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G-Quadruplex Identification in the Genome of Protozoan Parasites Points to Naphthalene Diimide Ligands as New Antiparasitic Agents

Efres Belmonte-Reche , Marta Martínez-García , Aurore Guédin , Michela Zuffo , Matilde Arévalo-Ruiz , et al.
Journal of Medicinal Chemistry, 2018, 61 (3), pp.1231-1240. ⟨10.1021/acs.jmedchem.7b01672⟩
Article dans une revue hal-02863564v1

Genome editing in the human malaria parasite Plasmodium falciparum using the CRISPR-Cas9 system

Mehdi Ghorbal , Molly Gorman , Cameron Ross Macpherson , Rafael Miyazawa Martins , Artur Scherf , et al.
Nature Biotechnology, 2014, 32 (8), pp.819-821. ⟨10.1038/nbt.2925⟩
Article dans une revue hal-03129899v1
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Identification of long regulatory elements in the genome of Plasmodium falciparum and other eukaryotes

Christophe Menichelli , Vincent Guitard , Rafael Miyazawa Martins , Sophie Lèbre , José Juan Lopez-Rubio , et al.
PLoS Computational Biology, 2021, 17 (4), pp.e1008909. ⟨10.1371/journal.pcbi.1008909⟩
Article dans une revue hal-03253460v1

A Critical Role of Perinuclear Filamentous Actin in Spatial Repositioning and Mutually Exclusive Expression of Virulence Genes in Malaria Parasites

Qingfeng Zhang , Yufu Huang , Yilong Zhang , Xiaonan Fang , Aurelie Claes , et al.
Cell Host & Microbe, 2011, 10 (5), pp.451-463. ⟨10.1016/j.chom.2011.09.013⟩
Article dans une revue hal-03157399v1
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Plasmodium falciparum gametocyte-infected erythrocytes do not adhere to human primary erythroblasts

Gaëlle Neveu , Florian Dupuy , Meriem Ladli , Daniela Barbieri , Bernina Naissant , et al.
Scientific Reports, 2018, 8 (1), ⟨10.1038/s41598-018-36148-y⟩
Article dans une revue hal-02390751v1

Regulation of PfEMP1–VAR2CSA translation by a Plasmodium translation-enhancing factor

Sherwin Chan , Alejandra Frasch , Chandra Sekhar Chan , Jun-Hong Ch'Ng , Maria del Pilar Quintana , et al.
Nature Microbiology, 2017, 2, pp.17068. ⟨10.1038/nmicrobiol.2017.68⟩
Article dans une revue hal-02005504v1
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Plasmodium falciparum sexual parasites develop in human erythroblasts and affect erythropoiesis

Gaëlle Neveu , Cyrielle Richard , Prativa Kumari Behera , Fiona Volpe , Florian Dupuy , et al.
Blood, 2020, Online ahead of print (12), pp.1381-1393. ⟨10.1182/blood.2019004746⟩
Article dans une revue pasteur-02890973v1
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Phosphorylation of the VAR2CSA extracellular region is associated with enhanced adhesive properties to the placental receptor CSA

Dominique Dorin-Semblat , Marilou Tétard , Aurélie Claës , Jean-Philippe Semblat , Sébastien Dechavanne , et al.
PLoS Biology, 2019, 17 (6), pp.e3000308. ⟨10.1371/journal.pbio.3000308⟩
Article dans une revue inserm-02279477v1
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A single amino acid substitution (H451Y) in Leishmania calcium-dependent kinase SCAMK confers high tolerance and resistance to antimony

Baptiste Vergnes , Elodie Gazanion , Cédric Mariac , Miléna Du Manoir , Lauriane Sollelis , et al.
Journal of Antimicrobial Chemotherapy, 2019, 74 (11), pp.3231-3239. ⟨10.1093/jac/dkz334⟩
Article dans une revue hal-02494096v1
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Strand-specific RNA-Seq reveals widespread and developmentally regulated transcription of natural antisense transcripts in Plasmodium falciparum.

