Hervé Guillou

CV Hervé Guillou Directeur de Recherche INRAE

161

Documents

Affiliations actuelles

Identifiants chercheurs

herve-guillou-inrae

Présentation

**Hervé Guillou (INRAE Toulouse)** **Born in Brest 13/09/1975** **herve.guillou@inrae.fr** **https://orcid.org/0000-0002-5363-9081** **Since 2018:** Member of unit board of directors (UMR1331 INRAE Toulouse) **Since 2016:** Senior investigator (DR) INRAE Toulouse, ToxAlim **Since 2009:** Group leader, “Integrative Toxicology and Metabolism”, INRAE ToxAlim **2008:** Junior investigator (CR) INRAE Toulouse, Molecular Pharmacology (Dir: Dr T. Pineau) **2004 –2007:** Post-doctoral scientist at Babraham Institute (Cambridge UK) Cell Signaling department (led by Dr L.R. Stephens et Dr P.T. Hawkins) **2000- 2004:** Assistant lecturer in biochemistry, Agrocampus Rennes **Degrees** **2014:** HDR – Toulouse University (France) **2004**: PhD in biochemistry and Cell Biology (Rennes University, France) **2000**: MSc in Physiology (Rennes University, France) **Teaching and training** **Teaching:** Pre-clinical Toxicology, Molecular endocrinology, Metabolism, Physiology and Hepatology, Lipid Biochemistry (MSc, University of Toulouse) **PhD Supervised (and current position):** Dr Simon Ducheix (PhD 2014; PI INSERM Nantes), Dr Alexia Buis (PhD 2018; started her own company), Dr Marion Régnier (PhD 2018; Post-doc, Institut Cochin), Dr Sarra Smati (MD, PhD 2019; Assistant Professor, University of Nantes), Dr Tiffany Fougeray (PhD 2020; Post-doc, Harvard Medical School), Dr Léonie Dopavogui (PhD 2021; Industry, Canada). **Post-doctoral scientist (and current position):** Dr Normand Podechard (2009-2011; Professor Rennes University of Pharmacy), Dr Alexandra Montagner (2011-2016; Principal Investigator INSERM Toulouse), Dr Anne Fougerat (2017-2021; Principal Investigator INRAE Toulouse), Dr Elena Piccinin (2022; Assistant Professor, University of Bari). **Fundings & Awards** Young scientist award from the French Society of Nutrition in 2014 Awards from the Francophone Society of Diabetes in 2015 and 2019 **Fundings:** ANR, ARC, INCA, SFD, SFN, AFEF, Occitanie, ANSES, FRM, EU (JPI) **Publications & Communication** 80 talks including selected oral communications at international meetings (Keystone Symposium; EMBO Meeting, EASD, EASL) 110 peer reviewed publications in international journals Full publication list available at [https://scholar.google.fr/citations?user=Toi0KcYAAAAJ&hl=fr](https://scholar.google.fr/citations?user=Toi0KcYAAAAJ&hl=fr)

