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Rôles du calcium et des transports ioniques de l'épithélium des voies aériennes dans la réponse à l'agression septique par Pseudomonas aeruginosa.

 Julien Buyck
Physiologie [q-bio.TO]. Université du Droit et de la Santé - Lille II, 2008. Français. ⟨NNT : ⟩
Thèse tel-00386909v1

In Vitro Models for the Study of the Intracellular Activity of Antibiotics

 Julien Buyck , Sandrine Lemaire , Cristina Seral , Ahalieyah Anantharajah , Frédéric Peyrusson , et al.
Methods in molecular biology, pp.147-157, 2016, ⟨10.1007/978-1-4939-2854-5_13⟩
Chapitre d'ouvrage hal-02490448v1

Concentration dependent effect of amoxicillin against clinical strains of Helicobacter pylori

 Zahyra Kaouah , Julien Buyck , Sandrine Marchand , Christophe Burucoa , Maxime Pichon , et al.
30ème Réunion du Groupe d'Études Français des Helicobacter (GEFH), Jun 2023, Lille, France
Communication dans un congrès hal-04142680v1

A New Pharmacokinetic-Pharmacodynamic Model To Characterize the Inoculum Effect of Acinetobacter baumannii on Polymyxin B In Vitro

 Grace Akrong , Alexia Chauzy , Vincent Aranzana-Climent , Mathilde Lacroix , Luc Deroche , et al.
Antimicrobial Agents and Chemotherapy, 2022, 66 (1), ⟨10.1128/AAC.01789-21⟩
Article dans une revue hal-03615758v1

Inhibition of the Injectisome and Flagellar Type III Secretion Systems by INP1855 Impairs Pseudomonas aeruginosa Pathogenicity and Inflammasome Activation

 Ahalieyah Anantharajah , Emmanuel Faure , Julien Buyck , Charlotta Sundin , Tuulikki Lindmark , et al.
Journal of Infectious Diseases, 2016, 214 (7), pp.1105-1116. ⟨10.1093/infdis/jiw295⟩
Article dans une revue hal-02490442v1
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Semi-mechanistic pharmacodynamics modeling of aztreonam- avibactam combination to understand its antimicrobial activity against multidrug-resistant Gram(-) bacteria

 Alexia Chauzy , Bruna Gaelzer Silva Torres , Julien Buyck , Boudewijn Jonge , Christophe Adier , et al.
PAGE meeting, Jun 2019, Stockholm, Sweden
Poster de conférence hal-02528382v1

Preclinical Pharmacokinetic and Pharmacodynamic Data To Support Cefoxitin Nebulization for the Treatment of Mycobacterium abscessus

 Shachi Mehta , Vincent Aranzana-Climent , Blandine Rammaert , Nicolas Grégoire , Sandrine Marchand , et al.
Antimicrobial Agents and Chemotherapy, 2019, 63 (7), ⟨10.1128/AAC.02651-18⟩
Article dans une revue hal-02477844v1
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Semimechanistic Pharmacodynamic Modeling of Aztreonam‐Avibactam Combination to Understand Its Antimicrobial Activity Against Multidrug‐Resistant Gram‐Negative Bacteria

 Alexia Chauzy , Bruna Gaelzer Silva Torres , Julien Buyck , Boudewijn Jonge , Christophe Adier , et al.
CPT: Pharmacometrics and Systems Pharmacology, 2019, ⟨10.1002/psp4.12452⟩
Article dans une revue hal-02320523v1

Deficient Pseudomonas aeruginosa in MlaA/VacJ outer membrane lipoprotein shows decrease in rhamnolipids secretion, motility, and biofilm formation, and increase in fluoroquinolones susceptibility and innate immune response

 M. Kaur , J.M. Buyck , F. Goormaghtigh , J.-L. Decout , N. Mozaheb , et al.
Research in Microbiology, 2023, 174 (8), pp.104132. ⟨10.1016/j.resmic.2023.104132⟩
Article dans une revue hal-04473929v1

P. aeruginosa LPS stimulates calcium signaling and chloride secretion via CFTR in human bronchial epithelial cells

 Julien Buyck , J.M. Buyck , V. Verriere , R. Benmahdi , G. Higgins , et al.
Journal of Cystic Fibrosis, 2013, 12 (1), pp.60-67. ⟨10.1016/j.jcf.2012.06.007⟩
Article dans une revue hal-02490481v1

