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Journal articles21 documents

  • Mattia Migliore, Andrea Bonvicini, Vincent Tognetti, Laure Guilhaudis, Marc Baaden, et al.. Characterization of β-turns by electronic circular dichroism spectroscopy: A coupled molecular dynamics and time-dependent density functional theory computational study. Physical Chemistry Chemical Physics, Royal Society of Chemistry, 2020, 22 (3), pp.1611-1623. ⟨10.1039/C9CP05776E⟩. ⟨hal-02397135⟩
  • Nathan Téné, Elsa Bonnafé, Fanny Berger, Aline Rifflet, Laure Guilhaudis, et al.. Biochemical and biophysical combined study of bicarinalin, an ant venom antimicrobial peptide. Peptides, Elsevier, 2016, 79, pp.103-113. ⟨10.1016/j.peptides.2016.04.001⟩. ⟨hal-01974252⟩
  • Jennifer Lagoutte-Renosi, Isabelle Ségalas-Milazzo, Marie Crahes, Florian Renosi, Laurence Menu-Bouaouiche, et al.. Lethal Neonatal Progression of Fetal Cardiomegaly Associated to ACAD9 Deficiency. Journal of Inherited Metabolic Disease, Springer Verlag, 2016, 28, pp.1-10. ⟨10.1007/8904_2015_499⟩. ⟨hal-02046219⟩
  • Romain Trouillard, Marie Hubert-Roux, Vincent Tognetti, Laure Guilhaudis, Carole Plasson, et al.. Determination of Multimodal Isotopic Distributions: The Case of a (15)N Labeled Protein Produced into Hairy Roots.. Analytical Chemistry, American Chemical Society, 2015, 87 (12), pp.5938-5946. ⟨10.1021/acs.analchem.5b01558⟩. ⟨hal-01186525⟩
  • Cindy Neveu, Fabienne Dulin, Benjamin Lefranc, Ludovic Galas, Colas Calbrix, et al.. Molecular basis of agonist docking in a human GPR103 homology model by site-directed mutagenesis and structure-activity relationship studies. British Journal of Pharmacology, Wiley, 2014, 171 (19), pp.4425-4439. ⟨10.1111/bph.12808⟩. ⟨hal-01973604⟩
  • Camille Pierry, Samuel Couve-Bonnaire, Laure Guilhaudis, Cindy Neveu, Amélie Marotte, et al.. Fluorinated pseudopeptide analogues of the neuropeptide 26RFa: synthesis, biological, and structural studies.. ChemBioChem, Wiley-VCH Verlag, 2013, 14 (13), pp.1620-1633. ⟨10.1002/cbic.201300325⟩. ⟨hal-01939216⟩
  • Cindy Neveu, Benjamin Lefranc, Olivier Tasseau, Jean-Claude Do-Rego, Adèle Bourmaud, et al.. Rational design of a low molecular weight, stable, potent, and long-lasting GPR103 aza-β3-pseudopeptide agonist. Journal of Medicinal Chemistry, American Chemical Society, 2012, 55 (17), pp.7516-7524. ⟨10.1021/jm300507d⟩. ⟨hal-01939210⟩
  • Ludovic Carlier, Joël Couprie, Albane Le Maire, Laure Guilhaudis, Isabelle Milazzo-Segalas, et al.. Solution structure of the region 51-160 of human KIN17 reveals an atypical winged helix domain. Protein Science, Wiley, 2009, 16 (12), pp.2750 - 2755. ⟨hal-00425483⟩
  • Steve Bourgault, David Vaudry, Isabelle Ségalas-Milazzo, Laure Guilhaudis, Alain Couvineau, et al.. Molecular and conformational determinants of pituitary adenylate cyclase-activating polypeptide (PACAP) for activation of the PAC1 receptor.. Journal of Medicinal Chemistry, American Chemical Society, 2009, 52 (10), pp.3308-3316. ⟨10.1021/jm900291j⟩. ⟨pasteur-00819957⟩
  • Ester Gutiérrez-Pascual, Jérôme Leprince, Antonio Martínez-Fuentes, Isabelle Ségalas-Milazzo, Rafael Pineda, et al.. In Vivo and in Vitro Structure-Activity Relationships and Structural Conformation of Kisspeptin-10-Related Peptides. Molecular Pharmacology, American Society for Pharmacology and Experimental Therapeutics, 2009, 76 (1), pp.58-67. ⟨10.1124/mol.108.053751⟩. ⟨hal-01962751⟩
