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A Conserved uORF Regulates APOBEC3G Translation and Is Targeted by HIV-1 Vif Protein to Repress the Antiviral Factor

Camille Libre , Tanja Seissler , Santiago Guerrero , Julien Batisse , Cédric Verriez , et al.
Biomedicines, 2021, 10 (1), pp.13. ⟨10.3390/biomedicines10010013⟩
Article dans une revue hal-03519994v1

Molecular architecture and dynamics of ASH1 mRNA recognition by its mRNA-transport complex

Franziska Theresia Edelmann , Andreas Schlundt , Roland Gerhard Heym , Andreas Jenner , Annika Niedner-Boblenz , et al.
Nature Structural and Molecular Biology, 2017, 24 (2), pp.152-161. ⟨10.1038/nsmb.3351⟩
Article dans une revue hal-02171297v1

RNAand DNA binding properties of HIV-1 VIF protein:a fluorescence study.

Serena Bernacchi , Simon Henriet , Philippe Dumas , Jean-Christophe Paillart , Roland Marquet
Journal of Biological Chemistry, 2007, epub ahead of print. ⟨10.1074/jbc.M703122200⟩
Article dans une revue hal-00167513v1
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Structural maturation of the HIV-1 RNA 5' untranslated region by Pr55 Gag and its maturation products

Orian Gilmer , Elodie Mailler , Jean-Christophe Paillart , Assia Mouhand , Carine Tisné , et al.
RNA Biology, 2022, 19 (1), pp.191-205. ⟨10.1080/15476286.2021.2021677⟩
Article dans une revue hal-03599338v1

HIV-1 Vif binds to APOBEC3G mRNA and inhibits its translation.

Gaëlle Mercenne , Serena Bernacchi , Delphine Richer , Guillaume Bec , Simon Henriet , et al.
Nucleic Acids Research, 2010, 38 (2), pp.633-46. ⟨10.1093/nar/gkp1009⟩
Article dans une revue hal-00451267v1
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HIV-1 viral infectivity factor interacts with microtubule-associated protein light chain 3 and inhibits autophagy

Sophie Borel , Véronique Robert-Hebmann , Jamal Alfaisal , Ashish Jain , Mathias Faure , et al.
AIDS. Official journal of the international AIDS Society, 2015, 29 (3), pp.275-286. ⟨10.1097/QAD.0000000000000554⟩
Article dans une revue hal-02421817v1
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The HIV-1 Nucleocapsid Regulates Its Own Condensation by Phase-Separated Activity-Enhancing Sequestration of the Viral Protease during Maturation

Sébastien Lyonnais , S. Kashif Sadiq , Cristina Lorca-Oró , Laure Dufau , Sara Nieto-Marquez , et al.
Viruses, 2021, 13 (11), pp.2312. ⟨10.3390/v13112312⟩
Article dans une revue hal-03449191v1
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Post-Translational Modifications of Retroviral HIV-1 Gag Precursors: An Overview of Their Biological Role

Charlotte Bussienne , Roland Marquet , Jean-Christophe Paillart , Serena Bernacchi
International Journal of Molecular Sciences, 2021, 22 (6), pp.2871. ⟨10.3390/ijms22062871⟩
Article dans une revue hal-03178636v1
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Degradation-Independent Inhibition of APOBEC3G by the HIV-1 Vif Protein

Benjamin Stupfler , Cédric Verriez , Sarah Gallois-Montbrun , Roland Marquet , Jean-Christophe Paillart
Viruses, 2021, 13 (4), pp.617. ⟨10.3390/v13040617⟩
Article dans une revue hal-03194958v1

In Search of New Inhibitors of HIV-1 Replication: Synthesis and Study of 1-(2'-Deoxy-beta-D-Ribofuranosyl)-1,2,4-Triazole-3-Carboxamide as a Selective Viral Mutagenic Agent.

V. Vivet-Boudou , J.-C. Paillart , A. Burger , Roland Marquet
Nucleosides, Nucleotides and Nucleic Acids, 2007, 26 (6), pp.743-6. ⟨10.1080/15257770701490902⟩
Article dans une revue hal-00200886v1

Targeting the dimerization initiation site of HIV-1 RNA with aminoglycosides: from crystal to cell.

E. Ennifar , J.C. Paillart , A. Bodlenner , P. Walter , J.M. Weibel , et al.
Nucleic Acids Research, 2006, 34, pp.2328-39
Article dans une revue hal-00094052v1

Tumultuous relationship between the human immunodeficiency virus type 1 viral infectivity factor (Vif) and the human APOBEC-3G and APOBEC-3F restriction factors.

Simon Henriet , Gaëlle Mercenne , Serena Bernacchi , Jean-Christophe Paillart , Roland Marquet
Microbiology and Molecular Biology Reviews, 2009, 73 (2), pp.211-32. ⟨10.1128/MMBR.00040-08⟩
Article dans une revue hal-00442900v1

APOBEC3G impairs the multimerization of the HIV-1 Vif protein in living cells

J. Batisse , S.X. Guerrero , S. Bernacchi , Laura Richert , J. Godet , et al.
Journal of Virology, 2013, 87 (11), pp.6492-6506. ⟨10.1128/JVI.03494-12⟩
Article dans une revue hal-00841235v1
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The HIV-1 ribonucleoprotein dynamically regulates its condensate behavior and drives acceleration of protease activity through membrane-less granular phase-separation

Sébastien Lyonnais , S Kashif Sadiq , Cristina Lorca-Oro , Laure Dufau , Sara Nieto-Marquez , et al.
2019
Pré-publication, Document de travail hal-02349017v1
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APOBEC3s: history of an antiviral and mutagenic protein family

Cédric Verriez , Roland Marquet , Jean-Christophe Paillart , Benjamin Stupfler
Virologie, 2020, 24 (6), pp.381-418. ⟨10.1684/vir.2020.0870⟩
Article dans une revue hal-03199783v1
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The DEAD box RNA helicase DDX42 is an intrinsic inhibitor of positive‐strand RNA viruses

Boris Bonaventure , Antoine Rebendenne , Ana Luiza Chaves Valadão , Mary Arnaud‐arnould , Ségolène Gracias , et al.
EMBO Reports, 2022, ⟨10.15252/embr.202154061⟩
Article dans une revue hal-03799508v1
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Advances in the structural understanding of Vif proteins.

