jean-philippe herbeuval

Documents

Identifiants chercheurs

jean-philippe-herbeuval
0000-0001-8114-8012
Google Scholar : https://scholar.google.com/citations?user=NB26Gi4AAAAJ&hl=fr
IdRef : 070408793

Présentation

Publications

	Spermine and spermidine bind CXCR4 and inhibit CXCR4- but not CCR5-tropic HIV-1 infection Mirja Harms , Nikaïa Smith , Mingyu Han , Rüdiger Groß , Pascal von Maltitz Science Advances , 2023, 9 (27), pp.eadf8251. ⟨10.1126/sciadv.adf8251⟩ Article dans une revue hal-04198762v1
	Targeting the chemokine receptor CXCR4 with histamine analog to reduce inflammation in juvenile arthritis Nassima Bekaddour , Nikaïa Smith , Benoit Beitz , Alba Llibre , Tom Dott Frontiers in Immunology, 2023, 14, pp.1178172. ⟨10.3389/fimmu.2023.1178172⟩ Article dans une revue pasteur-04245544v1
	Are blockers of gp120/CD4 interaction effective inhibitors of HIV-1 immunopathogenesis? Jean-Philippe Herbeuval , Gene Shearer Aids Reviews, 2023, 8 (1), pp.3-8 Article dans une revue hal-04198886v1
	Editorial: Type 1 interferon in pathologies, autoimmune diseases, and chronic viral infections: understanding the fascinating biologic role of type 1 interferons Jean-Philippe Herbeuval Frontiers in Immunology, 2023, 14, pp.1239086. ⟨10.3389/fimmu.2023.1239086⟩ Article dans une revue hal-04198755v1
	Pathogenic variants in the NLRP3 LRR domain at position 861 are responsible for a boost-dependent atypical CAPS phenotype. Antoine Fayand , Margaux Cescato , Laurent Le Corre , Alexandre Terré , Margaux Wacheux Journal of Allergy and Clinical Immunology, inPress, ⟨10.1016/j.jaci.2023.07.006⟩ Article dans une revue hal-04182567v1
	Successful treatment of JAK1 associated inflammatory disease Antoine Fayand , Véronique Hentgen , Céline Posseme , Carole Lacout , Capucine Picard Journal of Allergy and Clinical Immunology, 2023, 152 (4), pp.972-983. ⟨10.1016/j.jaci.2023.06.004⟩ Article dans une revue hal-04137977v1
	CXCR4 as a novel target in immunology: moving away from typical antagonists Birgit Caspar , Pietro Cocchiara , Armelle Melet , Kristof van Emelen , Annegret van der Aa Future Drug Discovery, 2022, 4 (2), pp.FDD77. ⟨10.4155/fdd-2022-0007⟩ Article dans une revue hal-04198790v1
	Correction to: Onset and Relapse of Juvenile Dermatomyositis Following Asymptomatic SARS-CoV-2 Infection Mathieu Paul Rodero , Stéphane Pelleau , Anne Welfringer-Morin , Darragh Duffy , Isabelle Melki Journal of Clinical Immunology, 2022, 42 (1), pp.28-28. ⟨10.1007/s10875-021-01135-y⟩ Article dans une revue hal-04198795v1
	Differential levels of IFNα subtypes in autoimmunity and viral infection Vincent Bondet , Mathieu P. Rodero , Céline Posseme , Pierre Bost , Jérémie Decalf Cytokine, 2021, pp.155533. ⟨10.1016/j.cyto.2021.155533⟩ Article dans une revue pasteur-03236276v1
	Differential levels of IFNα subtypes in autoimmunity and viral infection Jean-Philippe Herbeuval , Claude Lambert , Odile Sabido , Michèle Cottier , Pierre Fournel Cytokine, 2021, 144 (8), pp.155533. ⟨10.1093/jnci/95.8.611⟩ Article dans une revue hal-04198809v1
	JAK inhibitors are effective in a subset of patients with juvenile dermatomyositis: a monocentric retrospective study Tom Le Voyer , Cyril Gitiaux , François-Jérôme Authier , Christine Bodemer , Isabelle Melki Rheumatology, 2021, pp.keab116. ⟨10.1093/rheumatology/keab116⟩ Article dans une revue pasteur-03236464v1
	Beyond Anti-viral Effects of Chloroquine/Hydroxychloroquine Vincent Gies , Nassima Bekaddour , Yannick Dieudonné , Aurélien Guffroy , Quentin Frenger Frontiers in Immunology, 2020, 11, ⟨10.3389/FIMMU.2020.01409⟩ Article dans une revue hal-02996379v1
