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Development and characterization of a human three-dimensional chondrosarcoma culture for in vitro drug testing

 Aurélien Voissiere , Elodie Jouberton , Elise Maubert , Françoise Degoul , Caroline Peyrode , et al.
PLoS ONE, 2017, 12 (7), pp.e0181340. ⟨10.1371/journal.pone.0181340⟩
Article dans une revue hal-01647014v1
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In vitro cytotoxic effects of DEHP-alternative plasticizers and their primary metabolites on a L929 cell line

 Teuta Eljezi , Pierre Pinta , Damien Richard Richard , Jérémy Pinguet , Jean-Michel Chezal , et al.
Chemosphere, 2017, 173, pp.452 - 459. ⟨10.1016/j.chemosphere.2017.01.026⟩
Article dans une revue inserm-01856278v1

Synthesis of Polyfused Heterocycle Derivatives Containing the Dipyridoimidazole Core by Friedländer’s Reaction: Access to Analogs of Ellipticine

 Emmanuel Moreau , Jean-Claude Teulade , Nicolas Desbois , Jean-Michel J.-M. Chezal , Florence Fauvelle , et al.
Heterocycles, 2005, 65 (5), ⟨10.3987/COM-05-10354⟩
Article dans une revue hal-01677674v1

Linker structure-activity relationships in fluorodeoxyglucose chlorambucil conjugates for tumor-targeted chemotherapy

 Valérie Weber , Mostafa El Hilali , Bastien Reux , Eric Debiton , Fernand Leal , et al.
Bioorganic and Medicinal Chemistry, 2017, 25 (20), pp.5692 - 5708. ⟨10.1016/j.bmc.2017.08.043⟩
Article dans une revue hal-01677115v1
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[18F]ML-10 PET imaging fails to assess early response to neoadjuvant chemotherapy in a preclinical model of triple negative breast cancer

 Elodie Jouberton , Sébastien Schmitt , Emmanuel Chautard , Aurélie Maisonial-Besset , Marie Roy , et al.
EJNMMI Research, 2020, 10 (1), pp.2. ⟨10.1186/s13550-019-0587-5⟩
Article dans une revue hal-02489788v1
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Antibody PEGylation in bioorthogonal pretargeting with trans-cyclooctene/tetrazine cycloaddition: in vitro and in vivo evaluation in colorectal cancer models

 Aurélie Rondon , Nancy Ty , Jean-Baptiste Bequignat , Mercédès Quintana , Arnaud Briat , et al.
Scientific Reports, 2017, 7 (1), ⟨10.1038/s41598-017-15051-y⟩
Article dans une revue hal-01646770v1

Melanoma-targeted delivery system (part 2): Synthesis, radioiodination and biological evaluation in B16F0 bearing mice

 Emmanuel Moreau , Radhia El Aissi , Imen Miladi , Jean-Michel J.-M. Chezal , Olivier Chavignon , et al.
European Journal of Medicinal Chemistry, 2016, 120, pp.304 - 312. ⟨10.1016/j.ejmech.2016.05.019⟩
Article dans une revue hal-01677545v1

Design, synthesis and preliminary biological evaluation of acridine compounds as potential agents for a combined targeted chemo-radionuclide therapy approach to melanoma

 Nicolas Desbois , Maryline Gardette , Janine Papon , Pierre Labarre , Aurélie Maisonial , et al.
Bioorganic and Medicinal Chemistry, 2008, 16 (16), pp.7671-7690. ⟨10.1016/j.bmc.2008.07.015⟩
Article dans une revue istex hal-01494523v1

Simple and convenient conversion of acridones into 9-unsubstituted acridines via acridanes using borane tetrahydrofuran complex

 Nicolas Desbois , Anna Szollosi , Aurélie Maisonial , Valérie Weber , Emmanuel Moreau , et al.
Tetrahedron Letters, 2009, 50 (49), pp.6894 - 6896. ⟨10.1016/j.tetlet.2009.09.141⟩
Article dans une revue istex hal-01677641v1
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Synthesis and Biological Evaluation of Indoloquinolines and Pyridocarbazoles: A New Example of Unexpected Photoreduction Accompanying Photocyclization

 Pierre-Jean Aragon , Ange-Désiré Yapi , Frédéric Pinguet , Jean-Michel Chezal , Jean-Claude Teulade , et al.
Chemical and Pharmaceutical Bulletin, 2007, 55 (9), pp.1349-1355. ⟨10.1248/cpb.55.1349⟩
Article dans une revue hal-02384499v1

