cascade towards imidazo phosphate derivatives. Tetrahedron Letters, Elsevier, 2017, 58 (49), pp.4595-4597. ⟨10.1016/j.tetlet.2017.10.055⟩. ⟨hal-02096435⟩

Laurent El Kaim, Abdelbari Abdessalem, Raoudha Abderrahim, Aurélie dos Santos, Laurence Grimaud. Ugi–Smiles Couplings of Purine Derivatives. SYNLETT, Georg Thieme Verlag, 2017, 28 (06), pp.691 - 694. ⟨10.1055/s-0036-1588117⟩. ⟨hal-01664666⟩

Laurent El Kaim, Aurélie dos Santos, Marie Cordier. Nef–Perkow–Mumm Cascade towards Imido Phosphate Derivatives. SYNLETT, Georg Thieme Verlag, 2017, 28 (19), pp.2637 - 2641. ⟨10.1055/s-0036-1590856⟩. ⟨hal-01664663⟩

Valentina Mercalli, Aude Nyadanu, Marie Cordier, Gian Cesare Tron, Laurence Grimaud, et al.. N–N bond formation in Ugi processes: from nitric acid to libraries of nitramines. Chemical Communications, Royal Society of Chemistry, 2017, 53 (13), pp.2118 - 2121. ⟨10.1039/C6CC10288C⟩. ⟨hal-01472845⟩

Laurent El Kaim, El El Mamouni, Aurélie dos Santos, Hocine Ilitki. Passerini/Friedel–Crafts Route towards Indole Derivatives. SYNLETT, Georg Thieme Verlag, 2016, 27 (18), pp.2571 - 2574. ⟨10.1055/s-0035-1561497⟩. ⟨hal-01664674⟩

Mansour Kerim, Laurent El Kaim. Piperazine as Leaving Group in A3 Adducts: Fast Access to Alkynyl Indoles. SYNLETT, Georg Thieme Verlag, 2016, 27 (10), pp.1572-1576 ⟨10.1055/s-0035-1561396⟩. ⟨hal-01444342⟩

Luca A. Perego, Paul Fleurat-Lessard, Laurent El Kaim, Ilaria Ciofini, Laurence Grimaud. Multiple Roles of Isocyanides in Palladium-Catalyzed Imidoylative Couplings: A Mechanistic Study. Chemistry - A European Journal, Wiley-VCH Verlag, 2016, 22 (43), pp.15491 - 15500. ⟨10.1002/chem.201602913⟩. ⟨hal-01400558⟩

Sudipta Ponra,, Aude Nyadanu,, Laurent El Kaim, Laurence Grimaud, Maxime R. Vitale. TiCl4-Mediated Preparation of Thiophthalide Derivatives via Formal Thio-Passerini Reactions. Organic Letters, American Chemical Society, 2016, 18 (16), pp.4060-4063. ⟨10.1021/acs.orglett.6b01937⟩. ⟨hal-01456154⟩

Elhachemia Elmamouni, M. Cattoen, Marie Cordier, Janine Cossy, Stellios Arseniyadis, et al.. Selective Tsuji-Trost type C-allylation of hydrazones: a straightforward entry into 4,5-dihydropyrazoles. Chemical Communications, Royal Society of Chemistry, 2016, 52 (100), pp.14490-14493 ⟨10.1039/c6cc08171a⟩. ⟨hal-01623194⟩

Elodie Martinand-Lurin, Aurélie dos Santos, Emmanuelle Robineau, Pascal Retailleau, Philippe Dauban, et al.. Optimized Conditions for Passerini-Smiles Reactions and Applications to Benzoxazinone Syntheses. Molecules, MDPI, 2016, 21 (9), pp.1257. ⟨10.3390/molecules21091257⟩. ⟨hal-01373389⟩

Marie Cordier, Aurélie dos Santos, Laurent El Kaim, Noisette Narboni. Passerini/Tsuji-Trost strategies towards achieving lactams and cyclopentane derivatives.. Chemical Communications, Royal Society of Chemistry, 2015, 51 (29), pp.6411-4. ⟨10.1039/C5CC00584A⟩. ⟨hal-01152233⟩

Abdelbari Ben Abdessalem, Raoudha Abderrahim, Asma Agrebie, Aurélie dos Santos, Laurent El Kaim, et al.. Correction: Formal [3+2] cycloaddition of Ugi adducts towards pyrrolines. Chemical Communications, Royal Society of Chemistry, 2015, 51 (97), ⟨10.1039/c5cc90512e⟩. ⟨hal-01276153⟩

