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Researcher identifiers

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    Open access quantity

    47 %

    Number of documents

    38

    Laetitia Dou


    C2VN Centre de Recherche en CardioVasculaire et Nutrition
    Aix-Marseille université, INSERM, INRAE


    Journal articles33 documents

    • Guillaume Lano, Marion Sallée, Marion Pelletier, Stanislas Bataille, Megan Fraisse, et al.. Neutrophil:lymphocyte ratio correlates with the uremic toxin indoxyl sulfate and predicts the risk of death in patients on hemodialysis. Nephrology Dialysis Transplantation, Oxford University Press, 2022, ⟨10.1093/ndt/gfab350⟩. ⟨hal-03670071⟩
    • Laetitia Dou, Stéphane Burtey. Reversing endothelial dysfunction with empagliflozin to improve cardiomyocyte function in cardiorenal syndrome. Kidney International, Nature Publishing Group, 2021, 99 (5), pp.1062-1064. ⟨10.1016/j.kint.2021.01.008⟩. ⟨hal-03256334⟩
    • Guillaume Lano, Manon Laforêt, Clarissa Von Kotze, Justine Perrin, Tawfik Addi, et al.. Aryl Hydrocarbon Receptor Activation and Tissue Factor Induction by Fluid Shear Stress and Indoxyl Sulfate in Endothelial Cells. International Journal of Molecular Sciences, MDPI, 2020, 21 (7), pp.2392. ⟨10.3390/ijms21072392⟩. ⟨hal-02526006⟩
    • Laetitia Dou, Noemie Jourde-Chiche. toxins Endothelial Toxicity of High Glucose and its by-Products in Diabetic Kidney Disease. Toxins, MDPI, 2019, 11 (10), pp.578. ⟨10.3390/toxins11100578⟩. ⟨hal-02708220⟩
    • Tawfik Addi, Stéphane Poitevin, Nathalie Mckay, Kamel Eddine El Mecherfi, Omar Kheroua, et al.. Mechanisms of tissue factor induction by the uremic toxin indole-3 acetic acid through aryl hydrocarbon receptor/nuclear factor-kappa B signaling pathway in human endothelial cells. Archives of Toxicology, Springer Verlag, 2019, 93 (1), pp.121-136. ⟨10.1007/s00204-018-2328-3⟩. ⟨hal-02060898⟩
    • Noemie Jourde-Chiche, Fadi Fakhouri, Laetitia Dou, Jeremy Bellien, Stéphane Burtey, et al.. Endothelium structure and function in kidney health and disease. Nature Reviews Nephrology, Nature Publishing Group, 2019, 15 (2), pp.87-108. ⟨10.1038/s41581-018-0098-z⟩. ⟨inserm-02160201⟩
    • Laetitia Dou, Stéphane Poitevin, Marion Sallée, Tawfik Addi, Bertrand Gondouin, et al.. Aryl hydrocarbon receptor is activated in patients and mice with chronic kidney disease. Kidney International, Nature Publishing Group, 2018, 93 (4), pp.986-999. ⟨10.1016/j.kint.2017.11.010⟩. ⟨hal-02060310⟩
    • Laetitia Dou, Stéphane Burtey. The harmful effect of indoxyl sulfate on neovascularization in chronic kidney disease. Kidney International, Nature Publishing Group, 2016, 89, pp.532-534. ⟨10.1016/j.kint.2015.12.030⟩. ⟨hal-01464929⟩
    • Bertrand Gondouin, Noemie Jourde-Chiche, Marion Sallée, Laetitia Dou, Claire Cerini, et al.. Plasma Xanthine Oxidase Activity Is Predictive of Cardiovascular Disease in Patients with Chronic Kidney Disease, Independently of Uric Acid Levels. Nephron Physiology, Karger, 2015, 131 (3), pp.167-174. ⟨10.1159/000441091⟩. ⟨hal-01610424⟩
    • Laetitia Dou, Marion Sallée, Claire Cerini, Stéphane Poitevin, Bertrand Gondouin, et al.. The Cardiovascular Effect of the Uremic Solute Indole-3 Acetic Acid. Journal of the American Society of Nephrology, American Society of Nephrology, 2015, 26 (4), pp.876-887. ⟨10.1681/ASN.2013121283⟩. ⟨hal-01610425⟩