  • Jérôme Leprince, David Chatenet, Christophe Dubessy, Alain Fournier, Bruno Pfeiffer, et al.. Structure–activity relationships of urotensin II and URP. Peptides, Elsevier, 2008, 29 (5), pp.658-673. ⟨10.1016/j.peptides.2007.08.014⟩. ⟨hal-01972605⟩
  • Stéphane Boivin, Isabelle Ségalas-Milazzo, Laure Guilhaudis, Hassan Oulyadi, Alain Fournier, et al.. Solution structure of urotensin-II receptor extracellular loop III and characterization of its interaction with urotensin-II. Peptides, Elsevier, 2008, 29 (5), pp.700-710. ⟨10.1016/j.peptides.2008.02.024⟩. ⟨hal-02352152⟩
  • Steve Bourgault, David Vaudry, Laure Guilhaudis, Emilie Raoult, Alain Couvineau, et al.. Biological and structural analysis of truncated analogs of PACAP27.. Journal of Molecular Neuroscience, Humana Press, 2008, 36 (1-3), pp.260-269. ⟨10.1007/s12031-008-9081-7⟩. ⟨pasteur-00819989⟩
  • Stéphane Boivin, Laure Guilhaudis, Isabelle Milazzo, Hassan Oulyadi, Daniel Davoust, et al.. Characterization of urotensin-II receptor structural domains involved in the recognition of U-II, URP, and urantide.. Biochemistry, American Chemical Society, 2006, 45 (19), pp.5993-6002. ⟨10.1021/bi060190b⟩. ⟨pasteur-00820020⟩
  • Séverine Zirah, Sergey A Kozin, Alexey K Mazur, Alain Blond, Michel Cheminant, et al.. Structural changes of region 1-16 of the Alzheimer disease amyloid beta-peptide upon zinc binding and in vitro aging.. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2006, 281 (4), pp.2151-61. ⟨10.1074/jbc.M504454200⟩. ⟨hal-00145835⟩
  • Ludovic Carlier, Albane Le Maire, Sandrine Braud, Cédric Masson, Muriel Gondry, et al.. NMR Assignment of Region 51–160 of Human KIN17, a DNA and RNA-binding Protein. Journal of Biomolecular NMR, Springer Verlag, 2006, 36 (S1), pp.29. ⟨10.1007/s10858-006-0013-y⟩. ⟨hal-02352045⟩
  • Nicolas Chartrel, Federica Bruzzone, Jérôme Leprince, Hélène Tollemer, Youssef Anouar, et al.. Structure and functions of the novel hypothalamic RFamide neuropeptides R-RFa and 26RFa in vertebrates. Peptides, Elsevier, 2006, 27 (5), pp.1110-1120. ⟨10.1016/j.peptides.2005.06.035⟩. ⟨hal-01960808⟩
  • Romain Thuau, Laure Guilhaudis, Isabelle Ségalas-Milazzo, Nicolas Chartrel, Hassan Oulyadi, et al.. Structural studies on 26RFa, a novel human RFamide-related peptide with orexigenic activity. Peptides, Elsevier, 2005, 26 (5), pp.779-789. ⟨10.1016/j.peptides.2005.01.006⟩. ⟨hal-01974257⟩
  • David Chatenet, Christophe Dubessy, Jérôme Leprince, Cédric Boularan, Ludovic Carlier, et al.. Structure–activity relationships and structural conformation of a novel urotensin II-related peptide. Peptides, Elsevier, 2004, 25 (10), pp.1819-1830. ⟨10.1016/j.peptides.2004.04.019⟩. ⟨hal-01960815⟩
  • Alain Blond, Michel Cheminant, Delphine Destoumieux-Garzón, Isabelle Ségalas-Milazzo, Jean Peduzzi, et al.. Thermolysin-linearized microcin J25 retains the structured core of the native macrocyclic peptide and displays antimicrobial activity.. European Journal of Biochemistry, Wiley, 2002, 269 (24), pp.6212-22. ⟨hal-00013189⟩