Publications

	p110α-dependent hepatocyte signaling is critical for liver gene expression and its rewiring in MASLD Marion Régnier , Arnaud Polizzi , Tiffany Fougeray , Anne Fougerat , Prunelle Perrier BioRxiv, 2024, ⟨10.1101/2024.01.09.574858⟩ Article dans une revue hal-04442467v1
	The interplay between dietary fatty acids and gut microbiota influences host metabolism and hepatic steatosis Marc Schoeler , Sandrine Ellero-Simatos , Till Birkner , Jordi Mayneris-Perxachs , Lisa Olsson Nature Communications, 2023, 14 (1), pp.5329. ⟨10.1038/s41467-023-41074-3⟩ Article dans une revue hal-04197137v1
	Physiopathologie de la stéatose hépatique non-alcoolique (NAFLD) Lucia Parlati , Marion Régnier , Catherine Postic , Hervé Guillou Médecine des Maladies Métaboliques, 2023, in press, ⟨10.1016/j.mmm.2023.03.005⟩ Article dans une revue hal-04066670v1
	C/EBPα Confers Dependence to Fatty Acid Anabolic Pathways and Vulnerability to Lipid Oxidative Stress–Induced Ferroptosis in FLT3 -Mutant Leukemia Marie Sabatier , Rudy Birsen , Laura Lauture , Sarah Mouche , Paolo Angelino Cancer Discovery, 2023, 13 (7), pp.1720-1747. ⟨10.1158/2159-8290.CD-22-0411⟩ Article dans une revue hal-04166110v1
	Obesity promotes fumonisin B1 hepatotoxicity Léonie Dopavogui , Marion Régnier , Arnaud Polizzi , Quentin Ponchon , Sarra Smati Science of the Total Environment, 2023, 891, pp.164436. ⟨10.1016/j.scitotenv.2023.164436⟩ Article dans une revue hal-04112262v1
	Monoacylglycerol lipase reprograms hepatocytes and macrophages to promote liver regeneration Manon Allaire , Rola Al-Sayegh , Morgane Mabire , Adel Hammoutene , Matthieu Siebert JHEP Reports Innovation in Hepatology, 2023, 5 (8), pp.100794. ⟨10.1016/j.jhepr.2023.100794⟩ Article dans une revue hal-04178833v1
	ATGL-dependent white adipose tissue lipolysis controls hepatocyte PPARα activity Anne Fougerat , Gabriele Schoiswohl , Arnaud Polizzi , Marion Régnier , Carina Wagner Cell Reports, 2022, 39 (10), ⟨10.1016/j.celrep.2022.110910⟩ Article dans une revue hal-03695833v1
	Monoacylglycerol lipase inhibition specifically in macrophages compromises liver regeneration by inducing interferon type 1 that negatively impacts on hepatocyte proliferation Manon Allaire , Rola Al-Sayegh , Morgane Mabire , Matthieu Siebert , Mathilde Cadoux Journal of Hepatology, 2022, 77, pp.S65 Article dans une revue hal-03765301v1
	Reduction in gut‐derived MUFAs via intestinal stearoyl‐CoA desaturase 1 deletion drives susceptibility to NAFLD and hepatocarcinoma Simon Ducheix , Elena Piccinin , Claudia Peres , Oihane Garcia-Irigoyen , Justine Bertrand-Michel Hepatology Communications, 2022, ⟨10.1002/hep4.2053⟩ Article dans une revue hal-03758408v1
	Integrative study of diet-induced mouse models of NAFLD identifies PPARα as a sexually dimorphic drug target Sarra Smati , Arnaud Polizzi , Anne Fougerat , Sandrine Ellero-Simatos , Yuna Blum Gut, 2022, 71 (4), pp.807-821. ⟨10.1136/gutjnl-2020-323323⟩ Article dans une revue hal-03215969v1
	Evidence for constitutive microbiota-dependent short-term control of food intake in mice: Is there a link with inflammation, oxidative stress, endotoxemia, and Glp-1? Selma Ben Fradj , Emmanuelle Nédélec , Juliette Salvi , Mélanie Fouesnard , Marine Huillet Antioxidants and Redox Signaling, 2022, 37 (4-6), pp.349-369. ⟨10.1089/ars.2021.0095⟩ Article dans une revue hal-03594297v1
	Tissular Genomic Responses to Oral FB1 Exposure in Pigs Léonie Dopavogui , Arnaud Polizzi , Anne Fougerat , Pascal Gourbeyre , Chloé Terciolo Toxins, 2022, 14 (2), pp.83. ⟨10.3390/toxins14020083⟩ Article dans une revue hal-03609600v1
