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A stereocontrolled synthesis of the hydrophobic moiety of rhamnolipids
Boudjema Menhour
,
Patrick Mayon
,
Karen Plé
,
Sandrine Bouquillon
,
Stephan Dorey
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et al.
Article dans une revue
hal-02540463v1
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Neurofibromatosis type I: from basic to applied research
Béatrice Vallée
,
A. Cosson
,
M. Doudeau
,
F Godin
,
A. Braka
,
et al.
4th LIA Workshop, Jun 2017, Cracovie, Poland
Communication dans un congrès
hal-02928517v1
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Polyphenol purification by solid support free liquid liquid chromatography
Jean-Hugues Renault
,
Kishan Gopal Ramawat
,
Jean-Michel Mérillon
,
Jane Hubert
,
Karen Plé
,
et al.
K.G. Ramawat; J.M. Mérillon; M. Henry. Natural Products - Phytochemistry, Botany, Metabolism, XLII, Springer Berlin Heidelberg, 2013, 978-3-642-22144-6
Chapitre d'ouvrage
hal-01968738v1
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Structure activity relationships of some hederagenin diglycosides : haemolysis, cytotoxicity and apoptosis induction
Martin Chwalek
,
Nathalie Lalun
,
Hélène Bobichon
,
Karen Plé
,
Laurence Voutquenne
BBA - Biochimica et Biophysica Acta, 2006, 1760, pp.1418-1427
Article dans une revue
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Projet Région LiCorNe: LIMK protein inhibitors, new therapeutic agents for treatment of cognitive disorders associated with type I Neurofibromatosis
Béatrice Vallée
,
Michel Doudeau
,
F. Godin
,
H. Cubéros
,
A. Champiré
,
et al.
Journée Fédération PCV FR2708, Jan 2016, Orléans, France
Poster de conférence
hal-02924056v1
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Synthesis of l-arabinopyranose containing hederagenin saponins
Karen Plé
,
Martin Chwalek
,
Laurence Voutquenne-Nazabadioko
Tetrahedron, 2005, 61 (18), pp.4347-4362
Article dans une revue
hal-01996917v1
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Synthesis ofα-Hederin,δ-Hederin, and Related Triterpenoid Saponins
Karen Plé
,
Martin Chwalek
,
Laurence Voutquenne-Nazabadioko
Article dans une revue
istex
hal-01996941v1
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4-(7H-Pyrrolo[2,3-D]pyrimidin-4-yl)-3,6-dihydropyridine-(2H)-carboxamide derivatives as Limk and/or Rock kinases inhibitors for use in the treatment of cancer
Sylvain Routier
,
Hélène Bénédetti
,
Béatrice Vallée
,
Pascal Bonnet
,
Karen Plé
,
et al.
France, Patent n° : WO2021239727 A1. BCT. 2021
Brevet
hal-03555349v1
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LIM kinases, promising but reluctant therapeutic targets: chemistry and preclinical validation in vivo
Rayan Berabez
,
Sylvain Routier
,
Hélène Bénédetti
,
Karen Plé
,
Béatrice Vallée
Article dans une revue
hal-03721458v1
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Développement de petites molécules inhibitrices des LIM kinases, nouvelles cibles thérapeutiques pour lutter contre le cancer, les maladies neurologiques et la neurofibromatose
Béatrice Vallée
,
Karen Plé
,
A. Cosson
,
M. Doudeau
,
F. Godin
,
et al.
Journée Fédération CBM-ICOA, Jan 2018, Orléans, France
Communication dans un congrès
hal-02928530v1
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Gold(I)-Catalyzed Intramolecular Hydroamination and Hydroalkoxylation of Alkynes: Access to Original Heterospirocycles
Kossi Efouako Soklou
,
Hamid Marzag
,
Jean-Philippe Bouillon
,
Mathieu Marchivie
,
Sylvain Routier
,
et al.
Article dans une revue
hal-02916186v1
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Convenient Syntheses of isomaltose derivatives from amygdalin
Karen Plé
,
Martin Chwalek
Tetrahedron Letters, 2004, pp.4749-4753
Article dans une revue
hal-00134107v1
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Proposal of a Set of Model Polymer Additives Designed for Confocal FRAP Diffusion Experiments
Jérémy Pinte
,
Catherine Joly
,
Karen Plé
,
Patrice Dole
,
Alexandre Feigenbaum
Article dans une revue
istex
hal-02659598v1
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Conception, synthèse et évaluation biologique d’inhibiteurs de LIM kinases
A. Champiré
,
A. Braka
,
Béatrice Vallée
,
M. Doudeau
,
F. Godin
,
et al.
29e colloque de Biotechnocentre, Oct 2016, Seillac, France
Poster de conférence
hal-02904847v1
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Synthesis of Heterospirocycles through Gold‐(I) Catalysis, Useful Building Blocks for Medicinal Chemistry
Kossi Efouako Soklou
,
Hamid Marzag
,
Béatrice Vallée
,
Sylvain Routier
,
Karen Plé
Article dans une revue
hal-03411162v1
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Development of small molecule inhibitors of LIM kinases, new therapeutic targets to treat Neurofibromatosis type I
Béatrice Vallée
,
A. Cosson
,
M. Doudeau
,
F. Godin
,
A. Champiré
,
et al.
