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Structure and dynamics of the two amphipathic arginine-rich peptides RW9 and RL9 in a lipid environment investigated by solid-state NMR and MD simulations.

Kristina Witte , Bjoern E S Olausson , Astrid Walrant , Isabel D Alves , Alexander Vogel
BBA - Biochimica et Biophysica Acta, 2013, 1828 ((2)), pp.824-33. ⟨10.1016/j.bbamem.2012.11.014⟩
Article dans une revue hal-00839914v1
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The role of tryptophans on the cellular uptake and membrane interaction of arginine-rich cell penetrating peptides

Marie-Lise Jobin , Marine Blanchet , Sarah Henry , Stéphane Chaignepain , Claude Manigand , et al.
Biochimica et Biophysica Acta:Biomembranes, 2014, 1848 (2), pp.593-602. ⟨10.1016/j.bbamem.2014.11.013⟩
Article dans une revue hal-01087623v1

Furin-cleaved ELA/Apela precursor displays tumor suppressor function in renal cell carcinoma through mTORC1 activation

Fabienne Soulet , Clément Bodineau , Katarzyna B Hooks , Jean Descarpentrie , Isabel Alves , et al.
Article dans une revue hal-02872084v1

Molecular partners for interaction and cell internalization of cell-penetrating peptides: how identical are they?

Astrid Walrant , Chérine Bechara , Isabel D Alves , Sandrine Sagan
Nanomedicine, 2012, 7 ((1)), pp.133-43. ⟨10.2217/nnm.11.165⟩
Article dans une revue hal-00659776v1

Different membrane behaviour and cellular uptake of three basic arginine-rich peptides

Astrid Walrant , Isabelle Correia , Chen-Yu Jiao , Olivier Lequin , Eric Bent , et al.
Biochimica et Biophysica Acta:Biomembranes, 2011, 1808 (1), pp.382-393. ⟨10.1016/j.bbamem.2010.09.009⟩
Article dans une revue istex hal-02467762v1

Interaction of Aβ 1–42 Amyloids with Lipids Promotes “Off-Pathway” Oligomerization and Membrane Damage

Sarah Henry , Hélène Vignaud , Claude Bobo , Marion Decossas , Oliver Lambert , et al.
Biomacromolecules, 2015, 16 (3), pp.944-950. ⟨10.1021/bm501837w⟩
Article dans une revue hal-02461526v1

Relationships between membrane binding, affinity and cell internalization efficacy of a cell-penetrating peptide: penetratin as a case study.

Isabel D Alves , Cherine Bechara , Astrid Walrant , Yefim Zaltsman , Chen-Yu Jiao , et al.
PLoS ONE, 2011, 6 (9), pp.e24096. ⟨10.1371/journal.pone.0024096⟩
Article dans une revue hal-00638823v1

Translocation and endocytosis for cell-penetrating peptide internalization.

Chen-Yu Jiao , Diane Delaroche , Fabienne Burlina , Isabel D Alves , Gérard Chassaing , et al.
Journal of Biological Chemistry, 2009, 284 ((49):), pp.33957-65. ⟨10.1074/jbc.M109.056309⟩
Article dans une revue hal-00627026v1

Comparing lipid photo-cross-linking efficacy of penetratin analogues bearing three different photoprobes: dithienyl ketone, benzophenone, and trifluoromethylaryldiazirine

Chen-Yu Jiao , Isabel D. Alves , Vanessa Point , Solange Lavielle , Sandrine Sagan , et al.
Bioconjugate Chemistry, 2010, 21 (2), pp.352-359. ⟨10.1021/bc900466q⟩
Article dans une revue hal-00595401v1
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Study of G-Protein Coupled Receptor Signaling in Membrane Environment by Plasmon Waveguide Resonance

Isabel D. Alves , Sophie Lecomte
Accounts of Chemical Research, 2019, 52 (4), pp.1059-1067. ⟨10.1021/acs.accounts.9b00007⟩
Article dans une revue hal-02381024v1

Cellular uptake and biophysical properties of galactose and/or tryptophan containing cell-penetrating peptides.

