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Rôle de la NADPH oxydase 1 dans la régulation de la migration des cellules d'adénocarcinomes coliques HT29-D4

A. Sadok , Véronique Bourgarel-Rey , F Gattacceca , C. Penel , Hervé O Kovacic
Journées scientifiques sur « Tour d'horizon sur la signalisation intégrines et cadhérines » , Institut Albert Bonniot, Mar 2006, Grenoble, France
Communication dans un congrès hal-00019970v1

Tau regulates the microtubule-dependent migration of glioblastoma cells via the Rho-ROCK signaling pathway

Gilles Breuzard , Alessandra Pagano , Sonia Bastonero , Soazig Malesinski , Fabrice Parat , et al.
Journal of Cell Science, 2019, pp.jcs.222851. ⟨10.1242/jcs.222851⟩
Article dans une revue hal-01987458v1
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Myotoxin-3 from the Pacific Rattlesnake Crotalus oreganus oreganus Venom Is a New Microtubule-Targeting Agent

María Cecilia González García , Caroline Radix , Claude Villard , Gilles Breuzard , Pascal Mansuelle , et al.
Molecules, In press, 27, ⟨10.3390/molecules27238241⟩
Article dans une revue hal-03870782v2

Subverted regulation of Nox1 NADPH oxidase-dependent oxidant generation by protein disulfide isomerase A1 in colon carcinoma cells with overactivated KRas

Tiphany Coralie de Bessa , Alessandra Pagano , Ana Iochabel Soares Moretti , Percillia Victoria Santos Oliveira , Samir Andrade Mendonça , et al.
Cell Death and Disease, 2019, 10 (2), pp.143. ⟨10.1038/s41419-019-1402-y⟩
Article dans une revue hal-02158563v1

SARS-CoV-2-Induced Neurological Disorders in Symptomatic Covid-19 and Long Covid Patients: Key Role of Brain Renin-Angiotensin System

Ziad Fajloun , Hervé O Kovacic , Cédric Annweiler , Yingliang Wu , Zhijian Cao , et al.
Infectious Disorders - Drug Targets, 2022, 22, ⟨10.2174/1871526522666220406124618⟩
Article dans une revue hal-03635172v1

Counter-Regulatory Renin-Angiotensin System: An Important Line of Research to Understand and Limit the Severity of COVID-19

Cédric Annweiler , Zhijian Cao , Nicolas Papon , Hervé O Kovacic , Jean-Marc Sabatier
Infectious Disorders - Drug Targets, 2021, 21, ⟨10.2174/1871526521666210910063227⟩
Article dans une revue hal-03346158v1

NADPH Oxidase 1 Controls the Persistence of Directed Cell Migration by a Rho-Dependent Switch of 2/ 3 Integrins

Amine Sadok , Anne Pierres , Laetitia Dahan , Charles Prevot , Maxime Lehmann , et al.
Molecular and Cellular Biology, 2009, 29 (14), pp.3915 - 3928. ⟨10.1128/MCB.01199-08⟩
Article dans une revue hal-01744730v1
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Angiotensin II Type I Receptor (AT1R): The Gate towards COVID-19-Associated Diseases

George El-Arif , Shaymaa Khazaal , Antonella Farhat , Julien Harb , Cédric Annweiler , et al.
Molecules, 2022, 27 (7), pp.2048. ⟨10.3390/molecules27072048⟩
Article dans une revue hal-03617732v1
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The Pathophysiology of Long COVID throughout the Renin-Angiotensin System

Shaymaa Khazaal , Julien Harb , Mohamad Rima , Cédric Annweiler , Yingliang Wu , et al.
Molecules, 2022, 27 (9), pp.2903. ⟨10.3390/molecules27092903⟩
Article dans une revue hal-03982146v1

Why can high-level athletes develop very severe or fatal forms after intense exercise following SARS-CoV-2 infection or anti-Covid vaccination?

