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Lipid Metabolism and Resistance to Anticancer Treatment

 Nicolas Germain , Mélanie Dhayer , Marie Boileau , Quentin Fovez , Jerome Kluza , et al.
Biology, 2020, 9 (12), pp.474. ⟨10.3390/biology9120474⟩
Article dans une revue hal-04540682v1
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Increased CD271 expression by the NF-kB pathway promotes melanoma cell survival and drives acquired resistance to BRAF inhibitor vemurafenib

 Abdelali Lehraiki , Michaël Cerezo , Florian Rouaud , Patricia Abbe , Marilyne Allegra , et al.
Cell Discovery, 2015, 1, pp.15030. ⟨10.1038/celldisc.2015.30⟩
Article dans une revue inserm-02530554v1
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First-line Screening of OXPHOS Deficiencies Using Microscale Oxygraphy in Human Skin Fibroblasts: A Preliminary Study

 Nicolas Germain , Anne-Frédérique Dessein , Jean-Claude Vienne , Dries Dobbelaere , Karine Mention , et al.
International Journal of Medical Sciences, 2019, 16 (7), pp.931-938. ⟨10.7150/ijms.32413⟩
Article dans une revue hal-02913827v1

Antimetabolic cooperativity with the clinically approved l-asparaginase and tyrosine kinase inhibitors to eradicate CML stem cells

 Anne Trinh , Raeeka Khamari , Quentin Fovez , François-Xavier Mahon , Béatrice Turcq , et al.
Molecular metabolism, 2022, 55, pp.101410. ⟨10.1016/j.molmet.2021.101410⟩
Article dans une revue hal-04540675v1

Metabolic rewiring in cancer cells overexpressing the glucocorticoid-induced leucine zipper protein (GILZ): Activation of mitochondrial oxidative phosphorylation and sensitization to oxidative cell death induced by mitochondrial targeted drugs

 Fanny André , Anne Trinh , Stéphane Balayssac , Patrice Maboudou , Salim Dekiouk , et al.
International Journal of Biochemistry and Cell Biology, 2017, 85, pp.166-174. ⟨10.1016/j.biocel.2017.02.011⟩
Article dans une revue hal-02060241v1

Lactate Inhibits the Pro-Inflammatory Response and Metabolic Reprogramming in Murine Macrophages in a GPR81-Independent Manner.

 Agustina Errea , Delphine Cayet , Philippe Marchetti , Cong Tang , Jerome Kluza , et al.
PLoS ONE, 2016, 11 (11), pp.e0163694. ⟨10.1371/journal.pone.0163694⟩
Article dans une revue inserm-01529298v1
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Mitochondrial alterations triggered by repeated exposure to fine (PM2.5-0.18) and quasi-ultrafine (PM0.18) fractions of ambient particulate matter

 J. Sotty , J. Kluza , C. de Sousa , M. Tardivel , S. Antherieu , et al.
Environment International, 2020, 142, pp.105830. ⟨10.1016/j.envint.2020.105830⟩
Article dans une revue hal-02913607v1

Inactivation of the HIF-1 /PDK3 Signaling Axis Drives Melanoma toward Mitochondrial Oxidative Metabolism and Potentiates the Therapeutic Activity of Pro-Oxidants

 J. Kluza , P. Corazao-Rozas , Y. Touil , M. Jendoubi , C. Maire , et al.
Cancer Research, 2012, 72 (19), pp.5035 - 5047. ⟨10.1158/0008-5472.CAN-12-0979⟩
Article dans une revue hal-01853694v1
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p65/RelA NF‐κB fragments generated by RIPK3 activity regulate tumorigenicity, cell metabolism, and stemness characteristics

 Yasmine Touil , Céline Latreche‐carton , Hassiba El Bouazzati , Anne‐lucie Nugues , Nathalie Jouy , et al.
Journal of Cellular Biochemistry, 2022, 123 (3), pp.543-556. ⟨10.1002/jcb.30198⟩
Article dans une revue hal-03641788v1

Mitochondrial inhibitors circumvent adaptive resistance to venetoclax and cytarabine combination therapy in acute myeloid leukemia

 Claudie Bosc , Estelle Saland , Aurélie Bousard , Noémie Gadaud , Marie Sabatier , et al.
Nature Cancer, 2021, 2 (11), pp.1204-1223. ⟨10.1038/s43018-021-00264-y⟩
Article dans une revue hal-03565962v1

Clinically Relevant Oxygraphic Assay to Assess Mitochondrial Energy Metabolism in Acute Myeloid Leukemia Patients

 Quentin Fovez , William Laine , Laure Goursaud , Celine Berthon , Nicolas Germain , et al.
Cancers, 2021, 13 (24), pp.6353. ⟨10.3390/cancers13246353⟩
Article dans une revue hal-04540662v1
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M‐CSF‐mediated macrophage development is dominantly inhibited by NOD2 signaling for replenishment of immunogenic dendritic cells

 Camille Chauvin , Daniel Alvarez-Simon , Paul Régnier , Katarina Radulovic , Olivier Boulard , et al.
6th European Congress of Immunology, Sep 2021, Belgrade, Serbia. 51, pp.307, P‐0672. ⟨10.1002/eji.202170200⟩
Poster de conférence hal-03870668v1
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TRPC3 shapes the ER-mitochondria Ca2+ transfer characterizing tumour-promoting senescence

 Valerio Farfariello , Dmitri Gordienko , Lina Mesilmany , Yasmine Touil , Emmanuelle Germain , et al.
Nature Communications, 2022, 13 (1), pp.956. ⟨10.1038/s41467-022-28597-x⟩
Article dans une revue hal-03666578v1

