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Acylation determines the toll-like receptor (TLR)-dependent positive versus TLR2-, mannose receptor-, and SIGNR1-independent negative regulation of pro-inflammatory cytokines by mycobacterial lipomannan.

Emilie Doz , Stéphanie Rose , Jérôme Nigou , Martine Gilleron , Germain Puzo , et al.
Journal of Biological Chemistry, 2007, 282 (36), pp.26014-25. ⟨10.1074/jbc.M702690200⟩
Article dans une revue hal-00318491v1
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Disruption of the SucT acyltransferase in Mycobacterium smegmatis abrogates succinylation of cell envelope polysaccharides

Zuzana Palčeková , Shiva Angala , Juan Manuel Belardinelli , Haig Eskandarian , Maju Joe , et al.
Journal of Biological Chemistry, 2019, 294 (26), pp.10325-10335. ⟨10.1074/jbc.RA119.008585⟩
Article dans une revue hal-02325319v1

AftD, a novel essential arabinofuranosyltransferase from mycobacteria

Henrieta Škovierová , Gerald Larrouy-Maumus , Jian Zhang , Devinder Kaur , Nathalie Barilone , et al.
Glycobiology, 2009, 19 (11), pp.1235-1247. ⟨10.1093/glycob/cwp116⟩
Article dans une revue hal-03177973v1

Mycobacterial lipoarabinomannans: modulators of dendritic cell function and the apoptotic response.

Jérôme Nigou , Martine Gilleron , Mauricio Rojas , Luis F García , Martin Thurnher , et al.
Microbes and Infection, 2002, 4 (9), pp.945-53
Article dans une revue hal-00177974v1
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Structural and functional analysis of the Francisella lysine decarboxylase as a key actor in oxidative stress resistance

Jan Felix , Claire Siebert , Juila Novion Ducassou , Jérôme Nigou , Pierre Simon Garcia , et al.
Scientific Reports, 2021, 11 (1), pp.972. ⟨10.1038/s41598-020-79611-5⟩
Article dans une revue hal-03118173v1

Mannodendrimers prevent acute lung inflammation by inhibiting neutrophil recruitment

Emilyne Blattes , Alain Vercellone , Hélène Eutamène , Cédric-Olivier Turrin , Vassilia Theodorou , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2013, 110 (22), pp.8795-8800. ⟨10.1073/pnas.1221708110⟩
Article dans une revue hal-00994589v1

The acylation state of mycobacterial lipomannans modulates innate immunity response through toll-like receptor 2.

Martine Gilleron , Jérôme Nigou , Delphine Nicolle , Valérie Quesniaux , Germain Puzo
Chemistry & Biology / Chemistry and Biology; CHEMISTRY & BIOLOGY, 2006, 13 (1), pp.39-47. ⟨10.1016/j.chembiol.2005.10.013⟩
Article dans une revue hal-00177665v1
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A Small Multidrug Resistance-like Transporter Involved in the Arabinosylation of Arabinogalactan and Lipoarabinomannan in Mycobacteria*

Gerald Larrouy-Maumus , Henrieta Škovierová , Rabeb Dhouib , Shiva Kumar Angala , Sophie Zuberogoitia , et al.
Journal of Biological Chemistry, 2012, 287 (47), pp.39933-39941. ⟨10.1074/jbc.M112.400986⟩
Article dans une revue hal-03178003v1

Lipoarabinomannans: from structure to biosynthesis.

Jérôme Nigou , Martine Gilleron , Germain Puzo
Biochimie, 2003, 85 (1-2), pp.153-66
Article dans une revue hal-00177973v1
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The lipid virulence factors of Mycobacterium tuberculosis exert multilayered control over autophagy-related pathways in infected human macrophages

Aïcha Bah , Merlin Sanicas , Jérôme Nigou , Christophe Guilhot , Catherine Astarie-Dequeker , et al.
eSymposia Keystone, Oct 2020, Kerry, Ireland
Poster de conférence hal-03382295v1
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A TLR2-Activating Fraction From Mycobacterium abscessus Rough Variant Demonstrates Vaccine and Diagnostic Potential