  • Alain Blond, Michel Cheminant, Isabelle Ségalas-Milazzo, Jean Péduzzi, Michel Barthélémy, et al.. Solution structure of microcin J25, the single macrocyclic antimicrobial peptide from Escherichia coli.. European Journal of Biochemistry, Wiley, 2001, 268 (7), pp.2124-2133. ⟨10.1046/j.1432-1327.2001.02090.x⟩. ⟨hal-00086378⟩

Conference papers18 documents

  • Laure Guilhaudis, Gaël Coadou, Muriel Sebban, Lina Truong, Isabelle Ségalas-Milazzo, et al.. Liquid state NMR applied to enzyme/substrate/inhibitor. Polymers for sustainable global development (POLY-CHAR, 2019), May 2019, Katmandou, Nepal. ⟨hal-02542279⟩
  • Mattia Migliore, Laure Guilhaudis, Benjamin Lefranc, Jérôme Leprince, Hassan Oulyadi, et al.. New insight in the structural characterization of turns in peptides: determination of NMR discriminatory parameters. Naples workshop on bioactive peptides (16, 2018), Jun 2018, Naples, Italy. ⟨hal-02381233⟩
  • Najjar Riham, Laure Guilhaudis, Nicolas Perzo, Hélène Castel, Isabelle Ségalas-Milazzo. Conformational studies of urotensinergic peptides using NMR and molecular modelling, in DPC micelles. Congrès du Groupe français des peptides et des protéines (GFPP, 20, 2017), Mar 2017, Arcachon, France. ⟨hal-02381245⟩
  • Amélie Marotte, Isabelle Buchet, Laure Guilhaudis, Benjamin Lefranc, Cindy Neveu, et al.. Investigating the conformational determinants of the activity of 26RFa: an orexigenic neuropeptide. Naples workshop on bioactive peptides (15, 2016), Jun 2016, Naples, Italy. ⟨hal-02380461⟩
  • Romain Trouillard, Marie Hubert-Roux, Vincent Tognetti, Laure Guilhaudis, Carole Plasson, et al.. Production of uniformly 15N/13C labeled glycosylated proteins by hairy roots in view to NMR structural studies. Congrès du Groupe français des peptides et des protéines (GFPP, 19, 2015), May 2015, Port-Bail, France. ⟨hal-02543922⟩
  • Romain Trouillard, Marie Hubert-Roux, Vincent Tognetti, Laure Guilhaudis, Carole Plasson, et al.. Production of uniformly 15N/13C labeled glycosylated proteins by hairy roots in view to NMR structural studies. Advanced Isotopic Labelling Methods for integrated structural biology (AILM, 2015), Feb 2015, Grenoble, France. ⟨hal-02378500⟩
  • Jane Eilen Joubert, Laurence Desrues, Nicolas Perzo, B Taddese, Céline Lecointre, et al.. Impact of a key ancestral deletion in chemokine and vasoactive peptide receptors on G protein couplings and chemotaxis. GPCRs: Beyond Structure Towards Therapy, Sep 2015, Prato, Italy. ⟨hal-02296948⟩
  • Romain Trouillard, Marie Hubert, Laure Guilhaudis, Laurence Menu-Bouaouiche, Carole Plasson, et al.. Production de protéines marquées 15N ou 15N/13C dans un système d’expression racinaire et analyse de l’incorporation du marquage par spectrométrie de masse. Journée de l’Institut de recherche et d'innovation biomédicale (3, 2014), Jun 2014, Caugé, France. ⟨hal-02113295⟩
  • Jane Eilen Joubert, Laurence Desrues, Nicolas Perzo, Céline Lecointre, A Arrichiello, et al.. Impact of a key mutation of a proline in chemokine and vasoactive peptide receptors: A structural determinant in chemotaxis?. GDR-GPCR (3, 2014), Oct 2014, Montpellier, France. ⟨hal-02299458⟩