Energy metabolism alteration and anticancer treatment: study of a troglitazone derivative in triple-negative breast cancer cells

 Claire Muller , Stéphanie Grandemange , Jerome Kluza , Frédéric Bost , Eline Piquard , et al.
Cancer and Metabolism 2018, Jun 2018, Cambridge, United Kingdom
Communication dans un congrès hal-01946195v1

A new derivative of troglitazone affects energy metabolism of triple negative breast cancer cells: potential interest for anticancer treatment

 Claire Muller , Stéphanie Grandemange , Jerome Kluza , Frédéric Bost , Eline Piquard , et al.
11ème Forum du Cancéropôle Est, Nov 2018, Reims, France
Communication dans un congrès hal-01937228v1
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Antimetabolic cooperativity with the clinically approved kidrolase and tyrosine kinase inhibitors to eradicate cml stem cells

 Anne Trinh , Raeeka Khamari , Quentin Fovez , François-Xavier Mahon , Béatrice Turcq , et al.
Molecular metabolism, 2022, 55, pp.101410. ⟨10.1016/j.molmet.2021.101410⟩
Article dans une revue hal-03086546v2
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Comparison of the in vivo genotoxicity of electronic and conventional cigarettes aerosols after subacute, subchronic and chronic exposures

 Anne Platel , Romain Dusautoir , Gwenola Kervoaze , Gonzague Dourdin , Eulalie Gateau , et al.
Journal of Hazardous Materials, 2022, Journal of Hazardous Materials, 423, pp.127246. ⟨10.1016/j.jhazmat.2021.127246⟩
Article dans une revue hal-03895890v1
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Cigarette smoke alters the ability of human dendritic cells to promote anti-Streptococcus pneumoniae Th17 response

 Olivier Le Rouzic , Bachirou Koné , Jerome Kluza , Philippe Marchetti , Florence Hennegrave , et al.
Respiratory Research, 2015, 17 (1), pp.94. ⟨10.1186/s12931-016-0408-6⟩
Article dans une revue inserm-01349118v1
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Glucose metabolism and NRF2 coordinate the antioxidant response in melanoma resistant to MAPK inhibitors

 Raeeka Khamari , Anne Trinh , Pierre Elliott Gabert , Paola Corazao-Rozas , Samuel Riveros-Cruz , et al.
Cell Death and Disease, 2018, 9 (3), pp.325. ⟨10.1038/s41419-018-0340-4⟩
Article dans une revue hal-02058739v1
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Another Facet to the Anticancer Response to Lamellarin D: Induction of Cellular Senescence through Inhibition of Topoisomerase I and Intracellular Ros Production

 Caroline Ballot , Alain Martoriati , Manel Jendoubi , Sébastien Buche , Pierre Formstecher , et al.
Marine drugs, 2014, 12 (2), pp.779-798. ⟨10.3390/md12020779⟩
Article dans une revue hal-03167877v1
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A New Strategy to Preserve and Assess Oxygen Consumption in Murine Tissues

 Jerome Kluza , Victoriane Peugnet , Blanche Daunou , William Laine , Gwenola Kervoaze , et al.
International Journal of Molecular Sciences, 2021, 23 (1), pp.109. ⟨10.3390/ijms23010109⟩
Article dans une revue hal-03531236v1

M-CSF-mediated macrophage development is dominantly inhibited by NOD2 signaling for replenishment of immunogenic dendritic cells

 Camille Chauvin , Daniel Alvarez-Simon , Paul Regnier , Katarina Radulovic , Olivier Boulard , et al.
6th European Congress of Immunology (ECI), Apr 2021, Virtually, France. pp.307/P-0672
Communication dans un congrès hal-04543258v1

Mitochondrial adaptation decreases drug sensitivity of persistent triple negative breast cancer cells surviving combinatory and sequential chemotherapy

 Marie Winter , Amina Nait Eldjoudi , Catherine Guette , Hubert Hondermarck , Roland Bourette , et al.
Neoplasia, 2023, 46, pp.100949. ⟨10.1016/j.neo.2023.100949⟩
Article dans une revue hal-04281090v1
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Extracellular vesicles derived from nasopharyngeal carcinoma induce the emergence of mature regulatory dendritic cells using a galectin-9 dependent mechanism.

 A. Lefebvre , Camille Trioen , Renaud Silvestri , William Laine , Benjamin Hennart , et al.
Journal of extracellular vesicles, 2023, Journal of extracellular vesicles, 12 (12), pp.e12390. ⟨10.1002/jev2.12390⟩
Article dans une revue hal-04474720v1

Air pollution-derived PM2.5 impairs mitochondrial function in healthy and chronic obstructive pulmonary diseased human bronchial epithelial cells

 B. Leclercq , J. Kluza , S. Antherieu , J. Sotty , L.Y. Alleman , et al.
Environmental Pollution, 2018, 243, pp.1434-1449. ⟨10.1016/j.envpol.2018.09.062⟩
Article dans une revue hal-02552778v1

Antimetabolic cooperativity with the clinically approved l-asparaginase and tyrosine kinase inhibitors to eradicate CML stem cells

 Anne Trinh , Raeeka Khamari , Quentin Fovez , François-Xavier Mahon , Béatrice Turcq , et al.
Molecular metabolism, 2022, 55, pp.101410. ⟨10.1016/j.molmet.2021.101410⟩
Article dans une revue hal-03867553v1
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