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Sulfated glycosaminoglycans mediate prion-like behavior of p53 aggregates

Naoyuki Iwahashi , Midori Ikezaki , Taro Nishikawa , Norihiro Namba , Takashi Ohgita , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (52), pp.33225-33234. ⟨10.1073/pnas.2009931117⟩
Article dans une revue hal-03439413v1
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Apical Membrane Expression of Distinct Sulfated Glycans Is a Characteristic Feature of Ductules and Their Reactive and Neoplastic Counterparts

Hitomi Hoshino , Tomoya Akama , Kenji Uchimura , Mana Fukushima , Akifumi Muramoto , et al.
Journal of Histochemistry and Cytochemistry, 2021, 69 (9), pp.555-573. ⟨10.1369/00221554211035730⟩
Article dans une revue hal-03439373v1
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A Shift in Tissue Stiffness During Hippocampal Maturation Correlates to the Pattern of Neurogenesis and Composition of the Extracellular Matrix

Youngjae Ryu , Misato Iwashita , Wonyoung Lee , Kenji Uchimura , Yoichi Kosodo
Frontiers in Aging Neuroscience, 2021, 13, ⟨10.3389/fnagi.2021.709620⟩
Article dans une revue hal-03439389v1
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Cytoplasmic p53 aggregates accumulated in p53-mutated cancer correlate with poor prognosis

Naoyuki Iwahashi , Midori Ikezaki , Yoshihiro Komohara , Yukio Fujiwara , Tomoko Noguchi , et al.
PNAS Nexus, 2022, 1 (3), ⟨10.1093/pnasnexus/pgac128⟩
Article dans une revue hal-03780185v1
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GlcNAc6ST3 is a keratan sulfate sulfotransferase for the protein-tyrosine phosphatase PTPRZ in the adult brain

N Narentuya , Yoshiko Takeda-Uchimura , Tahmina Foyez , Zui Zhang , Tomoya Akama , et al.
Scientific Reports, 2019, 9 (1), ⟨10.1038/s41598-019-40901-2⟩
Article dans une revue hal-02382855v1
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Structural flexibility of apolipoprotein E-derived arginine-rich peptides improves their cell penetration capability

Yuki Takechi-Haraya , Takashi Ohgita , Akiko Usui , Kazuchika Nishitsuji , Kenji Uchimura , et al.
Scientific Reports, 2023, 13 (1), pp.19396. ⟨10.1038/s41598-023-46754-0⟩
Article dans une revue hal-04304302v1
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Beta3Gn-T7 Is a Keratan Sulfate β1,3 N-Acetylglucosaminyltransferase in the Adult Brain

Yoshiko Takeda-Uchimura , Kazuchika Nishitsuji , Midori Ikezaki , Tomoya O. Akama , Yoshito Ihara , et al.
Frontiers in Neuroanatomy, 2022, 16, pp.813841. ⟨10.3389/fnana.2022.813841⟩
Article dans une revue hal-03676861v1

Targeted delivery of immune therapeutics to lymph nodes prolongs cardiac allograft survival

Baharak Bahmani , Mayuko Uehara , Liwei Jiang , Farideh Ordikhani , Naima Banouni , et al.
Journal of Clinical Investigation, 2018, 128 (11), pp.4770-4786. ⟨10.1172/JCI120923⟩
Article dans une revue hal-02382878v1

Phenotypic and molecular description of an individual with a disruptive variant in the SULF2 gene

Laxmi Kirola , Courtney Edgar-Zarate , Brita Rook , Amy Rowell , Tim Wood , et al.
Clinical Dysmorphology, 2020, 29 (3), pp.144-147. ⟨10.1097/MCD.0000000000000309⟩
Article dans une revue hal-03059966v1
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Enhancement of direct membrane penetration of arginine-rich peptides by polyproline II helix structure

Takashi Ohgita , Yuki Takechi-Haraya , Keisuke Okada , Saki Matsui , Misaki Takeuchi , et al.
Biochimica et Biophysica Acta:Biomembranes, 2020, 1862 (10), pp.183403. ⟨10.1016/j.bbamem.2020.183403⟩
Article dans une revue hal-03059958v1
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Role of MAdCAM-1-Expressing High Endothelial Venule-Like Vessels in Colitis Induced in Mice Lacking Sulfotransferases Catalyzing L-Selectin Ligand Biosynthesis

