mon CV

Kévin Gillois, Charlotte Stoffels, Mathilde Leveque, Isabelle Fourquaux, Justine Blesson, et al.. Repeated exposure of Caco-2 versus Caco-2/HT29-MTX intestinal cell models to (nano)silver in vitro: Comparison of two commercially available colloidal silver products. Science of the Total Environment, Elsevier, 2021, 754, ⟨10.1016/j.scitotenv.2020.142324⟩. ⟨hal-02945727⟩

Benoît Pons, Nicolas Loiseau, Saleha Hashim, Soraya Tadrist, Gladys Mirey, et al.. Functional Study of Haemophilus ducreyi Cytolethal Distending Toxin Subunit B. Toxins, MDPI, 2020, 12 (9), pp.530. ⟨10.3390/toxins12090530⟩. ⟨hal-02927138⟩

Thierry Gauthier, Carolina Duarte-Hospital, Julien Vignard, Elisa Boutet-Robinet, Michael Sulyok, et al.. Versicolorin A, a precursor in aflatoxins biosynthesis, is a food contaminant toxic for human intestinal cells. Environment International, Elsevier, 2020, 137, 15 p. ⟨10.1016/j.envint.2020.105568⟩. ⟨hal-02556860⟩

Alan D'andrea, Emilie Dubois, Laure Guitton-Sert, Mariline Béliveau, Kalindi Parmar, et al.. A Fanci knockout mouse model reveals common and distinct functions for FANCI and FANCD2. Nucleic Acids Research, Oxford University Press, 2019, 47 (14), pp.7532-7547. ⟨10.1093/nar/gkz514⟩. ⟨hal-02915101⟩

Anne Fernandez Vidal, Liana C. Arnaud, Manon Maumus, Marianne Chevalier, Gladys Mirey, et al.. Exposure to the fungicide captan induces DNA base alterations and replicative stress in mammalian cells. Environmental and Molecular Mutagenesis, Wiley-Blackwell, 2019, 60 (3), pp.286-297. ⟨10.1002/em.22268⟩. ⟨hal-02620276⟩

Benoît J. Pons, Julien Vignard, Gladys Mirey. Cytolethal distending toxin subunit B: A review of structure–function relationship. Toxins, MDPI, 2019, 11 (10), 20 p. ⟨10.3390/toxins11100595⟩. ⟨hal-02618477⟩

Zhen He, Raad Z. Gharaibeh, Rachel C. Newsome, Jllian L. Pope, Michael W. Dougherty, et al.. Campylobacter jejuni promotes colorectal tumorigenesis through the action of cytolethal distending toxin. Gut, BMJ Publishing Group, 2019, 68 (2), pp.289-300. ⟨10.1136/gutjnl-2018-317200⟩. ⟨hal-02627995⟩

Benoît Pons, Elisabeth Bezine, Mélissa Hanique, Valerie Guillet, Lionel Mourey, et al.. Cell transfection of purified cytolethal distending toxin B subunits allows comparing their nuclease activity while plasmid degradation assay does not. PLoS ONE, Public Library of Science, 2019, 14 (3), pp.e0214313. ⟨10.1371/journal.pone.0214313⟩. ⟨hal-02346660⟩

Benjamin Kopp, Julien Vignard, G. Mirey, Valérie Fessard, Daniel Zalko, et al.. Genotoxicity and mutagenicity assessment of food contaminant mixtures present in the French diet. Environmental and Molecular Mutagenesis, Wiley-Blackwell, 2018, 59 (8), pp.1-13. ⟨10.1002/em.22214⟩. ⟨anses-01880114⟩

Vanessa Graillot, Thibault Metenier, Odile Mondésert, Julien Vignard, Valérie Lobjois, et al.. Use of a reliable metabolically competent human rghep(+) hepatocyte model engineered with biological tracers for in vitro micronucleus test associating high-content imaging. Drug Metabolism and Pharmacokinetics, Japanese Society for the Study of Xenobiotics, 2018, 33 (1), pp.S59. ⟨10.1016/j.dmpk.2017.11.200⟩. ⟨hal-02618768⟩

Nadège Bossuet-Greif, Julien Vignard, Frederic Taieb, Gladys Mirey, Damien Dubois, et al.. The colibactin genotoxin generates DNA interstrand cross-links in infected cells. mBio, American Society for Microbiology, 2018, 9 (2), pp.e02393-17. ⟨10.1128/mBio.02393-17⟩. ⟨hal-02627565⟩

Anne Fernandez Vidal, Julien Vignard, Gladys Mirey. Around and beyond 53BP1 nuclear bodies. International Journal of Molecular Sciences, MDPI, 2017, 18 (12), ⟨10.3390/ijms18122611⟩. ⟨hal-02619788⟩