    • Marion Sallée, Laetitia Dou, Claire Cerini, Stéphane Poitevin, Philippe Brunet, et al.. The Aryl Hydrocarbon Receptor-Activating Effect of Uremic Toxins from Tryptophan Metabolism: A New Concept to Understand Cardiovascular Complications of Chronic Kidney Disease. Toxins, MDPI, 2014, 6 (3), pp.934-949. ⟨10.3390/toxins6030934⟩. ⟨hal-01610428⟩
    • Bertrand Gondouin, Claire Cerini, Laetitia Dou, Marion Sallée, Ariane Duval-Sabatier, et al.. Indolic uremic solutes increase tissue factor production in endothelial cells by the aryl hydrocarbon receptor pathway. Kidney International, Nature Publishing Group, 2013, 84 (4), pp.733-744. ⟨10.1038/ki.2013.133⟩. ⟨hal-01610430⟩
    • Noemie Jourde-Chiche, Laetitia Dou, Claire Cerini, Francoise Dignat-George, Philippe Brunet. Vascular Incompetence in Dialysis Patients-Protein-Bound Uremic Toxins and Endothelial Dysfunction. Seminars in Dialysis, Wiley, 2011, 24 (3), pp.327-337. ⟨10.1111/j.1525-139X.2011.00925.x⟩. ⟨hal-01610435⟩
    • Raymond Calaf, Claire Cerini, Cecile Genovesio, Pierre Verhaeghe, Noemie Jourde-Chiche, et al.. Determination of uremic solutes in biological fluids of chronic kidney disease patients by HPLC assay. Journal of Chromatography B - Analytical Technologies in the Biomedical and Life Sciences, Elsevier, 2011, 879 (23), pp.2281-2286. ⟨10.1016/j.jchromb.2011.06.014⟩. ⟨hal-01460285⟩
    • Philippe Brunet, Bertrand Gondouin, Ariane Duval-Sabatier, Laetitia Dou, Claire Cerini, et al.. Does Uremia Cause Vascular Dysfunction?. Kidney and Blood Pressure Research, Karger, 2011, 34 (4), pp.284-290. ⟨10.1159/000327131⟩. ⟨hal-01610434⟩
    • Chahrazad Moubarik, Benjamin Guillet, Bennis Youssef, Jean-Laurent Codaccioni, Marie-Dominique Piercecchi, et al.. Transplanted Late Outgrowth Endothelial Progenitor Cells as Cell Therapy Product for Stroke. Stem Cell Reviews and Reports, Humana Press, 2011, 7 (1), pp.208-220. ⟨10.1007/s12015-010-9157-y⟩. ⟨hal-03670118⟩
    • Eva Schepers, Griet Glorieux, Laetitia Dou, Claire Cerini, Nathalie Gayrard, et al.. Guanidino Compounds as Cause of Cardiovascular Damage in Chronic Kidney Disease: An in vitro Evaluation. Blood Purification, Karger, 2010, 30 (4), pp.277-287. ⟨10.1159/000320765⟩. ⟨hal-01610436⟩
    • Noemie Jourde-Chiche, Laetitia Dou, Florence Sabatier, R. Calaf, Claire Cerini, et al.. Levels of circulating endothelial progenitor cells are related to uremic toxins and vascular injury in hemodialysis patients. Journal of Thrombosis and Haemostasis, Wiley, 2009, 7 (9), pp.1576-1584. ⟨10.1111/j.1538-7836.2009.03540.x⟩. ⟨hal-01610439⟩
    • Noemie Jourde-Chiche, Laetitia Dou, Claire Cerini, Francoise Dignat-George, Raymond Vanholder, et al.. Protein-Bound Toxins-Update 2009. Seminars in Dialysis, Wiley, 2009, 22 (4), pp.334-339. ⟨10.1111/j.1525-139X.2009.00576.x⟩. ⟨hal-01610438⟩
    • Laurent Daniel, Laetitia Dou, Yvon Berland, Philippe Lesavre, Lise Mecarelli-Halbwachs, et al.. Circulating microparticles in renal diseases. Nephrology Dialysis Transplantation, Oxford University Press, 2008, 23 (7), pp.2129-2132. ⟨10.1093/ndt/gfn029⟩. ⟨hal-01610440⟩
    • G. Cohen, G. Glorieux, P. Thornalley, E. Schepers, N. Meert, et al.. Review on uraemic toxins III: recommendations for handling uraemic retention solutes in vitro towards a standardized approach for research on uraemia. Nephrology Dialysis Transplantation, Oxford University Press, 2007, 22 (12), pp.3381-3390. ⟨10.1093/ndt/gfm210⟩. ⟨hal-03670130⟩
    • Laetitia Dou, Noemie Jourde-Chiche, V. Faure, Claire Cerini, Yvon Berland, et al.. The uremic solute indoxyl sulfate induces oxidative stress in endothelial cells. Journal of Thrombosis and Haemostasis, Wiley, 2007, 5 (6), pp.1302-1308. ⟨10.1111/j.1538-7836.2007.02540.x⟩. ⟨hal-01610441⟩