Monia Aouali, Dhekra Mhalla, Fatma Allouche, Laurent El Kaim, Slim Tounsi, et al.. Synthesis, antimicrobial and antioxidant activities of imidazotriazoles and new multicomponent reaction toward 5-amino-1-phenyl[1,2,4]triazole derivatives. Medicinal Chemistry Research, Springer Verlag, 2015, 24 (6), pp.2732-2741. ⟨10.1007/s00044-015-1322-z⟩. ⟨hal-01186609⟩

Abdelbari Ben Abdessalem, Raoudha Abderrahim, Laurent El Kaim. A Nonoxidative Passerini Pathway to α-Ketoamides. SYNLETT, Georg Thieme Verlag, 2015, 26 (18), pp.2537-2540. ⟨10.1055/s-0035-1560632⟩. ⟨hal-01245816⟩

Nancy Alvarez-Rodríguez, Aurélie dos Santos, Laurent El Kaim, Rocío Gámez-Montaño. The Ugi Reaction of Cyanoacetic Acid as a Route to Tetramic Acid Derivatives. SYNLETT, Georg Thieme Verlag, 2015, 26 (16), ⟨10.1055/s-0035-1560050⟩. ⟨hal-01217812⟩

Naïm Ait Sidhoum, Aurélie dos Santos, Laurent El Kaim, Laetitia Legras. Pyrrolidinone and Piperidinone Isocyanides from Isocyano Esters. European Journal of Organic Chemistry, Wiley-VCH Verlag, 2014, 2014 (23), pp.4949-4952. ⟨10.1002/ejoc.201402572⟩. ⟨hal-01065722⟩

Abdelbari Ben Abdessalem, Raoudha Abderrahim, Asma Agrebie, Aurélie dos Santos, Laurent El Kaim, et al.. Formal [3+2] cycloaddition of Ugi adducts towards pyrrolines. Chemical Communications, Royal Society of Chemistry, 2014, 51 (6), pp.1116-1119. ⟨10.1039/C4CC08282F⟩. ⟨hal-01114416⟩

Laurent El Kaim, Laurence Grimaud. The Ugi-Smiles and Passerini-Smiles Couplings: A Story About Phenols in Isocyanide-Based Multicomponent Reactions. European Journal of Inorganic Chemistry, Wiley-VCH Verlag, 2014, 2014 (35), ⟨10.1002/ejoc.201402783⟩. ⟨hal-01217971⟩

Fabio La Spisa, Gian Cesare Tron, Laurent El Kaim. The Nef Reaction of Isocyanides. SYNTHESIS, Georg Thieme Verlag, 2014, 46 (7), pp.829-841. ⟨10.1055/s-0033-1338596⟩. ⟨hal-01015399⟩

Aurélie dos Santos, Laurent El Kaim. Reductive Passerini/Tsuji-Trost Strategy towards beta,gamma-Unsaturated Amides. SYNLETT, Georg Thieme Verlag, 2014, 25 (13), pp.1901-1903. ⟨10.1055/s-0033-1340187⟩. ⟨hal-01065732⟩

Damien Cartigny, Aurélie dos Santos, Laurent El Kaim, Laurence Grimaud, Roland Jacquot, et al.. Nitrile Synthesis through Catalyzed Cascades Involving Acid-Nitrile Exchange. SYNTHESIS, Georg Thieme Verlag, 2014, 46 (13), pp.1802-1806. ⟨10.1055/s-0033-1341227⟩. ⟨hal-01044733⟩

Christian Amatore, Laurent El Kaim, Laurence Grimaud, Anny Jutand, Alice Meignié, et al.. Kinetic Data on the Synergetic Role of Amines and Water in the Reduction of Phosphine-Ligated Palladium(II) to Palladium(0). European Journal of Organic Chemistry, Wiley-VCH Verlag, 2014, 22 (august), pp.4709-4713. ⟨10.1002/ejoc.201402519⟩. ⟨hal-01057787⟩

Romain Ramozzi, Nicolas Chéron, Laurent El Kaim, Laurence Grimaud, Paul Fleurat-Lessard. Predicting New Ugi-Smiles Couplings: A Combined Experimental and Theoretical Study. Chemistry - A European Journal, Wiley-VCH Verlag, 2014, 20 (29), pp.9094-9099. ⟨10.1002/chem.201400336⟩. ⟨hal-01057795⟩

