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NMR spectroscopy of the main protease of SARS‐CoV‐2 and fragment‐based screening identify three protein hotspots and an antiviral fragment
François-Xavier Cantrelle
,
Emmanuelle Boll
,
Lucile Brier
,
Danai Moschidi
,
Sandrine Belouzard
,
et al.
Article dans une revue
hal-03363607v1
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Backbone chemical shift assignments of human 14-3-3σ
João Filipe Neves
,
Isabelle Landrieu
,
Hamida Merzougui
,
Emmanuelle Boll
,
Xavier Hanoulle
,
et al.
Article dans une revue
hal-02107858v1
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Systematic identification of tubulin interacting fragments of the microtubule-associated protein TAU leads to a highly efficient promoter of microtubule assembly.
Caroline Fauquant
,
Virginie Redeker
,
Isabelle Landrieu
,
Jean-Michel Wieruzseski
,
Dries Verdegem
,
et al.
Article dans une revue
hal-00618268v1
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Structural basis for the non-immunosuppressive character of the cyclosporin A analogue Debio 025.
Isabelle Landrieu
,
Xavier Hanoulle
,
Fanny Bonachera
,
Arnaud Hamel
,
Nathalie Sibille
,
et al.
Article dans une revue
hal-00508817v1
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Domain 3 of NS5A protein from the hepatitis C virus has intrinsic {alpha}-helical propensity and is a substrate of Cyclophilin A.
Dries Verdegem
,
Aurelie Badillo
,
Jean-Michel Wieruszeski
,
Isabelle Landrieu
,
Arnaud Leroy
,
et al.
Article dans une revue
hal-00586923v1
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Fragment-based Differential Targeting of PPI Stabilizer Interfaces
Xavier Guillory
,
Madita Wolter
,
Seppe Leysen
,
João Filipe Neves
,
Ave Kuusk
,
et al.
Article dans une revue
hal-02990641v1
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The FK506-binding protein FKBP52 in vitro induces aggregation of truncated Tau forms with prion-like behavior.
Julien Giustiniani
,
Kevin Guillemeau
,
Omar Dounane
,
Elodie Sardin
,
Isabelle Huvent
,
et al.
FASEB Journal, 2015, Epub ahead of print
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hal-01145979v1
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Towards understanding the phosphorylation code of tau.
Guy Lippens
,
Laziza Amniai
,
Jean-Michel Wieruszeski
,
Alain Sillen
,
Arnaud Leroy
,
et al.
Article dans une revue
hal-00765867v1
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A small CDC25 dual-specificity tyrosine-phosphatase isoform in Arabidopsis thaliana
Isabelle Landrieu
,
Marco da Costa
,
Lieven de Veylder
,
Frédérique Dewitte
,
Klaas Vandepoele
,
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2004, 101 (36), pp.13380-13385. ⟨10.1073/pnas.0405248101⟩
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hal-02681405v1
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NMR spectroscopy of the neuronal tau protein: normal function and implication in Alzheimer's disease.
Isabelle Landrieu
,
Arnaud Leroy
,
Caroline Smet-Nocca
,
Isabelle Huvent
,
Laziza Amniai
,
et al.
Article dans une revue
hal-00586933v1
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Identification of a Plasmodium falciparum inhibitor-2 motif involved in the binding and regulation activity of protein phosphatase type 1.
Aline Fréville
,
Géraldine Tellier
,
Audrey Vandomme
,
Christine Pierrot
,
Jérôme Vicogne
,
et al.
Article dans une revue
hal-01077866v1
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Cell signaling, post-translational protein modifications and NMR spectroscopy.
Francois-Xavier Theillet
,
Caroline Smet-Nocca
,
Stamatios Liokatis
,
Rossukon Thongwichian
,
Jonas Kosten
,
et al.
Article dans une revue
hal-00765863v1
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Regulation of the interaction between the neuronal BIN1 isoform 1 and Tau proteins - role of the SH3 domain
Idir Malki
,
François-Xavier Cantrelle
,
Yoann Sottejeau
,
Guy Lippens
,
Jean-Charles Lambert
,
et al.
Article dans une revue
hal-01620146v1
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ELISE NMR: Experimental liquid sealing of NMR samples.
Jean-Michel Wieruszeski
,
Isabelle Landrieu
,
Xavier Hanoulle
,
Guy Lippens
Journal of Magnetic Resonance, 2006, Epub ahead of print, Epub ahead of print
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hal-00085597v1
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Structural analysis of Escherichia coli OpgG, a protein required for the biosynthesis of osmoregulated periplasmic glucans.
Xavier Hanoulle
,
Eglantine Rollet
,
Bernard Clantin
,
Isabelle Landrieu
,
Carmen Ödberg-Ferragut
,
et al.
Journal of Molecular Biology, 2004, 342, pp.195-205
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hal-00020845v1
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Magnetic resonance investigation of conformational responses of tau protein to specific phosphorylation
Alessia Lasorsa
,
Hamida Merzougui
,
François-Xavier Cantrelle
,
Giuseppe Sicoli
,
Elian Dupré
,
et al.
