jerome toutain

Documents

Présentation

Publications

myriam-bernaudin

	Hypoxia-induced activation of NDR2 underlies brain metastases from Non-Small Cell Lung Cancer Jérôme Levallet , Tiphaine Biojout , Céline Bazille , Manon Douyère , Fatéméh Dubois Cell Death and Disease, 2023, 14, pp.823. ⟨10.1038/s41419-023-06345-3⟩ Article dans une revue hal-04404933v1
	Physical Activity Attenuates Brain Irradiation-Associated Skeletal Muscle Damage in the Rat Julie Bécam , Gwenn Ropars , Fatima-Azzahra Dwiri , Carole Brunaud , Jérôme Toutain International Journal of Radiation Oncology, Biology, Physics, 2023, 118 (4), pp.1081-1093. ⟨10.1016/j.ijrobp.2023.10.007⟩ Article dans une revue hal-04294870v1
	Assessment of hypoxia and oxidative-related changes in a lung-derived brain metastasis model by [64Cu][Cu(ATSM)] PET and proteomic studies Jade Fantin , Jérôme Toutain , Elodie A. Pérès , Benoit Bernay , Sarina Maya Mehani EJNMMI Research, 2023, 13 (102), ⟨10.1186/s13550-023-01052-8⟩ Article dans une revue hal-04308804v1
	Magnetic resonance imaging of hypoxia in acute stroke: a cross‐validation study against FMISO‐positron emission tomography Valable Samuel , Jérôme Toutain , Didier Divoux , Laurent Chazalviel , Aurélien Corroyer-Dulmont NMR in Biomedicine, 2022, 36 (3), pp.e4858. ⟨10.1002/nbm.4858⟩ Article dans une revue hal-03831642v1
	Multimodal evaluation of hypoxia in brain metastases of lung cancer and interest of hypoxia image-guided radiotherapy Aurélien Corroyer-Dulmont , Valable Samuel , Jade Fantin , Laurent Chatre , Jérôme Toutain Scientific Reports, 2021, 11 (1), pp.11239. ⟨10.1038/s41598-021-90662-0⟩ Article dans une revue hal-03244249v1
	Impact of Hypoxia on Carbon Ion Therapy in Glioblastoma Cells: Modulation by LET and Hypoxia-Dependent Genes Samuel Valable , Aurélie Gérault , Gaelle Lambert , Marine Leblond , Clement Anfray Cancers, 2020, 12 (8), pp.2019. ⟨10.3390/cancers12082019⟩ Article dans une revue hal-02912590v1
	Nanosized zeolites as a gas delivery platform in a glioblastoma model Clement Anfray , Sarah Komaty , Aurélien Corroyer-Dulmont , Moussa Zaarour , Charly Hélaine Biomaterials, 2020, 257, pp.120249. ⟨10.1016/j.biomaterials.2020.120249⟩ Article dans une revue hal-02912573v1
	64Cu-ATSM/64Cu-Cl2 and their relationship to hypoxia in glioblastoma: a preclinical study Elodie A. Pérès , Toutain Jérôme , Louis-Paul Paty , Didier Divoux , Méziane Ibazizène EJNMMI Research, 2019, 9 (114), ⟨10.1186/s13550-019-0586-6⟩ Article dans une revue hal-02409461v1
	VCAM-1 Targeted Alpha-Particle Therapy for Early Brain Metastases Aurélien Corroyer-Dulmont , Samuel Valable , Nadia Falzone , Anne-Marie Frelin-Labalme , Ole Tietz Neuro-Oncology, 2019, 22 (3), pp.357-368. ⟨10.1093/neuonc/noz169⟩ Article dans une revue hal-02346582v1
	Assessment of behavioural deficits following ischaemic stroke in the marmoset Rozenn Le Gal , Myriam Bernaudin , Jérôme Toutain , Omar Touzani Behavioural Brain Research, 2018, 352, pp.151-160. ⟨10.1016/j.bbr.2017.07.042⟩ Article dans une revue hal-01994459v1
	A heparan sulfate-based matrix therapy reduces brain damage and enhances functional recovery following stroke Yacine Khelif , Jérôme Toutain , Marie-Sophie Quittet , Sandrine Chantepie , Xavier Laffray Theranostics, 2018, 8 (21), pp.5814-5827. ⟨10.7150/thno.28252⟩ Article dans une revue hal-02018014v1
	Imaging of brain oxygenation with magnetic resonance imaging : A validation with positron emission tomography in the healthy and tumoural brain. S Valable , A Corroyer-Dulmont , A Chakhoyan , L Durand , J Toutain Journal of Cerebral Blood Flow and Metabolism, 2017, 37 (7), pp.2584-2597. ⟨10.1177/0271678X16671965⟩ Article dans une revue hal-01575065v1
	Pharmacological inhibition of myostatin improves skeletal muscle mass and function in a mouse model of stroke Marine Maud Desgeorges , Xavier Devillard , Jérôme Toutain , Josiane Castells , Didier Divoux Scientific Reports, 2017, 7 (1), pp.14000. ⟨10.1038/s41598-017-13912-0⟩ Article dans une revue hal-02043512v1
