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Size effects on amorphous crystallization kinetics: Constraints imposed by nucleation and growth specificities

 Marc Descamps , Jean-François Willart
JMC 2018, Jjournées de la Matière Condensée, Grenoble (27-31 août 2018), 2018, Grenoble, France
Communication dans un congrès hal-04510732v1

Efficient solid state transformation protocol to determine the solubility of drugs into polymers

 Mansour Latreche , Jean-François Willart , Alain Hedoux
The 1st International Conference on Contemporary Pharmacy Challenges, Sep 2018, Wisla, Poland
Communication dans un congrès hal-02333509v1

Structural investigation of amorphous lactulose by neutron diffraction experiment

 Frederic Affouard , Jean-François Willart , Frédéric Ngono Mebenga , Gabriel J. Cuello , Monica Jimenez-Ruiz
Analysis of Diffraction Data in Real Space (ADD2016), Mar 2016, Grenoble, France
Poster de conférence hal-02318533v1

Investigations of physical properties of amorphous materials using neutron scattering experiments

 Frederic Affouard , Jean-François Willart , Frédéric Ngono Mebenga , G.J. Cuello , M. Jimenez-Ruiz
Journées de la Diffusion Neutronique (JDN2017), May 2017, Carry le Rouet, France
Communication dans un congrès hal-02318059v1

Etude in-situ de composés moléculaires sous broyage à haute énergie: de l'amorphisation à la transformation à l'état solide

 Pierre Bordet , Pauline Martinetto , William Pagnoux , Jean-François Willart , Marc Descamps , et al.
AFC 2018 (16th European Powder Diffraction Conference), 2018, Lyon, France
Communication dans un congrès hal-04512515v1

Cinétique de transformation de phase de produits pharmaceutiques sous broyage

 Anthony Dupont , Mathieu Guerain , Jean-François Willart
Conférence International Matériaux 2022, 2022, Lille, France
Poster de conférence hal-04516264v1
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High energy ball milling vs. nano spray drying in the development of supersaturated systems loaded with bosentan

 Anna Krupa , Florence Danede , Dorota Majda , Agnieszka Węgrzyn , Dominik Strojewski , et al.
European Journal of Pharmaceutics and Biopharmaceutics, 2023, European Journal of Pharmaceutics and Biopharmaceutics, 188, pp.137-146. ⟨10.1016/j.ejpb.2023.05.014⟩
Article dans une revue hal-04278637v1
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The implication of the lattice in the non-equilibrium behaviour of a glassy crystal

 Michel Descamps , Jean-François Willart , G. Odou , K. Eichhorn
Journal de Physique I, 1992, 2 (6), pp.813-827. ⟨10.1051/jp1:1992181⟩
Article dans une revue istex jpa-00246603v1
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Structure determination of riboflavin by synchrotron high-resolution powder X-ray diffraction

 Mathieu Guerain , Frédéric Affouard , Charline Henaff , Catherine Dejoie , Florence Danede , et al.
Acta Crystallographica Section C : Structural Chemistry [2014-..], 2021, 77 (12), pp.800-806. ⟨10.1107/s2053229621012171⟩
Article dans une revue hal-03469379v1

Amorphization and solubility enhancement: the peculiar case of chlorhexidine free base

 Charline Henaff , Juergen Siepmann , Florence Siepmann , Jean-François Willart
17th PSSRC: Pharmaceutical Solid State Research Cluster, 2023, Cambridge (GB), United Kingdom
Communication dans un congrès hal-04509160v1

Evidence of a two-stage thermal denaturation process in lysozyme: A Raman scattering and differential scanning calorimetry investigation

 Alain Hédoux , R. Ionov , Jean-François Willart , Adrien Lerbret , Frederic Affouard , et al.
Journal of Chemical Physics, 2006, 124 (1), pp.014703. ⟨10.1063/1.2139087⟩
Article dans une revue hal-02972262v1
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Evidence of transient amorphization during the polymorphic transformation of sorbitol induced by milling

 Anthony Dupont , Mathieu Guerain , Florence Danede , Jean-François Willart
International Journal of Pharmaceutics, 2022, International Journal of Pharmaceutics, pp.121929. ⟨10.1016/j.ijpharm.2022.121929⟩
Article dans une revue hal-03707238v1
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Contribution of low-frequency Raman spectroscopy to determine the solubility curves of drugs in polymers: The case of paracetamol/PVP

 Mansour Latreche , Jean-François Willart , Laurent Paccou , Yannick Guinet , Florence Danede , et al.
European Journal of Pharmaceutics and Biopharmaceutics, 2020, European Journal of Pharmaceutics and Biopharmaceutics, 154, pp.222-227. ⟨10.1016/j.ejpb.2020.07.012⟩
Article dans une revue hal-02967672v1

Using Milling To Explore Physical States: The Amorphous and Polymorphic Forms of Dexamethasone

 Paulo F. M. Oliveira , Jean-François Willart , Juergen Siepmann , Florence Siepmann , Marc Descamps
Crystal Growth & Design, 2018, Crystal Growth & Design, 18, pp.1748-1757. ⟨10.1021/acs.cgd.7b01664⟩
Article dans une revue hal-02333436v1
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Exploration of the physical states of riboflavin (free base) by mechanical milling

 Charline Henaff , Juergen Siepmann , Florence Siepmann , Florence Danede , Marie-Noëlle Avettand-Fènoël , et al.
International journal of pharmaceutics , 2023, International journal of pharmaceutics, 645, pp.123416. ⟨10.1016/j.ijpharm.2023.123416⟩
Article dans une revue hal-04214667v1