  • Hélène Castel, Jane Eilen Joubert, Céline Lecointre, A Arrichiello, Laurence Desrues, et al.. Key proline position in chemokine and vasoactive peptide receptors on chemotaxic behavior. International Symposium on Regulatory Peptides (REGPEP, 20, 2014), Sep 2014, Kyoto, Japan. ⟨hal-02299536⟩
  • Lucie Dubousset, Abdoul-Salam Koroney, Marie-Christine Kiefer-Meyer, Gaëlle Durambur, Laure Guilhaudis, et al.. Production dans des plantes transgéniques de protéines marquées 13C et 15N en vue d’une étude structurale par RMN. Journée scientifique de l'IFRMP23 (17, 2011), Jun 2011, Rouen, France. ⟨hal-02121347⟩
  • Laure Guilhaudis, Cindy Neveu, Olivier Le Marec, Olivier Tasseau, Benjamin Lefranc, et al.. Etude pharmacochimique du 26RFa : relations structure-activité d'une série d'Aza-B3-pseudopeptides. 14EME JOURNEE SCIENTIFIQUE DE L'IFRMP23, Jun 2008, EVREUX, France. ⟨hal-00361308⟩
  • Olivier Le Marec, Cindy Neveu, Olivier Tasseau, Laure Guilhaudis, Isabelle Ségalas-Milazzo, et al.. Activité biologique d'une série d'analogues pseudopeptidiques aza-Β3 du 26RFa, le ligand endogène du GPR103. 35ème Colloque de la Société de Neuroendocrinologie, Sep 2008, Strasbourg, France. ⟨hal-00361319⟩
  • A. Blond, M. Cheminant, I. Ségalas-Milazzo, D. Destoumieux-Garzón, C. Goulard, et al.. Three-Dimensional structure of a thermolysin-linearized microcin J25: Evidence for an essential role of the 11-16 loop in microcin J25 structure and antimicrobial activity. Peptides 2002, 2002, France. pp.866-867. ⟨hal-00013606⟩
  • A. Blond, M. Cheminant, I. Ségalas-Milazzo, D. Destoumieux-Garzón, C. Goulard, et al.. Three-Dimensional structure of a thermolysin-linearized microcin J25: Evidence for an essential role of the 11-16 loop in microcin J25 structure and antimicrobial activity. 27th European Peptide Symposium, Sep 2002, Sorrento, Italy. ⟨hal-00013628⟩
  • G. Leclerc, M. Cheminant, I. Segalas, A. Blond, J. Peduzzi, et al.. The NMR three-dimensional structure of the peptaibol antibiotic longibrachin LGA I. Peptides 2000, Proceedings 26th European Peptide Symposium, Sep 2000, Montpellier, France. ⟨hal-00087884⟩
  • I. Segalas, Y. Prigent, D. Davoust, Bernard Bodo, S. Rebuffat. NMR-Based solution structure of the 14-residue peptaibol, harzianin HC IX. 25th European Peptide Symposium, 2000, France. pp.382-383. ⟨hal-00087888⟩
  • Alain Blond, M. Cheminant, Isabelle Ségalas-Milazzo, Jean Peduzzi, M. Barthélémy, et al.. The compact three-dimensional structure of the 21-residue cyclic antibiotic peptide, microcin J25. Peptides 2000, Proceedings 26h European Peptide Symposium, 2000, Montpellier, France. ⟨hal-00087869⟩

Poster communications18 documents

  • Mattia Migliore, Laure Guilhaudis, Benjamin Lefranc, Jérôme Leprince, Hassan Oulyadi, et al.. New insights in structural characterization of turns in peptides: in silico determination of new NMR discriminatory parameters. Journée de l’Ecole doctorale normande de chimie (JEDNC, 2019), Jul 2019, Caen, France. ⟨hal-02542528⟩
  • Mattia Migliore, Laure Guilhaudis, Benjamin Lefranc, Jérôme Leprince, Hassan Oulyadi, et al.. Structural characterization of turns in proteins and peptides: new NMR discriminatory parameters by molecular modelling. Congrès du Groupe français des peptides et des protéines (GFPP, 21, 2019), May 2019, Amboise, France. ⟨hal-02542520⟩