	Isolation of Tonsillar Mononuclear Cells to Study Ex Vivo Innate Immune Responses in a Human Mucosal Lymphoid Tissue Nikaïa Smith , Nassima Bekaddour , Nicolas Leboulanger , Yolande Richard , Jean-Philippe Herbeuval Journal of visualized experiments : JoVE, 2020, 160, ⟨10.3791/60914⟩ Article dans une revue hal-03051482v1
	Inhibition of IFNα secretion in cells from patients with juvenile dermatomyositis under TBK1 inhibitor treatment revealed by single-molecular assay technology Cyril Gitiaux , Vincent Bondet , Nassima Bekaddour , Patrick Nusbaum , Arnaud Hubas Rheumatology, 2020, pp.kez508. ⟨10.1093/rheumatology/kez508⟩ Article dans une revue pasteur-02376263v1
	Cerpegin-derived furo[3,4-c]pyridine-3,4(1H,5H)-diones enhance cellular response to interferons by de novo pyrimidine biosynthesis inhibition Simon Hayek , Nicolas Pietrancosta , Anna Hovhannisyan , Rodolphe Alves de Sousa , Nassima Bekaddour European Journal of Medicinal Chemistry, 2020, 186, pp.111855. ⟨10.1016/j.ejmech.2019.111855⟩ Article dans une revue hal-02372490v1
	Hitting the right spot on CXCR4 Jessica Mchugh , Jean-Philippe Herbeuval , Nikaia Smith Nature Reviews Rheumatology, 2019, 15 (9), pp.514-514. ⟨10.1038/s41584-019-0287-6⟩ Article dans une revue hal-02372533v1
	Control of TLR7-mediated type I IFN signaling in pDCs through CXCR4 engagement—A new target for lupus treatment Nikaïa Smith , Mathieu Rodéro , Nassima Bekaddour , Vincent Bondet , Yasser Ruiz-Blanco Science Advances , 2019, 5 (7), pp.eaav9019. ⟨10.1126/sciadv.aav9019⟩ Article dans une revue pasteur-02282952v1
	TRIM8 is required for virus-induced IFN response in human plasmacytoid dendritic cells Ghizlane Maarifi , Nikaïa Smith , Sarah Maillet , Olivier Moncorgé , Célia Chamontin Science Advances , 2019, 5 (11), pp.eaax3511. ⟨10.1126/sciadv.aax3511⟩ Article dans une revue hal-02404478v1
	Pollution chimique et immunité innée antivirale : des liaisons dangereuses ? Simon Hayek , Nicolas Pietrancosta , Rodolphe Alves De Sousa , Robert Barouki , Jean-Philippe Herbeuval Virologie, 2018, 22 (1), pp.27-40. ⟨10.1684/vir.2018.0718⟩ Article dans une revue hal-03652525v1
	Semen inhibits Zika virus infection of cells and tissues from the anogenital region Janis Müller , Mirja Harms , Franziska Krüger , Rüdiger Groß , Simone Joas Nature Communications, 2018, 9 (1), pp.2207. ⟨10.1038/s41467-018-04442-y⟩ Article dans une revue hal-04249967v1
	Identification of Primary Natural Killer Cell Modulators by Chemical Library Screening with a Luciferase-Based Functional Assay Simon Hayek , Nassima Bekaddour , Laurie Besson , Rodolphe Alves de Sousa , Nicolas Pietrancosta Slas Discovery, 2018, 24 (1), pp.25-37. ⟨10.1177/2472555218797078⟩ Article dans une revue hal-02324386v1
	Chemical pollution and innate antiviral immunity: Dangerous Liaisons ? Simon Hayek , Nicolas Pietrancosta , Rodolphe Alves De Sousa , Robert Barouki , Jean-Philippe Herbeuval Virologie, 2018, 22 (1), pp.1-13. ⟨10.1684/vir.2018.0717⟩ Article dans une revue hal-02351261v1
	Immature particles and capsid-free viral RNA produced by Yellow fever virus-infected cells stimulate plasmacytoid dendritic cells to secrete interferons Laura Sinigaglia , Ségolène Gracias , Elodie Décembre , Matthieu Fritz , Daniela Bruni Scientific Reports, 2018, 8 (1), ⟨10.1038/s41598-018-29235-7⟩ Article dans une revue hal-02327450v1
