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Number of documents

18

Expériences professionnelles/diplômes


 

2021     Nomination Commission Nationale 1-Fondation ARC: Immunologie-Onco-hématologie-Microbiologie

 

2020     Membre du Jury "année de recherche" pour les internes en médecine, Faculté de Médecine Paris-Saclay

 

2019     Promotion au grade DR1 commission 27 CNRS

 

2019     Fondateur Scientifique ERMIUM Therapeutics, Société par action simplifiées (SAS)

 

2019     Président du comité scientifique d’ERMIUM Therapeutics

 

2019     Expert scientifique, Deeptech Founders, BPI

 

2018     Formation à la création d’entreprise DeepTech Founders, Ministère de la Recherche, BPI France

 

2018     Direction de la plateforme de biologie moléculaire de la Faculté Biomédicale des Saints-Pères, Paris

 

2016     Direction de la plateforme cytométrie de flux Faculté Biomédicale des Saints-Pères Paris, Paris

 

2015     Création de la Fondation SantImmune hébergée par la Fondation Paris Descartes

 

2013     Membre du conseil scientifique du CICB, Paris

 

2013     Promotion au grade DR2, commission 27 CNRS

 

2012     Création de l’équipe CBMIT, CNRS UMR 8601, Université Paris Descartes

 

2008     Habilitation à Diriger des Recherches (HDR), Université Paris Descartes.

 

2006     Recrutement CR1, commission 24, CNRS UMR 8147, Hôpital Necker, Paris

 

2001     Postdoctorat, Fogarty fellowship, laboratoire du Dr. Gene Shearer EIB, NCI, NIH, Bethesda, USA,

 

2001     Doctorat d’Immunologie, GIMAP-INSERM Université Jean Monnet

 

1999     Monitorat à la Faculté des Sciences, Université Jean Monnet

 


