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Call to arms: need for radiobiology in molecular radionuclide therapy

Samantha Terry , Julie Nonnekens , An Aerts , Sarah Baatout , Marion de Jong , et al.
European Journal of Nuclear Medicine and Molecular Imaging, 2019, 46 (8), pp.1588-1590. ⟨10.1007/s00259-019-04334-3⟩
Article dans une revue hal-02419386v1

Evaluation of two I-125-radiolabeled acridine derivatives for Auger-electron radionuclide therapy of melanoma

Maryline Gardette , Claire Viallard , Salomé Paillas , Jean-Luc Guerquin-Kern , Janine Papon , et al.
Investigational New Drugs, 2014, 32 (4), pp.587-597. ⟨10.1007/s10637-014-0086-5⟩
Article dans une revue hal-01456424v1
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RAPPORT DE PROSPECTIVE CSI INSB INSTITUT DES SCIENCES BIOLOGIQUES

Yaël Grosjean , Dominique Rumeau , Anne-Karine Bouzier-Sore , Marie Chabbert , Olivier Croce , et al.
CSI INSB INSTITUT DES SCIENCES BIOLOGIQUES. 2023
Rapport hal-04284459v1
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Introduction to Radiobiology of Targeted Radionuclide Therapy

Jean-Pierre Pouget , Catherine Lozza , Emmanuel Deshayes , Vincent Boudousq , Isabelle Navarro-Teulon
Frontiers in Medicine, 2015, 2, pp.12. ⟨10.3389/fmed.2015.00012⟩
Article dans une revue hal-01934653v1
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Apoptosis and p53 are not involved in the anti-tumor efficacy of (125)I-labeled monoclonal antibodies targeting the cell membrane.

Salomé Paillas , Laurent Boudou , Bérengère Piron , Nathalie Kersual , Manuel Bardiès , et al.
Nuclear Medicine and Biology, 2013, epub ahead of print. ⟨10.1016/j.nucmedbio.2013.02.001⟩
Article dans une revue inserm-00815724v1
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Drugs That Modify Cholesterol Metabolism Alter the p38/JNK-Mediated Targeted and Nontargeted Response to Alpha and Auger Radioimmunotherapy

Riad Ladjohounlou , Catherine Lozza , Alexandre Pichard , Julie Constanzo , Jihad Karam , et al.
Clinical Cancer Research, 2019, 25 (15), pp.4775-4790. ⟨10.1158/1078-0432.CCR-18-3295⟩
Article dans une revue hal-02279598v2
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Comparison of commercial dosimetric software platforms in patients treated with 177 Lu‐DOTATATE for peptide receptor radionuclide therapy

Erick Mora‐ramirez , Lore Santoro , Emmanuelle Cassol , Juan Ocampo‐ramos , Naomi Clayton , et al.
Medical Physics, 2020, 47 (9), pp.4602-4615. ⟨10.1002/mp.14375⟩
Article dans une revue hal-03344184v1
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Implementation of patient dosimetry in the clinical practice after targeted radiotherapy using [177Lu-[DOTA0, Tyr3]-octreotate

Lore Santoro , Erick Mora-Ramirez , Dorian Trauchessec , Soufiane Chouaf , Pierre Eustache , et al.
EJNMMI Research, 2018, 8, pp.103. ⟨10.1186/s13550-018-0459-4⟩
Article dans une revue hal-02292273v1
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Vaccination with human anti-trastuzumab anti-idiotype scFv reverses HER2 immunological tolerance and induces tumor immunity in MMTV.f.huHER2(Fo5) mice.

Maha Ladjemi , Thierry Chardes , Stephanie Corgnac , Veronique Garambois , Sebastien Morisseau , et al.
Breast Cancer Research, 2011, 13 (1), pp.R17. ⟨10.1186/bcr2826⟩
Article dans une revue inserm-00649414v1
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Antibody PEGylation in bioorthogonal pretargeting with trans-cyclooctene/tetrazine cycloaddition: in vitro and in vivo evaluation in colorectal cancer models

Aurélie Rondon , Nancy Ty , Jean-Baptiste Bequignat , Mercédès Quintana , Arnaud Briat , et al.
Scientific Reports, 2017, 7 (1), ⟨10.1038/s41598-017-15051-y⟩
Article dans une revue hal-01646770v1

