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Estrogen Receptor Transcriptional Activity: A Dynamic Integration of Multi-Leveled Information.

S. Cunha , J. Quintin , Aurélien Sérandour , Vincent Legagneux , Gaëlle Palierne , et al.
Keystone Symposia on Nuclear Receptors: Signaling, Gene Regulation and Cancer, Mar 2010, Keystone, United States
Communication dans un congrès hal-00493914v1
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An extended transcription factor regulatory network controls hepatocyte identity

Julie Dubois‐chevalier , Céline Gheeraert , Alexandre Berthier , Clémence Boulet , Vanessa Dubois , et al.
EMBO Reports, 2023, ⟨10.15252/embr.202357020⟩
Article dans une revue hal-04169341v1
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Nuclear Receptor Subfamily 1 Group D Member 1 Regulates Circadian Activity Of NLRP3 Inflammasome to Reduce the Severity of Fulminant Hepatitis in Mice

Benoit Pourcet , Mathilde Zecchin , Lise Ferri , Justine Beauchamp , Sadichha Sitaula , et al.
Gastroenterology, 2018, Gastroenterology, 154 (5), pp.1449-1464. ⟨10.1053/j.gastro.2017.12.019⟩
Article dans une revue inserm-01701933v1
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Endoplasmic reticulum stress actively suppresses hepatic molecular identity in damaged liver

Vanessa Dubois , Celine Gheeraert , Wouter Vankrunkelsven , Julie Dubois‐chevalier , Hélène Dehondt , et al.
Molecular Systems Biology, 2020, 16 (5), pp.e9156. ⟨10.15252/msb.20199156⟩
Article dans une revue inserm-02617039v1

Roux-en-Y gastric bypass induces hepatic transcriptomic signatures and plasma metabolite changes indicative of improved cholesterol homeostasis.

Fanny Lalloyer , Denis A. Mogilenko , Ann Verrijken , Joël T. Haas , Antonin Lamaziere , et al.
Journal of hepatology, 2023, J Hepatol, ⟨10.1016/j.jhep.2023.05.012⟩
Article dans une revue hal-04197486v1
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The HDAC inhibitor trichostatin A impairs pancreatic b-cell function through an epigenome-wide reprogramming

Frédérik Oger , Maeva Moreno , Mehdi Derhourhi , Bryan Thiroux , Lionel Berberian , et al.
2023
Pré-publication, Document de travail hal-04365596v1
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The logic of transcriptional regulator recruitment architecture at cis-regulatory modules controlling liver functions

Julie Dubois , Vanessa Dubois , Hélène Dehondt , Parisa Mazrooei , Claire Mazuy , et al.
Genome Research, 2017, Genome research, 27 (6), pp.985-996. ⟨10.1101/gr.217075.116⟩
Article dans une revue hal-01647846v1
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PERSPECTIVES ON THE USE OF SUPER-ENHANCERS AS A DEFINING FEATURE OF CELL/TISSUE- IDENTITY GENES

Julie Dubois-Chevalier , Vanessa Dubois , Bart Staels , Philippe Lefebvre , Jérôme Eeckhoute
Epigenomics, 2020, 12, pp.715-723
Article dans une revue inserm-02506724v1
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Hepatic molecular signatures highlight the sexual dimorphism of Non-Alcoholic SteatoHepatitis (NASH)

Jimmy Vandel , Julie Dubois-Chevalier , Celine Gheeraert , Bruno Derudas , Violetta Raverdy , et al.
Hepatology, 2020, ⟨10.1002/HEP.31312⟩
Article dans une revue inserm-02617094v1
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Retinoids Issued from Hepatic Stellate Cell Lipid Droplet Loss as Potential Signaling Molecules Orchestrating a Multicellular Liver Injury Response

Marie Bobowski-Gerard , Francesco Paolo Zummo , Bart Staels , Jérôme Eeckhoute
Cells, 2018, 7 (9), pii: E137. ⟨10.3390/cells7090137⟩
Article dans une revue inserm-02154783v1