	Identification of a small molecule that primes the type I interferon response to cytosolic DNA Samira Khiar , Marianne Lucas-Hourani , Sebastien Nisole , Nikaia Smith , Olivier Helynck Scientific Reports, 2017, 7 (1), pp.2561. ⟨10.1038/s41598-017-02776-z⟩ Article dans une revue pasteur-01570224v1
	Microspectrofluorimetry to dissect the permeation of ceftazidime in Gram-negative bacteria Anas Allam , Laure Maigre , Julia Vergalli , Estelle Dumont , Bertrand Cinquin Scientific Reports, 2017, 7 (1), pp.986. ⟨10.1038/s41598-017-00945-8⟩ Article dans une revue hal-01831783v1
	CXCR4, le nouveau régulateur de l’immunité innée ? Nikaïa Smith , Nicolas Pietrancosta , Jean-Philippe Herbeuval Médecine/Sciences, 2017, 33 (8-9), pp.711-713. ⟨10.1051/medsci/20173308008⟩ Article dans une revue hal-02351272v1
	Microspectrofluorimetry to dissect the permeation of ceftazidime in Gram-negative bacteria Anas Allam , Laure Maigre , Julia Vergalli , Estelle Dumont , Bertrand Cinquin Scientific Reports, 2017, 7 (1), pp.986. ⟨10.1038/s41598-017-00945-8⟩ Article dans une revue hal-03652530v1
	Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement Nikaïa Smith , Nicolas Pietrancosta , Sophia Davidson , Jacques Dutrieux , Lise Chauveau Nature Communications, 2017, 8, pp.14253. ⟨10.1038/ncomms14253⟩ Article dans une revue hal-02075366v1
	An efficient method for gene silencing in human primary plasmacytoid dendritic cells: silencing of the TLR7/IRF-7 pathway as a proof of concept Nikaïa Smith , Pierre-Olivier Vidalain , Sébastien Nisole , Jean-Philippe Herbeuval Scientific Reports, 2016, 6 (1), ⟨10.1038/srep29891⟩ Article dans une revue hal-02438269v1
	Plasmacytoid dendritic cells and myeloid cells differently contribute to BAFF over-expression during primary HIV infection Gwenoline Borhis , Chantal Burelout , Nada Chaoul , Nikaïa Smith , Cecile Goujard AIDS. Official journal of the international AIDS Society, 2016, pp.1. ⟨10.1097/QAD.0000000000000965⟩ Article dans une revue hal-02346130v1
	Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-α Production in Women. Morgane Griesbeck , Susanne Ziegler , Sophie Laffont , Nikaïa Smith , Lise Chauveau Journal of Immunology, 2015, 195 (11), pp.5327-36. ⟨10.4049/jimmunol.1501684⟩ Article dans une revue pasteur-01372393v1
	Reduction of death receptor 5 expression and apoptosis of CD4+ T cells from HIV controllers Lucie Barblu , Nikaïa Smith , Stéphanie Durand , Daniel Scott-Algara , Faroudy Boufassa Clinical Immunology, 2014, 155 (1), pp.17-26. ⟨10.1016/j.clim.2014.07.010⟩ Article dans une revue hal-02322630v1
	RasV12 induces Survivin/AuroraB pathway conferring tumor cell apoptosis resistance Réda Hadj-Slimane , Perayot Pamonsinlapatham , Jean-Philippe Herbeuval , Christiane Garbay , Yves Lepelletier Cellular Signalling, 2010, 22 (8), pp.1214-1221. ⟨10.1016/j.cellsig.2010.03.013⟩ Article dans une revue hal-04250005v1
	Free HTLV-1 induces TLR7-dependent innate immune response and TRAIL relocalization in killer plasmacytoid dendritic cells Renaud Colisson , Lucie Barblu , Christophe Gras , Françoise Raynaud , Reda Hadj-Slimane Blood, 2010, 115 (11), pp.2177-2185. ⟨10.1182/blood-2009-06-224741⟩ Article dans une revue hal-04249994v1
	Rasv12 induces survivin/auroraB pathway conferring tumor cell apoptosis resistance Réda Hadj-Slimane , Perayot Pamonsinlapatham , Jean-Philippe Herbeuval , Christiane Garbay , Yves Lepelletier Cellular Signalling, 2010, 22 (8), pp.1214-1221. ⟨10.1016/j.cellsig.2010.03.013⟩ Article dans une revue hal-00473108v1