	Prospective association between dietary pesticide exposure profiles and type 2 diabetes risk in the NutriNet-Santé cohort Pauline Rebouillat , Rodolphe Vidal , Jean-Pierre Cravedi , Bruno Taupier-Letage , Laurent Debrauwer Environmental Health, 2022, 21 (1), pp.57. ⟨10.1186/s12940-022-00862-y⟩ Article dans une revue hal-03689933v1
	NMR-based metabolic profiling and discrimination of wild tropical tunas by species, size category, geographic origin, and on-board storage condition Nathalie Bodin , Aurélien Amiel , Edwin Fouché , Fany Sardenne , Emmanuel Chassot Food Chemistry, 2022, 371, ⟨10.1016/j.foodchem.2021.131094⟩ Article dans une revue hal-03376705v1
	Zac1 and the Imprinted Gene Network program juvenile NAFLD in response to maternal metabolic syndrome Marine Baptissart , Christine Bradish , Brie Jones , Evan Walsh , Jesse Tehrani Hepatology, 2022, in press, ⟨10.1002/hep.32363⟩ Article dans une revue hal-03602068v1
	The hepatocyte insulin receptor is required to program the liver clock and rhythmic gene expression Tiffany Fougeray , Arnaud Polizzi , Marion Régnier , Anne Fougerat , Sandrine Ellero-Simatos Cell Reports, 2022, 39 (2), pp.110674. ⟨10.1016/j.celrep.2022.110674⟩ Article dans une revue hal-03647009v1
	The pregnane X receptor drives sexually dimorphic hepatic changes in lipid and xenobiotic metabolism in response to gut microbiota in mice Sharon Barretto , Frédéric Lasserre , Marine Huillet , Marion Régnier , Arnaud Polizzi Microbiome, 2021, 9, ⟨10.1186/s40168-021-01050-9⟩ Article dans une revue hal-03209709v1
	Endoplasmic reticulum stress controls iron metabolism through TMPRSS6 repression and hepcidin mRNA stabilization by RNA-binding protein HuR Audrey Belot , Ophélie Gourbeyre , Anais Palin , Aude Rubio , Amélie Largounez Haematologica, 2021, 106 (4), pp.1202-1206. ⟨10.3324/haematol.2019.237321⟩ Article dans une revue hal-02911817v1
	New targets for NAFLD Lucia Parlati , Marion Régnier , Hervé Guillou , Catherine Postic JHEP Reports Innovation in Hepatology, 2021, 3 (6), pp.100346. ⟨10.1016/j.jhepr.2021.100346⟩ Article dans une revue hal-03472343v1
	Dual regulation of TxNIP by ChREBP and FoxO1 in liver Bénédicte Noblet , Fadila Benhamed , Insug O-Sullivan , Wenwei Zhang , Gaelle Filhoulaud iScience, 2021, 24 (3), pp.102218. ⟨10.1016/j.isci.2021.102218⟩ Article dans une revue hal-03176271v1
	Oxidative Stress in NAFLD: Role of Nutrients and Food Contaminants Clémence Rives , Anne Fougerat , Sandrine Ellero-Simatos , Nicolas Loiseau , Hervé Guillou Biomolecules, 2020, 10 (12), pp.1702. ⟨10.3390/biom10121702⟩ Article dans une revue hal-03100801v1
	Perinatal exposure to a dietary pesticide cocktail does not increase susceptibility to high-fat diet-induced metabolic perturbations at adulthood but modifies urinary and fecal metabolic fingerprints in C57Bl6/J mice Lorraine Smith , Wendy Klement , Léonie Dopavogui , Frédéric de Bock , Frédéric Lasserre Environment International, 2020, 144, pp.106010. ⟨10.1016/j.envint.2020.106010⟩ Article dans une revue hal-02912899v1
	Important Considerations for Sample Collection in Metabolomics Studies with a Special Focus on Applications to Liver Functions Lorraine Smith , Joran Villaret-Cazadamont , Sandrine P Claus , Cécile Canlet , Hervé Guillou Metabolites, 2020, 10 (3), pp.104. ⟨10.3390/metabo10030104⟩ Article dans une revue hal-02556806v1
	Regulation of hepatokine gene expression in response to fasting and feeding: Influence of PPARa and insulin-dependent signaling in hepatocytes Sarra Smati , Marion Régnier , Tiffany Fougeray , Arnaud Polizzi , Anne Fougerat Diabetes & Metabolism, 2020, 46 (2), pp.129-136. ⟨10.1016/j.diabet.2019.05.005⟩ Article dans une revue hal-02402566v1