E. Martinand-Lurin, A. dos Santos, Laurent El Kaim, L. Grimaud, P. Retailleau. Double Smiles rearrangement of Passerini adducts towards benzoxazinones.. Chemical Communications, Royal Society of Chemistry, 2014, 50 (17), pp.2214-7. ⟨10.1039/c3cc49022j⟩. ⟨hal-00958815⟩

E. Martinand-Lurin, Laurent El Kaim, L. Grimaud. Benzoxazinone synthesis via Passerini-Smiles couplings. Tetrahedron Letters, Elsevier, 2014, 55 (37), pp.5144-5146. ⟨10.1016/j.tetlet.2014.07.088⟩. ⟨hal-01075102⟩

Laurent El Kaim, Unnamatla Basavanag, Aurélie Dos santos, Rocio Gámez-Montaño, Laurence Grimaud. Three-Component Metal-Free Arylation of Isocyanides. Angewandte Chemie International Edition, Wiley-VCH Verlag, 2013, 52 (28), pp.7194 - 7197. ⟨10.1002/anie.201302659⟩. ⟨hal-01664717⟩

Laurent El Kaim, Laurence Grimaud, Simon Wagschal. Pyrrolo[2,3-d]pyrimidine synthesis through activation of N-benzyl groups by distal amides. Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2013, 11 (40), ⟨10.1039/C3OB41477A⟩. ⟨hal-01664695⟩

Laurent El Kaim, Laurence Grimaud, Patil Pravin. Lewis Acid Mediated Fragmentation of Tetrazoles towards Triazoles. European Journal of Organic Chemistry, Wiley-VCH Verlag, 2013, 2013 (22), pp.4752 - 4755. ⟨10.1002/ejoc.201300620⟩. ⟨hal-01664716⟩

Asma Agrebi, Fatma Allouche, Fakher Chabchoub, Laurent El Kaim, Sérgio Alves, et al.. Sc(OTf)3 promoted multicomponent synthesis of fluorescent imidazo[1,2-c]pyrazolo[3,4-d]pyrimidine. Tetrahedron Letters, Elsevier, 2013, 54 (35), pp.4781 - 4784. ⟨10.1016/j.tetlet.2013.06.136⟩. ⟨hal-01664696⟩

Laurent El Kaim, Asma Agrebi, Fatma Allouche, Fakher Chabchoub. Cyclization Cascade of Hydrazono Ugi Adducts towards Pyrazoles. European Journal of Organic Chemistry, Wiley-VCH Verlag, 2013, 2013 (26), pp.5805 - 5808. ⟨10.1002/ejoc.201300787⟩. ⟨hal-01664698⟩

Laurent El Kaim, Luis Cárdenas-Galindo, Alejandro Islas-Jácome, Nancy Alvarez-Rodríguez, Rocío Gámez-Montaño. Synthesis of 2-Tetrazolylmethyl-2,3,4,9-tetrahydro-1H-β-carbolines by a One-Pot Ugi-Azide/Pictet–Spengler Process. SYNTHESIS, Georg Thieme Verlag, 2013, 46 (01), pp.49 - 56. ⟨10.1055/s-0033-1340051⟩. ⟨hal-01664692⟩

Aurelie dos Santos, Laurent El Kaim, Laurence Grimaud. Metal-free aerobic oxidation of benzazole derivatives. Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2013, 11 (20), pp.3282-3287. ⟨10.1039/c3ob27404g⟩. ⟨hal-00949977⟩

Nicolas Chéron, Romain Ramozzi, Laurent El Kaim, Laurence Grimaud, Paul Fleurat-Lessard. Substituent Effects in Ugi–Smiles Reactions. Journal of the Chemical Society, Faraday Transactions 1: Physical Chemistry in Condensed Phases, The Royal Society of Chemistry, 2013, 117 (33), pp.8035-8042. ⟨10.1021/jp4052227⟩. ⟨hal-01116243⟩

Laurent El Kaim, Laurence Grimaud, Patil Pravin. Ugi-Smiles couplings of 4-substituted pyridine derivatives: A fast access to chloroquine analogues. Organic Letters, American Chemical Society, 2012, 14 (2), pp.476-478. ⟨10.1021/ol202974w⟩. ⟨hal-00949992⟩