Marie Liamin, Elisa Boutet-Robinet, Emilien L. Jamin, Morgane Fernier, Laure Khoury, et al.. Benzo[a]pyrene-induced DNA damage associated with mutagenesis in primary human activated T lymphocytes. Biochemical Pharmacology, Elsevier, 2017, 137, pp.113-124. ⟨10.1016/j.bcp.2017.04.025⟩. ⟨hal-01560145⟩

Denis Jullien, Julien Vignard, Yoann Fedor, Nicolas Béry, Aurélien Olichon, et al.. Chromatibody, a novel non-invasive molecular tool to explore and manipulate chromatin in living cells. Development (Cambridge, England), Company of Biologists, 2016, 143 (14), ⟨10.1242/dev.141804⟩. ⟨hal-01602858⟩

Vanessa Graillot, Inge Dormoy, Jacques Dupuy, Jerry W. Shay, Laurence Huc, et al.. Genotoxicity of cytolethal distending toxin (cdt) on isogenic human colorectal cell lines: potential promoting effects for colorectal carcinogenesis. Frontiers in Cellular and Infection Microbiology, Frontiers, 2016, 6, pp.1-13. ⟨10.3389/fcimb.2016.00034⟩. ⟨hal-02635460⟩

Elisabeth Bezine, Yann Malaisé, Aurore Loeuillet, Marianne Chevalier, Elisa Boutet-Robinet, et al.. Cell resistance to the cytolethal distending toxin involves an association of DNA repair mechanisms. Scientific Reports, Nature Publishing Group, 2016, 6, pp.1-15. ⟨10.1038/srep36022⟩. ⟨hal-01602345⟩

Vanessa Graillot, Odile Mondesert, Thibault Metenier, Julien Vignard, Valerie Lobjois, et al.. A new in vitro micronucleus test in living cells associating biological tracers and high-content imaging. Toxicology Letters, Elsevier, 2016, 258, pp.S146. ⟨10.1016/j.toxlet.2016.06.1566⟩. ⟨hal-01602870⟩

Denis Jullien, Julien Vignard, Yoann Fedor, Nicolas Béry, Aurélien Olichon, et al.. Chromatibody, a novel non-invasive molecular tool to explore and manipulate chromatin in living cells. Journal of Cell Science, Company of Biologists, 2016, 129 (13), pp.2673-2683. ⟨10.1242/jcs.183103⟩. ⟨hal-01602848⟩

Elisabeth Bezine, Julien Vignard, Gladys Mirey. The cytolethal distending toxin effects on Mammalian cells: a DNA damage perspective.. Cells, MDPI, 2014, 3 (2), pp.592-615. ⟨10.3390/cells3020592⟩. ⟨hal-01192559⟩

Yoann Fedor, Julien Vignard, Marie-Laure Travers, Elisa Boutet-Robinet, Claude Watrin, et al.. From single-strand breaks to double-strand breaks during S-phase: a new mode of action of the Escherichia coli Cytolethal Distending Toxin. Cellular Microbiology, Wiley, 2013, 15 (1), pp.1 - 15. ⟨10.1111/cmi.12028⟩. ⟨hal-02647902⟩

Julien Vignard, Gladys Mirey, Bernard Salles. Ionizing-radiation induced DNA double-strand breaks: a direct and indirect lighting up. Radiotherapy and Oncology, Elsevier, 2013, 108 (3), pp.362-369. ⟨10.1016/j.radonc.2013.06.013⟩. ⟨hal-02648277⟩

Jana Krietsch, Marie Christine Caron, Jean-Philippe Gagné, Chantal Ethier, Julien Vignard, et al.. PARP activation regulates the RNA-binding protein NONO in the DNA damage response to DNA double-strand breaks. Nucleic Acids Research, Oxford University Press, 2012, 40 (20), pp.10287-301. ⟨10.1093/nar/gks798⟩. ⟨hal-01137043⟩

Nicolas Macaisne, Julien Vignard, Raphaël Mercier. SHOC1 and PTD form an XPF-ERCC1-like complexthat is required for formation of class I crossovers. Journal of Cell Science, Company of Biologists, 2011, 124 (Pt 16), pp.2687-2691. ⟨10.1242/jcs.088229⟩. ⟨hal-01000742⟩

Julien Vignard, C. Charbonnel, Jean-Yves Masson. Partners apart: Smc6-independent DNA binding activity of Smc5 on single-strand DNA. Cell Cycle, Taylor & Francis, 2011, 10 (7), pp.1025-1026. ⟨10.4161/cc.10.7.15212⟩. ⟨hal-02643095⟩

François Roudier, Lionel Gissot, Frédéric Beaudoin, Richard Haslam, Louise Michaelson, et al.. Very-long-chain fatty acids are involved in polar auxin transport and developmental patterning in Arabidopsis.. The Plant cell, American Society of Plant Biologists (ASPB), 2010, 22 (2), pp.364-75. ⟨10.1105/tpc.109.071209⟩. ⟨hal-00856101⟩

