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Lymphatic Vasculature Requires Estrogen Receptor- Signaling to Protect From Lymphedema

Florent Morfoisse , Florence Tatin , Benoit Chaput , Nicole Therville , Charlotte Vaysse , et al.
Arteriosclerosis, Thrombosis, and Vascular Biology, 2018, 38 (6), pp.1346-1357. ⟨10.1161/ATVBAHA.118.310997⟩
Article dans une revue hal-01863214v1

Targeting the sphingolipid metabolism to defeat pancreatic cancer cell resistance to the chemotherapeutic gemcitabine drug.

Julie Guillermet-Guibert , Lise Davenne , Dimitri Pchejetski , Nathalie Saint-Laurent , Leyre Brizuela , et al.
Molecular Cancer Therapeutics, 2009, 8 (4), pp.809-20. ⟨10.1158/1535-7163.MCT-08-1096⟩
Article dans une revue inserm-00409953v1
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PI3K functions as a hub in mechanotransduction

M. Di-Luoffo , Zacchari Ben-Meriem , P. Lefebvre , Morgan Delarue , Julie Guillermet-Guibert
Trends in Biochemical Sciences, 2021, 46 (11), pp.878-888. ⟨10.1016/j.tibs.2021.05.005⟩
Article dans une revue hal-03252135v1
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Paclitaxel induces lymphatic endothelial cells autophagy to promote metastasis

Audrey Zamora , Melinda Alves , Charlotte Chollet , Nicole Therville , Tiffany Fougeray , et al.
Cell Death and Disease, 2019, 10 (12), 12 p. ⟨10.1038/s41419-019-2181-1⟩
Article dans une revue hal-02622895v1
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Reprogramming of endothelial gene expression by tamoxifen inhibits angiogenesis and ERα-negative tumor growth

Chanaëlle Febrissy , Marine Adlanmerini , Christel Péqueux , Frederic Boudou , Melissa Buscato , et al.
Theranostics, 2024, Theranostics, 14 (1), pp.249-264. ⟨10.7150/thno.87306⟩
Article dans une revue hal-04384793v1
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Experimental pancreatic cancer develops in soft pancreas: novel leads for an individualized diagnosis by ultrafast elasticity imaging

Nicole Therville , Silvia Arcucci , Aurélie Vertut , Fernanda Ramos-Delgado , Dina Ferreira da Mota , et al.
Theranostics, 2019, 9, ⟨10.7150/thno.34066⟩
Article dans une revue hal-02500120v1
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Signal-Targeted Therapies and Resistance Mechanisms in Pancreatic Cancer: Future Developments Reside in Proteomics

Celia Cintas , Thibaut Douche , Nicole Therville , Silvia Arcucci , Fernanda Ramos-Delgado , et al.
Cancers, 2018, 10 (6), pp.174. ⟨10.3390/cancers10060174⟩
Article dans une revue hal-02500132v1

Upregulated Apelin Signaling in Pancreatic Cancer Activates Oncogenic Signaling Pathways to Promote Tumor Development

Carline Chaves-Almagro , Johanna Auriau , Alizée Dortignac , Pascal Clerc , Hubert Lulka , et al.
International Journal of Molecular Sciences, 2022, 23 (18), pp.10600. ⟨10.3390/ijms231810600⟩
Article dans une revue hal-03782763v1

Laser-assisted 3D bioprinting of exocrine pancreas spheroid models for cancer initiation study

Davit Hakobyan , Chantal Medina , Nathalie Dusserre , Marie-Laure Stachowicz , Charles Handschin , et al.
Biofabrication, 2020, 12 (3), pp.035001. ⟨10.1088/1758-5090/ab7cb8⟩
Article dans une revue inserm-02870465v1

Upregulated Apelin Signaling in Pancreatic Cancer Activates Oncogenic Signaling Pathways to Promote Tumor Development