Mise en place de la radiosynthèse de la molécule ICF01012 marquée à l’iode-131 dans la radiopharmacie expérimentale du Centre Jean-Perrin

 Nicolas Hugo , Sophie Levesque , Amandine Egret , Marion Tempier , Marie-Josephe Galmier , et al.
9ème réunion annuelle de l'ITS (Institut des Technologie pour la Santé, Aviesan), Nov 2017, Lyon, France
Poster de conférence hal-01677535v1
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Improved automated one-pot two-step radiosynthesis of (S)-[18F]FETrp, a radiotracer for PET imaging of indoleamine 2,3-dioxygenase 1 (IDO1)

 Aurélie Maisonial-Besset , David Kryza , Klaus Kopka , Sophie Levesque , Emmanuel Moreau , et al.
European Association of Nuclear Medicine, issuing body - EJNMMI radiopharmacy and chemistry, 2024, 9 (1), pp.28. ⟨10.1186/s41181-024-00256-0⟩
Article dans une revue hal-04531511v1

Doxycycline and its quaternary ammonium derivative for adjuvant therapies of chondrosarcoma

 Imen Miladi , Magali Vivier , Marie-Mélanie Dauplat , Morgane Chatard , Sophie Besse , et al.
Cancer Chemotherapy and Pharmacology, 2017, 80 (3), pp.517 - 526. ⟨10.1007/s00280-017-3377-7⟩
Article dans une revue hal-01646771v1
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Synthesis and In Vitro Comparison of DOTA, NODAGA and 15-5 Macrocycles as Chelators for the 64Cu-Labelling of Immunoconjugates

 Aurélie Maisonial-Besset , Tiffany Witkowski , Mercedes Quintana , Sophie Besse , Vincent Gaumet , et al.
Molecules, 2022, 28 (1), pp.75. ⟨10.3390/molecules28010075⟩
Article dans une revue hal-03911093v1

Radiation dosimetry of [ 131 I]ICF01012 in rabbits: Application to targeted radionuclide therapy for human melanoma treatment

 Elodie Jouberton , Yann Perrot , Béatrice Dirat , Tommy Billoux , Philippe Auzeloux , et al.
Medical Physics, 2018, 45 (11), pp.5251 - 5262. ⟨10.1002/mp.13165⟩
Article dans une revue hal-01925049v1

Short and efficient access to imidazo[1,2-a]pyrrolo[3,2-c]pyridine derivatives

 Emmanuel Moreau , Vincent Gaumet , Abbass Taleb , Fernand Leal , Johan Neyts , et al.
Tetrahedron Letters, 2010, 51 (47), pp.6082 - 6085. ⟨10.1016/j.tetlet.2010.09.056⟩
Article dans une revue istex hal-01677637v1
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Design, synthesis and evaluation of targeted hypoxia-activated prodrugs applied to chondrosarcoma chemotherapy

 Yvain Gerard , Aurélien Voissiere , Caroline Peyrode , Marie-Josephe Galmier , Elise Maubert , et al.
Bioorganic Chemistry, 2020, 98, pp.103747. ⟨10.1016/j.bioorg.2020.103747⟩
Article dans une revue hal-02866765v1

Design, synthesis and in vitro drug release investigation of new potential 5-FU prodrugs

 Pierre Daumar , Caroline Decombat , Jean-Michel Chezal , Eric Debiton , Michel Madesclaire , et al.
European Journal of Medicinal Chemistry, 2011, 46 (7), pp.2867-2879. ⟨10.1016/j.ejmech.2011.04.010⟩
Article dans une revue istex hal-03121824v1

Evaluation of two I-125-radiolabeled acridine derivatives for Auger-electron radionuclide therapy of melanoma

 Maryline Gardette , Claire Viallard , Salomé Paillas , Jean-Luc Guerquin-Kern , Janine Papon , et al.
Investigational New Drugs, 2014, 32 (4), pp.587-597. ⟨10.1007/s10637-014-0086-5⟩
Article dans une revue hal-01456424v1

Evaluation of the active targeting of melanin granules after intravenous injection of dendronized nanoparticles

 Catalina Bordeianu , Audrey Parat , Sébastien Piant , Aurélie Walter , Christine Zbaraszczuk-Affolter , et al.
Molecular Pharmaceutics, 2018, ⟨10.1021/acs.molpharmaceut.7b00904⟩
Article dans une revue hal-01680955v1
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99mTc-NTP 15-5 assessment of the early therapeutic response of chondrosarcoma to zoledronic acid in the Swarm rat orthotopic model.

