Jean-François Brière (06/06/1971) - CNRS senior research scientist
Laboratory COBRA (Organic Chemistry Bioorganic Reactivity and Analysis)
University of Rouen Normandy, IRCOF building (UMR CNRS 6014, INSA Rouen Normandy)
1, rue Tesnière, 76821 Mont Saint Aignan (France)
▪ Email: jean-francois.briere@insa-rouen.fr, Tel: +33(0)235522464
▪ Website: (www.lab-cobra.fr/equipes/heterocycles, CatCH group)
▪ ResearcherID: Q-8910-2016; ORCID: 0000-0002-1381-4535
▪ 66 publications, 6 book chapters, 5 patents
• 1998 Ph.D. in organic chemistry – University of Rouen Normandy - France (3 years), ▪ HETEROCYCLIC AND SUPRAMOLECULAR CHEMISTRY: “synthesis of an artificial enzyme to activate the amide bond construction”
• 1999 Post-doc in the Netherland (18 month), ▪ TOTAL SYNTHESIS: “total synthesis towards solanoeclepin A”
• 2001 Post-doc in Belgium (15 month), ▪ In collaboration with the company Rhodia Silicones at Lyon ▪ CATALYSE: "hydrosilylation catalyzed by Pt-NHC complexes”
independent researcher
BIORELEVANT CHIRAL HETEROCYCLES, ASYMMETRIC SYNTHESIS, (ORGANO)CATALYSIS, NOVEL BUILDING BLOCKS AND REACTIVITY IN ORGANIC SYNTHESIS
• 2002 R&D researcher for pharmaceutical company in France
▪ Research center of RHODIA Company (currently Solvay) at Lyon (France).
• 2002-07 CNRS research scientist CNRS at LCMT laboratory, Univ. Caen Normandy
▪ Habilitation in 2007
▪ Phosphorous & Sulfur team, University of Caen Normandy (France)
▪ Asymmetric sulfur ylide epoxidation reaction.
▪ Novel chiral sulfur heterocycles and odorant properties
• 2007 Heterocycles team (group CatCH) at COBRA laboratory, Univ. and INSA of Rouen Normandy (France), UMR CNRS 6014
▪ Promoted CNRS senior research scientist in 2017
▪ Group leader of team CatCH (Catalysis, Chirality and Heterocycles)
▪ Involved in industrial partnerships (2 joint laboratories, platform and Carnot institute I2C)
▪ Chemistry of biorelevant chiral heterocycles
▪ (Organo)Catalysis and asymmetric synthesis
▪ Domino and multicomponent methodology in sustainable synthesis
▪ Reactivity and useful platform molecules in organic synthesis:
(Meldrum’s acid, triazines, isoxazolidin-5-ones: β-amino acid precursors)