Carline Chaves-Almagro , Johanna Auriau , Alizée Dortignac , Pascal Clerc , Hubert Lulka , et al.
International Journal of Molecular Sciences, 2022, 23 (18), pp.10600. ⟨10.3390/ijms231810600⟩
Article dans une revue hal-04273227v1

Nucleolin Promotes Heat Shock-Associated Translation of VEGF-D to Promote Tumor Lymphangiogenesis

F. Morfoisse , F. Tatin , F. Hantelys , A. Adoue , A.-C. Helfer , et al.
Cancer Research, 2016, 76 (15), pp.4394-4405. ⟨10.1158/0008-5472.CAN-15-3140⟩
Article dans une revue hal-02294493v1
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Mechanical Control of Cell Proliferation Increases Resistance to Chemotherapeutic Agents

Ilaria Francesca Rizzuti , Pietro Mascheroni , Silvia Arcucci , Zacchari Ben-Mériem , Audrey Prunet , et al.
Physical Review Letters, 2020, 125 (12), pp.128103. ⟨10.1103/PhysRevLett.125.128103⟩
Article dans une revue hal-02943906v1
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Pancreatic cancer intrinsic PI3Kα activity accelerates metastasis and rewires macrophage component

Benoit Thibault , Fernanda Ramos‐delgado , Elvire Pons‐tostivint , Nicole Therville , Celia Cintas , et al.
EMBO Molecular Medicine, 2021, 13 (7), pp.e13502. ⟨10.15252/emmm.202013502⟩
Article dans une revue hal-03625379v1

Acinar-to-Ductal Metaplasia Induced by Transforming Growth Factor Beta Facilitates KRAS G12D -driven Pancreatic Tumorigenesis

Nicolas Chuvin , David Vincent , Roxane Pommier , Lindsay B Alcaraz , Johann Gout , et al.
Cellular and Molecular Gastroenterology and Hepatology, 2017, 4 (2), pp.263-282. ⟨10.1016/j.jcmgh.2017.05.005⟩
Article dans une revue hal-02284709v1
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p110α-dependent hepatocyte signaling is critical for liver gene expression and its rewiring in MASLD

Marion Régnier , Arnaud Polizzi , Tiffany Fougeray , Anne Fougerat , Prunelle Perrier , et al.
Article dans une revue hal-04442467v1
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Novel Role for p110β PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli Cells

Julie Guillermet-Guibert , Lee B. Smith , Guillaume Halet , Maria A. Whitehead , Wayne Pearce , et al.
PLoS Genetics, 2015, 11 (7), pp.e1005304. ⟨10.1371/journal.pgen.1005304⟩
Article dans une revue hal-01175530v1
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Hypoxia induces VEGF-C expression in metastatic tumor cells via a HIF-1α-independent translation-mediated mechanism

Florent Morfoisse , Anna Kuchnio , Clément Frainay , Anne Gomez-Brouchet , Marie-Bernadette Delisle , et al.
Cell Reports, 2014, 6 (1), pp.155-167. ⟨10.1016/j.celrep.2013.12.011⟩
Article dans une revue hal-02631811v1

The biomechanical context influences the PI3K output signaling in breast and pancreatic cancer cells

M. Di-Luoffo , C. Schmitter , E.C. Barrere , N. Therville , Morgan Delarue , et al.
2022
Pré-publication, Document de travail hal-03808261v1

Phosphoproteomics identifies PI3K inhibitor-selective adaptive responses in pancreatic cancer cell therapy and resistance

C Cintas , T Douche , Z Dantes , E Mouton-Barbosa , Mp Bousquet , et al.
2021
Pré-publication, Document de travail hal-03223423v1
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Pancreatic preneoplastic lesions plasma signatures and biomarkers based on proteome profiling of mouse models

Laetitia Ligat , Nathalie Saint-Laurent , Aïcha El-Mrani , Véronique Gigoux , Talal Al Saati , et al.
British Journal of Cancer, 2015, 113 (11), pp.1590 - 1598. ⟨10.1038/bjc.2015.370⟩
Article dans une revue hal-01926958v1