Vincent Le Moigne , Anne-Laure Roux , Aude Jobart-Malfait , Landry Blanc , Karima Chaoui , et al.
Frontiers in Cellular and Infection Microbiology, 2020, 10, ⟨10.3389/fcimb.2020.00432⟩
Article dans une revue hal-03031741v1

Mycobacterium marinum MMAR_2380, a predicted transmembrane acyltransferase, is essential for the presence of the mannose cap on lipoarabinomannan

Nicole Driessen , Esther Stoop , Roy Ummels , Sudagur Gurcha , Arun Mishra , et al.
Microbiology, 2010, 156 (11), pp.3492-3502. ⟨10.1099/mic.0.037507-0⟩
Article dans une revue hal-03177979v1
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Plasma LOX-Products and Monocyte Signaling Is Reduced by Adjunctive Cyclooxygenase-2 Inhibitor in a Phase I Clinical Trial of Tuberculosis Patients

Marthe Jøntvedt Jørgensen , Kristin Nore , Hans Christian D. Aass , Emilie Layre , Jérôme Nigou , et al.
Frontiers in Cellular and Infection Microbiology, 2021, 11, pp.669623. ⟨10.3389/fcimb.2021.669623⟩
Article dans une revue hal-03445397v1

Biosynthetic Origin of the Galactosamine Substituent of Arabinogalactan in Mycobacterium tuberculosis*

Henrieta Škovierová , Gerald Larrouy-Maumus , Ha Pham , Martina Belanová , Nathalie Barilone , et al.
Journal of Biological Chemistry, 2010, 285 (53), pp.41348-41355. ⟨10.1074/jbc.M110.188110⟩
Article dans une revue hal-03177982v1

Identification of a novel mannose-capped lipoarabinomannan from Amycolatopsis sulphurea

Kevin Gibson , Martine Gilleron , Patricia Constant , Germain Puzo , Jérôme Nigou , et al.
Biochemical Journal, 2003, 372 (3), pp.821-829. ⟨10.1042/BJ20030197⟩
Article dans une revue hal-03177850v1

Mannan Chain Length Controls Lipoglycans Signaling via and Binding to TLR2

Jérôme Nigou , Thierry Vasselon , Aurélie Ray , Patricia Constant , Martine Gilleron , et al.
Journal of Immunology, 2008, 180 (10), pp.6696-6702. ⟨10.4049/jimmunol.180.10.6696⟩
Article dans une revue hal-03177926v1
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Development of a novel target-based cell assay, reporter of the activity of Mycobacterium tuberculosis protein- O -mannosyltransferase

Nicolas Géraud , Camille Falcou , Julien Parra , Carine Froment , David Rengel , et al.
Glycobiology, 2023, ⟨10.1093/glycob/cwad072⟩
Article dans une revue hal-04264267v1

Identification of an ?(1?6) mannopyranosyltransferase (MptA), involved in Corynebacterium glutamicum lipomanann biosynthesis, and identification of its orthologue in Mycobacterium tuberculosis

Arun Mishra , Luke Alderwick , Doris Rittmann , Raju Tatituri , Jérôme Nigou , et al.
Molecular Microbiology, 2007, 65 (6), pp.1503-1517. ⟨10.1111/j.1365-2958.2007.05884.x⟩
Article dans une revue hal-03177909v1
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Rational design of adjuvants targeting the C-type lectin Mincle

Alexiane Decout , Sandro Silva-Gomes , Daniel Drocourt , Sophie Barbe , Isabelle André , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (10), pp.2675-2680. ⟨10.1073/pnas.1612421114⟩
Article dans une revue hal-01607936v1

Structural analysis of mycobacterial lipoglycans.

