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Combining devs and semantic technologies for modeling the SARS-COV-2 replication machinery

Ali Ayadi , Claudia Frydman , Wissame Laddada , Lina Soualmia , Cecilia Zanni-Merk , et al.
annual modeling and simulation conference, Jul 2021, San Diego, United States
Communication dans un congrès hal-03614037v1

Crystallization and diffraction analysis of the SARS coronavirus nsp10-nsp16 complex.

Claire Debarnot , Isabelle Imbert , Francois Ferron , Laure Gluais , Isabelle Varlet , et al.
Acta crystallographica Section F : Structural biology communications [2014-..], 2011, 67 (Pt 3), pp.404-8. ⟨10.1107/S1744309111002867⟩
Article dans une revue hal-00751530v1

Understanding the Mechanism of the Broad-Spectrum Antiviral Activity of Favipiravir (T-705): Key Role of the F1 Motif of the Viral Polymerase

Rana Abdelnabi , Ana Theresa Silveira De Morais , Pieter Leyssen , Isabelle Imbert , Stéphanie Beaucourt , et al.
Journal of Virology, 2017, 91 (12), pp.e00487-17. ⟨10.1128/JVI.00487-17⟩
Article dans une revue pasteur-02545928v1
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Structure Prediction and Analysis of Hepatitis E Virus Non-Structural Proteins from the Replication and Transcription Machinery by AlphaFold2

Adeline Goulet , Christian Cambillau , Alain Roussel , Isabelle Imbert
Viruses, 2022, 14, ⟨10.3390/v14071537⟩
Article dans une revue hal-03856706v1

Coronavirus Nsp10, a critical co-factor for activation of multiple replicative enzymes

Mickaël Bouvet , Adrien Lugari , Clara C. Posthuma , Jessika C. Zevenhoven , Stéphanie Bernard , et al.
Journal of Biological Chemistry, 2014, 289 (37), pp.25783-25796. ⟨10.1074/jbc.M114.577353⟩
Article dans une revue hal-01910944v1

Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA

Francois Ferron , Lorenzo Subissi , Ana Theresa Silveira de Morais , Nhung Thi Tuyet Le , Marion Sevajol , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (2), pp.E162-E171. ⟨10.1073/pnas.1718806115⟩
Article dans une revue hal-02094607v1
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Replication of the coronavirus genome: A paradox among positive-strand RNA viruses

Emeline Grellet , India l'Hôte , Adeline Goulet , Isabelle Imbert
Journal of Biological Chemistry, 2022, 298, ⟨10.1016/j.jbc.2022.101923⟩
Article dans une revue hal-03856707v1

Combining DEVS simulation and ontological modeling for hierarchical analysis of the SARS-CoV-2 replication

Ali Ayadi , Claudia Frydman , Wissame Laddada , Isabelle Imbert , Cecilia Zanni-Merk , et al.
SIMULATION: Transactions of The Society for Modeling and Simulation International, 2023, ⟨10.1177/00375497231176085⟩
Article dans une revue hal-04137173v1
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The C-Terminal Domain of the Sudan Ebolavirus L Protein Is Essential for RNA Binding and Methylation

Coralie Valle , Baptiste Martin , Françoise Debart , Jean-Jacques Vasseur , Isabelle Imbert , et al.
Journal of Virology, 2020, 94 (12), pp.e00520-20. ⟨10.1128/JVI.00520-20⟩
Article dans une revue hal-02890587v1