PKPD Modeling of the Inoculum Effect of Acinetobacter baumannii on Polymyxin B in vivo

 Alexia Chauzy , Grace Akrong , Vincent Aranzana-Climent , Jérémy Moreau , Laure Prouvensier , et al.
Frontiers in Pharmacology, 2022, 13, ⟨10.3389/fphar.2022.842921⟩
Article dans une revue hal-03615739v1
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Caspase-1-driven neutrophil pyroptosis and its role in host susceptibility to Pseudomonas aeruginosa

 Karin Santoni , David Pericat , Leana Gorse , Julien Buyck , Miriam Pinilla , et al.
PLoS Pathogens, 2022, 18 (7), pp.e1010305. ⟨10.1371/journal.ppat.1010305⟩
Article dans une revue hal-03738417v1

Pharmacodynamic Evaluation of the Intracellular Activity of Antibiotics towards Pseudomonas aeruginosa PAO1 in a Model of THP-1 Human Monocytes

 Julien Buyck , Paul Tulkens , Françoise van Bambeke
Antimicrobial Agents and Chemotherapy, 2013, 57 (5), pp.2310-2318. ⟨10.1128/AAC.02609-12⟩
Article dans une revue hal-02490468v1
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Pharmacodynamic modelling of β-lactam/β-lactamase inhibitor checkerboard data: illustration with aztreonam–avibactam

 Alexia Chauzy , Julien Buyck , B.L.M. de Jonge , Sandrine Marchand , N. Grégoire , et al.
Clinical Microbiology and Infection, 2019, 25 (4), pp.515.e1-515.e4. ⟨10.1016/j.cmi.2018.11.025⟩
Article dans une revue hal-02321069v1
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Semi-mechanistic PK-PD modelling of combined polymyxin B and minocycline against a polymyxin-resistant strain of Acinetobacter baumannii

 Vincent Aranzana-Climent , Julien Buyck , Younes Smani , Jerónimo Pachón-Diaz , Sandrine Marchand , et al.
Clinical Microbiology and Infection, 2020, ⟨10.1016/j.cmi.2020.01.017⟩
Article dans une revue hal-02482129v1

An improved PKPD modeling approach to characterize the pharmacodynamic interaction over time between ceftazidime/avibactam and colistin from in vitro time-kill experiments against multidrug-resistant Klebsiella pneumoniae isolates

 Romain Aubry , Julien Buyck , Laure Prouvensier , Jean-Winoc Decousser , Patrice Nordmann , et al.
Antimicrobial Agents and Chemotherapy, 2023, 67 (10), pp.e0030123. ⟨10.1128/aac.00301-23⟩
Article dans une revue hal-04227324v1

New Amphiphilic Neamine Derivatives Active against Resistant Pseudomonas aeruginosa and Their Interactions with Lipopolysaccharides

 Guillaume Sautrey , Louis Zimmermann , Magali Deleu , Alicia Delbar , Luiza Souza Machado , et al.
Antimicrobial Agents and Chemotherapy, 2014, 58 (8), pp.4420 - 4430. ⟨10.1128/AAC.02536-13⟩
Article dans une revue hal-01696330v1

Correlation between cytotoxicity induced by Pseudomonas aeruginosa clinical isolates from acute infections and IL-1β secretion in a model of human THP-1 monocytes

 Ahalieyah Anantharajah , Julien Buyck , Emmanuel Faure , Youri Glupczynski , Hector Rodriguez-Villalobos , et al.
Pathogens and Disease, 2015, 73 (7), pp.ftv049. ⟨10.1093/femspd/ftv049⟩
Article dans une revue hal-02490454v1

RX-P873, a Novel Protein Synthesis Inhibitor, Accumulates in Human THP-1 Monocytes and Is Active against Intracellular Infections by Gram-Positive (Staphylococcus aureus) and Gram-Negative (Pseudomonas aeruginosa) Bacteria

 Julien Buyck , Frédéric Peyrusson , Paul Tulkens , Françoise van Bambeke
Antimicrobial Agents and Chemotherapy, 2015, 59 (8), pp.4750-4758. ⟨10.1128/AAC.00428-15⟩
Article dans une revue hal-02490457v1

Quantitative contribution of efflux to multi-drug resistance of clinical Escherichia coli and Pseudomonas aeruginosa strains