	Carbogen-induced increases in tumor oxygenation depend on the vascular status of the tumor: A multiparametric MRI study in two rat glioblastoma models. A Chakhoyan , A Corroyer-Dulmont , M.M. Leblond , A Gérault , J Toutain Journal of Cerebral Blood Flow and Metabolism, 2017, 37 (6), pp.2270-2282. ⟨10.1177/0271678X16663947⟩ Article dans une revue hal-01575557v1
	Multimodal imaging based on MRI and PET reveals [(18)F]FLT PET as a specific and early indicator of treatment efficacy in a preclinical model of recurrent glioblastoma A Corroyer-Dulmont , Elodie A. Pérès , An Gérault , A Savina , F Bouquet European Journal of Nuclear Medicine and Molecular Imaging, 2016, 43 (4), pp.682-694. ⟨10.1007/s00259-015-3225-0⟩ Article dans une revue hal-01575614v1
	Chronic arterial hypertension impedes glioma growth: a multiparametric MRI study in the rat. Al Letourneur , S Roussel , M Bernaudin , F Fillesoye , J Toutain Hypertension Research, 2015, 38 ((11)), pp.723-32. ⟨10.1038/hr.2015.66⟩ Article dans une revue hal-01587404v1
	Effects of mesenchymal stem cell therapy, in association with pharmacologically active microcarriers releasing VEGF, in an ischaemic stroke model in the rat. Ms Quittet , O Touzani , L Sindji , J Cayon , F Fillesoye Acta Biomaterialia, 2015, 15, pp.77-88. ⟨10.1016/j.actbio.2014.12.017⟩ Article dans une revue hal-01577870v1
	Silencing erythropoietin receptor on glioma cells reinforces efficacy of temozolomide and X-rays through senescence and mitotic catastrophe Elodie A. Pérès , An Gérault , S Valable , S Roussel , J Toutain Oncotarget, 2015, 6 (4), pp.2101-19. ⟨10.18632/oncotarget.2937⟩ Article dans une revue hal-01576268v1
	Molecular mechanisms of skeletal muscle atrophy in a mouse model of cerebral ischemia Marine Maud Desgeorges , Xavier Devillard , Jérôme Toutain , Didier Divoux , Josiane Castells Stroke, 2015, 46 (6), pp.1673-80. ⟨10.1161/STROKEAHA.114.008574⟩ Article dans une revue hal-01585137v1
	Detection of glioblastoma response to temozolomide combined with bevacizumab based on µMRI and µPET imaging reveals [$^{18}$F]-fluoro-L-thymidine as an early and robust predictive marker for treatment efficacy Aurélien Corroyer-Dulmont , Elodie A. Pérès , Edwige Petit , Jean-Sébastien Guillamo , Nathalie Varoqueaux Neuro-Oncology, 2013, 15 (1), pp.41 - 56. ⟨10.1093/neuonc/nos260⟩ Article dans une revue hal-01655989v1
	Noninvasive assessment of hypoxia with 3-[18F]-fluoro-1-(2-nitro-1-imidazolyl)-2-propanol ([18F]-FMISO): a PET study in two experimental models of human glioma Aurélien Corroyer-Dulmont , Elodie A. Pérès , Edwige Petit , Lucile Durand , Léna Marteau Biological Chemistry, 2013, 394 (4), ⟨10.1515/hsz-2012-0318⟩ Article dans une revue hal-01660598v1
	Maternal hypertension during pregnancy modifies the response of the immature brain to hypoxia-ischemia: sequential MRI and behavioral investigations. Annelise Letourneur , Thomas Freret , Simon Roussel , Michel Boulouard , Didier Divoux Experimental Neurology, 2012, 233 (1), pp.264-72. ⟨10.1016/j.expneurol.2011.10.014⟩ Article dans une revue hal-00862822v1
	The adhesive removal test: a sensitive method to assess sensorimotor deficits in mice. Valentine Bouet , Michel Boulouard , Jérôme Toutain , Didier Divoux , Myriam Bernaudin Nature Protocols, 2009, 4 (10), pp.1560-4. ⟨10.1038/nprot.2009.125⟩ Article dans une revue hal-00863258v1
	Delayed hypoxic postconditioning protects against cerebral ischemia in the mouse. Claire Leconte , Emmanuelle Tixier , Thomas Freret , Jérôme Toutain , Romaric Saulnier Stroke, 2009, 40 (10), pp.3349-55. ⟨10.1161/STROKEAHA.109.557314⟩ Article dans une revue hal-00863295v1
	Combined therapeutic strategy using erythropoietin and mesenchymal stem cells potentiates neurogenesis after transient focal cerebral ischemia in rats. Elise Esneault , Emilie Pacary , Dauphou Eddi , Thomas Freret , Emmanuelle Tixier Journal of Cerebral Blood Flow and Metabolism, 2008, 28 (9), pp.1552-63. ⟨10.1038/jcbfm.2008.40⟩ Article dans une revue hal-00863330v1
	Expression of the gene encoding the pro-apoptotic BNIP3 protein and stimulation of hypoxia-inducible factor-1alpha (HIF-1alpha) protein following focal cerebral ischemia in rats J. Althaus , M. Bernaudin , E. Petit , J. Toutain , O. Touzani Neurochemistry International, 2006, 48, pp.687-695 Article dans une revue hal-00022247v1