Madjid Sidhoum, Laurent El Kaim, Laurence Grimaud. Ugi-Smiles Coupling of Thiouracil Derivatives towards 2,4-Diamino Pyrimidines. SYNLETT, Georg Thieme Verlag, 2012, 23 (04), pp.632 - 636. ⟨10.1055/s-0031-1290347⟩. ⟨hal-01664771⟩

Laurent El Kaim, Laurence Grimaud, Srinivas Purumandla. Four-Component Synthesis of Indazole through Ugi-Azide Coupling. SYNLETT, Georg Thieme Verlag, 2012, 2012 (02), pp.295 - 297. ⟨10.1055/s-0031-1290075⟩. ⟨hal-01664772⟩

Aurélie dos Santos, Laurent El Kaim, Laurence Grimaud, Romain Ramozzi. Palladium-catalyzed ring opening of aminocyclopropyl Ugi adducts. SYNLETT, Georg Thieme Verlag, 2012, pp.438-442. ⟨10.1055/s-0031-1290312⟩. ⟨hal-00949987⟩

Laurent El Kaim, Laurence Grimaud, Pravin Patil. Oxazole Synthesis from Isocyanides. SYNLETT, Georg Thieme Verlag, 2012, 23 (9), pp.1361-1363. ⟨10.1055/s-0031-1290939⟩. ⟨hal-00949986⟩

Nicolas Chéron, Romain Ramozzi, Laurent El Kaim, Laurence Grimaud, Paul Fleurat-Lessard. Challenging 50 Years of Established Views on Ugi Reaction: A Theoretical Approach. Journal of Organic Chemistry, American Chemical Society, 2012, 77 (3), pp.1361-1366. ⟨10.1021/jo2021554⟩. ⟨hal-01116252⟩

Laurent El Kaim, Laurence Grimaud, Pravin Patil. Three-Component Strategy toward 5-Membered Heterocycles from Isocyanide Dibromides.. Organic Letters, American Chemical Society, 2011, 13 (5), pp.1261 - 1263. ⟨10.1021/ol200003u⟩. ⟨hal-01664777⟩

Laurent El Kaim, Laurence Grimaud, X. Le Goff, Aurelie Schiltz. Smiles Cascades toward Heterocyclic Scaffolds. Organic Letters, American Chemical Society, 2011, pp.534-536. ⟨hal-00695039⟩

Aurélie dos Santos, Laurent El Kaim, Laurence Grimaud, Caroline Ronsseray. Copper-catalyzed aerobic oxidative cyclization of hydrazones to pyrazolidinones. European Journal of Organic Chemistry, Wiley-VCH Verlag, 2011, 2011 (17), pp.3117-3121. ⟨10.1002/ejoc.201100261⟩. ⟨hal-00950011⟩

Aurélie dos Santos, Laurence Grimaud, Caroline Ronsseray, Didier Coffinier, Laurent El Kaim, et al.. A new multicomponent reaction for the synthesis of pyridines via cycloaddition of azadienes and ketenimines. Tetrahedron Letters, Elsevier, 2011, 52 (23), pp.3023 - 3025. ⟨10.1016/j.tetlet.2011.04.007⟩. ⟨hal-01664785⟩

Laurent El Kaim, Laurence Grimaud, Srinivas Reddy Purumandla. Phosphite-mediated synthesis of benzimidazoles: A one-pot four-component approach from nitrophenols. European Journal of Organic Chemistry, Wiley-VCH Verlag, 2011, - (31), pp.6177-6180. ⟨10.1002/ejoc.201100939⟩. ⟨hal-00951232⟩

Aurélie dos Santos, Laurent El Kaim, Laurence Grimaud, Caroline Ronsseray. Ugi post-condensation copper-triggered oxidative cascade towards pyrazoles. Beilstein Journal of Organic Chemistry, Beilstein-Institut, 2011, 7, pp.1310-1314. ⟨10.3762/bjoc.7.153⟩. ⟨hal-00951236⟩

Laurent El Kaim, Laurence Grimaud, Srinivas Reddy Purumandla. Multicomponent synthesis of fused benzimidazolopiperazines. Journal of Organic Chemistry, American Chemical Society, 2011, 76 (11), pp.4728-4733. ⟨10.1021/jo200397m⟩. ⟨hal-00951229⟩