Scaling laws and size effects for amorphous crystallization kinetics: Constraints imposed by nucleation and growth specificities

 Marc Descamps , Jean-François Willart
International Journal of Pharmaceutics, 2018, International journal of pharmaceutics, 542, pp.186-195. ⟨10.1016/j.ijpharm.2018.03.001⟩
Article dans une revue hal-02333424v1

Analysis of Sugar Bioprotective Mechanisms on the Thermal Denaturation of Lysozyme from Raman Scattering and Differential Scanning Calorimetry Investigations

 Alain Hédoux , Jean-François Willart , R. Ionov , Frederic Affouard , Yannick Guinet , et al.
Journal of Physical Chemistry B, 2006, 110 (45), pp.22886-22893. ⟨10.1021/jp061568i⟩
Article dans une revue istex hal-02972127v1
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PLGA implants for controlled dexamethasone delivery: Impact of the polymer chemistry

 S. Wachowiak , Florence Danede , Jean-François Willart , F. Siepmann , J. Siepmann , et al.
Journal of Drug Delivery Science and Technology, 2023, Journal of Drug Delivery Science and Technology, 86, pp.104648. ⟨10.1016/j.jddst.2023.104648⟩
Article dans une revue hal-04297225v2

Apport de la DSC à modulation de température pour l'étude des matériaux pharmaceutiques amorphes

 Jean-François Willart
Journée des utilisateurs TA Instruments, 2019, Paris, France
Communication dans un congrès hal-04510723v1

Amorphous Solid Dispersions : Interest, production and stability

 Jean-François Willart
Séminaire de recherche de l'entreprise Roquette, 2023, Lestrem, France
Communication dans un congrès hal-04510970v1

Can a dissolution enthalpy value be used as an absolute indicator to assess rehydration behaviour and ageing of food powders?

 Romain Jeantet , Ousmane Syll , Bruno Richard , Jean-François Willart , Marc Descamps , et al.
IDS 2012 18. Symposium in the biennial series of International Drying Symposia séries (IDS), Dec 2012, Xiamen Fujian, China
Communication dans un congrès hal-01209369v1

Solid state transformations of pharmaceuticals induced by milling: Experimental and numerical kinetics investigations

 Jean-François Willart , Pierre Bordet , Pauline Martinetto , Emeline Dudognon , Juergen Siepmann , et al.
INCOME 2020 (9th International Conference on Mechanochemistry and Mechanical Alloying, 2020, Cagliari, Italy
Communication dans un congrès hal-04512512v1
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Impact of amorphisation methods on the physico-chemical properties of amorphous lactulose

 Frederic Ngono , Jean-François Willart , Gabriel J. Cuello , Monica Jimenez-Ruiz , Mounira Hamoudi , et al.
Molecular Pharmaceutics, 2020, Molecular Pharmaceutics, 17, pp.1-9. ⟨10.1021/acs.molpharmaceut.9b00740⟩
Article dans une revue hal-02353960v3

Etude PDF de l’amorphisation du beta−tréhalose induite par broyage haute énergie

 Pierre Bordet , Pauline Martinetto , William Pagnoux , Emeline Dudognon , Jean-Francois Willart
Rayons X et Matière, Dec 2015, Grenoble, France
Communication dans un congrès hal-01994346v1
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Morphological and structural properties of amorphous lactulose studied by scanning electron microscopy, polarised neutron scattering, and molecular dynamics simulations

 Frederic Ngono , Gabriel J. Cuello , Monica Jimenez-Ruiz , Jean-François Willart , Mathieu Guerain , et al.
Molecular Pharmaceutics, 2020, Molecular Pharmaceutics, 17, pp.10-20. ⟨10.1021/acs.molpharmaceut.9b00767⟩
Article dans une revue hal-03011581v1
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Long term behavior of dexamethasone-loaded cochlear implants: In vitro & in vivo

 T. Rongthong , Adam Qnouch , M. M. Gehrke , Florence Danede , Jean-François Willart , et al.
International Journal of Pharmaceutics: X, 2022, International Journal of Pharmaceutics: X, 4, pp.100141. ⟨10.1016/j.ijpx.2022.100141⟩
Article dans une revue hal-04013479v1
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Lactulose: a model system to investigate solid state amorphization induced by milling

 Frédéric Ngono Mebenga , Jean-François Willart , Gabriel J. Cuello , Monica Jimenez-Ruiz , Frederic Affouard
Journal of Pharmaceutical Sciences, 2019, Journal of Pharmaceutical Sciences, 108, pp.880-887. ⟨10.1016/j.xphs.2018.09.013⟩
Article dans une revue hal-02318062v1

Investigations of physical properties of amorphous materials obtained from different routes

 Frederic Affouard , Jean-François Willart , Frédéric Ngono Mebenga , G.J. Cuello , M. Jimenez-Ruiz
8th International Discussion Meeting on Relaxations in Complex Systems (8IDMRCS), Jul 2017, Wisla, Poland
Communication dans un congrès hal-02318057v1

PDF Investigation of the Crystal to Glass Transformation of −trehalose Induced by Milling

 Pierre Bordet , William Pagnoux , Pauline Martinetto , Jean-Francois Willart , Emeline Dudognon
Condensed Matter in Paris, Aug 2014, Paris, France
Communication dans un congrès hal-01994319v1

In-situ powder diffraction study of molecular compounds under high energy milling: from amorphization to solid state transformation

 Pierre Bordet , Pauline Martinetto , Jean-François Willart , Marc Descamps , Emeline Dudognon
EPDIC 16 (16th European Powder Diffraction Conference), Jul 2018, Edimbourg, United Kingdom
Communication dans un congrès hal-01994355v1
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