	HAART reduces death ligand but not death receptors in lymphoid tissue of HIV-infected patients and simian immunodeficiency virus-infected macaques Jean-Philippe Herbeuval , Jakob Nilsson , Adriano Boasso , Andrew Hardy , Monica Vaccari AIDS. Official journal of the international AIDS Society, 2009, 23 (1), pp.35-40. ⟨10.1097/QAD.0b013e32831cb907⟩ Article dans une revue hal-04204741v1
	HIV-1 immunopathogenesis: How good interferon turns bad Jean-Philippe Herbeuval , Gene Shearer Clinical Immunology, 2007, 123 (2), pp.121-128. ⟨10.1016/j.clim.2006.09.016⟩ Article dans une revue hal-04204725v1
	HIV turns plasmacytoid dendritic cells (pDC) into TRAIL-expressing killer pDC and down-regulates HIV coreceptors by Toll-like receptor 7-induced IFN-α Andrew Hardy , David Graham , Gene Shearer , Jean-Philippe Herbeuval Proceedings of the National Academy of Sciences of the United States of America, 2007, 104 (44), pp.17453-17458. ⟨10.1073/pnas.0707244104⟩ Article dans une revue hal-04204737v1
	Differential expression of IFN-α and TRAIL/DR5 in lymphoid tissue of progressor versus nonprogressor HIV-1-infected patients Jean-Philippe Herbeuval , Jakob Nilsson , Adriano Boasso , Andrew Hardy , Michael Kruhlak Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (18), pp.7000-7005. ⟨10.1073/pnas.0600363103⟩ Article dans une revue hal-04198879v1
	HIV inhibits CD4+ T-cell proliferation by inducing indoleamine 2,3-dioxygenase in plasmacytoid dendritic cells Adriano Boasso , Jean-Philippe Herbeuval , Andrew Hardy , Stephanie Anderson , Matthew Dolan Blood, 2006, 109 (8), pp.3351-3359. ⟨10.1182/blood-2006-07-034785⟩ Article dans une revue hal-04204732v1
	Regulation of indoleamine 2,3-dioxygenase and tryptophanyl-tRNA-synthetase by CTLA-4-Fc in human CD4+ T cells Adriano Boasso , Jean-Philippe Herbeuval , Andrew Hardy , Christiana Winkler , Gene Shearer Blood, 2005, 105 (4), pp.1574-1581. ⟨10.1182/blood-2004-06-2089⟩ Article dans une revue hal-04198822v1
	TNF-related apoptosis-inducing ligand (TRAIL) in HIV-1-infected patients and its in vitro production by antigen-presenting cells Jean-Philippe Herbeuval , Adriano Boasso , Jean-Charles Grivel , Andrew Hardy , Stephanie Anderson Blood, 2005, 105 (6), pp.2458-2464. ⟨10.1182/blood-2004-08-3058⟩ Article dans une revue hal-04198864v1
	CD4+ T-cell death induced by infectious and noninfectious HIV-1: role of type 1 interferon-dependent, TRAIL/DR5-mediated apoptosis Jean-Philippe Herbeuval , Jean-Charles Grivel , Adriano Boasso , Andrew Hardy , Claire Chougnet Blood, 2005, 106 (10), pp.3524-3531. ⟨10.1182/blood-2005-03-1243⟩ Article dans une revue hal-04198872v1
	Regulation of TNF-related apoptosis-inducing ligand on primary CD4 + T cells by HIV-1: Role of type I IFN-producing plasmacytoid dendritic cells Jean-Philippe Herbeuval , Andrew Hardy , Adriano Boasso , Stephanie Anderson , Matthew Dolan Proceedings of the National Academy of Sciences of the United States of America, 2005, 102 (39), pp.13974-13979. ⟨10.1073/pnas.0505251102⟩ Article dans une revue hal-04198875v1
	Recruitment of STAT3 for Production of IL-10 by Colon Carcinoma Cells Induced by Macrophage-Derived IL-6 Eric Lelievre , Claude Lambert , Michel Dy , Christian Genin , Jean-Philippe Herbeuval Journal of Immunology, 2004, 172 (7), pp.4630-4636. ⟨10.4049/jimmunol.172.7.4630⟩ Article dans une revue hal-04249987v1
	Macrophages From Cancer Patients: Analysis of TRAIL, TRAIL Receptors, and Colon Tumor Cell Apoptosis Jean-Philippe Herbeuval , Claude Lambert , Odile Sabido , Michèle Cottier , Pierre Fournel JNCI: Journal of the National Cancer Institute, 2003, 95 (8), pp.611-621. ⟨10.1093/jnci/95.8.611⟩ Article dans une revue hal-04198816v1

