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Successes, surprises and pitfalls in modular polyketide synthase engineering
Kira J. Weissman
,
Li Su
,
Laurence Hôtel
,
Cédric Paris
,
Clara Chepkirui
,
et al.
2nd International Conference on Biomolecules and the Bioeconomy, Nov 2021, Nancy, France
Communication dans un congrès
hal-03525292v1
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Engineering of a polyketide synthase leads to 'low-fat' stambomycins
Li Su
,
Laurence Hôtel
,
Cédric Paris
,
Christophe Jacob
,
Bertrand Aigle
,
et al.
Journées francophones d'actinobactéries (ACTINO 2020), Dec 2020, On-line, France
Communication dans un congrès
hal-03525244v1
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The structural biology of modular polyketide synthases: insights and implications for synthetic biology
Kira J. Weissman
,
Jonathan Dorival
,
Thibault Annaval
,
Fanny Risser
,
Sabrina Collin
,
et al.
European Workshop on Natural Product Biosynthesis, Jun 2017, Gif-sur-Yvete, France
Communication dans un congrès
hal-01736000v1
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The use of Saccharomyces cerevisiae as a toolbox for understanding how polyketide synthases function
Christophe Jacob
,
Jean-Malo Massicard
,
Sabrina Collin
,
Kira J. Weissman
13th International conference "Levures, modèles et outils", Sep 2018, Rheinau, Switzerland
Communication dans un congrès
hal-02070073v1
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Editorial overview: Macromolecular assemblies: Assembly, dynamics and control of activity
Timm Maier
,
Kira J. Weissman
Article dans une revue
hal-02956617v1
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Generation of analogues of stambomycins by genetic engineering and allied approaches
Li Su
,
Laurence Hôtel
,
Cédric Paris
,
Christophe Jacob
,
Bertrand Aigle
,
et al.
15. Congrès National de la SFM (Société Française de Microbiologie), Oct 2019, Paris, France
Communication dans un congrès
hal-03666910v1
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Polyketides: applications in therapy and agriculture, development of new analogues using synthetic biology
Kira J. Weissman
2018
Autre publication scientifique
hal-03525977v1
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Deciphering the structures of trans-AT polyketide synthase megaenzymes
Kira J. Weissman
2016
Autre publication scientifique
hal-03526010v1
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Engineering the stambomycin modular polyketide synthase yields 37-membered mini-stambomycins
Li Su
,
Laurence Hôtel
,
Cédric Paris
,
Clara Chepkirui
,
Alexander Brachmann
,
et al.
Article dans une revue
hal-03544763v1
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Genome mining: accessing Nature’s natural product diversity
Kira J Weissman
Biomolecules: Research & Development, Markets and Acceptability, 2019, Palma de Majorca, Spain
Communication dans un congrès
hal-03016889v1
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Characterization of Intersubunit Communication in the Virginiamycin trans-AT Polyketide Synthase
Jonathan Dorival
,
Thibault Annaval
,
Fanny Risser
,
Sabrina Collin
,
Pierre Roblin
,
et al.
Directing Biosynthesis V, Mar 2017, Warwick, United Kingdom
Poster de conférence
hal-01735993v1
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Polyketide stereocontrol: a study in chemical biology
Kira J. Weissman
Article dans une revue
hal-01671019v1
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The structural biology of biosynthetic megaenzymes
Kira J Weissman
Article dans une revue
hal-01474060v1
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Creating analogues of the anti-tumor polyketide stambomycins by genetic engineering and allied approaches
Li Su
,
Hotel L
,
Christophe Jacob
,
Kira J Weissman
,
Bertrand Aigle
2018, 2018, Nancy, France
Poster de conférence
hal-03016980v1
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The structural biology of modular polyketide synthases: insights and implications for synthetic biology
Kira J Weissman
,
Jack Davison
,
Jonathan Dorival
,
Thibault Annaval
,
Fanny Risser
,
et al.
3rd European Conference on Natural Products, 2018, Frankfurt, Germany
Communication dans un congrès
hal-02956684v1
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Probing interactions in fungal PKS
Kira J Weissman
Article dans une revue
hal-01467279v1
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Modular Oxime Formation by a trans‐AT Polyketide Synthase
Hannah Minas
,
Romain François
,
Franziska Hemmerling
,
Amy Fraley
,
Cora Dieterich
,
et al.
Article dans une revue
hal-04307564v1
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Function of polyketide synthases from the SAXS structure of a complete module
Jack Davison
,
Jonathan Dorival
,
Hery Rabeharindranto
,
Hortense Mazon
,
Benjamin Chagot
,
et al.
Article dans une revue
hal-01653555v1
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Manipulating polyketide stereochemistry by exchange of polyketide synthase modules
Jean-Malo Massicard
,
Claire Soligot
,
Kira J. Weissman
,
Christophe Jacob
Article dans une revue
hal-02937132v1
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Bacterial Type I Polyketide Synthases
Kira J. Weissman
Chapitre d'ouvrage
hal-02956621v1
|
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Structure-function relationships in modular PKSs and their application to genetic engineering
Kira J. Weissman
2020
Autre publication scientifique
hal-03525856v1
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Towards improved understanding of intersubunit interactions in modular polyketide biosynthesis: Docking in the enacyloxin IIa polyketide synthase
Fanny Risser
,
Sabrina Collin
,
Raphael dos Santos-Morais
,
Arnaud Gruez
,
Benjamin Chagot
,
et al.
Article dans une revue
hal-02926190v1
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Evaluating Ketoreductase Exchanges as a Means of Rationally Altering Polyketide Stereochemistry
Thibault Annaval
,
Cedric Paris
,
Peter F. Leadlay
,
Christophe Jacob
,
Kira J. Weissman
Article dans une revue
istex
hal-01278114v1
|
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Biosynthesis of novel desferrioxamine derivatives requires unprecedented crosstalk between separate NRPS-independent siderophore pathways
Li Su
,
Yaouba Souaibou
,
Laurence Hôtel
,
Cédric Paris
,
Kira J Weissman
,
et al.
Article dans une revue
hal-04445176v2
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Deciphering the structures of trans-AT polyketide synthase megaenzymes
Kira J. Weissman
2016
Autre publication scientifique
hal-03526020v1
|
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Unpackaging the Roles of Streptomyces Natural Products
Christophe Jacob
,
Kira J. Weissman
Article dans une revue
hal-01671016v1
|
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The structural biology of modular polyketide synthases: insights and implications for synthetic biology
Kira J. Weissman
2017
Autre publication scientifique
hal-03525991v1
|
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Uncovering the structures of modular polyketide synthases
Kira J. Weissman
Article dans une revue
hal-01474063v1
|
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Decrypting the programming of β-methylation in virginiamycin M biosynthesis
Sabrina Collin
,
Russell Cox
,
Cédric Paris
,
Christophe Jacob
,
Benjamin Chagot
,
et al.
Article dans une revue
hal-04064366v1
|
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Engineering Modular Polyketide Biosynthesis in Streptomyces Using CRISPR/Cas: A Practical Guide
Jean-Malo Massicard
,
Li Su
,
Christophe Jacob
,
Kira Weissman
Article dans une revue
hal-04083104v1
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