	Preclinical model of radiation induced-neurotoxicity: longitudinal and multiparametric evaluation of tissue injury and cognitive deficits in the rat Elodie A. Pérès , G. Ropars , Fatima-Azzahra Dwiri , Carole Brunaud , Jérôme Toutain Assemblée générale du GDR Mi2B, Oct 2023, Bordeaux, France Communication dans un congrès hal-04233371v1
	Hadrontherapy to target glioblastoma stem cells to overcome radioresistance Juliette Aury-Landas , E.A. Pérès , Nolwenn Pasquet , C Hélaine , D Lebhertz Assemblée générale du GDR Mi2B (Outils et méthodes nucléaires pour la lutte contre le cancer), Oct 2023, Bordeaux, France Communication dans un congrès hal-04262139v1
	Etude préclinique de l'hypoxie tumorale par imagerie multimodale en IRM et TEP dans les métastases cérébrales : intérêt du [64Cu]-ATSM ? Jade Fantin , Jérôme Toutain , Aurélien Corroyer-Dulmont , Elodie A. Pérès , Mickael Bourgeois 2ème Rencontre Scientifique sur les tumeurs cérébrales "Détecter et Cibler la Récidive", Feb 2022, e-congrès, France Communication dans un congrès hal-03699245v1
	Preclinical model of radiation induced-neurotoxicity: longitudinal and multiparametric evaluation of tissue injury and cognitive deficits in the rat Gwenn Ropars , Fatima-Azzahra Dwiri , Carole Brunaud , Jérôme Toutain , Laurent Chatre 1er congrès de la Société Française de Biologie des Radiations, Nov 2022, Agay-Saint Raphaël, France Communication dans un congrès hal-04192035v1
	The physical activity attenuates the brain irradiation-induced cerebral and skeletal muscle injuries in the adult rat Julie Bécam , Gwenn Ropars , Fatima-Azzahra Dwiri , Jérôme Toutain , Laurent Chazalviel 5th Conference on Small Animal Precision Image-Guided Radiotherapy, Mar 2022, Munich, Germany Communication dans un congrès hal-03618436v1
	The whole-brain irradiation induces skeletal muscle damage in the rat Julie Bécam , Gwenn Ropars , Fatima-Azzahra Dwiri , Jérôme Toutain , Laurent Chazalviel Cancer and Cancer Treatments on Cognitive Functions: At the Era of Comprehensive Mechanisms, Jul 2022, Paris, France Communication dans un congrès hal-03760852v1
	Preclinical model of radiation induced-neurotoxicity: longitudinal and multiparametric evaluation of tissue injury and cognitive deficits in the rat Gwenn Ropars , Fatima-Azzahra Dwiri , Brunaud Carole , Jérôme Toutain , Laurent Chatre Cancer and Cancer Treatments on Cognitive Functions: At the Era of Comprehensive Mechanisms, Jul 2022, Paris, France Communication dans un congrès hal-03760839v1
	Etude préclinique de l’hypoxie tumorale par imagerie multimodale en IRM et TEP dans les métastases cérébrales : intérêt du [64Cu]-ATSM ? Jade Fantin , Jérôme Toutain , Aurélien Corroyer-Dulmont , Elodie A. Pérès , Mickael Bourgeois 14èmes journées scientifiques du Cancéropôle Nord-Ouest, May 2022, Deauville, France Communication dans un congrès hal-03699264v1
	MRI biomarkers for the detection of radiation-induced brain injury associated to cognitive deficits G. Ropars , Fatima-Azzahra Dwiri , R. Le Gal , Jérôme Toutain , Brunaud Carole 5th Conference on Small Animal Precision Image-Guided Radiotherapy, Mar 2022, Munich, Germany Communication dans un congrès hal-03643196v1
	Overcoming hypoxia-induced radioresistance of glioblastoma cells by hadrontherapy Nolwenn Pasquet , Elodie A. Pérès , Jérôme Toutain , Myriam Bernaudin , Valable Samuel ERRS 2021 - 46th Annual Meeting of the European Radiation Research Society, UNicaen; ERRS Society, Nov 2021, Caen, France Communication dans un congrès hal-03616264v1