	In Vitro Functionally Selective Immunomodulator Shows Robust Efficacy in Pristane-induced Murine Lupus Model Jean Philippe Herbeuval 19th World Congress of Basic and Clinical Pharmacology (WCP), Jul 2023, Glasgow, United Kingdom. pp.561-561 Communication dans un congrès hal-04255619v1
	Screening the signalling behaviour of immunomodulating compounds at CXCR4 Jean Philippe Herbeuval 19th World Congress of Basic and Clinical Pharmacology (WCP), Jul 2023, Glasgow, France. pp.670-671 Communication dans un congrès hal-04255631v1

	Targeting the chemokine receptor CXCR4 with histamine analogue to reduce inflammation in juvenile arthritis: a proof of concept for COVID-19 therapeutic approach Nassima Bekaddour , Nikaïa Smith , Benoit Beitz , Alba Llibre , Tom Dott 2021 Pré-publication, Document de travail hal-03430524v1

jean-philippe herbeuval

Présentation

Publications

Spermine and spermidine bind CXCR4 and inhibit CXCR4- but not CCR5-tropic HIV-1 infection

Targeting the chemokine receptor CXCR4 with histamine analog to reduce inflammation in juvenile arthritis

Are blockers of gp120/CD4 interaction effective inhibitors of HIV-1 immunopathogenesis?

Editorial: Type 1 interferon in pathologies, autoimmune diseases, and chronic viral infections: understanding the fascinating biologic role of type 1 interferons

Pathogenic variants in the NLRP3 LRR domain at position 861 are responsible for a boost-dependent atypical CAPS phenotype.

Successful treatment of JAK1 associated inflammatory disease

CXCR4 as a novel target in immunology: moving away from typical antagonists

Correction to: Onset and Relapse of Juvenile Dermatomyositis Following Asymptomatic SARS-CoV-2 Infection

Differential levels of IFNα subtypes in autoimmunity and viral infection

Differential levels of IFNα subtypes in autoimmunity and viral infection

JAK inhibitors are effective in a subset of patients with juvenile dermatomyositis: a monocentric retrospective study

Beyond Anti-viral Effects of Chloroquine/Hydroxychloroquine

Isolation of Tonsillar Mononuclear Cells to Study Ex Vivo Innate Immune Responses in a Human Mucosal Lymphoid Tissue