Shulin Low , Jotaro Hirakawa , Hitomi Hoshino , Kenji Uchimura , Hiroto Kawashima , et al.
Journal of Histochemistry and Cytochemistry, 2018, 66 (6), pp.415-425. ⟨10.1369/0022155417753363⟩
Article dans une revue hal-02382886v1

Glycan sulfation patterns define autophagy flux at axon tip via PTPRσ-cortactin axis

Kazuma Sakamoto , Tomoya Ozaki , Yen-Chun Ko , Cheng-Fang Tsai , Yuanhao Gong , et al.
Nature Chemical Biology, 2019, 15 (7), pp.699-709. ⟨10.1038/s41589-019-0274-x⟩
Article dans une revue hal-02382842v1
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Cell-to-cell transmission of p53 aggregates: a novel player in oncology?

Naoyuki Iwahashi , Midori Ikezaki , Hiroyuki Saito , Kenji Uchimura , Kazuchika Nishitsuji
Molecular & Cellular Oncology, 2021, 8 (2), pp.1892444. ⟨10.1080/23723556.2021.1892444⟩
Article dans une revue hal-03439396v1

Glycosylation changes in inflammatory diseases

Sophie Groux-Degroote , Sumeyye Cavdarli , Kenji Uchimura , Fabrice Allain , Philippe Delannoy
Inflammatory Disorders, in Advances in Protein Chemistry and Structural Biology - Volume 119 - Part A, pp.111-156, 2020, ⟨10.1016/bs.apcsb.2019.08.008⟩
Chapitre d'ouvrage hal-02457451v1
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Iowa Mutant Apolipoprotein A-I (ApoA-IIowa) Fibrils Target Lysosomes

Hirokazu Kameyama , Hiroyuki Nakajima , Kazuchika Nishitsuji , Shiho Mikawa , Kenji Uchimura , et al.
Scientific Reports, 2016, 6, pp.30391. ⟨10.1038/srep30391⟩
Article dans une revue hal-03180614v1
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Extracellular endosulfatase Sulf-2 harbours a chondroitin/dermatan sulfate chain that modulates its enzyme activity

Rana El Masri , Amal Seffouh , Caroline Roelants , Ilham Seffouh , Evelyne Gout , et al.
2021
Pré-publication, Document de travail hal-03099200v1

Edition of heparan sulfate by endosulfatases monitored by HILIC chromatography coupled to mass spectrometry

Nesrine El Omrani , Salomé Poyer , Yoshiko Takeda-Uchimura , Kenji Uchimura , Romain R Vivès , et al.
IMMS 2023, May 2023, Paris, France
Poster de conférence hal-04428436v1
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A novel amphipathic cell-penetrating peptide based on the N-terminal glycosaminoglycan binding region of human apolipoprotein E

Takashi Ohgita , Yuki Takechi-Haraya , Ryo Nadai , Mana Kotani , Yuki Tamura , et al.
Biochimica et Biophysica Acta:Biomembranes, 2019, 1861 (3), pp.541-549. ⟨10.1016/j.bbamem.2018.12.010⟩
Article dans une revue hal-02382859v1

Apical membrane expression of distinct sulfated glycans represents a novel marker of cholangiolocellular carcinoma

Hitomi Hoshino , Makoto Ohta , Makoto Ito , Kenji Uchimura , Yasuhiro Sakai , et al.
Laboratory Investigation; a Journal of Technical Methods and Pathology, 2016, Laboratory Investigation; a Journal of Technical Methods and Pathology, 96 (12), pp.1246-1255. ⟨10.1038/labinvest.2016.104⟩
Article dans une revue hal-03180456v1

Thrombospondin type 1 repeat-derived C-mannosylated peptide attenuates synaptogenesis of cortical neurons induced by primary astrocytes via TGF-β

Kazuchika Nishitsuji , Midori Ikezaki , Shino Manabe , Kenji Uchimura , Yukishige Ito , et al.
Glycoconjugate Journal, 2021, Glycoconjugate journal, 2021, ⟨10.1007/s10719-021-10030-y⟩
Article dans une revue hal-03522622v1

