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Jean-Jacques LAREYRE

9
Documents
Identifiants chercheurs

Présentation

My research aim to better understand molecular mechanisms underlying the sexual maturation (puberty) in fish, particularly in male. The initiation of the male gametogenesis (spermatogenesis) is an important biological process that impacts puberty onset and ultimately fish fertility. Puberty onset depends on the activation of the gonadotrope axis (GnRHs) that ultimately control the release from the pituitary of two gonadotropins named FSH and LH. Both hormones control the two main testicular functions (spermatogeneis and steroidogenesis). Spermatogeneis relies on the balance between renewal and proliferation/differentiation of germ stem cells. The role of the sexual hormones (gonadotropins and gonadotropin induced sexual steroids) in the regulation of this balance remains poorly understood. My basic research aims to : - characterize the molecular profile of adult germ stem cells in teleost fish species - characterize gonadal factors that may be involved in the regulation of germ stem cell fate (germ stem cell renewal or germline differentiation) - understanding the molecular mechanisms underlying the distinct effects of the sexual hormones (steroids and gonadotropins) My applied research aims to : - improve the practicability of germ stem cell grafting - develop early markers of precocious puberty

Publications

yann-guiguen
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Characterization of rainbow trout gonad, brain and gill deep cDNA repertoires using a Roche 454-Titanium sequencing approach

Aurélie Le Cam , Julien Bobe , Olivier Bouchez , Cédric Cabeau , Olivier Kah
Gene, 2012, 500 (1), pp.32-39. ⟨10.1016/j.gene.2012.03.053⟩
Article dans une revue hal-01205069v1

Expression of sGnRH mRNA in gonads during rainbow trout gametogenesis.

Svetlana Uzbekova , Jean-Jacques Lareyre , Yann Guiguen , F. Ferriere , T. Bailhache
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 2001, 129 (2-3), pp.457-465. ⟨10.1016/S1096-4959(01)00347-5⟩
Article dans une revue hal-02672221v1

Type II iodothyronine deiodinase is preferentially expressed in rainbow trout (Oncorhynchus mykiss) liver and gonads

Elisabeth Sambroni , Stéphanie Gutieres , Chantal Cauty , Yann Guiguen , Bernard Breton
Molecular Reproduction and Development, 2001, 60, pp.338-350. ⟨10.1002/mrd.1096⟩
Article dans une revue hal-02674878v1

Stage-dependent and alternative splicing of sGnRH messengers in rainbow trout testis during spermatogenesis.

Svetlana Uzbekova , F. Ferriere , Yann Guiguen , T. Bailhache , Bernard Breton
Molecular Reproduction and Development, 2001, 59, pp.1-10. ⟨10.1002/mrd.1000⟩
Article dans une revue hal-02679721v1

DMRT1 expression during gonadal differentiation and spermatogenesis in the rainbow, Oncorhynchus mykiss.

O. Marchand , M. Govoroun , H. d'Cotta , Jean-Jacques Lareyre , A. Bernot
BBA - Biochimica et Biophysica Acta, 2000, 1493, pp.180-187
Article dans une revue hal-00023770v1

DMRT1 expression during gonadal differentiation and spermatogenesis in the rainbow trout, Oncorhynchus mykiss

O. Marchand , Marina Govoroun , Helena d'Cotta , Oonagh Mcmeel , Jean-Jacques Lareyre
BBA - Biochimica et Biophysica Acta, 2000, 1493, pp.180-187. ⟨10.1016/S0167-4781(00)00186-X⟩
Article dans une revue hal-02696792v1

Expression of cytochrome P450 11B (11beta-hydrolase) gene during gonadal sex differentiation and spermatogenesis in rainbow trout, Oncorhynchus mykiss

Shaojun Liu , Marina Govoroun , Helena d'Cotta , Marie-José Ricordel , Jean-Jacques Lareyre
Journal of Steroid Biochemistry and Molecular Biology, 2000, 75, pp.291-298. ⟨10.1016/S0960-0760(00)00186-2⟩
Article dans une revue hal-02683926v1

La reproduction des poissons

Julien Bobe , Alexis Fostier , Yann Guiguen , Jean-Jacques Lareyre , Florence Le Gac
La reproduction animale et humaine, Editions Quae, 751 p., 2014, Collection Synthèses, 978-2-7592-2208-7
Chapitre d'ouvrage hal-01205108v1

Sexualité et reproduction

Julien Bobe , Bernard Breton , Alexis Fostier , Yann Guiguen , Bernard Jalabert
La truite arc-en-ciel. De la biologie à l'élevage, Editions Quae, 2010, Synthèses, 978-2-7592-0875-3
Chapitre d'ouvrage hal-01193565v1