Complex cell geometry and sources distribution model for Monte Carlo single cell dosimetry with iodine 125 radioimmunotherapy

François-Xavier Arnaud , S. Paillas , Jean-Pierre Pouget , S. Incerti , M. Bardiès , et al.
Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 2016, 366, pp.227-233. ⟨10.1016/j.nimb.2015.11.008⟩
Article dans une revue hal-02294314v1
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In myotonic dystrophy type 1 reduced FDG-uptake on FDG-PET is most severe in Brodmann area 8

Dimitri Renard , Laurent Collombier , Christel Castelli , Jean-Pierre Pouget , Pierre-Olivier Kotzki , et al.
BMC Neurology, 2016, 16, pp.100. ⟨10.1186/s12883-016-0630-3⟩
Article dans une revue hal-01903834v1
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Localized Irradiation of Cell Membrane by Auger Electrons Is Cytotoxic Through Oxidative Stress-Mediated Nontargeted Effects

Salomé Paillas , Riad Ladjohounlou , Catherine Lozza , Alexandre Pichard , Vincent Boudousq , et al.
Antioxidants and Redox Signaling, 2016, 25 (8), pp.467 - 484. ⟨10.1089/ars.2015.6309⟩
Article dans une revue hal-01905223v1
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Targeted Cancer Therapy with a Novel Anti-CD37 Beta-Particle Emitting Radioimmunoconjugate for Treatment of Non-Hodgkin Lymphoma

A.H.V. Repetto Llamazares , Roy H. Larsen , Sebastian Patzke , Karianne G. Fleten , David Didierlaurent , et al.
PLoS ONE, 2015, 10 (6), pp.e0128816. ⟨10.1371/journal.pone.0128816⟩
Article dans une revue hal-02275347v1
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Pretargeted radioimmunotherapy and SPECT imaging of peritoneal carcinomatosis using bioorthogonal click chemistry: probe selection and first proof-of-concept

Aurélie Rondon , Sébastien Schmitt , Arnaud Briat , Nancy Ty , Lydia Maigne , et al.
Theranostics, 2019, 9 (22), pp.6706-6718. ⟨10.7150/thno.35461⟩
Article dans une revue hal-02305887v1
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Tetraspanin 8 (TSPAN 8) as a potential target for radio-immunotherapy of colorectal cancer

Aurelie Maisonial-Besset , Tiffany Witkowski , Isabelle Navarro-Teulon , Odile Berthier-Vergnes , Giovanna Fois , et al.
Oncotarget, 2017, 8, pp.22034-22047. ⟨10.18632/oncotarget.15787⟩
Article dans une revue hal-01611133v1
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Rapid communication: insights into the role of extracellular vesicles during Auger radioimmunotherapy

Jihad Karam , Julie Constanzo , Alexandre Pichard , Laurent Gros , Joël Chopineau , et al.
International Journal of Radiation Biology, 2021, pp.1 - 10. ⟨10.1080/09553002.2021.1955999⟩
Article dans une revue hal-03367192v1
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Synthesis and in vitro antitumour activity of carboplatin analogues containing functional handles compatible for conjugation to drug delivery systems

Lisa-Maria Rečnik , Christophe Cantelli , Cyril Fersing , Céline Gongora , Jean-Pierre Pouget , et al.
Bioorganic and Medicinal Chemistry Letters, 2020, 30 (22), pp.127527. ⟨10.1016/j.bmcl.2020.127527⟩
Article dans une revue hal-03002939v1
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Noninternalizing monoclonal antibodies are suitable candidates for 125I radioimmunotherapy of small-volume peritoneal carcinomatosis.

Lore Santoro , Samir Boutaleb , Véronique Garambois , Caroline Bascoul-Mollevi , Vincent Boudousq , et al.
Journal of Nuclear Medicine, 2009, 50 (12), pp.2033-41. ⟨10.2967/jnumed.109.066993⟩
Article dans une revue inserm-00442929v1
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The human Mullerian inhibiting substance type II receptor as immunotherapy target for ovarian cancer. Validation using the mAb 12G4

Nathalie Kersual , Véronique Garambois , Thierry Chardès , Jean-Pierre Pouget , Imed Salhi , et al.
mAbs, 2014, 6, pp.1314--26. ⟨10.4161/mabs.29316⟩
Article dans une revue hal-02168055v1
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The Potential and Hurdles of Targeted Alpha Therapy - Clinical Trials and Beyond

Jorgen Elgqvist , S. Frost , Jean-Pierre Pouget , P. Albertsson
Frontiers in Oncology, 2014, 3, pp.324. ⟨10.3389/fonc.2013.00324⟩
Article dans une revue hal-02168053v1
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Brief intraperitoneal radioimmunotherapy of small peritoneal carcinomatosis using high activities of noninternalizing 125I-labeled monoclonal antibodies.