    • V Faure, Laetitia Dou, F Sabatier, Claire Cerini, J Sampol, et al.. Elevation of circulating endothelial microparticles in patients with chronic renal failure. Journal of Thrombosis and Haemostasis, Wiley, 2006, 4 (3), pp.566-573. ⟨10.1111/j.1538-7836.2005.01780.x⟩. ⟨hal-01610442⟩
    • Véronique Wernert, Oliver Schäf, Valérie Faure, Philippe Brunet, Laetitia Dou, et al.. Adsorption of the uremic toxin p-cresol onto hemodialysis membranes and microporous adsorbent zeolite silicalite. African Journal of Biotechnology, Academic Journals, 2006, 123 (2), pp.164-173. ⟨10.1016/j.jbiotec.2005.11.009⟩. ⟨hal-02011745⟩
    • Claire Cerini, Laetitia Dou, F Anfosso, F Sabatier, S Moal, et al.. P-cresol, a uremic retention solute, alters the endothelial barrier function in vitro. Thrombosis and Haemostasis, Schattauer, 2004, 92 (1), pp.140-150. ⟨10.1160/th03-07-0491⟩. ⟨hal-01610445⟩
    • Laetitia Dou, E Bertrand, Claire Cerini, V Faure, J Sampol, et al.. The uremic solutes p-cresol and indoxyl sulfate inhibit endothelial proliferation and wound repair. Kidney International, Nature Publishing Group, 2004, 65 (2), pp.442-451. ⟨10.1111/j.1523-1755.2004.00399.x⟩. ⟨hal-01610444⟩
    • Philippe Brunet, Laetitia Dou, Claire Cerini, Yvon Berland. Protein-bound uremic retention solutes. Advances in Renal Replacement Therapy, Elsevier - WB Saunders, 2003, 10 (4), pp.310-320. ⟨10.1053/j.arrt.2003.08.002⟩. ⟨hal-01610447⟩
    • Valérie Moal, Philippe Brunet, Laetitia Dou, S Morange, J Sampol, et al.. Impaired expression of glycoproteins on resting and stimulated platelets in uraemic patients. Nephrology Dialysis Transplantation, Oxford University Press, 2003, 18 (9), pp.1834-1841. ⟨10.1093/ndt/gfg185⟩. ⟨hal-01610446⟩
    • Laetitia Dou, Claire Cerini, Philippe Brunet, C Guilianelli, V Moal, et al.. P-cresol, a uremic toxin, decreases endothelial cell response to inflammatory cytokines. Kidney International, Nature Publishing Group, 2002, 62 (6), pp.1999-2009. ⟨10.1046/j.1523-1755.2002.t01-1-00651.x⟩. ⟨hal-01610448⟩
    • P Galea, V Frances, Laetitia Dou, J Sampol, J Chermann. Role of Kaposi's sarcoma cells in recruitment of circulating leukocytes: implications in pathogenesis. Journal of Human Virology, Lippincott Williams & Wilkins (LWW), 1998, 1 (4), pp.273-81. ⟨hal-03670152⟩
    • Laetitia Dou, Philippe Brunet, Francoise Dignat-George, J Sampol, Yvon Berland. Effect of uremia and hemodialysis on soluble L-selectin and leukocyte surface CD11b and L-selectin. American Journal of Kidney Diseases, Elsevier, 1998, 31 (1), pp.67-73. ⟨10.1053/ajkd.1998.v31.pm9428454⟩. ⟨hal-01610449⟩
    • Arsène Bikoue, Claude d'Ercole, Françoise George, Laetitia Dameche, Murielle Mutin, et al.. Quantitative Analysis of Leukocyte Membrane Antigen Expression on Human Fetal and Cord Blood: Normal Values and Changes during Development. Clinical immunology and immunopathology, Elsevier - Academic Press;Elsevier, 1997, 84 (1), pp.56-64. ⟨10.1006/clin.1997.4366⟩. ⟨hal-03670166⟩
    • Laetitia Dameche, Philippe Brunet, Francoise Dignat-George, S Andre-Pinon, D Bernard, et al.. Meltspun cellulose diacetate and polysulfone membranes have the same effect on complement activation and expression of leukocyte adhesion molecules and complement receptors. Nephrology Dialysis Transplantation, Oxford University Press, 1995, 10 (10), pp.33-38. ⟨hal-01610451⟩