Laurent El Kaim, Laurence Grimaud, Simon Wagschal. Palladium catalyzed ring opening of furans as a route to α,β-unsaturated aldehydes. Chemical Communications, Royal Society of Chemistry, 2011, 47 (6), pp.1887 - 1889. ⟨10.1039/C0CC04164E⟩. ⟨hal-01664788⟩

Laurent El Kaim, Laurence Grimaud, X. Le Goff, M. Menes-Arzate, Ld Miranda. Straightforward four-component access to spiroindolines. Chemical Communications, Royal Society of Chemistry, 2011, pp.8145-8147. ⟨hal-00695235⟩

Laurent El Kaim, Laurence Grimaud, Srinivas Reddy Purumandla, Srinivas Purumandla. Allyl and Benzyl Dance under Basic Conditions. SYNLETT, Georg Thieme Verlag, 2011, 2011 (13), pp.1816 - 1820. ⟨10.1055/s-0030-1260964⟩. ⟨hal-01664781⟩

Laurent El Kaim, Laurence Grimaud, Patil Pravin. Xanthate based radical cascade toward multicomponent formation of pyrrolopyrimidines. Molecules, MDPI, 2011, 16 (11), pp.9261-9273. ⟨10.3390/molecules16119261⟩. ⟨hal-00951237⟩

Laurent El Kaim, Laurence Grimaud, Patil Pravin. Xanthate Based Radical Cascade Toward Multicomponent Formation of Pyrrolopyrimidines. Molecules, MDPI, 2011, 16 (12), pp.9261 - 9273. ⟨10.3390/molecules16119261⟩. ⟨hal-01664773⟩

Nicolas Chéron, Laurent El Kaim, Laurence Grimaud, Paul Fleurat-Lessard. A Density Functional Theory Study of the Nef-Isocyanide Reaction: Mechanism, Influence of Parameters and Scope. Journal of Physical Chemistry A, American Chemical Society, 2011, 115 (35), pp.10106 - 10112. ⟨10.1021/jp205909d⟩. ⟨hal-01664774⟩

Nicolas Chéron, Laurent El Kaim, Laurence Grimaud, Paul Fleurat-Lessard. Evidences for the Key Role of Hydrogen Bonds in Nucleophilic Aromatic Substitution Reactions. Chemistry - A European Journal, Wiley-VCH Verlag, 2011, 17 (52), pp.14929-14934. ⟨10.1002/chem.201102463⟩. ⟨hal-01116254⟩

Anaelle Barthelon, X. Le Goff, Laurent El Kaim, Laurence Grimaud. Four-Component Synthesis of Imidazolinium-Fused Heterocycles from Ugi-Smiles Couplings (pub). SYNLETT, Georg Thieme Verlag, 2010, 1, pp.153-157. ⟨hal-00577187⟩

Laurent El Kaim, Laurence Grimaud, Aurelie Schiltz. Isocyanide-Based Multicomponent Reaction ‘without’ Isocyanides. SYNLETT, Georg Thieme Verlag, 2009, 2009 (09), pp.1401 - 1404. ⟨10.1055/s-0029-1217184⟩. ⟨hal-01671034⟩

Laurent El Kaim, Laurence Grimaud. Beyond the Ugi reaction: less conventional interactions between isocyanides and iminium species. Tetrahedron, Elsevier, 2009, 65 (11), pp.2153 - 2171. ⟨10.1016/j.tet.2008.12.002⟩. ⟨hal-01671037⟩

Laurent El Kaim, Laurent El Kaïm, Laurence Grimaud, Julie Oble, Simon Wagschal. Three-component Ugi–Smiles couplings of cyclic imines. Tetrahedron Letters, Elsevier, 2009, 50 (15), pp.1741 - 1743. ⟨10.1016/j.tetlet.2009.01.145⟩. ⟨hal-01671038⟩

Laurent El Kaim, Didier Coffinier, Laurence Grimaud. New Benzotriazole and Benzimidazole Scaffolds from Ugi−Smiles Couplings of Isocyanides. Organic Letters, American Chemical Society, 2009, 11 (4), pp.995 - 997. ⟨10.1021/ol8029438⟩. ⟨hal-01671039⟩

Laurent El Kaim, Laurence Grimaud, Simon Wagschal. Three-Component Nef-Huisgen Access to 1,2,4-Triazoles. SYNLETT, Georg Thieme Verlag, 2009, 2009 (08), pp.1315 - 1317. ⟨10.1055/s-0028-1216738⟩. ⟨hal-01671035⟩