	Peroxisome Proliferator-Activated Receptors and Their Novel Ligands as Candidates for the Treatment of Non-Alcoholic Fatty Liver Disease Anne Fougerat , Alexandra Montagner , Nicolas Loiseau , Hervé Guillou , Walter Wahli Cells, 2020, 9 (7), pp.1638. ⟨10.3390/cells9071638⟩ Article dans une revue hal-02899682v1
	Peroxisome Proliferator-Activated Receptors and Caloric Restriction-Common Pathways Affecting Metabolism, Health, and Longevity Kalina Duszka , András Gregor , Hervé Guillou , Jürgen König , Walter Wahli Cells, 2020, 9, ⟨10.3390/cells9071708⟩ Article dans une revue hal-02904081v1
	Author correction: Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor Céline Lukowicz , Sandrine Ellero-Simatos , Marion Régnier , Fabiana Oliviero , Frédéric Lasserre Scientific Reports, 2020, 10 (1), ⟨10.1038/s41598-020-61226-5⟩ Article dans une revue hal-02627769v1
	Hepatocyte-specific deletion of Pparα promotes NAFLD in the context of obesity Marion Régnier , Arnaud Polizzi , Sarra Smati , Céline Lukowicz , Anne Fougerat Scientific Reports, 2020, 10 (1), pp.6489. ⟨10.1038/s41598-020-63579-3⟩ Article dans une revue inserm-02875414v1
	Proton NMR enables the absolute quantification of aqueous metabolites and lipid classes in unique mouse liver samples Aurélien Amiel , Marie Tremblay-Franco , Roselyne Gautier , Simon Ducheix , Alexandra Montagner Metabolites, 2020, 10 (1), 20 p. ⟨10.3390/metabo10010009⟩ Article dans une revue hal-02622894v1
	Selective Liver Estrogen Receptor Modulation Prevents Steatosis, Diabetes, and Obesity Through the Anorectic Growth Differentiation Factor 15 Hepatokine in Mice Maeva Guillaume , Elodie Riant , Aurelie Fabre , Isabelle Raymond-Letron , Melissa Buscato Hepatology Communications, 2019, 3 (7), pp.908-924. ⟨10.1002/hep4.1363⟩ Article dans une revue hal-02277993v1
	Sphingolipid metabolism in non-alcoholic fatty liver diseases Marion Régnier , Arnaud Polizzi , Hervé Guillou , Nicolas Loiseau Biochimie, 2019, 159, pp.9-22. ⟨10.1016/j.biochi.2018.07.021⟩ Article dans une revue hal-02626541v1
	PGC-1 alpha induced browning promotes involution and inhibits lactation in mammary glands Elena Piccinin , Annalisa Morgano , Claudia Peres , Annalisa Contursi , Justine Bertrand-Michel Cellular and Molecular Life Sciences, 2019, 76 (24), pp.5011-5025. ⟨10.1007/s00018-019-03160-y⟩ Article dans une revue hal-02622923v1
	Interaction between Hormone-Sensitive Lipase and ChREBP in Fat Cells Controls Insulin Sensitivity Pauline Morigny , Marianne Houssier , Aline Mairal , Claire Ghilain , Etienne Mouisel Nature Metabolism, 2019, 1 (1), pp.133-146. ⟨10.1038/s42255-018-0007-6⟩ Article dans une revue inserm-02150261v1
	β-catenin oncogenic activation rewires fatty acid catabolism to fuel hepatocellular carcinoma Alexandra Montagner , Laurent Le Cam , Hervé Guillou Gut, 2019, 68 (2), pp.183-185. ⟨10.1136/gutjnl-2018-316557⟩ Article dans une revue hal-02448229v1
	Coelomocytes regulate starvation-induced fat catabolism and lifespan extension through the lipase LIPL-5 in Caenorhabditis elegans Alexia Buis , Stéphanie Bellemin , Jérôme Goudeau , Léa Monnier , Nicolas Loiseau Cell Reports, 2019, 28 (4), 1041-1049 + 6 p. ⟨10.1016/j.celrep.2019.06.064⟩ Article dans une revue hal-02628480v1
	Hepatic PPARalpha is critical in the metabolic adaptation to sepsis Réjane Paumelle , Joël Haas , Nathalie Hennuyer , Eric Baugé , Yann Deleye Journal of Hepatology, 2019, 70 (5), pp.963-973. ⟨10.1016/j.jhep.2018.12.037⟩ Article dans une revue inserm-02109735v1
	Depletion of gram-positive bacteria impacts hepatic biological functions during the light phase Hui Yun Penny Oh , Sandrine Ellero-Simatos , Ravikumar Manickam , Nguan Soon Tan , Hervé Guillou International Journal of Molecular Sciences, 2019, 20 (4), 28 p. ⟨10.3390/ijms20040812⟩ Article dans une revue hal-02620345v1
