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Crystal structures ofLymphocytic choriomeningitis virusendonuclease domain complexed with diketo-acid ligands
Magali Saez-Ayala
,
Elsie Yekwa
,
Mauro Carcelli
,
Bruno Canard
,
Karine Alvarez
,
et al.
Article dans une revue
hal-03078366v1
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Gln151 of HIV-1 reverse transcriptase acts as a steric gate towards clinically relevant acyclic phosphonate nucleotide analogues.
Antoine Frangeul
,
Cécile Bussetta
,
Jérôme Deval
,
Karine Barral
,
Karine Alvarez
,
et al.
Antiviral Therapy, 2019, 13 (1), pp.115-24
Article dans une revue
hal-02061712v1
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Synthesis and substrate properties towards HIV-1 reverse transcriptase of new diphosphate analogues of 9-[(2-phosphonomethoxy)ethyl]adenine
Wolfgang Hg Laux
,
Stephane Priet
,
Karine Alvarez
,
Suzanne Peyrottes
,
Christian Perigaud
Article dans une revue
hal-02094536v1
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Contribution to PNA-RNA Chimera Synthesis: One-Pot Microwave-Assisted Ugi Reaction to Obtain Dimeric Building Blocks
Reuben Ovadia
,
Clémence Mondielli
,
Jean-Jacques Vasseur
,
Carine Baraguey
,
Karine Alvarez
Article dans une revue
hal-02197216v1
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Synthesis and structural characterization of monomeric and dimeric peptide nucleic acids prepared by using microwave-promoted multicomponent reactions
Reuben Ovadia
,
Aurelien Lebrun
,
Ivan Barvik
,
Jean-Jacques Vasseur
,
Carine Baraguey
,
et al.
Article dans une revue
hal-01438999v1
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The pro-oligonucleotide approach: solid phase synthesis and preliminary evaluation of model pro-dodecathymidylates
J.J. Vasseur
,
Guilhem Tosquellas
,
Karine Alvarez
,
Christelle Dell'Aquila
,
François Morvan
,
et al.
Article dans une revue
hal-03008426v1
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Structural characterisation and inhibition of Arenavirus replication complex elements : assembly, function and inhibition of embedded nucleases
Sergio Hernández
,
Nicolas Papageorgiou
,
Maria Spiliopoulou
,
Mikael Feracci
,
Laura Garlatti
,
et al.
26TH CONGRESS AND GENERAL ASSEMBLY OF THE INTERNATIONAL UNION OF CRYSTALLOGRAPHY, Aug 2023, Melbourne (AUS), Australia
Poster de conférence
hal-04180334v1
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Novel 2-phenyl-5-[(E)-2-(thiophen-2-yl)ethenyl]-1,3,4-oxadiazole and 3-phenyl-5-[(E)-2-(thiophen-2-yl)ethenyl]-1,2,4-oxadiazole derivatives as dengue virus inhibitors targeting NS5 polymerase
Fatiha Benmansour
,
Cecilia Eydoux
,
Gilles Querat
,
Xavier de Lamballerie
,
Bruno Canard
,
et al.
Article dans une revue
hal-02061730v1
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Efficient access to 3′-deoxy-3′-(4-substituted-1,2,3-triazol-1-yl)-thymidine derivatives via ligand-promoted CuAAC
Laura Garlatti
,
Raphaël Huet
,
Karine Alvarez
Article dans une revue
hal-03457261v1
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Remdesivir and SARS-CoV-2: Structural requirements at both nsp12 RdRp and nsp14 Exonuclease active-sites
Ashleigh Shannon
,
Nhung Thi-Tuyet Le
,
Barbara Selisko
,
Cecilia Eydoux
,
Karine Alvarez
,
et al.
Article dans une revue
hal-03052253v1
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Arenaviridae NP-exonuclease inhibition by bisphosphonate
Thi Hong van Nguyen
,
Elsie Yekwa
,
Barbara Selisko
,
Bruno Canard
,
Karine Alvarez
,
et al.
Article dans une revue
hal-03663359v1
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Protein-primed RNA synthesis in SARS-CoVs and structural basis for inhibition by AT-527
Ashleigh Shannon
,
Véronique Fattorini
,
Bhawna Sama
,
Barbara Selisko
,
Mikael Feracci
,
et al.
2021
Pré-publication, Document de travail
hal-03367971v1
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AT-752 targets multiple sites and activities on the Dengue virus replication enzyme NS5
Mikael Feracci
,
Cécilia Eydoux
,
Véronique Fattorini
,
Lea Lo Bello
,
Pierre Gauffre
,
et al.
Article dans une revue
hal-04159074v1
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Identification of a new natural gastric lipase inhibitor from star anise
Jannet Kamoun
,
Renaud Rahier
,
Mohamed Sellami
,
Imed Koubaa
,
Pascal Mansuelle
,
et al.
Article dans une revue
hal-03006544v1
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A high-throughput fluorescence polarization assay to discover inhibitors of arenavirus and coronavirus exoribonucleases
Sergio Hernández
,
Mikael Feracci
,
Carolina Trajano de Jesus
,
Priscila El-Kazzi
,
Rafik Kaci
,
et al.
