Accéder directement au contenu

Isabelle Fournier

Professor Senior Member Institut Universitaire de France Vice President for Doctoral Research at University of Lille
79%
Libre accès
24
Documents
Affiliations actuelles
  • 1189276
Identifiants chercheurs
Contact

Présentation

Prof. Fournier is Distinguished Professor at University of Lille, and she holds a position as co-director of the PRISM Inserm U1192 Lab and as Vice President for Doctoral Research for the university. She is a bioanalytical chemist specialized in clinical mass spectrometry and proteomics. She started research working on fundamental of MALDI during her PhD at University Pierre & Marie Curie in Paris first and then, as a postdoctoral fellow within the group of Prof. Michael Karas in Frankfurt. In 2002, she established her own group at University of Lille where she started developing MALDI MS Imaging. She contributed to the field with several developments including strategies for imaging of FFPE tissues and proteins, and the development of tagged probes for specific imaging of mRNA and antigens. In 2009, she was hired as Full Professor and awarded a Junior position at Institut Universitaire de France. Since 2012, she got interested by the development of Spatially Resolved Proteomics in combination to MALDI MSI for applications in oncology. Over the past 5 years, she also worked on the development of in vivo MS for guided surgery and intraoperative analysis. She confounded the Imabiotech Company which provides services in MALDI MSI and recently CELEOS that will commercialize the SpiderMass technology. She was recently distinguished by the international distinguish award from MSACL and was awarded a senior position at Institut Universitaire de France in 2019.

Domaines de recherche

Chimie analytique Génomique, Transcriptomique et Protéomique [q-bio.GN] Imagerie

Compétences

mass spectrometry imaging proteomics spatial proteomics lipidomics health technology

Publications

"tristan-cardon"
Image document

Protocol to identify human subcellular alternative protein interactions using cross-linking mass spectrometry.

Diego-Fernando Garcia del Rio , Isabelle Fournier , Tristan Cardon , Michel Salzet
STAR Protocols, 2023, STAR Protocols, 4 (3), pp.102380. ⟨10.1016/j.xpro.2023.102380⟩
Article dans une revue hal-04400811v1

Heimdall, an alternative protein issued from a ncRNA related to kappa light chain variable region of immunoglobulins from astrocytes: a new player in neural proteome

Alice Capuz , Sylvain Osien , Tristan Cardon , Mélodie Anne Karnoub , Soulaimane Aboulouard
Cell Death and Disease, 2023, 14 (8), pp.526. ⟨10.1038/s41419-023-06037-y⟩
Article dans une revue hal-04476023v1

Correction: Heimdall, an alternative protein issued from a ncRNA related to kappa light chain variable region of immunoglobulins from astrocytes: a new player in neural proteome

Alice Capuz , Sylvain Osien , Tristan Cardon , Mélodie Anne Karnoub , Soulaimane Aboulouard
Cell Death and Disease, 2023, 14 (10), pp.677. ⟨10.1038/s41419-023-06143-x⟩
Article dans une revue hal-04278155v1

Heimdall, an alternative protein issued from a ncRNA related to kappa light chain variable region of immunoglobulins from astrocytes: a new player in neural proteome

Alice Capuz , Sylvain Osien , Tristan Cardon , Mélodie Anne Karnoub , Soulaimane Aboulouard
Cell Death and Disease, 2023, 14 (8), pp.526. ⟨10.1038/s41419-023-06037-y⟩
Article dans une revue hal-04528686v1
Image document

Fallopian tube lesions as potential precursors of early ovarian cancer: a comprehensive proteomic analysis.

Maxence Wisztorski , Soulaimane Aboulouard , Lucas Roussel , Marie Duhamel , Philippe Saudemont
Cell Death and Disease, 2023, Cell Death and Disease, 14, pp.644. ⟨10.1038/s41419-023-06165-5⟩
Article dans une revue hal-04400929v1
Image document

Employing non-targeted interactomics approach and subcellular fractionation to increase our understanding of the ghost proteome

Diego-Fernando Garcia del Rio , Tristan Cardon , S. Eyckerman , Isabelle Fournier , Amelie Bonnefond
iScience, 2023, Iscience, 26, pp.105943. ⟨10.1016/j.isci.2023.105943⟩
Article dans une revue hal-04401042v1
Image document

Spatial analysis of the glioblastoma proteome reveals specific molecular signatures and markers of survival.

Marie Duhamel , L. Drelich , Maxence Wisztorski , Soulaimane Aboulouard , Jean-Pascal Gimeno
Nature Communications, 2022, Nature Communications, 13, pp.6665. ⟨10.1038/s41467-022-34208-6⟩
Article dans une revue hal-04212126v1
Image document

Protein kinase c activation drives a differentiation program in an oligodendroglial precursor model through the modulation of specific biological networks

Marina Damato , Tristan Cardon , Maxence Wisztorski , Isabelle Fournier , Damiana Pieragostino
International Journal of Molecular Sciences, 2021, International Journal of Molecular Sciences, 22 (10), pp.5245. ⟨10.3390/ijms22105245⟩
Article dans une revue hal-03967287v1
Image document

In-depth proteomics analysis of sentinel lymph nodes from individuals with endometrial cancer

Soulaimane Aboulouard , Maxence Wisztorski , Marie Duhamel , Philippe Saudemont , Tristan Cardon
Cell Reports Medicine, 2021, Cell Reports Medicine, 2 (6), pp.100318. ⟨10.1016/j.xcrm.2021.100318⟩
Article dans une revue hal-04009565v1
Image document