	L’activité physique réduit la cachexie observée après irradiation cérébrale chez le rat Julie Bécam , Gwenn Ropars , Fatima-Azzahra Dwiri , Jérôme Toutain , Laurent Chazalviel 13èmes journées scientifiques du Cancéropôle Nord-Ouest, Oct 2021, Deauville, France Communication dans un congrès hal-03467478v1
	Development and in vivo preclinical validation of [18F]FLUSONIM, a highly hydrophilic 18F-labelled 2-nitroimidazole derivative for high performance hypoxia PET imaging C. Maingueneau , A.-E. Lafargue , F. Fillesoye , J. Toutain , S. Valable 4th Nuclear Technologies for Health Symposium, NTHS2020, Feb 2020, Nantes, France Communication dans un congrès hal-02489356v1
	Early brain metastases treatment using VCAM-1 targeted alpha-particle therapy A Corroyer-Dulmont , S Valable , N Falzone , Am Frelin-Labalme , O Tietz 4th Nuclear Technologies for Health Symposium, NTHS2020, Feb 2020, Nantes, France Communication dans un congrès hal-02488870v1
	Relevance of multiparametric MRI to accurately detect radiation-induced brain injury in the rat C. Brunaud , S. Valable , F.A. Dwiri , G. Ropars , J. Toutain Journée de travail Cancéropôle Nord-Ouest, Axe 3 « Imagerie et adaptation thérapeutique » : Place de l'imagerie médicale dans la précision thérapeutique, Dec 2020, e-congrès, France Communication dans un congrès hal-03167478v1
	Evaluation préclinique de l’influence d'anesthésiques intraveineux sur les cellules de glioblastome et l’efficacité des traitements par chimio- et radiothérapie K. Monthé-Sagan , O. Touzani , J. Toutain , J.L. Hanouz , Myriam Bernaudin Société Française d'Anesthésie-Réanimation (SFAR), Sep 2020, Paris, France Communication dans un congrès hal-02960958v1
	VCAM-1 targeted alpha-particle therapy for early brain metastases A Corroyer-Dulmont , S Valable , N Falzone , A.M. Frelin-Labalme , O Tietz 4ème Journée Normande de Recherche Biomédicale, JNRB 2019, Nov 2019, Caen, France Communication dans un congrès hal-02402378v1
	Hypoxia image-Guided Radiotherapy for the treatment of brain metastases from primary lung cancer, a preclinical study. Aurélien Corroyer-Dulmont , Samuel Valable , Jérôme Toutain , Didier Divoux , Méziane Ibazizene 3ème Congrès National d'Imagerie du Vivant (CNIV), Feb 2019, Paris, France Communication dans un congrès hal-02200579v1
	Evaluation par IRM des dommages cérébraux induits par la radiothérapie dans un modèle de rat Elodie Pérès , Jérôme Toutain , Carole Brunaud , Omar Touzani , Edwige Petit 3ème Congrès National d'Imagerie du Vivant (CNIV), Feb 2019, Paris, France Communication dans un congrès hal-02266830v1
	VCAM-1 targeted alpha-particle therapy for early brain metastases Aurélien Corroyer-Dulmont , Samuel Valable , Nadia Falzone , Anne-Marie Frelin-Labalme , Ole Tietz ICRR 2019, Aug 2019, Manchester, United Kingdom Communication dans un congrès hal-02266822v1
	Etude multiparamétrique des effets de l'irradiation cérébrale chez le rat : des altérations tissulaires jusqu'aux déficits cognitifs Gwenn Ropars , Rozenn Le Gal , Fatima-Azzahra Dwiri , Jérôme Toutain , Carole Brunaud 12èmes journées scientifiques du Cancéropôle Nord-Ouest, May 2019, Deauville, France Communication dans un congrès hal-02266824v1