    Conference papers5 documents

    • Philippe Brunet, Laetitia Dou, Francoise Dignat-George, J Sampol, Yvon Berland. Polymorphonuclear activation measured by surface expression of CD11b and CD62L in uremic patients.. France. pp.A0313. ⟨hal-01610450⟩
    • Marion Sallée, Laetitia Dou, Claire Cerini, Stéphane Poitevin, Bertrand Gondouin, et al.. Indole-3 acetic acid predicts cardiovascular event and mortality in chronic kidney disease patients: evidence for an endothelial inflammatory and prooxidant effect. 51st Congress of the European-Renal-Association(ERA)/European-Dialysis-and-Transplant-Association (EDTA), May 2014, Amsterdam, Netherlands. pp.163. ⟨hal-01610429⟩
    • Laetitia Dou, Bertrand Gondouin, Claire Cerini, Stéphane Poitevin, Philippe Brunet, et al.. The uremic toxin indole-3-acetic acid induces endothelial cox-2 expression by increasing oxidative stress. 49th Congress of the European-Renal-Association/European-Dialysis-and-Transplant-Association (ERA-EDTA), May 2012, Paris, France. pp.84. ⟨hal-01610431⟩
    • Claire Cerini, Bertrand Gondouin, Laetitia Dou, Ariane Duval-Sabatier, Philippe Brunet, et al.. Role of indole-derived uremic solutes on tissue factor production via aryl hydrocarbon receptor pathway. 49th Congress of the European-Renal-Association/European-Dialysis-and-Transplant-Association (ERA-EDTA), May 2012, Paris, France. pp.77. ⟨hal-01610432⟩
    • V Faure, Laetitia Dou, F Sabatier, Claire Cerini, J Sampol, et al.. Elevation of endothelial microparticles in chronic renal failure: Role of uremic toxins. 42nd Annual Meeting of the European-Renal-Association/European-Dialysis-and-Transplant-Association (ERA-EDTA), Jun 2005, Istanbul, Turkey. pp.V63-V64. ⟨hal-01610443⟩