Inhibition of IFNα secretion in cells from patients with juvenile dermatomyositis under TBK1 inhibitor treatment revealed by single-molecular assay technology

Cerpegin-derived furo[3,4-c]pyridine-3,4(1H,5H)-diones enhance cellular response to interferons by de novo pyrimidine biosynthesis inhibition

Hitting the right spot on CXCR4

Control of TLR7-mediated type I IFN signaling in pDCs through CXCR4 engagement—A new target for lupus treatment

TRIM8 is required for virus-induced IFN response in human plasmacytoid dendritic cells

Pollution chimique et immunité innée antivirale : des liaisons dangereuses ?

Semen inhibits Zika virus infection of cells and tissues from the anogenital region

Identification of Primary Natural Killer Cell Modulators by Chemical Library Screening with a Luciferase-Based Functional Assay

Chemical pollution and innate antiviral immunity: Dangerous Liaisons ?

Immature particles and capsid-free viral RNA produced by Yellow fever virus-infected cells stimulate plasmacytoid dendritic cells to secrete interferons

Identification of a small molecule that primes the type I interferon response to cytosolic DNA

Microspectrofluorimetry to dissect the permeation of ceftazidime in Gram-negative bacteria

CXCR4, le nouveau régulateur de l’immunité innée ?

Microspectrofluorimetry to dissect the permeation of ceftazidime in Gram-negative bacteria

Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement

An efficient method for gene silencing in human primary plasmacytoid dendritic cells: silencing of the TLR7/IRF-7 pathway as a proof of concept

Plasmacytoid dendritic cells and myeloid cells differently contribute to BAFF over-expression during primary HIV infection

Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-α Production in Women.

Reduction of death receptor 5 expression and apoptosis of CD4+ T cells from HIV controllers

RasV12 induces Survivin/AuroraB pathway conferring tumor cell apoptosis resistance

Free HTLV-1 induces TLR7-dependent innate immune response and TRAIL relocalization in killer plasmacytoid dendritic cells

Rasv12 induces survivin/auroraB pathway conferring tumor cell apoptosis resistance

HAART reduces death ligand but not death receptors in lymphoid tissue of HIV-infected patients and simian immunodeficiency virus-infected macaques

HIV-1 immunopathogenesis: How good interferon turns bad

HIV turns plasmacytoid dendritic cells (pDC) into TRAIL-expressing killer pDC and down-regulates HIV coreceptors by Toll-like receptor 7-induced IFN-α

Differential expression of IFN-α and TRAIL/DR5 in lymphoid tissue of progressor versus nonprogressor HIV-1-infected patients

HIV inhibits CD4+ T-cell proliferation by inducing indoleamine 2,3-dioxygenase in plasmacytoid dendritic cells

Regulation of indoleamine 2,3-dioxygenase and tryptophanyl-tRNA-synthetase by CTLA-4-Fc in human CD4+ T cells

TNF-related apoptosis-inducing ligand (TRAIL) in HIV-1-infected patients and its in vitro production by antigen-presenting cells

CD4+ T-cell death induced by infectious and noninfectious HIV-1: role of type 1 interferon-dependent, TRAIL/DR5-mediated apoptosis

Regulation of TNF-related apoptosis-inducing ligand on primary CD4 + T cells by HIV-1: Role of type I IFN-producing plasmacytoid dendritic cells

Recruitment of STAT3 for Production of IL-10 by Colon Carcinoma Cells Induced by Macrophage-Derived IL-6

Macrophages From Cancer Patients: Analysis of TRAIL, TRAIL Receptors, and Colon Tumor Cell Apoptosis

In Vitro Functionally Selective Immunomodulator Shows Robust Efficacy in Pristane-induced Murine Lupus Model

Screening the signalling behaviour of immunomodulating compounds at CXCR4

Targeting the chemokine receptor CXCR4 with histamine analogue to reduce inflammation in juvenile arthritis: a proof of concept for COVID-19 therapeutic approach

CXCR4, le nouveau régulateur de l’immunité innée ?