	A combination of stem cells and an extracellular matrix agent as a new therapeutic strategy for ischemic stroke Y Khelif , R Le Gal , C Renoult , J Toutain , Ms Quittet 7th Mediterranean Neuroscience Conference MNS2019, Jun 2019, Marrakech, Morocco Communication dans un congrès hal-02406380v1
	Evaluation des dommages cérébraux radio-induits par l’exposition à de faibles et fortes doses de rayonnements ionisants sur un modèle de rat adulte Elodie Pérès , Jérôme Toutain , Carole Brunaud , François Kauffmann , Mikaël Naveau 12èmes journées scientifiques du Cancéropôle Nord-Ouest, May 2019, Deauville, France Communication dans un congrès hal-02266823v1
	Développement et validation préclinique in vivo du [18F]FLUSONIM pour l’imagerie TEP de l’hypoxie de haute performance Clémence Maingueneau , Anne-Élodie Lafargue , Fabien Fillesoye , Jérôme Toutain , Samuel Valable Journées scientifiques du Cancéropôle Nord-Ouest, Dec 2019, Lille, France Communication dans un congrès hal-02414509v1
	Hypoxia imaging: interest of Image-Guided Radiotherapy for the treatment of brain metastases from lung cancer, a preclinical study A Corroyer-Dulmont , S Valable , J Toutain , D Divoux , M Ibazizène Workshop “Imaging and therapeutic targeting in cancerology: New advances and trends in preclinical and clinical studies”., Sep 2018, Le Bono, France Communication dans un congrès hal-02267161v1
	Hypoxia imaging: interest of Image-Guided Radiotherapy for the treatment of brain metastases from lung cancer, a preclinical study A Corroyer-Dulmont , S Valable , J Toutain , D Divoux , M Ibazizène 3ème Journée Normande de Recherche Biomédicale, JNRB 2018, Sep 2018, Rouen, France Communication dans un congrès hal-02267175v1
	Heparan sulfate mimetics are neuroprotective and neuroregenerative agents for ischemic stroke. Y Khelif , J Toutain , Ms Quittet , S Chantepie , X Laffray Bioregate Forum - European Regenrative Medicine, Dec 2018, Nantes, France Communication dans un congrès hal-02267171v1
	An analogue of heparan sulfate as a novel neuroprotective and neuroregenerative agent for ischemic stroke Y Khelif , Ms Quittet , J Toutain , D Divoux , F Sineriz 28th International Symposium on Cerebral Blood Flow, Metabolism and Function & 13th International Conference on Quantification of Brain Function with PET, Apr 2017, Berlin, Germany. pp.106-107 Communication dans un congrès hal-02265376v1
	RGTA is a novel matrix therapy for ischemic stroke Yacine Khelif , Ms Quittet , Jérôme Toutain , Didier Divoux , F Sineriz 21st Annual Meeting of the LARC-Neuroscience network, Oct 2017, Lille, France Communication dans un congrès hal-02304978v1
	A novel ischemic stroke matrix therapy based on the RGTA Y Khelif , Ms Quittet , J Toutain , D Divoux , F Sineriz 2ème Journée Normande de Recherche Biomédicale, JNRB 2017, Nov 2017, Caen, France Communication dans un congrès hal-02269621v1
	Biomedical use of nanosized zeolites for aggressive brain tumors Anfray C. , Goldyn K. , Komaty S. , Allioux C. , Zaarour M. 7th FEZA Conference “The ZEOLITES: Materials with Engineered Properties”, Jul 2017, Sofia, Bulgaria Communication dans un congrès hal-02268071v1
	An analogue of heparan sulfate as a novel neuroprotective and neuroregenerative agent for ischemic stroke Yacine Khelif , Ms Quittet , Toutain Jérôme , Divoux Didier , F Sineriz Brain & Brain PET 2017, Apr 2017, Berlin, Germany Communication dans un congrès hal-02269032v1