Pierre Barraud , Jean-Christophe Paillart , Roland Marquet , Carine Tisné
Current HIV Research, 2008, 6 (2), pp.91-9
Article dans une revue hal-00381991v1
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Characterization of the interaction between the HIV-1 Gag structural polyprotein and the cellular ribosomal protein L7 and its implication in viral nucleic acid remodeling

Hala El Mekdad , Emmanuel Boutant , Hassan Karnib , Marina Elizabeth Biedma , Kamal Kant Sharma , et al.
Retrovirology, 2016, 13 (1), pp.54. ⟨10.1186/s12977-016-0287-4⟩
Article dans une revue inserm-02154958v1

Synthesis of a neamine dimer targeting the dimerization initiation site of HIV-1 RNA.

Anne Bodlenner , Aurélien Alix , Jean-Marc Weibel , Patrick Pale , Eric Ennifar , et al.
Organic Letters, 2007, 9 (22), pp.4415-8. ⟨10.1021/ol701760k⟩
Article dans une revue hal-00199249v1

5-Modified-2'-dU and 2'-dC as mutagenic anti HIV-1 proliferation agents: synthesis and activity.

Yazan El Safadi , Jean-Christophe Paillart , Géraldine Laumond , Anne-Marie Aubertin , Alain Burger , et al.
Journal of Medicinal Chemistry, 2010, 53 (4), pp.1534-45. ⟨10.1021/jm901758f⟩
Article dans une revue hal-00530476v1
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In cell mutational interference mapping experiment (in cell MIME) identifies the 5′ polyadenylation signal as a dual regulator of HIV-1 genomic RNA production and packaging

Redmond P Smyth , Maureen R Smith , Anne-Caroline Jousset , Laurence Despons , Géraldine Laumond , et al.
Nucleic Acids Research, 2018, 46 (9), pp.e57-e57. ⟨10.1093/nar/gky152⟩
Article dans une revue hal-02141231v1

A structure-based approach for targeting the HIV-1 genomic RNA dimerization initiation site.

Eric Ennifar , Jean-Christophe Paillart , Serena Bernacchi , Philippe Walter , Patrick Pale , et al.
Biochimie, 2007, 89 (10), pp.1195-203. ⟨10.1016/j.biochi.2007.03.003⟩
Article dans une revue istex hal-00199662v1

The C-terminal p6 domain of the HIV-1 Pr55 Gag precursor is required for specific binding to the genomic RNA

Noé Dubois , Keith Khoo , Shannon Ghossein , Tanja Seissler , Philippe Wolff , et al.
RNA Biology, 2018, 15 (7), pp.923-936. ⟨10.1080/15476286.2018.1481696⟩
Article dans une revue hal-02119045v1

Extensive uORF translation from HIV-1 transcripts conditions DDX3 dependency for expression of main ORFs and elicits specific T cell immune responses in infected individuals

Emmanuel Labaronne , Didier Décimo , Lisa Bertrand , Laura Guiguettaz , Thibault J.M. Sohier , et al.
2022
Pré-publication, Document de travail hal-03855362v1

Vif is a RNA chaperone that could temporally regulate RNA dimerization and the early steps of HIV-1 reverse transcription.

S. Henriet , L. Sinck , G. Bec , R. J. Gorelick , R. Marquet , et al.
Nucleic Acids Research, 2007, epub ahead of print. ⟨10.1093/nar/gkm542⟩
Article dans une revue hal-00167555v1
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A supramolecular assembly formed by influenza A virus genomic RNA segments.

Emilie Fournier , Vincent Moules , Boris Essere , Jean-Christophe Paillart , Jean-Daniel Sirbat , et al.
Nucleic Acids Research, 2012, 40 (5), pp.2197-209. ⟨10.1093/nar/gkr985⟩
Article dans une revue hal-00750133v1

Structural and Functional Motifs in Influenza Virus RNAs

Damien Ferhadian , Maud Contrant , Anne Printz-Schweigert , Redmond Smyth , Jean-Christophe Paillart , et al.
Frontiers in Microbiology, 2018, 9, ⟨10.3389/fmicb.2018.00559⟩
Article dans une revue hal-02118745v1

Translational regulation of APOBEC3G mRNA by Vif requires its 5′UTR and contributes to restoring HIV-1 infectivity

Santiago Guerrero , Camille Libre , Julien Batisse , Gaëlle Mercenne , Delphine Richer , et al.
Scientific Reports, 2016, 6 (1), ⟨10.1038/srep39507⟩
Article dans une revue hal-02294208v1

CTIP2 is a negative regulator of P-TEFb

Thomas Cherrier , Valentin Le Douce , Sebastian Eilebrecht , Raphael Riclet , Celine Marban , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2013, 110 (31), pp.12655-12660. ⟨10.1073/pnas.1220136110⟩
Article dans une revue hal-01544149v1
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A conserved uORF impacts APOBEC3G translation and is essential for translational inhibition by the HIV-1 Vif protein

Camille Libre , Tanja Seissler , Santiago Guerrero , Julien Batisse , Cédric Verriez , et al.
2021
Pré-publication, Document de travail hal-03369138v1