Biophysical Chemistry, 2024, Part of special issue Biophysical, Biochemical, and Cellular Events Underlying Proteinopathies Edited by Carmelo La Rosa, Danilo Milardi, Magdalena Ivanova, Andisheh Abedini, Lucie Khemtemourian, Ayyalusamy Ramamoorthy, 305 (107155), pp.107155. ⟨10.1016/j.bpc.2023.107155⟩
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hal-04440623v1
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Structural characterization by nuclear magnetic resonance of the impact of phosphorylation in the proline-rich region of the disordered Tau protein.
Nathalie Sibille
,
Isabelle Huvent
,
Caroline Fauquant
,
Dries Verdegem
,
Laziza Amniai
,
et al.
Article dans une revue
istex
hal-00713027v1
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Recombinant production of the p10CKS1At protein from Arabidopsis thaliana and 13C and 15N double-isotopic enrichment for NMR studies
I. Landrieu
,
P. Casteels
,
B. Odaert
,
Lieven de Veylder
,
D. Portetelle
,
et al.
Protein Expression and Purification, 1999, 16, pp.144-151
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hal-02686867v1
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Phosphorylation in intrinsically disordered regions regulates the activity of Neurogenin2.
Gary S Mcdowell
,
Christopher J Hindley
,
Guy Lippens
,
Isabelle Landrieu
,
Anna Philpott
BMC Biochemistry, 2014, pp.24
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hal-01081937v1
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Identification of the Tau phosphorylation pattern that drives its aggregation
Clement Despres
,
Cillian Byrne
,
Haoling Qi
,
François-Xavier Cantrelle
,
Isabelle Huvent
,
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (34), pp.9080 - 9085. ⟨10.1073/pnas.1708448114⟩
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hal-01620128v1
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A β-Turn Motif in the Steroid Hormone Receptor’s Ligand-Binding Domains Interacts with the Peptidyl-prolyl Isomerase (PPIase) Catalytic Site of the Immunophilin FKBP52
Cillian Byrne
,
Morkos A. Henen
,
Mathilde Belnou
,
François-Xavier Cantrelle
,
Amina Kamah
,
et al.
Article dans une revue
hal-01389826v1
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Tau aggregation in Alzheimer's disease : what role for phosphorylation ?
Guy Lippens
,
Alain Sillen
,
Isabelle Landrieu
,
Laziza Amniai
,
Nathalie Sibille
,
et al.
Prion, 2007, 1 (1), pp.21-25
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hal-00161158v1
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Major Differences between the Self-Assembly and Seeding Behavior of Heparin-Induced and in Vitro Phosphorylated Tau and Their Modulation by Potential Inhibitors
Clément Despres
,
Jing Di
,
François-Xavier Cantrelle
,
Zizheng Li
,
Isabelle Huvent
,
et al.
Article dans une revue
hal-02317189v1
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Stabilizer-Guided Inhibition of Protein-Protein Interactions
Lech-Gustav Milroy
,
Maria Bartel
,
Morkos A. Henen
,
Seppe Leysen
,
Joris M. C. Adriaans
,
et al.
Article dans une revue
istex
hal-01389833v1
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Deciphering the Structure and Formation of Amyloids in Neurodegenerative Diseases With Chemical Biology Tools
Isabelle Landrieu
,
Elian Dupré
,
Davy Sinnaeve
,
Léa El Hajjar
,
Caroline Smet-Nocca
Article dans une revue
hal-03841022v1
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1H, 15N and 13C assignments of the N-terminal domain of the Mediator complex subunit MED26
Riccardo Peruzzini
,
Zoé Lens
,
Alexis Verger
,
Frédérique Dewitte
,
Elisabeth Ferreira
,
et al.
Article dans une revue
hal-01389830v1
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NMR reveals the intrinsically disordered domain 2 of NS5A protein as an allosteric regulator of the hepatitis C virus RNA polymerase NS5B
Luiza Bessa
,
Hélène Launay
,
Marie Dujardin
,
Xavier Cantrelle
,
Guy Lippens
,
et al.
Article dans une revue
hal-01620117v1
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Microtubule and MAPs: thermodynamics of complex formation by AUC, ITC, fluorescence, and NMR.
François Devred
,
Pascale Barbier
,
Daniel Lafitte
,
Isabelle Landrieu
,
Guy Lippens
,
et al.
Article dans une revue
hal-00508818v1
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Design Of Drug-Like Protein-Protein Interaction Stabilizers Guided By Chelation-Controlled Bioactive Conformation Stabilization
Francesco Bosica
,
Sebastian Andrei
,
João Filipe Neves
,
Peter Brandt
,
Anders Gunnarsson
,
et al.
Article dans une revue
hal-02989288v1
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1H, 13C, and 15N chemical shift assignment of human PACSIN1/syndapin I SH3 domain in solution
Emmanuelle Boll
,
François-Xavier Cantrelle
,
Isabelle Landrieu
,
Matthieu Hirel
,
Davy Sinnaeve
,
et al.
Article dans une revue
hal-02537946v1
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