Human Alternative Macrophages Populate Calcified Areas of Atherosclerotic Lesions and Display Impaired RANKL-Induced Osteoclastic Bone Resorption Activity

Giulia Chinetti-Gbaguidi , Mehdi Daoudi , Mickael Rosa , Manjula Vinod , Loïc Louvet , et al.
Circulation Research, 2017, 121 (1), pp.19-30. ⟨10.1161/CIRCRESAHA.116.310262⟩
Article dans une revue hal-03955455v1

Inactivation of the Nuclear Orphan Receptor COUP-TFII by Small Chemicals

Rémy Le Guével , Frederik Oger , Celia P. Martinez-Jimenez , Maud Bizot , Celine Gheeraert , et al.
ACS Chemical Biology, 2017, 12 (3), pp.654-663. ⟨10.1021/acschembio.6b00593⟩
Article dans une revue hal-01497231v1
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Maternal obesity programs increased leptin gene expression in rat male offspring via epigenetic modifications in a depot-specific manner

Simon Lecoutre , Frederik Oger , Charlène Pourpe , Laura Butruille , Lucie Marousez , et al.
Molecular metabolism, 2017, 6 (8), pp.922-930. ⟨10.1016/j.molmet.2017.05.010⟩
Article dans une revue hal-01607373v1
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Combinatorial regulation of hepatic cytoplasmic signaling and nuclear transcriptional events by the OGT/REV-ERBα complex

Alexandre Berthier , Manjula Vinod , Geoffrey Porez , Agata Steenackers , Jérémy Alexandre , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (47), pp.11033-11042. ⟨10.1073/pnas.1805397115⟩
Article dans une revue inserm-01924835v1
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Coordinated Regulation of PPARγ Expression and Activity through Control of Chromatin Structure in Adipogenesis and Obesity.

Jérôme Eeckhoute , Frédérik Oger , Bart Staels , Philippe Lefebvre
PPAR Research, 2012, 2012, pp.164140. ⟨10.1155/2012/164140⟩
Article dans une revue inserm-00734330v1

Epigenetic switch involved in activation of pioneer factor FOXA1-dependent enhancers.

Aurélien A. Sérandour , Stéphane Avner , Frédéric Percevault , Florence Demay , Maud Bizot , et al.
Genome Research, 2011, 21 (4), pp.555-65. ⟨10.1101/gr.111534.110⟩
Article dans une revue hal-00587841v1

Defining specificity of transcription factor regulatory activities.

Jérôme Eeckhoute , Raphaël Métivier , Gilles Salbert
Journal of Cell Science, 2009, 122 (Pt 22), pp.4027-34. ⟨10.1242/jcs.054916⟩
Article dans une revue hal-00436576v1
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An extended transcription factor regulatory network involving stabilization loops controls hepatocyte identity

Julie Dubois-Chevalier , Céline Gheeraert , Alexandre Berthier , Clémence Boulet , Vanessa Dubois , et al.
2023
Pré-publication, Document de travail hal-04137074v1
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Dynamic hydroxymethylation of deoxyribonucleic acid marks differentiation-associated enhancers.

Aurélien A. Sérandour , Stéphane Avner , Frédérik Oger , Maud Bizot , Frédéric Percevault , et al.
Nucleic Acids Research, 2012, 40 (17), pp.8255-65. ⟨10.1093/nar/gks595⟩
Article dans une revue inserm-00716879v1
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Time-of-day-dependent variation of the human liver transcriptome and metabolome is disrupted in MASLD

Manuel Johanns , Joel T Haas , Violetta Raverdy , Jimmy Vandel , Julie Chevalier-Dubois , et al.
JHEP Reports, In press, 6 (1), pp.100948. ⟨10.1016/j.jhepr.2023.100948⟩
Article dans une revue hal-04264177v1
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A time- and space-resolved nuclear receptor atlas in mouse liver

Francesco Paolo Zummo , Alexandre Berthier , Céline Gheeraert , Manjula Vinod , Marie Bobowski-Gérard , et al.
Journal of Molecular Endocrinology, 2023, ⟨10.1530/JME-23-0017⟩
Article dans une revue inserm-04053458v1
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Dynamic ER Interactomes Control the Estrogen-Responsive Trefoil Factor (TFF) Locus Cell-Specific Activities.