Ziad Fajloun , Ziad Abi Khattar , Hervé Kovacic , Christian Legros , Jean-Marc Sabatier
Infectious Disorders - Drug Targets, 2023, 23, ⟨10.2174/1871526523666230111104355⟩
Article dans une revue hal-03936219v1

Parkinson disease: Protective role and function of neuropeptides

Mireille Tabikh , Charbel Chahla , Nathalie Okdeh , Hervé O Kovacic , Jean-Marc Sabatier , et al.
Peptides, 2022, 151, pp.170713. ⟨10.1016/j.peptides.2021.170713⟩
Article dans une revue hal-03566584v1
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Tau Regulates Glioblastoma Progression, 3D Cell Organization, Growth and Migration via the PI3K-AKT Axis

Alessandra Pagano , Gilles Breuzard , Fabrice Parat , Aurelie Tchoghandjian , Dominique Figarella‑branger , et al.
Cancers, 2021, 13 (22), pp.5818. ⟨10.3390/cancers13225818⟩
Article dans une revue hal-03470226v1

PIVL, a snake venom Kunitz-type serine protease inhibitor, inhibits in vitro and in vivo angiogenesis.

Maram Morjen , Stéphane Honoré , Amine Bazaa , Zaineb Abdelkafi-Koubaa , Ameneallah Ellafi , et al.
Microvascular Research, 2014, 95, pp.149-56. ⟨10.1016/j.mvr.2014.08.006⟩
Article dans une revue pasteur-01061175v1

Gq-coupled Purinergic Receptors Inhibit Insulin-like Growth Factor-I/Phosphoinositide 3-Kinase Pathway-dependent Keratinocyte Migration

Salma Taboubi , Françoise Garrouste , Fabrice Parat , Gilbert Pommier , Emilie Faure , et al.
Molecular Biology of the Cell, 2010, 21 (6), pp.946 - 955. ⟨10.1091/mbc.E09-06-0497⟩
Article dans une revue hal-01744711v1

Overexpression of a Novel Noxo1 Mutant Increases Ros Production and Noxo1 Relocalisation

Fatima-Zahra Benssouina , Fabrice Parat , C Villard , Ludovic Leloup , Françoise Garrouste , et al.
International Journal of Molecular Sciences, 2023, 24 (5), pp.4663. ⟨10.3390/ijms24054663⟩
Article dans une revue hal-04009317v1

Counter-regulatory ‘Renin-Angiotensin’ System-based Candidate Drugs to Treat COVID-19 Diseases in SARS-CoV-2-infected Patients

Cédric Annweiler , Zhijian Cao , Yingliang Wu , Emmanuelle Faucon , Stéphanie Mouhat , et al.
Infectious Disorders - Drug Targets, 2020, 20 (4), pp.407-408. ⟨10.2174/1871526520666200518073329⟩
Article dans une revue hal-03357854v1

EPR spin trapping evaluation of ROS production in human fibroblasts exposed to cerium oxide nanoparticles: Evidence for NADPH oxidase and mitochondrial stimulation

Marcel Culcasi , Laila Benameur , Anne Mercier , Céline Lucchesi , Hidayat Rahmouni , et al.
Chemico-Biological Interactions, 2012, 199, pp.161. ⟨10.1016/j.cbi.2012.08.007⟩
Article dans une revue istex hal-01142816v1
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Editorial: Venoms, Animal and Microbial Toxins

Zhijian Cao , Jing-Lin Wang , Patrick Michael Mcnutt , Yuri Utkin , Delavar Shahbazzadeh , et al.
Frontiers in Pharmacology, 2021, 12, pp.706573. ⟨10.3389/fphar.2021.706573⟩
Article dans une revue hal-03358007v1
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Oxidation of Ca 2+ -Binding Domain of NADPH Oxidase 5 (NOX5): Toward Understanding the Mechanism of Inactivation of NOX5 by ROS

Irina A Petrushanko , Vladimir A Lobachev , Alexey A Kononikhin , Alexander A Makarov , François O Devred , et al.
Article dans une revue hal-01478543v1

2020, A Decisive Decade for NADPH Oxidases Inhibitors

Hervé O Kovacic
Antioxidants and Redox Signaling, 2020, 33 (5), pp.329-331. ⟨10.1089/ars.2020.8069⟩
Article dans une revue hal-02975872v1
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Isolation of an Anti–tumour Disintegrin: Dabmaurin–1, a Peptide Lebein–1–like, from Daboia mauritanica Venom