 Olivier Cunrath , Dominik Meinel , Pauline Maturana , Joseph Fanous , Julien Buyck , et al.
EBioMedicine, 2019, 41, pp.479-487. ⟨10.1016/j.ebiom.2019.02.061⟩
Article dans une revue hal-02490365v1

Characterization of Pseudomonas aeruginosa resistance to ceftolozane-tazobactam due to ampC and/or ampD mutations observed during treatment using semi-mechanistic PKPD modeling

 Luc Deroche , Vincent Aranzana-Climent , Albane Rozenholc , Laure Prouvensier , Léa Darnaud , et al.
Antimicrobial Agents and Chemotherapy, 2023, ⟨10.1128/aac.00480-23⟩
Article dans une revue hal-04227340v1
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Semi-mechanistic pharmacokinetic/pharmacodynamics modeling of aztreonam-avibactam combination against multidrug resistant Gram(-) organisms

 Alexia Chauzy , Bruna Gaelzer Silva Torres , Julien Buyck , Emma Marquizeau , Patrice Gobin , et al.
the 28th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), Apr 2018, Madrid, Spain
Poster de conférence hal-02528294v1
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Clinical Pharmacokinetics of Daptomycin

 Nicolas Gregoire , Alexia Chauzy , Julien Buyck , Blandine Rammaert , William Couet , et al.
Clinical Pharmacokinetics, 2020, ⟨10.1007/s40262-020-00968-x⟩
Article dans une revue hal-03071620v1

Increased Susceptibility of Pseudomonas aeruginosa to Macrolides and Ketolides in Eukaryotic Cell Culture Media and Biological Fluids Due to Decreased Expression of oprM and Increased Outer-Membrane Permeability

 Julien Buyck , Patrick Plesiat , H. Traore , F. Vanderbist , Paul Tulkens , et al.
Clinical Infectious Diseases, 2012, 55 (4), pp.534 - 542. ⟨10.1093/cid/cis473⟩
Article dans une revue hal-01695413v1

Role of MexAB-OprM in intrinsic resistance of Pseudomonas aeruginosa to temocillin and impact on the susceptibility of strains isolated from patients suffering from cystic fibrosis

 Julien Buyck , Sophie Guénard , Patrick Plesiat , Paul Tulkens , Françoise van Bambeke
Journal of Antimicrobial Chemotherapy, 2012, 67 (3), pp.771 - 775. ⟨10.1093/jac/dkr543⟩
Article dans une revue hal-01695421v1

Salicylidene Acylhydrazides and Hydroxyquinolines Act as Inhibitors of Type Three Secretion Systems in Pseudomonas aeruginosa by Distinct Mechanisms

 Ahalieyah Anantharajah , Julien Buyck , Charlotta Sundin , Paul Tulkens , Marie-Paule Mingeot-Leclercq , et al.
Antimicrobial Agents and Chemotherapy, 2017, 61 (6), pp.515.e1-515.e4. ⟨10.1128/AAC.02566-16⟩
Article dans une revue hal-02490371v1

Pharmacodynamics of ceftazidime/avibactam against extracellular and intracellular forms of Pseudomonas aeruginosa

 Julien Buyck , C. Luyckx , G. Muccioli , K. Krause , W. Nichols , et al.
Journal of Antimicrobial Chemotherapy, 2017, pp.dkw587. ⟨10.1093/jac/dkw587⟩
Article dans une revue hal-02490439v1

Activities of Antibiotic Combinations against Resistant Strains of Pseudomonas aeruginosa in a Model of Infected THP-1 Monocytes

 Julien Buyck , Paul Tulkens , Françoise van Bambeke
Antimicrobial Agents and Chemotherapy, 2014, 59 (1), pp.258-268. ⟨10.1128/AAC.04011-14⟩
Article dans une revue hal-02490461v1

Outer membrane permeability: Antimicrobials and diverse nutrients bypass porins in Pseudomonas aeruginosa

 Johanna Ude , Vishwachi Tripathi , Julien Buyck , Sandra Söderholm , Olivier Cunrath , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (31), ⟨10.1073/pnas.2107644118⟩
Article dans une revue hal-03615786v1

EEF2-inactivating toxins engage the NLRP1 inflammasome and promote epithelial barrier disruption

 Miriam Pinilla , Raoul Mazars , Romain Vergé , Leana Gorse , Margaux Paradis , et al.
Journal of Experimental Medicine, 2023, 220 (10), ⟨10.1084/jem.20230104⟩
Article dans une revue hal-04227358v1
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