Vincent Boudousq , Stéphanie Ricaud , Véronique Garambois , Caroline Bascoul-Mollevi , Samir Boutaleb , et al.
Journal of Nuclear Medicine, 2010, 51 (11), pp.1748-55. ⟨10.2967/jnumed.110.080226⟩
Article dans une revue inserm-00531603v1

Modulation of DNA Damage by Pentoxifylline and ␣-Tocopherol in Skin Fibroblasts Exposed to Gamma Rays

Carine Laurent , Jean-Pierre Pouget , Philippe Voisin
Radiation Research, 2005, 163, pp.0 - 000. ⟨10.1667/RR3383⟩
Article dans une revue hal-02297374v1
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Cell Membrane is a More Sensitive Target than Cytoplasm to Dense Ionization Produced by Auger Electrons.

Jean-Pierre Pouget , Lore Santoro , Laure Raymond , Nicolas Chouin , Manuel Bardiès , et al.
Radiation Research, 2008, 170 (2), pp.192-200. ⟨10.1667/RR1359.1⟩
Article dans une revue inserm-00311037v1
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DNA damage-centered signaling pathways are effectively activated during low dose-rate Auger radioimmunotherapy.

Bérengère Piron , Salomé Paillas , Vincent Boudousq , André Pèlegrin , Caroline Bascoul-Mollevi , et al.
Nuclear Medicine and Biology, 2014, 41 Suppl, pp.e75-83. ⟨10.1016/j.nucmedbio.2014.01.012⟩
Article dans une revue inserm-00981411v1
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Radiolabeled Antibodies Against Müllerian-Inhibiting Substance Receptor, Type II: New Tools for a Theranostic Approach in Ovarian Cancer

Emmanuel Deshayes , Riad Ladjohounlou , Pierre Le Fur , Alexandre Pichard , Catherine Lozza , et al.
Journal of Nuclear Medicine, 2018, 59 (8), pp.1234 - 1242. ⟨10.2967/jnumed.118.208611⟩
Article dans une revue inserm-01885063v2
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The anti-tumor efficacy of 3C23K, a glyco-engineered humanized anti-MISRII antibody, in an ovarian cancer model is mainly mediated by engagement of immune effector cells

Pauline Estupina , Alexandre Fontayne , Jean-Marc Barret , Nathalie Kersual , Olivier Dubreuil , et al.
Oncotarget, 2017, 8 (23), pp.37061-37079. ⟨10.18632/oncotarget.15715⟩
Article dans une revue hal-02379710v1

Realistic multi-cellular dosimetry for 177 Lu-labelled antibodies: model and application

S. Marcatili , A. Pichard , A Courteau , R Ladjohounlou , I Navarro-Teulon , et al.
Physics in Medicine and Biology, 2016, 61 (19), pp.6935-6952. ⟨10.1088/0031-9155/61/19/6935⟩
Article dans une revue hal-02297934v1
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Peptides in Receptor-Mediated Radiotherapy: From Design to the Clinical Application in Cancers

Catherine Lozza , Isabelle Navarro-Teulon , André Pèlegrin , Jean-Pierre Pouget , Eric Vivès
Frontiers in Oncology, 2013, 3 (2), pp.332. ⟨10.3389/fonc.2013.00247⟩
Article dans une revue hal-03824440v1
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Artificial nutrition in patients with cancer has no impact on tumour glucose metabolism: Results of the PETANC Study

Emmanuel Deshayes , Hélène de Forges , Julien Fraisse , Marie-Claude Eberlé , Sophie Guillemard , et al.
Clinical Nutrition, 2018, ⟨10.1016/j.clnu.2018.08.033⟩
Article dans une revue hal-02285810v1