 Elisabeth Miot-Noirault , Emmanuelle David , Aurélien Vidal , Caroline Peyrode , Sophie Besse , et al.
EJNMMI Research, 2013, 3 (1), pp.40. ⟨10.1186/2191-219X-3-40⟩
Article dans une revue inserm-00827007v1
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Synthesis and in Vitro Cytotoxic Evaluation of New Derivatives of Pyrido[1,2-a]benzimidazolic Ring System: The Pyrido[1,2:1,2]imidazo[4,5-h]quinazolines

 Marianne Dupuy , Frédéric Pinguet , Olivier Chavignon , Jean-Michel Chezal , Jean-Claude Teulade , et al.
Chemical and Pharmaceutical Bulletin, 2001, 49, pp.1061 - 1065. ⟨10.1248/cpb.49.1061⟩
Article dans une revue hal-02384513v1
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Development of a new radiofluorinated quinoline analog for PET imaging of phosphodiesterase 5 (PDE5) in brain

 Jianrong Liu , Barbara Wenzel , Sladjana Dukic-Stefanovic , Rodrigo Teodoro , Friedrich-Alexander Ludwig , et al.
Pharmaceuticals, 2016, 9 (2), pp.22. ⟨10.3390/ph9020022⟩
Article dans une revue hal-01677542v1

Synthesis, radiolabeling and preliminary in vivo evaluation of multimodal radiotracers for PET imaging and targeted radionuclide therapy of pigmented melanoma

 Aurélie Maisonial-Besset , Emilie M.F. Billaud , Aurélie Besse , Latifa Vidal , Aurélien Vidal , et al.
European Journal of Medicinal Chemistry, 2015, 92, pp.818 - 838. ⟨10.1016/j.ejmech.2015.01.034⟩
Article dans une revue hal-01677566v1

Proteoglycans as Target for an Innovative Therapeutic Approach in Chondrosarcoma: Preclinical Proof of Concept

 Caroline Peyrode , Valérie Weber , A. Voissiere , A. Maisonial-Besset , A. Vidal , et al.
Molecular Cancer Therapeutics, 2016, 15 (11), pp.2575 - 2585. ⟨10.1158/1535-7163.MCT-16-0003⟩
Article dans une revue hal-01636341v1
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Intramolecular Cyclization of N-phenyl N'(2-chloroethyl)ureas leads to Active N-phenyl-4,5-dihydrooxazol-2-amines Alkylating β-Tubulin Glu198 and Prohibitin Asp40

 Anna Trzeciakiewicz , Sébastien Fortin , Emmanuel Moreau , René C. Gaudreault , Jacques Lacroix , et al.
Biochemical Pharmacology, 2011, 81 (9), pp.1116- 1123. ⟨10.1016/j.bcp.2011.02.014⟩
Article dans une revue hal-00685075v1
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Targeted Radionuclide Therapy Decreases Melanoma Lung Invasion by Modifying Epithelial-Mesenchymal Transition-Like Mechanisms

 Hussein Akil , Jacques Rouanet , Claire Viallard , Sophie Besse , Philippe Auzeloux , et al.
Translational Oncology, 2019, 12 (11), pp.1442-1452. ⟨10.1016/j.tranon.2019.07.015⟩
Article dans une revue hal-02343369v1

Targeted hypoxia-activated phosphoramide mustards toward tumor proteoglycans in chondrosarcoma

 Yvain Gerard , Aurélien Voissiere , Françoise Rédini , Caroline Peyrode , Françoise Degoul , et al.
CONGRES GP2A-JFB 2018, Jun 2018, ASNELLE SUR MER, France
Communication dans un congrès hal-01938962v1

Small rigid platforms functionalization with quaternary ammonium: Targeting extracellular matrix of chondrosarcoma

 Elisabeth Miot-Noirault , Aurélien Vidal , Jessica Morlieras , Pauline Bonazza , Philippe Auzeloux , et al.
Nanomedicine: Nanotechnology, Biology and Medicine, 2014, 10 (8), pp.1887-1895. ⟨10.1016/j.nano.2014.06.011⟩
Article dans une revue hal-01115673v1
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Structure-activity relationship study of hypoxia-activated prodrugs for proteoglycan-targeted chemotherapy in chondrosarcoma

 Donia Ghedira , Aurélien Voissiere , Caroline Peyrode , Jamil Kraiem , Yvain Gerard , et al.
European Journal of Medicinal Chemistry, 2018, 158, pp.51 - 67. ⟨10.1016/j.ejmech.2018.08.060⟩
Article dans une revue hal-01926337v1
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