	Gene expression profiling reveals that PXR activation inhibits Hhepatic PPAR alpha activity and decreases FGF21 secretion in male C57Bl6/J mice Sharon Barretto , Frédéric Lasserre , Anne Fougerat , Lorraine Smith , Tiffany Fougeray International Journal of Molecular Sciences, 2019, 20 (15), ⟨10.3390/ijms20153767⟩ Article dans une revue hal-02617929v1
	The class 3 PI3K coordinates autophagy and mitochondrial lipid catabolism by controlling nuclear receptor PPARα Anton Iershov , Ivan Nemazanyy , Chantal Alkhoury , Muriel Girard , Esther Barth Nature Communications, 2019, 10 (1), 18 p. ⟨10.1038/s41467-019-09598-9⟩ Article dans une revue hal-02622186v1
	The protective role of liver X receptor (LXR) during fumonisin B1-induced hepatotoxicity Marion Régnier , Arnaud Polizzi , Céline Lukowicz , Sarra Smati , Frédéric Lasserre Archives of Toxicology, 2019, 93 (2), pp.505-517. ⟨10.1007/s00204-018-2345-2⟩ Article dans une revue hal-02619117v1
	Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor Céline Lukowicz , Sandrine Ellero-Simatos , Marion Régnier , Fabiana Oliviero , Frédéric Lasserre Scientific Reports, 2019, 9 (1), ⟨10.1038/s41598-019-56570-0⟩ Article dans une revue hal-02428712v1
	Inhibition of monoacylglycerol lipase, an anti-inflammatory and antifibrogenic strategy in the liver Aida Habib , Dina Chokr , Jinghong Wan , Pushpa Hegde , Morgane Mabire Gut, 2019, 68 (3), pp.522-532. ⟨10.1136/gutjnl-2018-316137⟩ Article dans une revue hal-02963612v1
	Early life stress induces type 2 diabetes-like features in ageing mice Hanna Ilchmann-Diounou , Maïwenn Olier , Corinne Lencina , Ambre Riba , Sharon Barretto Brain, Behavior, and Immunity, 2019, 80, pp.452-463. ⟨10.1016/j.bbi.2019.04.025⟩ Article dans une revue hal-02627238v1
	The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity Julien Bricambert , Marie-Clotilde Alves-Guerra , Pauline Esteves , Carina Prip-Buus , Justine Bertrand-Michel Nature Communications, 2018, 9 (1), ⟨10.1038/s41467-018-04361-y⟩ Article dans une revue hal-02122655v1
	Dual extraction of mRNA and lipids from a single biological sample Normand Podechard , Simon Ducheix , Arnaud Polizzi , Frédéric Lasserre , Alexandra Montagner Scientific Reports, 2018, 8 (1), pp.7019. ⟨10.1038/s41598-018-25332-9⟩ Article dans une revue hal-01794296v1
	Intracellular lipids are an independent cause of liver injury and chronic kidney disease in non alcoholic fatty liver disease-like context Laure Monteillet , Monika Gjorgjieva , Marine Silva , Vincent Verzieux , Linda Imikirene Molecular metabolism, 2018, 16, pp.100-115. ⟨10.1016/j.molmet.2018.07.006⟩ Article dans une revue inserm-02339561v1
	40 Ar/ 39 Ar age of cryptochron C2r.2r-1 as recorded in a lava sequence within the Ko'olau volcano (Hawaii, USA) Hervé Guillou , Vincent Scao , Sébastien Nomade Quaternary Geochronology, 2018, 43, pp.91 - 101. ⟨10.1016/j.quageo.2017.10.005⟩ Article dans une revue hal-01806763v1
	Complementary intestinal mucosa and microbiota responses to caloric restriction Kalina Duszka , Sandrine Ellero-Simatos , Ghim Siong Ow , Marianne Defernez , Eeswari Paramalingam Scientific Reports, 2018, 8, ⟨10.1038/s41598-018-29815-7⟩ Article dans une revue hal-02621482v1
	Metabolic effects of a chronic dietary exposure to a low-dose oesticide cocktail in mice: Sexual dimorphism and role of the constitutive androstane receptor Céline Lukowicz , Sandrine Ellero-Simatos , Marion Régnier , Arnaud Polizzi , Frédéric Lasserre Environmental Health Perspectives, 2018, 126 (6), 18 p. ⟨10.1289/EHP2877⟩ Article dans une revue hal-02624889v1
	Type 2 diabetes prevention through hormone sensitive lipase inhibition: elongase ELOVL6 at the center of attention P. Morigny , M. