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HIV-1 Nucleocapsid Proteins as Molecular Chaperones for Tetramolecular Antiparallel G-Quadruplex Formation

Arivazhagan Rajendran , Masayuki Endo , Kumi Hidaka , Phong Lan Thao Tran , Jean-Louis Mergny , et al.
Journal of the American Chemical Society, 2013, 135 (49), pp.18575-18585. ⟨10.1021/JA409085J⟩
Article dans une revue mnhn-02619253v1
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Quadruplex Turncoats: Cation-Dependent Folding and Stability of Quadruplex-DNA Double Switches

Eric Largy , Adrien Marchand , Samir Amrane , Valérie Gabelica , Jean-Louis Mergny
Journal of the American Chemical Society, 2016, 138 (8), pp.2780-2792. ⟨10.1021/jacs.5b13130⟩
Article dans une revue hal-01524154v1

Targeting nucleolin by RNA G-quadruplex-forming motif

Joana Figueiredo , André Miranda , Jéssica Lopes-Nunes , Josué Carvalho , Daniela Alexandre , et al.
Biochemical Pharmacology, 2021, 189, pp.114418. ⟨10.1016/j.bcp.2021.114418⟩
Article dans une revue hal-03119214v1

Highly Sensitive Biosensing Applications of a Magnetically Immobilizable Covalent G-Quadruplex-Hemin DNAzyme Catalytic System

Yun Chen , Dehui Qiu , Xiaobo Zhang , Yuan Liu , Mingpan Cheng , et al.
Analytical Chemistry, 2022, 94 (2212-2219), pp.acs.analchem.1c04842. ⟨10.1021/acs.analchem.1c04842⟩
Article dans une revue hal-03539454v1
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hnRNPA1/UP1 Unfolds KRAS G-Quadruplexes and Feeds a Regulatory Axis Controlling Gene Expression

Annalisa Ferino , Julien Marquevielle , Himanshi Choudhary , Giorgio Cinque , Coralie Robert , et al.
ACS Omega, 2021, 6 (49), pp.34092-34106. ⟨10.1021/acsomega.1c05538⟩
Article dans une revue hal-03504886v1
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Triple helix formation with Drosophila satellite repeats. Unexpected stabilization by copper ions.

Virginie Horn , Laurent Lacroix , Thierry Gautier , Masashi Takasugi , Jean-Louis Mergny , et al.
Biochemistry, 2004, 43 (35), pp.11196-205. ⟨10.1021/bi049287t⟩
Article dans une revue inserm-00335093v1
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SARS-CoV-2 Nsp3 unique domain SUD interacts with guanine quadruplexes and G4-ligands inhibit this interaction

Marc Lavigne , Olivier Helynck , Pascal Rigolet , Rofia Boudria-Souilah , Mireille Nowakowski , et al.
Nucleic Acids Research, 2021, 49 (13), pp.7695-7712. ⟨10.1093/nar/gkab571⟩
Article dans une revue hal-03281130v1

A mirror-image tetramolecular DNA quadruplex

Phong Lan Thao Tran , Rui Moriyama , Atsushi Maruyama , Bernard Rayner , Jean-Louis Mergny
Chemical Communications, 2011, 47 (19), pp.5437. ⟨10.1039/c1cc11293g⟩
Article dans une revue mnhn-02619123v1

Analyses of viral genomes for G-quadruplex forming sequences reveal their correlation with the type of infection

Natália Bohálová , Alessio Cantara , Martin Bartas , Patrik Kaura , Jiří Šťastný , et al.
Biochimie, 2021, 186, pp.13-27. ⟨10.1016/j.biochi.2021.03.017⟩
Article dans une revue hal-03193949v1
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Human papillomavirus G-rich regions as potential antiviral drug 1 targets

Josué Carvalho , Jéssica Lopes-Nunes , Maria P C Campello , António Paulo , Janice Milici , et al.
Nucleic Acid Therapeutics, In press
Article dans une revue inserm-02958829v1
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Highly efficient radiosensitization of human glioblastoma and lung cancer cells by a G-quadruplex DNA binding compound

Patrick Merle , Marine Gueugneau , Marie-Paule Teulade-Fichou , Mélanie Müller-Barthélémy , Simon Amiard , et al.
Scientific Reports, 2015, 5 (1), ⟨10.1038/srep16255⟩
Article dans une revue inserm-01907350v1
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Design, synthesis, and antiprotozoal evaluation of new 2,4-bis[(substituted-aminomethyl)phenyl]quinoline, 1,3-bis[(substituted-aminomethyl)phenyl]isoquinoline and 2,4-bis[(substituted-aminomethyl)phenyl]quinazoline derivatives

Jean Guillon , Anita Cohen , Clotilde Boudot , Alessandra Valle , Vittoria Milano , et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2020, 35 (1), pp.432-459. ⟨10.1080/14756366.2019.1706502⟩
Article dans une revue hal-02428661v1

Design, synthesis, and antiprotozoal evaluation of new 2,9-bis[(substituted-aminomethyl)phenyl]-1,10-phenanthroline derivatives

Jean Guillon , Anita Cohen , Rabindra Nath Das , Clotilde Boudot , Nassima Meriem Gueddouda , et al.
Chemical Biology & Drug Design, 2018, ⟨10.1111/cbdd.13164⟩
Article dans une revue hal-01690455v1

The nickel(II) complex of guanidinium phenyl porphyrin, a specific G-quadruplex ligand, targets telomeres and leads to POT1 mislocalization in culture cells

Laurent Sabater , Marie-Laure Nicolau-Travers , Aurore de Rache , Enora Prado , Jérôme Dejeu , et al.
Journal of Biological Inorganic Chemistry, 2015, 20 (4), pp.729 - 738. ⟨10.1007/s00775-015-1260-8⟩
Article dans une revue hal-01651420v1
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Activation of the Ataxia Telangiectasia Mutated/Autophagy pathway by a G-quadruplex ligand links senescence with apoptosis

Jennifer Beauvarlet , Jean‐louis Mergny , Mojgan Djavaheri-Mergny
Molecular & Cellular Oncology, 2019, 6 (4), pp.1604047. ⟨10.1080/23723556.2019.1604047⟩
Article dans une revue inserm-03653049v1
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Thermal and pH stabilities of i-DNA: confronting in vitro experiments with models and in-cell NMR data

Mingpan Cheng , Dehui Qiu , Liezel Tamon , Eva Ištvánková , Pavlína Víšková , et al.
Angewandte Chemie International Edition, 2021, 60, pp.10286-10294. ⟨10.1002/anie.202016801⟩
Article dans une revue hal-03149390v1

G-quadruplex-binding ligand-induced DNA synapsis inside a DNA origami frame

Arivazhagan Rajendran , Masayuki Endo , Kumi Hidaka , Phong Lan Thao Tran , Marie-Paule Teulade-Fichou , et al.
RSC Advances, 2014, 4 (12), pp.6346. ⟨10.1039/C3RA45676E⟩
Article dans une revue mnhn-02619279v1

Effects of 8-methylguanine on structure, stability and kinetics of formation of tetramolecular quadruplexes

Phong Lan Thao Tran , Antonella Virgilio , Veronica Esposito , Giuseppe Citarella , Jean-Louis Mergny , et al.
Biochimie, 2011, 93 (3), pp.399-408. ⟨10.1016/j.biochi.2010.10.011⟩
Article dans une revue istex mnhn-02619091v1

Plasmodium Telomeric Sequences: Structure, Stability and Quadruplex Targeting by Small Compounds

Anne de Cian , Philippe Grellier , Elisabeth Mouray , Delphine Depoix , Hélène Bertrand , et al.
ChemBioChem, 2008, 9 (16), pp.2730-2739. ⟨10.1002/cbic.200800330⟩
Article dans une revue hal-02125633v1

The importance of metal geometry in the recognition of G-quadruplex-DNA by metal-terpyridine complexes.

Hélène Bertrand , David Monchaud , Anne de Cian , Régis Guillot , Jean-Louis Mergny , et al.
Organic & Biomolecular Chemistry, 2007, 5 (16), pp.2555-9
Article dans une revue hal-00259076v1

G-quadruplex DNA targeting alters class-switch recombination in B cells and attenuates allergic inflammation

Zeinab Dalloul , Pauline Chenuet , Iman Dalloul , François Boyer , Jean-Claude Aldigier , et al.
Journal of Allergy and Clinical Immunology, 2018, 142 (4), pp.1352-1355. ⟨10.1016/j.jaci.2018.06.011⟩
Article dans une revue hal-02343989v1
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The Newly Sequenced Genome of Pisum sativum Is Replete with Potential G-Quadruplex-Forming Sequences—Implications for Evolution and Biological Regulation

Michaela Dobrovolná , Natália Bohálová , Vratislav Peška , Jiawei Wang , Yu Luo , et al.
International Journal of Molecular Sciences, 2022, 23 (15), pp.8482. ⟨10.3390/ijms23158482⟩
Article dans une revue hal-04387362v1
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The exception that confirms the rule: a higher-order telomeric G-quadruplex structure more stable in sodium than in potassium

Carole Saintomé , Samir Amrane , Jean-Louis Mergny , Patrizia Alberti
Nucleic Acids Research, 2016, 44 (6), pp.2926-2935. ⟨10.1093/nar/gkw003⟩
Article dans une revue hal-01327389v1

Quadruplexes in ‘Dicty’: crystal structure of a four-quartet G-quadruplex formed by G-rich motif found in the Dictyostelium discoideum genome

Aurore Guédin , Linda Yingqi Lin , Samir Armane , Laurent Lacroix , Jean-Louis Mergny , et al.
Nucleic Acids Research, 2018, 46 (10), pp.5297-5307. ⟨10.1093/nar/gky290⟩
Article dans une revue hal-02472337v1
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G-quadruplexes and helicases

Oscar Mendoza , Anne Bourdoncle , Jean-Baptiste Boulé , Robert M Brosh , Jean-Louis Mergny
Nucleic Acids Research, 2016, 44 (5), pp.1989-2006. ⟨10.1093/nar/gkw079⟩
Article dans une revue hal-02305798v1
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Highly efficient radiosensitization of human glioblastoma and lung cancer cells by a G-quadruplex DNA binding compound

Patrick Merle , Marine Gueugneau , Marie-Paule Teulade-Fichou , Mélanie Müller-Barthélémy , Simon Amiard , et al.
Scientific Reports, 2015, 5 (1), ⟨10.1038/srep16255⟩
Article dans une revue hal-01812829v1
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Insights into G-Quadruplex–Hemin Dynamics Using Atomistic Simulations: Implications for Reactivity and Folding

Petr Stadlbauer , Barira Islam , Michal Otyepka , Jielin Chen , David Monchaud , et al.
Journal of Chemical Theory and Computation, 2021, 17 (3), pp.1883 - 1899. ⟨10.1021/acs.jctc.0c01176⟩
Article dans une revue hal-03200900v1

Recognition of G‐Quadruplex DNA by Triangular Star‐Shaped Compounds: With or Without Side Chains?

Hélène Bertrand , Anton Granzhan , David Monchaud , Nicolas Saettel , Régis Guillot , et al.
Chemistry - A European Journal, 2011, 17 (16), pp.4529-4539. ⟨10.1002/chem.201002810⟩
Article dans une revue istex hal-02125704v1

2,6-Diphenylthiazolo[3,2-b][1,2,4]triazoles as telomeric G-quadruplex stabilizers

Jamal El Bakali , Frédérique Klupsch , Aurore Guédin , Bertrand Brassart , Gaëlle Fontaine , et al.
Bioorganic and Medicinal Chemistry Letters, 2009, 19 (13), pp.3434 - 3438. ⟨10.1016/j.bmcl.2009.05.025⟩
Article dans une revue istex hal-01817465v1
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G-quadruplex ligands as potent regulators of lysosomes

Lucille Ferret , Karla Alvarez-Valadez , Jennifer Rivière , Alexandra Muller , Natalia Bohálová , et al.
Autophagy, 2023, 19 (7), pp.1901-1915. ⟨10.1080/15548627.2023.2170071⟩
Article dans une revue inserm-03974582v1