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Defining the impact on yeast ATP synthase of two pathogenic human mitochondrial DNA mutations, T9185C and T9191C.

Anna Magdalena Kabala , Jean-Paul Lasserre , Sharon H Ackerman , Jean-Paul Di Rago , Roza Kucharczyk
Biochimie, 2014, epub ahead of print. ⟨10.1016/j.biochi.2013.11.024⟩
Article dans une revue hal-00940330v1

Flavonoids as Potential Drugs for VPS13-Dependent Rare Neurodegenerative Diseases

Jean-Paul Di Rago
Genes, 2020, 11 (7), pp.828. ⟨10.3390/genes11070828⟩
Article dans une revue hal-03103175v1
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Regulation of Aerobic Energy Metabolism in Podospora anserina by Two Paralogous Genes Encoding Structurally Different c-Subunits of ATP Synthase

Carole H. Sellem , Jean-Paul Di Rago , Jean-Paul Lasserre , Sharon H. Ackerman , Annie Sainsard-Chanet
PLoS Genetics, 2016, 12 (7), ⟨10.1371/journal.pgen.1006161⟩
Article dans une revue hal-01412332v1
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The Unique Cysteine of F-ATP Synthase OSCP Subunit Participates in Modulation of the Permeability Transition Pore

Michela Carraro , Kristen Jones , Geppo Sartori , Marco Schiavone , Salvatore Antonucci , et al.
Cell Reports, 2020, 32 (9), pp.108095. ⟨10.1016/j.celrep.2020.108095⟩
Article dans une revue hal-03103150v1

The depletion of F1 subunit {varepsilon} in yeast leads to an uncoupled respiratory phenotype that is rescued by mutations in the proton translocating subunits of F0.

Emmanuel Tetaud , François Godard , Marie-France Giraud , Sharon H Ackerman , Jean-Paul Di Rago
Molecular Biology of the Cell, 2014, 25 (6), pp.791-99. ⟨10.1091/mbc.E13-02-0112⟩
Article dans une revue hal-00940281v1

TMEM70 forms oligomeric scaffolds within mitochondrial cristae promoting in situ assembly of mammalian ATP synthase proton channel

Hela Bahri , Jeremie Buratto , Manuel Rojo , Jim Paul Dompierre , Bénédicte Salin , et al.
Biochimica et Biophysica Acta - Molecular Cell Research, 2020, pp.118942. ⟨10.1016/j.bbamcr.2020.118942⟩
Article dans une revue hal-03103088v1
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ATP Synthase Diseases of Mitochondrial Genetic Origin

Alain Dautant , Thomas Meier , Alexander Hahn , Deborah Tribouillard-Tanvier , Jean-Paul Di Rago , et al.
Frontiers in Physiology, 2018, 9, ⟨10.3389/fphys.2018.00329⟩
Article dans une revue hal-02398397v1
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Case Report: Identification of a Novel Variant (m.8909T>C) of Human Mitochondrial ATP6 Gene and Its Functional Consequences on Yeast ATP Synthase

Qiuju Ding , Róża Kucharczyk , Weiwei Zhao , Alain Dautant , Shutian Xu , et al.
Article dans une revue hal-02988793v1
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TMEM70 forms oligomeric scaffolds within mitochondrial cristae promoting in situ assembly of mammalian ATP synthase proton channel

Hela Bahri , Jérémie Buratto , Manuel Rojo , Jim Dompierre , Bénédicte Salin , et al.
2020
Pré-publication, Document de travail hal-03034356v1

Experimental Relocation of the Mitochondrial ATP9 Gene to the Nucleus Reveals Forces Underlying Mitochondrial Genome Evolution.

Maïlis Bietenhader , Alexandre Martos , Emmanuel Tetaud , Raeka S Aiyar , Carole H Sellem , et al.
PLoS Genetics, 2012, 8 (8), pp.e1002876. ⟨10.1371/journal.pgen.1002876⟩
Article dans une revue hal-00735337v1

The energetic state of mitochondria modulates complex III biogenesis through the ATP-dependent activity of Bcs1.

Jelena Ostojić , Cristina Panozzo , Jean-Paul Lasserre , Cécile Nouet , Florence Courtin , et al.
Cell Metab, 2013, 18 (4), pp.567-77. ⟨10.1016/j.cmet.2013.08.017⟩
Article dans une revue hal-00905852v1
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The pathogenic MT-ATP6 m.8851T>C mutation prevents proton movements within the n-side hydrophilic cleft of the membrane domain of ATP synthase

Alain Dautant , Roza Kucharczyk , Kewin Gombeau , François Godard , Déborah Tribouillard-Tanvier , et al.
Biochimica biophysica acta (BBA) - Bioenergetics, 2019, 1860 (7), pp.562-572. ⟨10.1016/j.bbabio.2019.06.002⟩
Article dans une revue hal-02988559v1
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Assigning mitochondrial localization of dual localized proteins using a yeast Bi-Genomic Mitochondrial-Split-GFP

Gaétan Bader , Ludovic Enkler , Yuhei Araiso , Marine Hemmerle , Krystyna Binko , et al.
Article dans une revue hal-02898815v1

Two nuclear life-cycle-regulated genes encode interchangeable subunits c of mitochondrial ATP synthase in Podospora anserina.

Michelle Déquard-Chablat , Carole H Sellem , Pawel Golik , Frédérique Bidard , Alexandre Martos , et al.
Molecular Biology and Evolution, 2011, epub ahead of print. ⟨10.1093/molbev/msr025⟩
Article dans une revue hal-00574233v1

Functional investigation of an universally conserved leucine residue in subunit a of ATP synthase targeted by the pathogenic m.9176 T>G mutation

Roza Kucharczyk , Alain Dautant , François Godard , Deborah Tribouillard-Tanvier , Jean-Paul Di Rago
Biochimica biophysica acta (BBA) - Bioenergetics, 2019, 1860 (1), pp.52-59. ⟨10.1016/j.bbabio.2018.11.005⟩
Article dans une revue hal-02404981v1
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Molecular Basis of the Pathogenic Mechanism Induced by the m.9191T>C Mutation in Mitochondrial ATP6 Gene

Alain Dautant , Xin Su , François Godard , Marine Bouhier , Teresa Zoladek , et al.
International Journal of Molecular Sciences, 2020, 21, ⟨10.3390/ijms21145083⟩
Article dans une revue hal-02988568v1
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Decreasing cytosolic translation is beneficial to yeast and human tafazzin-deficient cells

Maxence de Taffin de Tilques , Jean-Paul Lasserre , François Godard , Elodie Sardin , Marine Bouhier , et al.
Microbial Cell , 2018, 5 (5), pp.1-13. ⟨10.15698/mic2018.05.629⟩
Article dans une revue hal-02628099v1

Molecular basis of diseases caused by the mtDNA mutation m.8969G>A in the subunit a of ATP synthase

Natalia Skoczen , Alain Dautant , Krystyna Binko , François Godard , Marine Bouhier , et al.
Biochimica biophysica acta (BBA) - Bioenergetics, 2018, 1859 (8), pp.602-611. ⟨10.1016/j.bbabio.2018.05.009⟩
Article dans une revue hal-02398396v1
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Overexpression of mitochondrial oxodicarboxylate carrier (ODC1) preserves oxidative phosphorylation in a yeast model of Barth syndrome

Maxence de Taffin de Tilques , Deborah Tribouillard-Tanvier , Emmanuel Tetaud , Eric Testet , Jean-Paul Di Rago , et al.
Disease Models & Mechanisms, 2017, 10 (4), pp.439-450. ⟨10.1242/dmm.027540⟩
Article dans une revue hal-01600647v1

A "petite obligate" mutant of Saccharomyces cerevisiae: functional mtDNA is lethal in cells lacking the delta subunit of mitochondrial F1-ATPase.

Stéphane Duvezin-Caubet , Malgorzata Rak , Linnka Lefebvre-Legendre , Emmanuel Tetaud , Nathalie Bonnefoy , et al.
Journal of Biological Chemistry, 2006, 281 (24), pp.16305-13. ⟨10.1074/jbc.M513805200⟩
Article dans une revue hal-00132178v1

Yeast as a system for modeling mitochondrial disease mechanisms and discovering therapies.

Jean-Paul Lasserre , Alain Dautant , Raeka S Aiyar , Roza Kucharczyk , Annie Glatigny , et al.
Disease Models & Mechanisms, 2015, 8 (6), pp.509-26. ⟨10.1242/dmm.020438⟩
Article dans une revue hal-01199669v1

Deregulating mitochondrial metabolite and ion transport has beneficial effects in yeast and human cellular models for NARP syndrome

Xin Su , Malgorzata Rak , Emmanuel Tetaud , François Godard , Elodie Sardin , et al.
Human Molecular Genetics, 2019, 28 (22), pp.3792-3804. ⟨10.1093/hmg/ddz160⟩
Article dans une revue hal-02362008v1

Mitochondrial DNA mutations provoke dominant inhibition of mitochondrial inner membrane fusion.

Cécile Sauvanet , Stéphane Duvezin-Caubet , Bénédicte Salin , Claudine David , Aurélie Massoni-Laporte , et al.
PLoS ONE, 2012, 7 (11), pp.e49639. ⟨10.1371/journal.pone.0049639⟩
Article dans une revue hal-00757387v1

Defining the pathogenesis of human mtDNA mutations using a yeast model: The case of T8851C.

Roza Kucharczyk , Marie-France Giraud , Daniel Brèthes , Monica Wysocka-Kapcinska , Nahia Ezkurdia , et al.
International Journal of Biochemistry and Cell Biology, 2013, 45 (1), pp.130-40. ⟨10.1016/j.biocel.2012.07.001⟩
Article dans une revue istex hal-00735756v1