	Caractérisation par imagerie multimodale IRM et TEP des métastases cérébrales pour l’adaptation des traitements de radiothérapie A Corroyer-Dulmont , S Valable , J Toutain , D Divoux , M Ibazizène Journée du Cancéropôle Nord-Ouest Axe 3 : "Imagerie Fonctionnelle et Radiothérapie”, Dec 2017, Caen, France Communication dans un congrès hal-02268079v1
	Implication de HAF dans la croissance des glioblastomes : caractérisation in vitro et in vivo G Lambert , E.A. Pérès , K Bordji , D Divoux , J Toutain 10èmes journées scientifiques du Cancéropôle Nord-Ouest, May 2017, Deauville, France Communication dans un congrès hal-02268085v1
	StO2-MRI sensitively images hypoxia in the brain: validation in both ischemic and tumoral situations S Valable , J Toutain , A Corroyer-Dulmont , A Chakhoyan , D Divoux 2ème Congrès National d'Imagerie du Vivant CNIV 2017, Nov 2017, Paris, France Communication dans un congrès hal-02268068v1
	Zeolites: a new theranostic tool for glioblastoma C. Anfray , S. Komaty , C. Allioux , J. Toutain , O. Touzani New chemical and biological tools for targeting in cancer imaging and therapy. Cancéropôle Grand-Ouest international workshop, Sep 2016, Le Bono, France Communication dans un congrès hal-02269683v1
	RGTA-4131®, an analogue of heparan sulfate, is a potential novel protective and regenerative therapy for ischemic stroke Y Khelif , Ms Quittet , J Toutain , D Divoux , F Sineriz Congrès de la section 28 du CNRS « Pharmacologie, Bio-ingenierie, imagerie, biotechnologie », Jun 2016, Bordeaux, France Communication dans un congrès hal-02269678v1
	Etude par IRM multiparamétrique des effets du Carbogène sur la vascularisation et l’oxygénation dans deux modèles de glioblastomes A Chakhoyan , A Corroyer-Dulmont , An Gérault , J Toutain , L Chazaviel Workshop du Cancéropôle Nord-Ouest axe 3 - Imagerie fonctionnelle et radiothérapie, Jan 2016, Lille, France Communication dans un congrès hal-02270581v1
	A novel ischemic stroke matrix therapy based on the RGTA Y Khelif , Ms Quittet , J Toutain , D Divoux , F Sineriz 1ère Journée Normande de Recherche Biomédicale, JNRB 2016, Sep 2016, Rouen, France Communication dans un congrès hal-02270571v1
	Hyperoxic gas-induced changes in two models of glioma: an MRI study to assess blood volume and oxygen saturation in rats. A Chakhoyan , A Corroyer-Dulmont , E Petit , L Chazalviel , J Toutain “New Advances in animal Models and preclinical Imaging for translational Research in Cancerology” Workshop, Sep 2015, La Pointe de Pen Bron, France Communication dans un congrès hal-02270583v1
	Apport de l’imagerie multimodale IRM et TEP dans la caractérisation précoce de l’efficacité du Bevacizumab combiné ou non au témozolomide dans un modèle de GBM humain de récidive tumorale A Corroyer-Dulmont , A Gerault , E.A. Pérès , A Savina , J Toutain 2ème Congrès de la Société Française de Résonance Magnétique en Biologie et Médecine, SFRMBM, Mar 2015, Grenoble, France Communication dans un congrès hal-02270627v1
	Multimodal imaging reveals [18F]-FLT-PET as a specific and early readout of temozolomide combined with Bevacizumab response in a recurrent glioblastoma model. A Corroyer-Dulmont , E.A. Pérès , An Gerault , A Savina , J Toutain 3rd Nuclear Technologies for Health Symposium, Mar 2015, Nantes, France Communication dans un congrès hal-02271935v1