Laurent El Kaim, Laurent El Kaim, Laurence Grimaud, Aurelie Schiltz. One-pot synthesis of oxazoles using isocyanide surrogates. Tetrahedron Letters, Elsevier, 2009, 50 (37), pp.5235 - 5237. ⟨10.1016/j.tetlet.2009.07.001⟩. ⟨hal-01671029⟩

Laurent El Kaim, Laurence Grimaud, Aurelie Schiltz. “Isocyanide-free” Ugi reactions. Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2009, 7 (15), ⟨10.1039/B908541F⟩. ⟨hal-01671030⟩

Laurent El Kaim, Aurélie dos Santos, Laurence Grimaud, Caroline Ronsseray. Unconventional oxazole formation from isocyanides. Chemical Communications, Royal Society of Chemistry, 2009, ⟨10.1039/b904699b⟩. ⟨hal-01671031⟩

Laurent El Kaim, Didier Coffinier, Laurence Grimaud. Isocyanide-Based Two-Step Three-Component Keteneimine Formation. Organic Letters, American Chemical Society, 2009, 11 (8), pp.1825 - 1827. ⟨10.1021/ol9004432⟩. ⟨hal-01671032⟩

Laurent El Kaim, Marion Gizzi, Laurence Grimaud. New MCR−Heck−Isomerization Cascade toward Indoles. Organic Letters, American Chemical Society, 2008, 10 (16), pp.3417 - 3419. ⟨10.1021/ol801217a⟩. ⟨hal-01671043⟩

Laurent El Kaim, Anaelle Barthelon, Marie Gizolme, Laurence Grimaud. Thiols in Ugi- and Passerini-Smiles-Type Couplings. European Journal of Organic Chemistry, Wiley-VCH Verlag, 2008, 2008 (35), pp.5974 - 5987. ⟨10.1002/ejoc.200800859⟩. ⟨hal-01671040⟩

Laurent El Kaim, Anaelle Barthelon, Aurélie Dos Santos, Laurent El Kaïm, Laurence Grimaud. Ugi/Smiles access to pyrazine scaffolds. Tetrahedron Letters, Elsevier, 2008, 49 (20), pp.3208 - 3211. ⟨10.1016/j.tetlet.2008.03.100⟩. ⟨hal-01671046⟩

Laurent El Kaim, Didier Coffinier, Laurence Grimaud. Isocyanide Addition to Acylphosphonates: A Formal Passerini Reaction of Acyl Chlorides. SYNLETT, Georg Thieme Verlag, 2008, 2008 (8), pp.1133 - 1136. ⟨10.1055/s-2008-1072726⟩. ⟨hal-01671047⟩

Laurent El Kaim, Rocio Gamez-Montaño, Laurence Grimaud, Tannya Ibarra-Rivera. New palladium-catalyzed aerobic oxidative cleavage and cyclization of N-aryl peptide derivatives. Chemical Communications, Royal Society of Chemistry, 2008, ⟨10.1039/B716849G⟩. ⟨hal-01671048⟩

Laurent El Kaim, Laurence Grimaud, Emilie Vieu. From simple Ugi adducts to indanes and amidomalonates: new manganese (III) induced radical cascades. Organic Letters, American Chemical Society, 2007, 9, Asap. ⟨hal-00176934⟩

M. Gageat, L. Gaultier, Laurent El Kaim, Laurence Grimaud. New Ugi/Pictet–Spengler multicomponent formation of polycyclic diketopiperazines from isocyanides and a-keto acids. SYNLETT, Georg Thieme Verlag, 2007, pp.500. ⟨hal-00176919⟩

Laurent El Kaim, Marie Gizolme, Laurence Grimaud. New indolizines template from the Ugi reaction.. SYNLETT, Georg Thieme Verlag, 2007, pp.227. ⟨hal-00176920⟩

Laurent El Kaim, Marie Gizolme, Laurence Grimaud, Julie Oble. Smiles rearrangement in Ugi and Passerini type couplings: new multicomponent accesses to O- and N-arylamides. Journal of Organic Chemistry, American Chemical Society, 2007, 72, pp.4169. ⟨hal-00176917⟩

Laurent El Kaim, Marie Gizolme, Laurence Grimaud, Julie Oble. New benzothiazole and benzoxazole scaffolds from the Ugi–Smiles couplings of heterocyclic thiols. SYNLETT, Georg Thieme Verlag, 2007, pp.465. ⟨hal-00176918⟩