Céline Roques, Yan Coulombe, Mathieu Delannoy, Julien Vignard, Simona Grossi, et al.. MRE11–RAD50–NBS1 is a critical regulator of FANCD2 stability and function during DNA double-strand break repair. EMBO Journal, EMBO Press, 2009, 28 (16), pp.2400-2413. ⟨10.1038/emboj.2009.193⟩. ⟨hal-02662125⟩

Ramachander V. N. Turaga, Eric R. Paquet, Mari Sild, Julien Vignard, Chantal Garand, et al.. The Werner syndrome protein affects the expression of genes involved in adipogenesis and inflammation in addition to cell cycle and DNA damage responses.. Cell Cycle, Taylor & Francis, 2009, 8 (13), pp.2080-2092. ⟨10.4161/cc.8.13.8925⟩. ⟨hal-02655604⟩

James D. Higgins, Julien Vignard, Raphaël Mercier, Alice G. Pugh, F. Chris H. Franklin, et al.. AtMSH5 partners AtMSH4 in the class I meiotic crossover pathway in Arabidopsis thaliana, but is not required for synapsis. Plant Journal, Wiley, 2008, 55 (1), pp.28-39. ⟨10.1111/j.1365-313X.2008.03470.x⟩. ⟨hal-02661925⟩

Raphaël Mercier, Sylvie Jolivet, Julien Vignard, Stéphanie Durand, Jan Drouaud, et al.. Outcrossing as an explanation of the apparent unconventional genetic behavior of Arabidopsis thaliana hth mutants. Genetics, Genetics Society of America, 2008, 180 (4), pp.2295-2297. ⟨10.1534/genetics.108.095208⟩. ⟨hal-02656582⟩

Christine Mézard, Julien Vignard, Jan Drouaud, Raphaël Mercier. The road to crossovers: plants have their say. Trends in Genetics, Elsevier, 2007, 23 (2), pp.91-99. ⟨10.1016/j.tig.2006.12.007⟩. ⟨hal-02668854⟩

Julien Vignard, Tanja Siwiec, Liudmila Chelysheva, Nathalie Vrielynck, Florine Gonord, et al.. The interplay of RecA-related proteins and the MND1-HOP2 complex during meiosis in Arabidopsis thaliana. PLoS Genetics, Public Library of Science, 2007, 3 (10), pp.1894-906. ⟨10.1371/journal.pgen.0030176⟩. ⟨hal-02661109⟩

C. Kerzendorfer, Julien Vignard, A. Pedrosa-Harand, T. Siwiec, S. Akimcheva, et al.. The Arabidopsis thaliana MND1 homologue plays a key role in meiotic homologous pairing, synapsis and recombination. Journal of Cell Science, Company of Biologists, 2006, 119 (12), pp.2486-2496. ⟨10.1242/jcs.02967⟩. ⟨hal-02664509⟩

François Roudier, Lionel Gissot, Julien Vignard, Christine Rochat, P. Moreau, et al.. Alterations in sphingolipid synthesis in the model plant Arabidopsis thaliana is associated with cell polarity and developmental defects. Chemistry and Physics of Lipids, Elsevier, 2006, 143 (1-2), pp.100. ⟨hal-02657873⟩

Denis Jullien, Julien Vignard, Bernard Salles, Gladys Mirey. Anticorps monocaténaire à chaîne lourde de camelidae dirigé contre la chromatine et utilisations. 2013. ⟨hal-02807167⟩

Elisabeth Bezine, Julien Vignard, Gladys Mirey. The effect of Cytolethal Distending Toxin from Gram-negative bacteria on mammalian cells.. Prokaryotes: Physiology, Biochemistry and Cell Behavior., Nova science, 2014. ⟨hal-02792518⟩

Gladys Mirey, Vanessa Graillot, Odile Mondésert, Thibault Metenier, Julien Vignard, et al.. In vitro micronucleus test in living cells associating biological tracers and high-content imaging. 53. Congress of the European-Societies-of-Toxicology (EUROTOX), Sep 2017, Bratislava, Slovakia. pp.1, ⟨10.1016/j.toxlet.2017.08.072⟩. ⟨hal-02735959⟩

Elisabeth Bezine, Julien Vignard, Yann Malaisé, Aurore Loeuillet, Elisa Boutet-Robinet, et al.. L’analyse des voies de réparation nous renseigne sur les dommages à l’ADN induits par la toxine CDT. Journée des doctorants de l'INRA Toxalim, Jun 2015, Toulouse, France. ⟨hal-02800134⟩