2022
Pré-publication, Document de travail
hal-03660938v1
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Preparation of purine and pyrimidine acyclic nucleotide analogs as antiviral agents
Karine Barral
,
Bruno Canard
,
Karine Alvarez
,
Jean-Louis Romette
,
Johan Neyts
,
et al.
France, Patent n° : WO 2007-IB4233. 2007
Brevet
hal-02063281v1
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A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase
Ashleigh Shannon
,
Véronique Fattorini
,
Bhawna Sama
,
Barbara Selisko
,
Mikael Feracci
,
et al.
Article dans une revue
hal-03572811v1
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Observation of arenavirus nucleoprotein heptamer assembly
Nicolas Papageorgiou
,
Afroditi Vaitsopoulou
,
Awa Diop
,
Thi Hong van Nguyen
,
Bruno Canard
,
et al.
Article dans une revue
hal-03143071v1
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Metal chelators for the inhibition of the lymphocytic choriomeningitis virus endonuclease domain
Magali Saez-Ayala
,
Elsie Laban Yekwa
,
Clémence Mondielli
,
Loic Roux
,
Sergio Hernández
,
et al.
Article dans une revue
hal-03076409v1
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Discovery, SAR study and ADME properties of methyl 4-amino-3-cyano-1-(2-benzyloxyphenyl)-1 H -pyrazole-5-carboxylate as an HIV-1 replication inhibitor
Jeanne Fichez
,
Cathia Soulié
,
Laurent Le Corre
,
Sophie Sayon
,
Stéphane Priet
,
et al.
Article dans une revue
hal-03030936v1
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Acyclic nucleoside thiophosphonates as potent inhibitors of HIV and HBV replication
Karine Barral
,
Clément Weck
,
Nadine Payrot
,
Loic Roux
,
Céline Durafour
,
et al.
Article dans une revue
hal-02061721v1
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Enzymatic synthesis of acyclic nucleoside thiophosphonate diphosphates: Effect of the alpha-phosphorus configuration on HIV-1 RT activity
Stephane Priet
,
Loic Roux
,
Magali Saez-Ayala
,
Francois Ferron
,
Bruno Canard
,
et al.
Article dans une revue
hal-01439000v1
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Crystal Structure of E. coli Alcohol Dehydrogenase YqhD: Evidence of a Covalently Modified NADP Coenzyme
Gerlind Sulzenbacher
,
Karine Alvarez
,
Robert H H van den Heuvel
,
Cees Versluis
,
Silvia Spinelli
,
et al.
Article dans une revue
istex
hal-03160576v1
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Identification of potent inhibitors of arenavirus and SARS-CoV-2 exoribonucleases by fluorescence polarization assay
Sergio Hernández
,
Mikael Feracci
,
Carolina Trajano de Jesus
,
Priscila El Kazzi
,
Rafik Kaci
,
et al.
Article dans une revue
hal-03860671v1
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3'-Deoxy phosphoramidate dinucleosides as improved inhibitors of Hepatitis C virus subgenomic replicon and NS5B polymerase activity.
Stephane Priet
,
Ivan Zlatev
,
Ivan Barvik
,
Katrien Geerts
,
Pieter Leyssen
,
et al.
Article dans une revue
hal-00533933v1
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Preparation of thiophenepropenamide derivatives as flavivirus inhibitors in treatment of viral infections
Karine Barral
,
Jean Claude Guillemot
,
Bruno Canard
,
Gilles Quérat
,
Karine Alvarez
,
et al.
France, Patent n° : WO 2017102014. 2017
Brevet
hal-02063286v1
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Identification of allosteric inhibitors blocking the hepatitis C virus polymerase NS5B in the RNA synthesis initiation step.
Stéphane Betzi
,
Cécilia Eydoux
,
Cécile Bussetta
,
Marilyne Blemont
,
Pieter Leyssen
,
et al.
Article dans une revue
istex
hal-00418783v1
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Synthesis, in Vitro Antiviral Evaluation, and Stability Studies of Novel α-Borano-Nucleotide Analogues of 9-[2-(Phosphonomethoxy)ethyl]adenine and ( R )-9-[2-(Phosphonomethoxy)propyl]adenine
Karine Barral
,
Stephane Priet
,
Joséphine Sire
,
Johan Neyts
,
Jan Balzarini
,
et al.
Article dans une revue
istex
hal-02061667v1
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A high-throughput fluorescence polarization assay to discover inhibitors of arenavirus and coronavirus exoribonucleases
Sergio Hernández
,
Mikael Feracci
,
Carolina Trajano de Jesus
,
Priscila El-Kazzi
,
Rafik Kaci
,
et al.
2021
Pré-publication, Document de travail
hal-03411674v1
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Validation of an Image Analysis Method for the Determination of the Parasitemia in Malaria-Infected Erythrocyte Cultures
German Gonzalez
,
Karine Alvarez
,
Mirko Zimic
,
Stephane Bertani
,
Michel Sauvain
,
et al.
Journées du Consortium Antiparasitaire CaP2012, Feb 2012, Toulouse, France
Poster de conférence
hal-03573430v1
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