Journal articles18 documents

  • Vincent Gies, Nassima Bekaddour, Yannick Dieudonné, Aurélien Guffroy, Quentin Frenger, et al.. Beyond Anti-viral Effects of Chloroquine/Hydroxychloroquine. Frontiers in Immunology, Frontiers, 2020, 11, ⟨10.3389/FIMMU.2020.01409⟩. ⟨hal-02996379⟩
  • Cyril Gitiaux, Vincent Bondet, Nassima Bekaddour, Patrick Nusbaum, Arnaud Hubas, et al.. Inhibition of IFNα secretion in cells from patients with juvenile dermatomyositis under TBK1 inhibitor treatment revealed by single-molecular assay technology. Rheumatology, Oxford University Press (OUP), 2020, pp.kez508. ⟨10.1093/rheumatology/kez508⟩. ⟨pasteur-02376263⟩
  • Simon Hayek, Nicolas Pietrancosta, Anna Hovhannisyan, Rodolphe Alves de Sousa, Nassima Bekaddour, et al.. Cerpegin-derived furo[3,4-c]pyridine-3,4(1H,5H)-diones enhance cellular response to interferons by de novo pyrimidine biosynthesis inhibition. European Journal of Medicinal Chemistry, Elsevier, 2020, 186, pp.111855. ⟨10.1016/j.ejmech.2019.111855⟩. ⟨hal-02372490⟩
  • Ghizlane Maarifi, Nikaïa Smith, Sarah Maillet, Olivier Moncorgé, Célia Chamontin, et al.. TRIM8 is required for virus-induced IFN response in human plasmacytoid dendritic cells. Science Advances , American Association for the Advancement of Science (AAAS), 2019, 5 (11), pp.eaax3511. ⟨10.1126/sciadv.aax3511⟩. ⟨hal-02404478⟩
  • Jessica Mchugh, Jean-Philippe Herbeuval, Nikaia Smith. Hitting the right spot on CXCR4. Nature Reviews Rheumatology, Nature Publishing Group, 2019, 15 (9), pp.514-514. ⟨10.1038/s41584-019-0287-6⟩. ⟨hal-02372533⟩
  • Nikaïa Smith, Mathieu Rodéro, Nassima Bekaddour, Vincent Bondet, Yasser Ruiz-Blanco, et al.. Control of TLR7-mediated type I IFN signaling in pDCs through CXCR4 engagement—A new target for lupus treatment. Science Advances , American Association for the Advancement of Science (AAAS), 2019, 5 (7), pp.eaav9019. ⟨10.1126/sciadv.aav9019⟩. ⟨pasteur-02282952⟩
  • Simon Hayek, Nassima Bekaddour, Laurie Besson, Rodolphe Alves de Sousa, Nicolas Pietrancosta, et al.. Identification of Primary Natural Killer Cell Modulators by Chemical Library Screening with a Luciferase-Based Functional Assay. Slas Discovery, SAGE Publishing, 2018, 24 (1), pp.25-37. ⟨10.1177/2472555218797078⟩. ⟨hal-02324386⟩
  • Simon Hayek, Nicolas Pietrancosta, Rodolphe Alves De Sousa, Robert Barouki, Jean-Philippe Herbeuval, et al.. Chemical pollution and innate antiviral immunity: Dangerous Liaisons ?. Virologie, John Libbey Eurotext 2018, 22 (1), pp.1-13. ⟨10.1684/vir.2018.0717⟩. ⟨hal-02351261⟩
  • Laura Sinigaglia, Ségolène Gracias, Elodie Décembre, Matthieu Fritz, Daniela Bruni, et al.. Immature particles and capsid-free viral RNA produced by Yellow fever virus-infected cells stimulate plasmacytoid dendritic cells to secrete interferons. Scientific Reports, Nature Publishing Group, 2018, 8 (1), ⟨10.1038/s41598-018-29235-7⟩. ⟨hal-02327450⟩
  • Nikaïa Smith, Nicolas Pietrancosta, Jean-Philippe Herbeuval. CXCR4, le nouveau régulateur de l’immunité innée ?. médecine/sciences, EDP Sciences, 2017, 33 (8-9), pp.711-713. ⟨10.1051/medsci/20173308008⟩. ⟨hal-02351272⟩
  • Anas Allam, Laure Maigre, Julia Vergalli, Estelle Dumont, Bertrand Cinquin, et al.. Microspectrofluorimetry to dissect the permeation of ceftazidime in Gram-negative bacteria. Scientific Reports, Nature Publishing Group, 2017, 7 (1), pp.986. ⟨10.1038/s41598-017-00945-8⟩. ⟨hal-01831783⟩
  • Samira Khiar, Marianne Lucas-Hourani, Sebastien Nisole, Nikaia Smith, Olivier Helynck, et al.. Identification of a small molecule that primes the type I interferon response to cytosolic DNA. Scientific Reports, Nature Publishing Group, 2017, 7 (1), pp.2561. ⟨10.1038/s41598-017-02776-z⟩. ⟨pasteur-01570224⟩
  • Nikaïa Smith, Nicolas Pietrancosta, Sophia Davidson, Jacques Dutrieux, Lise Chauveau, et al.. Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement. Nature Communications, Nature Publishing Group, 2017, 8, pp.14253. ⟨10.1038/ncomms14253⟩. ⟨hal-02075366⟩
  • Gwenoline Borhis, Chantal Burelout, Nada Chaoul, Nikaïa Smith, Cecile Goujard, et al.. Plasmacytoid dendritic cells and myeloid cells differently contribute to BAFF over-expression during primary HIV infection. AIDS, Lippincott, Williams & Wilkins, 2016, pp.1. ⟨10.1097/QAD.0000000000000965⟩. ⟨hal-02346130⟩
  • Nikaïa Smith, Pierre-Olivier Vidalain, Sébastien Nisole, Jean-Philippe Herbeuval. An efficient method for gene silencing in human primary plasmacytoid dendritic cells: silencing of the TLR7/IRF-7 pathway as a proof of concept. Scientific Reports, Nature Publishing Group, 2016, 6 (1), ⟨10.1038/srep29891⟩. ⟨hal-02438269⟩
  • Morgane Griesbeck, Susanne Ziegler, Sophie Laffont, Nikaïa Smith, Lise Chauveau, et al.. Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-α Production in Women.. Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2015, 195 (11), pp.5327-36. ⟨10.4049/jimmunol.1501684⟩. ⟨pasteur-01372393⟩
  • Lucie Barblu, Nikaïa Smith, Stéphanie Durand, Daniel Scott-Algara, Faroudy Boufassa, et al.. Reduction of death receptor 5 expression and apoptosis of CD4+ T cells from HIV controllers. Clinical Immunology, Elsevier, 2014, 155 (1), pp.17-26. ⟨10.1016/j.clim.2014.07.010⟩. ⟨hal-02322630⟩
  • Réda Hadj-Slimane, Perayot Pamonsinlapatham, Jean-Philippe Herbeuval, Christiane Garbay, Yves Lepelletier, et al.. Rasv12 induces survivin/auroraB pathway conferring tumor cell apoptosis resistance. Cellular Signalling, Elsevier, 2010, 22 (8), pp.1214-1221. ⟨10.1016/j.cellsig.2010.03.013⟩. ⟨hal-00473108⟩