Elisabeth Bezine, Julien Vignard, Marianne Chevalier, Elisa Boutet-Robinet, Bernard Salles, et al.. The bacterial cytolethal distending Toxin induces indirect double-strand breaks into eukaryotic cells. Journée de l’ecole Doctorale SEVAB, Mar 2015, Toulouse, France. ⟨hal-02796083⟩

Denis Jullien, Julien Vignard, Yoann Fedor, Aurélien Olichon, Michèle Crozatier, et al.. Nanobody-based universal histone binding domains for chromatin imaging and editing. 4. Biosensor Meeting of the Biosensor Group of the GDR 2588 Microscopie et Imagerie du Vivant, May 2014, Bordeaux, France. ⟨hal-02793548⟩

Denis Jullien, Julien Vignard, Yoann Fedor, Aurélien Olichon, Bernard Salles, et al.. VHH-based universal histone binding domains: novel tools for a different look on and manipulation of chromatin. FEBS EMBO 2014 Conférence, Aug 2014, Paris, France. 823 p. ⟨hal-02741249⟩

Elisabeth Bezine, Yoann Fedor, Julien Vignard, Elisa Boutet-Robinet, Bernard Salles, et al.. Genotoxicity and repair: the cytolethal distending toxin model. 4? workshop "Genome, Structure and Functions", Hôpital Rangueil. FRA., Apr 2013, Toulouse, France. ⟨hal-02809832⟩

Denis Jullien, Julien Vignard, Gladys Mirey, Bernard Ducommun. Développement de nouveaux outils de détection non-invasive des cassures double brin de l’ADN. Réunion du groupe Biosenseur GDR2588, Groupe Biosenseur GDR2588., Mar 2012, Montpellier, France. ⟨hal-02807599⟩

Julien Vignard, Benoît Pons, Anne Fernandez Vidal, Gladys Mirey. Cytolethal Distending Toxin (CDT) exhibits a unique ability to induce micronucleus in infected cells: possible implications regarding activation of the inflammatory response. DINGO, Jun 2018, Paris, France. 2018. ⟨hal-02790628⟩

Benoît Pons, Julien Vignard, Elisabeth Bezine, Jean-Sébastien Dupuy, Saleha Hashim, et al.. Cellular study of a bacterial DNA-damaging virulence factor, the Cytolethal Distending Toxin. EuroScience Open Forum, Jul 2018, Toulouse, France. 2018. ⟨hal-02789185⟩

Benoît Pons, Julien Vignard, Elisabeth Bezine, Saleha Hashim, Valérie Lobjois, et al.. Cellular study of a bacterial DNA-damaging virulence factor, the cytolethal distending toxin. Young Life Scientists’ Symposium on Genome Integrity, Nov 2018, Montpellier, France. 2018. ⟨hal-02787088⟩

Julien Vignard, Elisabeth Bezine, Gladys Mirey, Bernard Salles, Elisa Boutet-Robinet, et al.. Overview of the DNA repair pathways involved in the response to the cytolethal distending toxin. 11th 3R Meeting, May 2015, Presqu'île de Giens, France. pp.1, 2015. ⟨hal-02793078⟩

Elisabeth Bezine, Julien Vignard, Marianne Chevalier, Elisa Boutet-Robinet, Bernard Salles, et al.. Overview of the DNA repair pathways involved in response to the cytolethal distending toxin. The 6th EMBO Meeting, Sep 2015, Birmingham, United Kingdom. 2015. ⟨hal-02740247⟩

Elisabeth Bezine, Yoann Fedor, Julien Vignard, Elisa Boutet-Robinet, Bernard Salles, et al.. The bacterial cytolethal distending toxin: a nuclease inducing indirect DNA double-strand breaks into eukaryotic cells. FEBS EMBO 2014 Conférence, Aug 2014, Paris, France. 2014. ⟨hal-02740249⟩

Elisabeth Bezine, Yoann Fedor, Julien Vignard, Elisa Boutet-Robinet, Bernard Salles, et al.. A new mode of action of a bacterial genotoxin: the cytolethal distending toxin. Journée Ecole Doctorale SEVAB, Nov 2013, Toulouse, France. 2013. ⟨hal-02806633⟩

Elisabeth Bezine, Yoann Fedor, Julien Vignard, Elisa Boutet-Robinet, Bernard Salles, et al.. A new mode of action for the cytolethal distending toxin. 5. EMBO Meeting, Sep 2013, Amsterdam, Netherlands. 2013. ⟨hal-02748175⟩

Elisabeth Bezine, Yoann Fedor, Julien Vignard, Elisa Boutet-Robinet, Bernard Salles, et al.. Effets génotoxiques de la cytolethal distending toxin et mécanismes de signalisations. Journées des Microbiologistes de l’INRA 2012, Nov 2012, Avignon, France. 2012. ⟨hal-02746646⟩