jerome toutain

Présentation

Publications

Hypoxia-induced activation of NDR2 underlies brain metastases from Non-Small Cell Lung Cancer

Physical Activity Attenuates Brain Irradiation-Associated Skeletal Muscle Damage in the Rat

Assessment of hypoxia and oxidative-related changes in a lung-derived brain metastasis model by [64Cu][Cu(ATSM)] PET and proteomic studies

Magnetic resonance imaging of hypoxia in acute stroke: a cross‐validation study against FMISO‐positron emission tomography

Multimodal evaluation of hypoxia in brain metastases of lung cancer and interest of hypoxia image-guided radiotherapy

Impact of Hypoxia on Carbon Ion Therapy in Glioblastoma Cells: Modulation by LET and Hypoxia-Dependent Genes

Nanosized zeolites as a gas delivery platform in a glioblastoma model

64Cu-ATSM/64Cu-Cl2 and their relationship to hypoxia in glioblastoma: a preclinical study

VCAM-1 Targeted Alpha-Particle Therapy for Early Brain Metastases

Assessment of behavioural deficits following ischaemic stroke in the marmoset

A heparan sulfate-based matrix therapy reduces brain damage and enhances functional recovery following stroke

Imaging of brain oxygenation with magnetic resonance imaging : A validation with positron emission tomography in the healthy and tumoural brain.

Pharmacological inhibition of myostatin improves skeletal muscle mass and function in a mouse model of stroke

Carbogen-induced increases in tumor oxygenation depend on the vascular status of the tumor: A multiparametric MRI study in two rat glioblastoma models.

Multimodal imaging based on MRI and PET reveals [(18)F]FLT PET as a specific and early indicator of treatment efficacy in a preclinical model of recurrent glioblastoma

Chronic arterial hypertension impedes glioma growth: a multiparametric MRI study in the rat.

Effects of mesenchymal stem cell therapy, in association with pharmacologically active microcarriers releasing VEGF, in an ischaemic stroke model in the rat.

Silencing erythropoietin receptor on glioma cells reinforces efficacy of temozolomide and X-rays through senescence and mitotic catastrophe

Molecular mechanisms of skeletal muscle atrophy in a mouse model of cerebral ischemia

Detection of glioblastoma response to temozolomide combined with bevacizumab based on µMRI and µPET imaging reveals [$^{18}$F]-fluoro-L-thymidine as an early and robust predictive marker for treatment efficacy

Noninvasive assessment of hypoxia with 3-[18F]-fluoro-1-(2-nitro-1-imidazolyl)-2-propanol ([18F]-FMISO): a PET study in two experimental models of human glioma

Maternal hypertension during pregnancy modifies the response of the immature brain to hypoxia-ischemia: sequential MRI and behavioral investigations.

The adhesive removal test: a sensitive method to assess sensorimotor deficits in mice.

Delayed hypoxic postconditioning protects against cerebral ischemia in the mouse.

Combined therapeutic strategy using erythropoietin and mesenchymal stem cells potentiates neurogenesis after transient focal cerebral ischemia in rats.

Expression of the gene encoding the pro-apoptotic BNIP3 protein and stimulation of hypoxia-inducible factor-1alpha (HIF-1alpha) protein following focal cerebral ischemia in rats

Preclinical model of radiation induced-neurotoxicity: longitudinal and multiparametric evaluation of tissue injury and cognitive deficits in the rat

Hadrontherapy to target glioblastoma stem cells to overcome radioresistance

Etude préclinique de l'hypoxie tumorale par imagerie multimodale en IRM et TEP dans les métastases cérébrales : intérêt du [64Cu]-ATSM ?