Nicolai T. Siegel , Chung-Chau Hon , Qinfeng Zhang , Jose-Juan Lopez-Rubio , Christine Scheidig-Benatar , et al.
BMC Genomics, 2014, 15 (1), pp.150. ⟨10.1186/1471-2164-15-150⟩
Article dans une revue inserm-00981322v1
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PfGBP2 is a novel G‐quadruplex binding protein in Plasmodium falciparum

Pratima Gurung , Ana Rita Gomes , Rafael Martins , Stefan Juranek , Patrizia Alberti , et al.
Cellular Microbiology, 2021, 23 (4), pp.e13303. ⟨10.1111/cmi.13303⟩
Article dans une revue hal-03152279v1
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Discovery of a novel and conserved Plasmodium falciparum exported protein that is important for adhesion of PfEMP1 at the surface of infected erythrocytes

Adéla Nacer , Aurélie Claës , Amy Roberts , Christine Scheidig-Benatar , Hiroshi Sakamoto , et al.
Cellular Microbiology, 2015, 17 (8), pp.1205-16. ⟨10.1111/cmi.12430⟩
Article dans une revue pasteur-02557990v1
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ELA/APELA precursor cleaved by furin displays tumor suppressor function in renal cell carcinoma through mTORC1 activation

Fabienne Soulet , Clément Bodineau , Katarzyna Hooks B. , Jean Descarpentrie , Isabel D. Alves , et al.
JCI Insight, 2020, 5 (14), ⟨10.1172/jci.insight.129070⟩
Article dans une revue hal-03084443v1
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PfAlbas constitute a new eukaryotic DNA/RNA-binding protein family in malaria parasites.

Arnaud Chêne , Shruthi S Vembar , Loïc Rivière , José Juan Lopez-Rubio , Aurelie Claes , et al.
Nucleic Acids Research, 2012, 40(7), pp.3066-77. ⟨10.1093/nar/gkr1215⟩
Article dans une revue hal-01101391v1
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Identification of long regulatory elements in the genome of Plasmodium falciparum and other eukaryotes

Christophe Menichelli , Vincent Guitard , Rafael Martins , Sophie Lèbre , José‑juan Lopez‑rubio , et al.
2020
Pré-publication, Document de travail hal-03024898v1
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Involvement of Plasmodium falciparum protein kinase CK2 in the chromatin assembly pathway.

Eeshita Dastidar , Guillem Dayer , Zoe Holland , Dominique Dorin-Semblat , Aurélie Claes , et al.
BMC Biology, 2012, 10 (1), pp.5. ⟨10.1186/1741-7007-10-5⟩
Article dans une revue inserm-00677275v1
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Plasmodium falciparum sexual parasites regulate infected erythrocyte permeability

Guillaume Bouyer , Daniela Barbieri , Florian Dupuy , Anthony Marteau , Abdoulaye Sissoko , et al.
Communications Biology, 2020, 3 (1), ⟨10.1038/s42003-020-01454-7⟩
Article dans une revue hal-03036079v1
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First efficient CRISPR-Cas9-mediated genome editing in Leishmania parasites.

Lauriane Sollelis , Mehdi Ghorbal , Cameron Ross Macpherson , Rafael Miyazawa Martins , Nada Kuk , et al.
Cellular Microbiology, 2015, 17 (10), pp.1405-1412. ⟨10.1111/cmi.12456⟩
Article dans une revue hal-01992713v1

A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria

Alassane Mbengue , Souvik Bhattacharjee , Trupti Pandharkar , Haining Liu , Guillermina Estiu , et al.
Nature, 2015, 520 (7549), pp.683-687. ⟨10.1038/nature14412⟩
Article dans une revue hal-02427334v1
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Genome wide distribution of G-quadruplexes and their impact on gene expression in malaria parasites

Elodie Gazanion , Laurent Lacroix , Patrizia Alberti , Pratima Gurung , Sharon Wein , et al.
PLoS Genetics, 2020, 16 (7), pp.e1008917. ⟨10.1371/journal.pgen.1008917⟩
Article dans une revue inserm-02950955v1
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Characterization of an A-kinase anchoring protein-like suggests an alternative way of PKA anchoring in Plasmodium falciparum

Kossiwa Bandje , Bernina Naissant , Pascal Bigey , Murielle Lohezic , Marlène Vayssières , et al.
Malaria Journal, 2016, 15 (1), pp.248. ⟨10.1186/s12936-016-1275-9⟩
Article dans une revue inserm-01310216v1