Justine Quintin , Christine Le Péron , Gaëlle Palierne , Maud Bizot , Stéphanie Cunha , et al.
Molecular and Cellular Biology, 2014, 34 (13), pp.2418-2436. ⟨10.1128/MCB.00918-13⟩
Article dans une revue hal-00984591v1

Time-of-day-dependent variation of the human liver transcriptome and metabolome is disrupted in MASLD

Manuel Johanns , Joel Haas , Violetta Raverdy , Jimmy Vandel , Julie Chevalier-Dubois , et al.
JHEP Reports Innovation in Hepatology, 2024, 6 (1), pp.100948. ⟨10.1016/j.jhepr.2023.100948⟩
Article dans une revue hal-04528678v1
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Peroxisome proliferator-activated receptor γ regulates genes involved in insulin/insulin-like growth factor signaling and lipid metabolism during adipogenesis through functionally distinct enhancer classes.

Frederik Oger , Julie Dubois-Chevalier , Celine Gheeraert , Stephane Avner , Emmanuel Durand , et al.
Journal of Biological Chemistry, 2014, 289 (2), pp.708-22. ⟨10.1074/jbc.M113.526996⟩
Article dans une revue inserm-00912805v1
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Distinct but complementary contributions of PPAR isotypes to energy homeostasis

Vanessa Dubois , Jérôme Eeckhoute , Philippe Lefebvre , Bart Staels
Journal of Clinical Investigation, 2017, 127 (4), pp.1202 - 1214. ⟨10.1172/JCI88894⟩
Article dans une revue inserm-01709972v1

Time-of-day-dependent variation of the human liver transcriptome and metabolome is disrupted in MASLD

Manuel Johanns , Joel Haas , Violetta Raverdy , Jimmy Vandel , Julie Chevalier-Dubois , et al.
JHEP Reports Innovation in Hepatology, 2024, 6 (1), pp.100948. ⟨10.1016/j.jhepr.2023.100948⟩
Article dans une revue hal-04535291v1
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The nuclear bile acid receptor FXR is a PKA- and FOXA2-sensitive activator of fasting hepatic gluconeogenesis

Maheul Ploton , Claire Mazuy , Celine Gheeraert , Vanessa Dubois , Alexandre Berthier , et al.
Journal of Hepatology, 2018, 69 (5), pp.1099-1109. ⟨10.1016/j.jhep.2018.06.022⟩
Article dans une revue inserm-02108132v1
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Timed use of digoxin prevents heart ischemia-reperfusion injury through a REV-ERBα-UPS signaling pathway

Manjula Vinod , Alexandre Berthier , Xavier Maréchal , Céline Gheeraert , Raphaël Boutry , et al.
Nature Cardiovascular Research, 2022, pp.990-1005. ⟨10.1038/s44161-022-00148-z⟩
Article dans une revue inserm-03859910v1
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Loss of hepatocyte identity following aberrant YAP activation: a key mechanism in alcoholic hepatitis.

Mohamed Bou Saleh , Alexandre Louvet , Line Carolle Ntandja-Wandji , Emmanuel Boleslawski , Guillaume Lassailly , et al.
Journal of Hepatology, 2021, 75 (4), pp.912-923. ⟨10.1016/j.jhep.2021.05.041⟩
Article dans une revue hal-03279721v2

Maternal high-fat diet during suckling programs visceral adiposity and epigenetic regulation of adipose tissue stearoyl-CoA desaturase-1 in offspring

Laura Butruille , Lucie Marousez , Charlène Pourpe , Frédérik Oger , Simon Lecoutre , et al.
International Journal of Obesity, 2019, ⟨10.1038/s41366-018-0310-z⟩
Article dans une revue hal-02270933v1