Joint Global Neurofibromatosis Conference 2018, Nov 2018, Paris, France
Poster de conférence
hal-02924077v1
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Perinatal Exposure to the Cyanotoxin β-N-Méthylamino-l-Alanine (BMAA) Results in Long-Lasting Behavioral Changes in Offspring—Potential Involvement of DNA Damage and Oxidative Stress
Anthony Laugeray
,
Asma Oummadi
,
Clément Jourdain
,
Justyne Feat
,
Géraldine Meyer-Dilhet
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et al.
Article dans une revue
hal-02447420v1
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Controlled Dimroth Rearrangement in the Suzuki-Miyaura Cross Coupling of Triazolopyridopyrimidines.
Anthony Champiré
,
Christine Vala
,
Achraf Laabid
,
Ahmed Benharref
,
Mathieu Marchivie
,
et al.
Article dans une revue
hal-01432873v1
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LIM Kinases: new anticancer therapeutic targets
Béatrice Vallée
,
A. Cosson
,
M. Doudeau
,
F. Godin
,
Anthony Champiré
,
et al.
Breast Cancer Symposium, Jun 2017, Nantes, France
Poster de conférence
hal-03680148v1
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LIM kinases, new therapeutic targets to treat cancers, neurological disorders and Neurofibromatosis: development of small molecule inhibitors
Béatrice Vallée
,
A. Cosson
,
M. Doudeau
,
F. Godin
,
A. Champiré
,
et al.
FEBS Meeting 2019, Jul 2019, Cracovie, Poland
Poster de conférence
hal-02924140v1
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Drawing Mononuclear Octahedral Coordination Compounds Containing Tridentate Chelating Ligands
Aminou Mohamadou
,
Karen Plé
,
Arnaud Haudrechy
Article dans une revue
hal-01889386v1
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Structure–activity relationships of some hederagenin diglycosides: Haemolysis, cytotoxicity and apoptosis induction
Martin Chwalek
,
Nathalie Lalun
,
Hélène Bobichon
,
Karen Plé
,
Laurence Voutquenne-Nazabadioko
Article dans une revue
hal-01996864v1
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30th Franco-Belgian conference of pharmacochemistry
Charlotte Bouckaert
,
Eric Goffin
,
Sebastien Dilly
,
Julien Hanson
,
Lionel Pochet
,
et al.
Article dans une revue
hal-02141338v1
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Development of a bioactive fluorescent inhibitor probe targeting the Rho kinase ROCK for monitoring inhibition action
Justine Corret
,
Sokaina Hammoud
,
Frédéric Buron
,
Pierre Daligaux
,
Christophe Chesné
,
et al.
FEBS 2021, the 45th FEBS Congress, Jul 2021, Lnubljana, virtual, Slovenia
Poster de conférence
hal-03679980v1
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Recycling Mitsunobu coupling: a shortcut for troublesome esterifications
Boudjema Menhour
,
Firmin Obounou Akong
,
Patrick Mayon
,
Karen Plé
,
Sandrine Bouquillon
,
et al.
Article dans une revue
hal-01831189v1
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LIM kinases as new therapeutic targets for the treatment of neurofibromatosis type 1
A. Champiré
,
A. Braka
,
B. Vallée
,
M. Doudeau
,
F. Godin
,
et al.
VII International Symposium on Advances in Synthetic and Medicinal Chemistry (EFMC) –, Aug 2017, Vienne, Austria
Poster de conférence
hal-02904794v1
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Probe drug T-1032 N-oxygenation mediated by cytochrome P450 3A5 in human hepatocytes in vitro and in humanized-liver mice in vivo
Shotaro Uehara
,
Makiko Shimizu
,
Karen Plé
,
Sylvain Routier
,
Nao Yoneda
,
et al.
Article dans une revue
hal-03721472v1
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Détermination et mise en œuvre d’un modèle in vivo pour tester de nouveaux inhibiteurs originaux des LIM kinases, cibles thérapeutiques émergentes dans le cancer
Béatrice Vallée
,
K. Plé
,
A. Cosson
,
M. Doudeau
,
F. Godin
,
et al.
Cancéropôle Grand Ouest, Colloque du Réseau Molécules marines, métabolisme et cancer, May 2019, Mansigné, France
Communication dans un congrès
hal-02928507v1
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LIM kinases: new therapeutic targets to treat Neurofibromatosis type I
Béatrice Vallée
,
Michel Doudeau
,
Fabienne Godin
,
Anthony Champiré
,
Karen Plé
,
et al.
The 7th EMBO meeting, Sep 2016, Mannheim, Germany.
Poster de conférence
hal-02453490v1
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New perspectives for microbial glycolipid fractionation and purification processes
Jane Hubert
,
Karen Plé
,
Mahmoud Hamzaoui
,
Gladys Nuissier
,
Imane Hadef
,
et al.
Comptes Rendus. Chimie, 2012, 15 (1), pp.18-28
Article dans une revue
hal-01968714v1
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