Jérôme Nigou , Martine Gilleron , Thérèse Brando , Germain Puzo
Applied Biochemistry and Biotechnology, 2004, 118 (1-3), pp.253-67
Article dans une revue hal-00177964v1
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Lipoglycans Contribute to Innate Immune Detection of Mycobacteria

Shyam Krishna , Aurélie Ray , Shiv Dubey , Gerald Larrouy-Maumus , Christian Chalut , et al.
PLoS ONE, 2011, 6 (12), pp.e28476. ⟨10.1371/journal.pone.0028476⟩
Article dans une revue hal-02391864v1

Mycobacterium tuberculosis inhibits human innate immune responses via the production of TLR2 antagonist glycolipids

Landry Blanc , Martine Gilleron , Jacques Prandi , Ok-Ryul Song , Mi-Seon Jang , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (42), pp.11205-11210. ⟨10.1073/pnas.1707840114⟩
Article dans une revue hal-03178071v1
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Potential Plasticity of the Mannoprotein Repertoire Associated to Mycobacterium tuberculosis Virulence Unveiled by Mass Spectrometry-Based Glycoproteomics

Laure Tonini , Bashir Sadet , Alexandre Stella , David Bouyssié , Jérôme Nigou , et al.
Molecules, 2020, 25 (10), pp.2348. ⟨10.3390/molecules25102348⟩
Article dans une revue hal-03032960v1

Lipoteichoic Acid in Streptomyces hygroscopicus: Structural Model and Immunomodulatory Activities

Marlène Cot , Aurélie Ray , Martine Gilleron , Alain Vercellone , Gerald Larrouy-Maumus , et al.
PLoS ONE, 2011, 6 (10), pp.e26316. ⟨10.1371/journal.pone.0026316⟩
Article dans une revue hal-03177994v1

Deciphering the molecular bases of Mycobacterium tuberculosis binding to the lectin DC-SIGN reveals an underestimated complexity.

Sylvain Pitarque , Jean-Louis Herrmann , Jean-Luc Duteyrat , Mary Jackson , Graham R Stewart , et al.
Biochemical Journal, 2005, 392 (Pt 3), pp.615-24. ⟨10.1042/BJ20050709⟩
Article dans une revue pasteur-01372648v1

Acylation Determines the Toll-like receptor (TLR)-dependent Positive Versus TLR2-, Mannose Receptor-, and SIGNR1-independent Negative Regulation of Pro-inflammatory Cytokines by Mycobacterial Lipomannan

Emilie Doz , Stéphanie Rose , Jérôme Nigou , Martine Gilleron , Germain Puzo , et al.
Journal of Biological Chemistry, 2007, 282 (36), pp.26014-26025. ⟨10.1074/jbc.M702690200⟩
Article dans une revue hal-03177915v1
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Rv0180c contributes to Mycobacterium tuberculosis cell shape and to infectivity in mice and macrophages

Delphine Payros , Henar Alonso , Wladimir Malaga , Arnaud Volle , Serge Mazères , et al.
PLoS Pathogens, 2021, 17 (11), pp.e1010020. ⟨10.1371/journal.ppat.1010020⟩
Article dans une revue hal-03420756v1
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Scrutiny of Mycobacterium tuberculosis 19 kDa antigen proteoforms provides new insights in the lipoglycoprotein biogenesis paradigm

Julien Parra , Julien Marcoux , Isabelle Poncin , Stéphane Canaan , Jean Louis Herrmann , et al.
Scientific Reports, 2017, 7, pp.43682. ⟨10.1038/srep43682⟩
Article dans une revue hal-01791689v1

Overexpression of proinflammatory TLR-2-signalling lipoproteins in hypervirulent mycobacterial variants

Anne-Laure Roux , Aurélie Ray , Alexandre Pawlik , Halima Medjahed , Gilles Etienne , et al.
Cellular Microbiology, 2011, 13 (5), pp.692-704. ⟨10.1111/j.1462-5822.2010.01565.x⟩
Article dans une revue pasteur-02618829v1
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The Lipid Virulence Factors of Mycobacterium tuberculosis Exert Multilayered Control over Autophagy-Related Pathways in Infected Human Macrophages

Aïcha Bah , Merlin Sanicas , Jérôme Nigou , Christophe Guilhot , Catherine Astarie-Dequeker , et al.
Cells, 2020, 9 (3), pp.666. ⟨10.3390/cells9030666⟩
Article dans une revue hal-02650295v1