Florence Chalier , Laura Mugnier , Marion Tarbe , Soioulata Aboudou , Claude Villard , et al.
Toxins, 2020, 12 (2), pp.102. ⟨10.3390/toxins12020102⟩
Article dans une revue hal-03082260v1

Modulation of cellular redox state underlies antagonism between oxaliplatin and cetuximab in human colorectal cancer cell lines

Laetitia Dahan , Amine Sadok , Jean-Louis Formento , Jean François Seitz , Hervé Kovacic
British Journal of Pharmacology, 2009, 158 (2), pp.610 - 620. ⟨10.1111/j.1476-5381.2009.00341.x⟩
Article dans une revue hal-01744726v1

Gα(q/11)-coupled P2Y 2 nucleotide receptor inhibits human keratinocyte spreading and migration

Salma Taboubi , Julie Milanini , Estelle Delamarre , Fabrice Parat , Françoise Garrouste , et al.
FASEB Journal, 2007, 21 (14), pp.4047 - 4058. ⟨10.1096/fj.06-7476com⟩
Article dans une revue hal-01744755v1
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Oxidation of Са2+-Binding Domain of NADPH Oxidase 5 (NOX5): Toward Understanding the Mechanism of Inactivation of NOX5 by ROS

Irina Yu Petrushanko , Vladimir A Lobachev , Alexey A Kononikhin , Alexander Makarov , François O Devred , et al.
PLoS ONE, 2016, 11 (7), pp.e0158726. ⟨10.1371/journal.pone.0158726⟩
Article dans une revue hal-01744694v1
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The effects of caffeic, coumaric and ferulic acids on proliferation, superoxide production, adhesion and migration of human tumor cells in vitro

Nouha Nasr Bouzaiene , Soumaya Kilani-Jaziri , Hervé Kovacic , Leila Chekir-Ghedira , Kamel Ghedira , et al.
European Journal of Pharmacology, 2015, 766, pp.99-105
Article dans une revue hal-01481645v1
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Tau Protein as Therapeutic Target for Cancer? Focus on Glioblastoma

Rayane Hedna , Hervé Kovacic , Alessandra Pagano , Vincent Peyrot , Maxime Robin , et al.
Cancers, 2022, 14 (21), pp.5386. ⟨10.3390/cancers14215386⟩
Article dans une revue hal-03837788v1

Protein Disulfide Isomerase Is Required for Platelet-derived Growth Factor-induced Vascular Smooth Muscle Cell Migration, Nox1 NADPH Oxidase Expression, and RhoGTPase Activation

Luciana Pescatore , Diego Bonatto , Fábio Forti , Amine Sadok , Hervé Kovacic , et al.
Journal of Biological Chemistry, 2012, 287 (35), pp.29290 - 29300. ⟨10.1074/jbc.M112.394551⟩
Article dans une revue hal-01744702v1
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The Renin-Angiotensin System: A Key Role in SARS-CoV-2-Induced COVID-19

George El-Arif , Antonella Farhat , Shaymaa Khazaal , Cédric Annweiler , Hervé O Kovacic , et al.
Molecules, 2021, 26 (22), pp.6945. ⟨10.3390/molecules26226945⟩
Article dans une revue hal-03566588v1
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Inhibitor of Apoptosis Proteins Determine Glioblastoma Stem-Like Cells Fate in an Oxygen-Dependent Manner

Aurélie Soubéran , Jessica Cappaï , Mathieu Chocry , Christopher Nuccio , Julie Raujol , et al.
STEM CELLS, 2019, 37 (6), pp.731-742. ⟨10.1002/stem.2997⟩
Article dans une revue hal-02090843v1

Reversion of resistance to oxaliplatin by inhibition of p38 MAPK in colorectal cancer cell lines: involvement of the calpain / Nox1 pathway

Mathieu Chocry , Ludovic Leloup , Hervé Kovacic
Oncotarget, 2017, 8 (61), pp.103710-103730. ⟨10.18632/oncotarget.21780⟩
Article dans une revue hal-01741020v1