Pascaline Lécorché , Astrid Walrant , Fabienne Burlina , Laurence Dutot , Sandrine Sagan , et al.
BBA - Biochimica et Biophysica Acta, 2011, 1818 (3), pp.448-457. ⟨10.1016/j.bbamem.2011.12.003⟩
Article dans une revue hal-00660350v1

Impact of lipid polyunsaturation on dopamine D2 receptor activation and signaling

Isabel Alves , Rim Baccouch , Marie-Lise Jobin , Véronique De-Smedt-Peyrusse , Joyce Heuninck , et al.
14. EBSA congress, Jul 2023, Stockholm, Sweden. pp.115
Communication dans un congrès hal-04207254v1

Different membrane behaviour and cellular uptake of three basic arginine-rich peptides.

Astrid Walrant , Isabelle Correia , Chen-Yu Jiao , Olivier Lequin , Eric H Bent , et al.
Biochimica et Biophysica Acta - Molecular Cell Research, 2011, 1808 (1), pp.382-93. ⟨10.1016/j.bbamem.2010.09.009⟩
Article dans une revue istex hal-00599704v1

The genetic history of France

Aude Saint-Pierre , Joanna Giemza , Isabel Alves , Matilde Karakachoff , Marinna Gaudin , et al.
European Journal of Human Genetics, 2020, 28 (7), pp.853-865. ⟨10.1038/s41431-020-0584-1⟩
Article dans une revue hal-02480238v1

Is there anybody in there? On the mechanisms of wall crossing of cell penetrating peptides.

Isabel D Alves , Astrid Walrant , Chérine Bechara , Sandrine Sagan
Current Protein and Peptide Science, 2012, 13 (7), pp.658-671. ⟨10.2174/138920312804142174⟩
Article dans une revue hal-00750131v1
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Design, synthesis, and biological evaluation of a multifunctional neuropeptide-Y conjugate for selective nuclear delivery of radiolanthanides

Adrien Chastel , Dennis Worm , Isabel Alves , Delphine Vimont , Melina Petrel , et al.
EJNMMI Research, 2020, 10 (1), ⟨10.1186/s13550-020-0612-8⟩
Article dans une revue hal-03082079v1
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Bidirectional transfer of Engrailed homeoprotein across the plasma membrane requires PIP2

Irène Amblard , Edmond Dupont , Isabel D. Alves , Julie Miralvès , Isabelle Queguiner , et al.
Journal of Cell Science, 2020, ⟨10.1101/2020.01.21.913566⟩
Article dans une revue hal-03082837v1

Erratum: Visualization of lipids and proteins at high spatial and temporal resolution via interferometric scattering (iSCAT) microscopy

Susann Spindler , Jens Ehrig , Katharina König , Tristan Nowak , Marek Piliarik , et al.
Journal of Physics D: Applied Physics, 2016, 49 (34), pp.349601. ⟨10.1088/0022-3727/49/34/349601⟩
Article dans une revue hal-01383250v1

Use of plasmon waveguide resonance (PWR) spectroscopy for examining binding, signaling and lipid domain partitioning of membrane proteins.

Victor J Hruby , Isabel Alves , Scott Cowell , Zdzislaw Salamon , Gordon Tollin
Life Sciences, 2010, 86 (15-16), pp.569-74. ⟨10.1016/j.lfs.2009.02.027⟩
Article dans une revue istex hal-00595358v1

Analysis of an intact G-protein coupled receptor by MALDI-TOF mass spectrometry: molecular heterogeneity of the tachykinin NK-1 receptor.

Isabel D Alves , Emmanuelle Sachon , Gerard Bolbach , Lynda Millstine , Solange Lavielle , et al.
Analytical Chemistry, 2007, 79 ((6)), pp.2189-98. ⟨10.1021/ac062415u⟩
Article dans une revue istex hal-00678722v1

A proapoptotic peptide conjugated to penetratin selectively inhibits tumor cell growth.