Unveiling a ghost proteome in the glioblastoma non-coding rnas

Tristan Cardon , Isabelle Fournier , Michel Salzet
Frontiers in Cell and Developmental Biology, 2021, Frontiers in Cell and Developmental Biology, 9, pp.703583. ⟨10.3389/fcell.2021.703583⟩
Article dans une revue hal-04011459v1
Image document

Surfaceome proteomic of glioblastoma revealed potential targets for immunotherapy

Melanie Rose , Tristan Cardon , Soulaimane Aboulouard , Nawale Hajjaji , Firas Kobeissy
Frontiers in Immunology, 2021, Frontiers in Immunology, 12, pp.746168. ⟨10.3389/fimmu.2021.746168⟩
Article dans une revue hal-04009596v1

Neurotrauma investigation through spatial omics guided by mass spectrometry imaging: Target identification and clinical applications

Khalil Mallah , Kazem Zibara , Coline Kerbaj , Ali Eid , Nour Khoshman
Mass Spectrometry Reviews, 2021, 42 (1), pp.189-205. ⟨10.1002/mas.21719⟩
Article dans une revue hal-04443805v1

Shedding Light on the Ghost Proteome

Tristan Cardon , Isabelle Fournier , Michel Salzet
Trends in Biochemical Sciences, 2021, 46 (3), pp.239-250. ⟨10.1016/j.tibs.2020.10.003⟩
Article dans une revue hal-04446903v1
Image document

Sars-cov-2 interactome with human ghost proteome: a neglected world encompassing a wealth of biological data

Tristan Cardon , Isabelle Fournier , Michel Salzet
Microorganisms, 2020, Microorganisms, 8 (12), pp.2036. ⟨10.3390/microorganisms8122036⟩
Article dans une revue hal-03966962v1
Image document

Alternative proteins are functional regulators in cell reprogramming by PKA activation

Tristan Cardon , Julien Franck , Etienne Coyaud , Estelle Laurent , Marina Damato
Nucleic Acids Research, 2020, 48 (14), pp.7864-7882. ⟨10.1093/nar/gkaa277⟩
Article dans une revue inserm-02941812v1

Epigenetic Studies Revealed a Ghost Proteome in PC1/3 KD Macrophages under Antitumoral Resistance Induced by IL-10

Tristan Cardon , Bilgehan Ozcan , Soulaimane Aboulouard , Firas Kobeissy , Marie Duhamel
Article dans une revue hal-04445712v1
Image document

Reference and Ghost Proteins Identification in Rat C6 Glioma Extracellular Vesicles

Adriana-Natalia Murgoci , Tristan Cardon , Soulaimane Aboulouard , Marie Duhamel , Isabelle Fournier
iScience, 2020, 23 (5), pp.101045. ⟨10.1016/j.isci.2020.101045⟩
Article dans une revue inserm-02941792v1

Optimized Sample Preparation Workflow for Improved Identification of Ghost Proteins

Tristan Cardon , Flore Hervé , Vivian Delcourt , Xavier Roucou , Michel Salzet
Analytical Chemistry, 2019, 92 (1), pp.1122-1129. ⟨10.1021/acs.analchem.9b04188⟩
Article dans une revue inserm-02941813v1

Mapping Spatiotemporal Microproteomics Landscape in Experimental Model of Traumatic Brain Injury Unveils a link to Parkinson's Disease

Khalil Mallah , Jusal Quanico , Antonella Raffo-Romero , Tristan Cardon , Soulaimane Aboulouard
Molecular and Cellular Proteomics, 2019, 18 (8), pp.1669-1682. ⟨10.1074/mcp.RA119.001604⟩
Article dans une revue inserm-02941592v1

Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging of Lipids in Experimental Model of Traumatic Brain Injury Detecting Acylcarnitines as Injury Related Markers

Khalil Mallah , Jusal Quanico , Antonella Raffo-Romero , Tristan Cardon , Soulaimane Aboulouard
Analytical Chemistry, 2019, 91 (18), pp.11879-11887. ⟨10.1021/acs.analchem.9b02633⟩
Article dans une revue inserm-02941587v1
Image document

Distinct Protein Expression Networks are Activated in Microglia Cells after Stimulation with IFN-γ and IL-4

Daniele Vergara , Annamaria Nigro , Alessandro Romano , Stefania de Domenico , Marina Damato
Cells, 2019, 8 (6), pp.580. ⟨10.3390/cells8060580⟩
Article dans une revue inserm-02941561v1
Image document

Nuclei of HeLa cells interactomes unravel a network of ghost proteins involved in proteins translation

Tristan Cardon , Michel Salzet , Julien Franck , Isabelle Fournier
Biochimica et Biophysica Acta (BBA) - General Subjects, 2019, 1863 (10), pp.1458-1470. ⟨10.1016/j.bbagen.2019.05.009⟩
Article dans une revue inserm-02941645v1
Image document

The multiverse nature of epithelial to mesenchymal transition

Pasquale Simeone , Marco Trerotola , Julien Franck , Tristan Cardon , Marco Marchisio
Seminars in Cancer Biology, 2019, 58, pp.1-10. ⟨10.1016/j.semcancer.2018.11.004⟩
Article dans une revue inserm-02940760v1
Image document

NanoLC-MS coupling of liquid microjunction microextraction for on-tissue proteomic analysis

Jusal Quanico , Julien Franck , Tristan Cardon , Eric Leblanc , Maxence Wisztorski
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2017, 1865 (7), pp.891-900. ⟨10.1016/j.bbapap.2016.11.002⟩
Article dans une revue inserm-02940625v1