Julie Oble, Laurent El Kaim, Marion Gizzi, Laurence Grimaud. Ugi-Smiles access to quinoxalines derivatives.. Heterocycles, The Japan Institute of Heterocyclic Chemistry, 2007, pp.667. ⟨hal-00176915⟩

Laurent El Kaim, Marie Gizolme, Laurence Grimaud, Julie Oble. New Ugi-Smiles-metathesis strategy towards the synthesis of pyrimido azepines.. Journal of Organic Chemistry, American Chemical Society, 2007, 72, pp.5835. ⟨hal-00176916⟩

Emilie Vieu, Luis D. Miranda, Laurent El Kaim, Laurence Grimaud. Ugi /xanthate cyclisations as a radical route to lactam scaffolds. Tetrahedron Letters, Elsevier, 2006, 47, pp.8259. ⟨hal-00176921⟩

S. Hadrot, Laurent El Kaim, Laurence Grimaud. Solvent free preparation of amidophosphonates from isocyanides. Tetrahedron Letters, Elsevier, 2006, 47, pp.3945. ⟨hal-00176925⟩

Laurent El Kaim, Marie Gizolme, Laurence Grimaud. O-Arylative Passerini reaction. Organic Letters, American Chemical Society, 2006, 8, pp.5021. ⟨hal-00176923⟩

Laurent El Kaim, Marie Gizolme, Laurence Grimaud, Julie Oble. Direct access to heterocyclic scaffolds by new multicomponent Ugi Smiles coupling. Organic Letters, American Chemical Society, 2006, 8, pp.4019. ⟨hal-00176922⟩

Laurent El Kaim, Laurence Grimaud, Julie Oble. New ortho-quinone methide formation: application to three-component coupling of isocyanides, aldehydes and phenols. Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2006, 4, pp.3410. ⟨hal-00176924⟩

Aurélie dos Santos, Laurent El Kaim, L. Gaultier, Laurence Grimaud. Formation of new phosphates from aldehydes by a DBU-catalysed Phospha-Brook rearrangement in a polar solvent. SYNLETT, Georg Thieme Verlag, 2005, pp.2335. ⟨hal-00176928⟩

H. Dupont, S. Oualef, Laurent El Kaim, Laurence Grimaud, E. Vedrenne. Dramatic effect of boron-based Lewis acid in cross-metathesis reactions. SYNLETT, Georg Thieme Verlag, 2005, pp.670. ⟨hal-00176929⟩

Laurent El Kaim, Laurence Grimaud, Julie Oble. Phenol-Ugi-Smiles Systems: Highly efficient strategies for the multicomponent N-arylation of primary amines with isocyanides, aldehydes and phenols. Angewandte Chemie, Wiley-VCH Verlag, 2005, 44, pp.7165. ⟨hal-00176926⟩

F. Royer, E. Vedrenne, Laurent El Kaim, Laurence Grimaud, Julie Oble. Towards the Synthesis of Paulitin: New Insights into the Enyne-Metathesis Mechanism. SYNLETT, Georg Thieme Verlag, 2005, pp.2379. ⟨hal-00176927⟩

A. Lee, Y. Perroux, C. Tirla, Laurent El Kaim, Laurence Grimaud. First carbamates conversion to amides by simple alkyl group transfer from trialkylalanes. Organic Letters, American Chemical Society, 2004, 6, pp.381. ⟨hal-00176932⟩

Laurent El Kaim, L. Gaultier, Laurence Grimaud, Emilie Vieu. From isocyanides to trichloropyruvamides : Application to new preparation of Oxamide derivatives. Tetrahedron Letters, Elsevier, 2004, 45, pp.8047. ⟨hal-00176931⟩

T. Colin, L. Gatay, Laurent El Kaim, L. Gaultier, Laurence Grimaud. New access to fluorinated ketoglycolic acid derivatives from trifluoropyruvamides. Tetrahedron Letters, Elsevier, 2004, 45, pp.5611. ⟨hal-00176930⟩

V. Michaut, V. Baillez, Laurent El Kaim. New straightforward quinoline synthesis from the Mannich reaction of ketohydrazones. Synthetic Communications, Taylor & Francis: STM, Behavioural Science and Public Health Titles, 2004, 34, pp.109. ⟨hal-00176933⟩