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Regions 1.2 and 3.2 of the RNA Polymerase σ Subunit Promote DNA Melting and Attenuate Action of the Antibiotic Lipiarmycin

Zakia Morichaud , Laurent Chaloin , Konstantin Brodolin
Journal of Molecular Biology, 2016, 428 (2), pp.463 - 476. ⟨10.1016/j.jmb.2015.12.017⟩
Article dans une revue hal-01868357v1
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Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization

Zakia Morichaud , Stefano Trapani , Rishi K Vishwakarma , Laurent Chaloin , Corinne Lionne , et al.
Nature Communications, 2023, 14 (1), pp.484. ⟨10.1038/s41467-023-36113-y⟩
Article dans une revue hal-04277431v1
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Resistance to rifampicin: at the crossroads between ecological, genomic and medical concerns

Audrey Tupin , Maxime Gualtieri , Françoise Roquet-Banères , Zakia Morichaud , Konstantin Brodolin , et al.
International Journal of Antimicrobial Agents, 2010, 35 (6), pp.519. ⟨10.1016/j.ijantimicag.2009.12.017⟩
Article dans une revue istex hal-00585816v1

In Xenopus egg extracts DNA replication initiates preferentially at or near asymmetric AT sequences.

S. Stanojcic , Jm Lemaitre , K. Brodolin , E. Danis , M. Mechali
Molecular and Cellular Biology, 2008, 28 (17), pp.5265-5274. ⟨10.1128/MCB.00181-08⟩
Article dans une revue hal-00322416v1

Differential melting of the transcription start site associated with changes in RNA polymerase-promoter contacts in initiating transcription complexes.

K. Brodolin , Malcolm Buckle
Journal of Molecular Biology, 2001, 307 (1), pp.25-30. ⟨10.1006/jmbi.2000.4483⟩
Article dans une revue istex hal-00277547v1

Region 1.2 of the RNA polymerase sigma subunit controls recognition of the -10 promoter element.

Nikolay Zenkin , Andrey Kulbachinskiy , Yuliya Yuzenkova , Arkady Mustaev , Irina Bass , et al.
EMBO Journal, 2007, 26 (4), pp.955-64. ⟨10.1038/sj.emboj.7601555⟩
Article dans une revue hal-00346460v1

The transcription inhibitor lipiarmycin blocks DNA fitting into the RNA polymerase catalytic site.

Audrey Tupin , Maxime Gualtieri , Jean-Paul Leonetti , Konstantin Brodolin
EMBO Journal, 2010, 29 (15), pp.2527-37. ⟨10.1038/emboj.2010.135⟩
Article dans une revue hal-00509067v1

HoxB domain induction silences DNA replication origins in the locus and specifies a single origin at its boundary.

Grégoire David , K. Brodolin , M. Mechali
EMBO Reports, 2006, 7, pp.812-816. ⟨10.1038/sj.embor.7400758⟩
Article dans une revue hal-00113404v1

Myxopyronin: a punch in the jaws of bacterial RNA polymerase.

Audrey Tupin , Maxime Gualtieri , Konstantin Brodolin , Jean-Paul Leonetti
Future Microbiology, 2009, 4 (2), pp.145-9. ⟨10.2217/17460913.4.2.145⟩
Article dans une revue hal-00378979v1

Resistance to rifampicin: at the crossroads between ecological, genomic and medical concerns.

Audrey Tupin , Maxime Gualtieri , Françoise Roquet-Banères , Zakia Morichaud , Konstantin Brodolin , et al.
International Journal of Antimicrobial Agents, 2010, 35 (6), pp.519-23. ⟨10.1016/j.ijantimicag.2009.12.017⟩
Article dans une revue istex hal-00509068v1
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SOLEIL shining on the solution-state structure of biomacromolecules by synchrotron X-ray footprinting at the metrology beamline

Anna Baud , Laure Aymé , Florence Gonnet , Isabelle Salard , Yann Gohon , et al.
Journal of Synchrotron Radiation, 2017, 24, pp.576-585. ⟨10.1107/S1600577517002478⟩
Article dans une revue hal-01608337v1
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RbpA relaxes promoter selectivity of M. tuberculosis RNA polymerase

Ayyappasamy Sudalaiyadum Perumal , Rishi kishore Vishwakarma , Yangbo Hu , Zakia Morichaud , Konstantin Brodolin
Nucleic Acids Research, 2018, 46 (19), pp.10106-10118. ⟨10.1093/nar/gky714⟩
Article dans une revue inserm-02137260v1
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Single-molecule analysis reveals the mechanism of transcription activation in M. tuberculosis

Rishi Kishore Vishwakarma , Anne-Marinette Cao , Zakia Morichaud , Ayyappasamy Sudalaiyadum Perumal , Emmanuel Margeat , et al.
Science Advances , 2018, 4 (5), pp.eaao5498. ⟨10.1126/sciadv.aao5498⟩
Article dans une revue hal-02346231v1

Frequency and characterisation of spontaneous lipiarmycin-resistant Enterococcus faecalis mutants selected in vitro.

Maxime Gualtieri , Audrey Tupin , Konstantin Brodolin , Jean-Paul Leonetti
International Journal of Antimicrobial Agents, 2009, epub ahead of print. ⟨10.1016/j.ijantimicag.2009.07.003⟩
Article dans une revue istex hal-00420540v1