Sulfatase 2 Modulates Fate Change from Motor Neurons to Oligodendrocyte Precursor Cells through Coordinated Regulation of Shh Signaling with Sulfatase 1

Wen Jiang , Yugo Ishino , Hirokazu Hashimoto , Kazuko Keino-Masu , Masayuki Masu , et al.
Developmental Neuroscience, 2017, Developmental Neuroscience, 39 (5), pp.361-374. ⟨10.1159/000464284⟩
Article dans une revue hal-03180563v1
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Contribution of Sulfated Glycosaminoglycans to the Pathology of Amyloidosis

Kazuchika Nishitsuji , Kenji Uchimura
trends in glycoscience and glycotechnology, 2021, trends in glycoscience and glycotechnology, 33 (196), pp.E141-E145. ⟨10.4052/tigg.2105.1e⟩
Article dans une revue hal-04008678v1

Edition of Heparan sulfate by human endosulfatases monitored by several analytical techniques

Nesrine El Omrani , Salomé Poyer , Cédric Przybylski , Yoshiko Takeda-Uchimura , Kenji Uchimura , et al.
IMMS 2023, Jul 2023, Paris, France
Poster de conférence hal-04429176v1
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GlcNAc6ST2/CHST4 Is Essential for the Synthesis of R-10G-Reactive Keratan Sulfate/Sulfated N-Acetyllactosamine Oligosaccharides in Mouse Pleural Mesothelium

Yoshiko Takeda-Uchimura , Midori Ikezaki , Tomoya O Akama , Yoshito Ihara , Fabrice Allain , et al.
Molecules, 2024, 29, ⟨10.3390/molecules29040764⟩
Article dans une revue hal-04479404v1

Sulfated glycosaminoglycans in protein aggregation diseases

Kazuchika Nishitsuji , Kenji Uchimura
Glycoconjugate Journal, 2017, Glycoconjugate journal, 34 (4), pp.453-466. ⟨10.1007/s10719-017-9769-4⟩
Article dans une revue hal-03285223v1

Growth Factor Midkine Promotes T-Cell Activation through Nuclear Factor of Activated T Cells Signaling and Th1 Cell Differentiation in Lupus Nephritis

Tomohiro Masuda , Kayaho Maeda , Waichi Sato , Tomoki Kosugi , Yuka Sato , et al.
The American journal of pathology, 2017, The American journal of pathology, 187 (4), pp.740-751. ⟨10.1016/j.ajpath.2016.12.006⟩
Article dans une revue hal-03172990v1

Correction of spherical aberration in multi-focal multiphoton microscopy with spatial light modulator

Naoya Matsumoto , Alu Konno , Yasushi Ohbayashi , Takashi Inoue , Akiyuki Matsumoto , et al.
Optics Express, 2017, Optics Express, 25 (6), pp.7055-7068. ⟨10.1364/OE.25.007055⟩
Article dans une revue hal-03174752v1

Deficiency of a sulfotransferase for sialic acid-modified glycans mitigates Alzheimer's pathology

Zui Zhang , Yoshiko Takeda-Uchimura , Tahmina Foyez , Shiori Ohtake-Niimi , Null Narentuya , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2017, Proceedings of the National Academy of Sciences of the United States of America, 114 (14), pp.E2947-E2954. ⟨10.1073/pnas.1615036114⟩
Article dans une revue hal-03180438v1
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Stepwise transmigration of T- and B cells through a perivascular channel in high endothelial venules

Kibaek Choe , Jieun Moon , Soo Yun Lee , Eunjoo Song , Ju Hee Back , et al.
Life Science Alliance, 2021, 4 (8), pp.e202101086. ⟨10.26508/lsa.202101086⟩
Article dans une revue hal-03439384v1
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Simultaneous targeting of primary tumor, draining lymph node, and distant metastases through high endothelial venule-targeted delivery

Liwei Jiang , Sungwook Jung , Jing Zhao , Vivek Kasinath , Takaharu Ichimura , et al.
Nano Today, 2021, 36, pp.101045. ⟨10.1016/j.nantod.2020.101045⟩
Article dans une revue hal-03445338v1