  • Andrea Bonvicini, Mattia Migliore, Isabelle Ségalas-Milazzo, Vincent Tognetti, Laurent Joubert, et al.. Characterization of beta-turns by ECD spectroscopy. A coupled molecular dynamics and TD-DFT computational study. Conference on Chiroptical Spectroscopy - CD 2019 (17, 2019), Jun 2019, Pise, Italy. ⟨hal-02542310⟩
  • Riham Najjar, Laure Guilhaudis, Maxime Burnacci, Hassan Oulyadi, Hélène Castel, et al.. Comparative structural analyses of urotensinergic peptides by CD spectroscopy, solution NMR and molecular modelling. European Magnetic Resonance Meeting (EUROMAR, 14, 2018), Jul 2018, Nantes, France. ⟨hal-02452551⟩
  • Mattia Migliore, Laure Guilhaudis, Benjamin Lefranc, Jérôme Leprince, Hassan Oulyadi, et al.. New insights in structural characterization of turns in peptides: in silico determination of new NMR discriminatory parameters. Journée de l’Ecole doctorale normande de chimie (JEDNC, 2018), Jun 2018, Le Havre, France. ⟨hal-02542538⟩
  • Mattia Migliore, Laure Guilhaudis, Benjamin Lefranc, Jérôme Leprince, Isabelle Ségalas-Milazzo. Structural characterization of turns in bioactive peptides - Determination of NMR discriminatory parameters. Journée de l’Ecole doctorale normande de chimie (JEDNC, 2017), Jun 2017, Mont-Saint-Aignan, France. ⟨hal-02542501⟩
  • Laurence Desrues, Eilen Joubert Jane, Nicolas Perzo, Laure Guilhaudis, Isabelle Milazzo, et al.. Proline in 2.58 of chemokine and vasoactive peptide G-protein coupled receptors: A structural determinant in chemotaxis?. Annual Meeting of the LARC-Neuroscience network (21, 2017), Oct 2017, Lille, France. ⟨hal-02341500⟩
  • Laurence Desrues, Eilen Joubert Jane, Pierre-Mickaël Coly, Alexandre Mutel, Nicolas. Perzo, et al.. A structural determinant in TM2 of chemokine and vasoactive peptide GPCRs plays a key role in cell chemotactic migration. Annual Meeting of GDR3545 (6, 2017), Nov 2017, Paris, France. ⟨hal-02341487⟩
  • R. Najjar, Laure Guilhaudis, Nicolas Perzo, Hélène Castel, Isabelle Ségalas-Milazzo. Solution NMR studies of urotensinergic peptides in DPC micelles, a membrane mimetic medium. International Regulatory Peptide Society Congress, Jul 2016, Rouen, France. ⟨hal-02345192⟩
  • R. Najjar, Laure Guilhaudis, Nicolas Perzo, Hélène Castel, Isabelle Ségalas-Milazzo. Structural analyses of urotensinergic peptides by NMR spectroscopy and molecular modelling. Journée normande de recherche biomédicale IRIB-ICORE (1, 2016), Sep 2016, Rouen, France. ⟨hal-02345177⟩
  • Hélène Castel, Jane Eileen Joubert, Laurence Desrues, Nicolas Perzo, Céline Lecointre, et al.. Impact of a key ancestral deletion in chemokine and vasoactive peptide receptors on chemotaxis. Colloque de la Société de neuroendocrinologie (41, 2016), Oct 2016, Corte, France. ⟨hal-02349071⟩
  • Samuel Couve-Bonnaire, Camille Pierry, Emilie Villiers, Guillaume Dutheuil, Laure Guilhaudis, et al.. Asymmetric synthesis of fluoropseudopeptides towards constrained prolines and analogue of neuropeptide 26 RFa. Congrès du Groupe français des peptides et des protéines (GFPP, 19, 2015), May 2015, Port-Bail, France. ⟨hal-02543329⟩
  • Laure Guilhaudis, R. Najjar, Nicolas Perzo, Hélène Castel, Isabelle Ségalas-Milazzo. Comparative structural analyses of urotensinergic peptides by CD spectroscopy, NMR and Molecular Modelling. Congrès du Groupe français des peptides et des protéines (GFPP, 19, 2015), May 2015, Port-Bail, France. ⟨hal-02349922⟩