Preclinical model of radiation induced-neurotoxicity: longitudinal and multiparametric evaluation of tissue injury and cognitive deficits in the rat

The physical activity attenuates the brain irradiation-induced cerebral and skeletal muscle injuries in the adult rat

The whole-brain irradiation induces skeletal muscle damage in the rat

Preclinical model of radiation induced-neurotoxicity: longitudinal and multiparametric evaluation of tissue injury and cognitive deficits in the rat

Etude préclinique de l’hypoxie tumorale par imagerie multimodale en IRM et TEP dans les métastases cérébrales : intérêt du [64Cu]-ATSM ?

MRI biomarkers for the detection of radiation-induced brain injury associated to cognitive deficits

Overcoming hypoxia-induced radioresistance of glioblastoma cells by hadrontherapy

L’activité physique réduit la cachexie observée après irradiation cérébrale chez le rat

Development and in vivo preclinical validation of [18F]FLUSONIM, a highly hydrophilic 18F-labelled 2-nitroimidazole derivative for high performance hypoxia PET imaging

Early brain metastases treatment using VCAM-1 targeted alpha-particle therapy

Relevance of multiparametric MRI to accurately detect radiation-induced brain injury in the rat

Evaluation préclinique de l’influence d'anesthésiques intraveineux sur les cellules de glioblastome et l’efficacité des traitements par chimio- et radiothérapie

VCAM-1 targeted alpha-particle therapy for early brain metastases

Hypoxia image-Guided Radiotherapy for the treatment of brain metastases from primary lung cancer, a preclinical study.

Evaluation par IRM des dommages cérébraux induits par la radiothérapie dans un modèle de rat

VCAM-1 targeted alpha-particle therapy for early brain metastases

Etude multiparamétrique des effets de l'irradiation cérébrale chez le rat : des altérations tissulaires jusqu'aux déficits cognitifs

A combination of stem cells and an extracellular matrix agent as a new therapeutic strategy for ischemic stroke

Evaluation des dommages cérébraux radio-induits par l’exposition à de faibles et fortes doses de rayonnements ionisants sur un modèle de rat adulte

Développement et validation préclinique in vivo du [18F]FLUSONIM pour l’imagerie TEP de l’hypoxie de haute performance

Hypoxia imaging: interest of Image-Guided Radiotherapy for the treatment of brain metastases from lung cancer, a preclinical study

Hypoxia imaging: interest of Image-Guided Radiotherapy for the treatment of brain metastases from lung cancer, a preclinical study

Heparan sulfate mimetics are neuroprotective and neuroregenerative agents for ischemic stroke.

An analogue of heparan sulfate as a novel neuroprotective and neuroregenerative agent for ischemic stroke

RGTA is a novel matrix therapy for ischemic stroke

A novel ischemic stroke matrix therapy based on the RGTA

Biomedical use of nanosized zeolites for aggressive brain tumors

An analogue of heparan sulfate as a novel neuroprotective and neuroregenerative agent for ischemic stroke

Caractérisation par imagerie multimodale IRM et TEP des métastases cérébrales pour l’adaptation des traitements de radiothérapie

Implication de HAF dans la croissance des glioblastomes : caractérisation in vitro et in vivo

StO2-MRI sensitively images hypoxia in the brain: validation in both ischemic and tumoral situations

Zeolites: a new theranostic tool for glioblastoma

RGTA-4131®, an analogue of heparan sulfate, is a potential novel protective and regenerative therapy for ischemic stroke

Etude par IRM multiparamétrique des effets du Carbogène sur la vascularisation et l’oxygénation dans deux modèles de glioblastomes

A novel ischemic stroke matrix therapy based on the RGTA

Hyperoxic gas-induced changes in two models of glioma: an MRI study to assess blood volume and oxygen saturation in rats.

Apport de l’imagerie multimodale IRM et TEP dans la caractérisation précoce de l’efficacité du Bevacizumab combiné ou non au témozolomide dans un modèle de GBM humain de récidive tumorale

Multimodal imaging reveals [18F]-FLT-PET as a specific and early readout of temozolomide combined with Bevacizumab response in a recurrent glioblastoma model.