Isabel D Alves , Manon Carré , Marie-Pierre Montero , Sabine Castano , Sophie Lecomte , et al.
BBA - Biochimica et Biophysica Acta, 2014, 1838 (8), pp.2087-2098. ⟨10.1016/j.bbamem.2014.04.025⟩
Article dans une revue hal-00989572v1
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Putative interaction site for membrane phospholipids controls activation of TRPA1 channel at physiological membrane potentials

Lucie Macikova , Viktor Sinica , Anna Kadkova , Sandrine Villette , Alexandre Ciaccafava , et al.
FEBS Journal, 2019, 286 (18), pp.3664-3683. ⟨10.1111/febs.14931⟩
Article dans une revue hal-03082890v1

Functional Amyloids in Health and Disease

Dursun Nizam Korkut , Isabel Alves , Alexander Vogel , Sandrine Chabas , Cynthia M. Sharma , et al.
Journal of Molecular Biology, 2018, 430 (20), pp.3629-3630. ⟨10.1016/j.jmb.2018.07.024⟩
Article dans une revue hal-02412759v1

Cholesterol impacts chemokine CCR5 receptor ligand‐binding activity

Pierre Calmet , Christophe Cullin , Sandra Cortès , Maylou Vang , Nada Caudy , et al.
FEBS Journal, 2020, 287 (11), pp.2367-2385. ⟨10.1111/febs.15145⟩
Article dans une revue hal-03370902v1
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Impact of membrane lipid polyunsaturation on dopamine D2 receptor ligand binding and signalling

Marie-Lise Jobin , Véronique de Smedt-Peyrusse , Fabien Ducrocq , Rim Baccouch , Asma Oummadi , et al.
Molecular Psychiatry, 2023, 28 (5), pp.1960-1969. ⟨10.1038/s41380-022-01928-6⟩
Article dans une revue hal-04286162v2

Structural studies of HIV-1 Gag p6ct and its interaction with Vpr determined by solution nuclear magnetic resonance.

Gilmar F Salgado , Rodrigue Marquant , Alexander Vogel , Isabel D Alves , Scott E Feller , et al.
Biochemistry, 2009, 48 ((11)), pp.2355-67. ⟨10.1021/bi801794v⟩
Article dans une revue hal-00639520v1
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Ionpair-π interactions favor cell penetration of arginine/tryptophan-rich cell-penetrating peptides

Astrid Walrant , Antonio Bauzá , Claudia Girardet , Isabel D Alves , Sophie Lecomte , et al.
Biochimica et Biophysica Acta:Biomembranes, 2020, 1862 (2), pp.183098. ⟨10.1016/j.bbamem.2019.183098⟩
Article dans une revue hal-02346557v1

A Pathway Toward Tumor Cell-Selective CPPs?

Isabel D. Alves , Manon Carré , Solange Lavielle
Ülo Langel. Cell-Penetrating Peptides. Methods in Molecular Biology, 1324, Humana Press; Springer, pp.279-301, 2015, Methods in Molecular Biology, 978-1-4939-2805-7. ⟨10.1007/978-1-4939-2806-4_18⟩
Chapitre d'ouvrage hal-01362702v1

The Role of Membranes in the Organization of HIV-1 Gag p6 and Vpr: p6 Shows High Affinity for Membrane Bilayers Which Substantially Increases the Interaction between p6 and Vpr.

Gilmar Salgado , Alexander Vogel , Rodrigue Marquant , Scott Feller , Serge Bouaziz , et al.
Journal of Medicinal Chemistry, 2009, 52 (22), pp.7157-7162. ⟨10.1021/jm901106t⟩
Article dans une revue hal-02122420v1
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Interaction of the Anti-Proliferative GPER Inverse Agonist ERα17p with the Breast Cancer Cell Plasma Membrane: From Biophysics to Biology

Michaël Trichet , Rosamaria Lappano , Mathilde Belnou , Lilian Shadai Salazar Vazquez , Isabel Alves , et al.
Cells, 2020, 9 (2), pp.447. ⟨10.3390/cells9020447⟩
Article dans une revue hal-02493985v1