  • Riham Najjar, Laure Guilhaudis, Nicolas Perzo, Hélène Castel, Isabelle Ségalas-Milazzo. Comparative structural analyses of urotensinergic peptides by CD spectroscopy, NMR and Molecular Modelling. Journée Scientifique de l'’Institut de Recherche et d’Innovation Biomédicale (IRIB), Jun 2015, Rouen, France. ⟨hal-02543925⟩
  • Karima Alim, Laure Guilhaudis, Isabelle Ségalas-Milazzo, David Vaudry, Julien Chuquet, et al.. Demonstration of the occurrence of a non-transmembrane -helix in the extracellular loop 2 of GPR103. Congrès du Groupe français des peptides et des protéines (GFPP, 19, 2015), May 2015, Port-Bail, France. ⟨hal-02543930⟩
  • Eileen Joubert, Laurence Desrues, Nicolas Perzo, Céline Lecointre, Antoine Arrichiello, et al.. Impact of a key mutation of a proline in chemokine and vasoactive peptide receptors: A structural determinant in chemotaxis?. Journées de l’Ecole doctorale normande Biologie Intégrative, Santé, Environnement (EdN BISE, 18, 2015), Mar 2015, Mont-Saint-Aignan, France. ⟨hal-02349914⟩
  • Jane Eileen Joubert, Laurence Desrues, Nicolas Perzo, Céline Lecointre, Laure Guilhaudis, et al.. Impact of a key ancestral deletion in chemokine and vasoactive peptide receptors on chemotaxis. Colloque de la Société des neurosciences (12, 2015), May 2015, Montpellier, France. ⟨hal-02349910⟩
  • Romain Trouillard, Marie Hubert, Laure Guilhaudis, Laurence Menu-Bouaouiche, Carole Plasson, et al.. Production de protéines marquées 15N ou 15N/13C dans un système d’expression racinaire et analyse de l’incorporation du marquage par spectrométrie de masse. Journée de l’Institut de recherche et d’innovation biomédicale (2, 2013), Jun 2013, Rouen, France. ⟨hal-02115362⟩

Book sections1 document

Directions of work or proceedings4 documents

  • Amélie Marotte, Laure Guilhaudis, Ganesan S, Cindy Neveu, Benjamin Lefranc, et al.. Investigating the structural determinants of neuropeptide 26RFa required for the activation of the receptor GPR103. The European Peptides Society. European peptide symposium (EPS, 32, 2012), Sep 2012, Athènes, Greece. pp.534-535, 2012, Petides 2012. ⟨hal-01973017⟩
  • Olivier Le Marec, Cindy Neveu, Olivier Tasseau, Laure Guilhaudis, Isabelle Ségalas-Milazzo, et al.. Synthesis and biological activity of a series of aza-b3-pseudopeptides related to 26RFa, the endogenous ligand of GPR103. Peptides 2008, Proceedings of the 30th European Peptide Symposium, pp 524-525. 2009. ⟨hal-01962817⟩
  • Olivier Le Marec, Christophe Dubessy, Jean-Claude Do Rego, Olivier Nosjean, Valérie Audinot, et al.. Agonist and antagonist activities of peptides related to 26RFa, the last member of the RFamide peptide superfamily. Peptides 2006, Proceedings of the 29th European Peptide Symposium, pp 378-279. 2007. ⟨hal-01962812⟩
  • David Chatenet, Jérôme Leprince, Christophe Dubessy, Ludovic Carlier, Cedric Boularan, et al.. Structure-activity relationships and structural conformation of a novel urotensin II-related peptide. Peptides 2004. Proceedings of the 3rd International and 28th European Symposium, pp 804-805. 2005. ⟨hal-01960838⟩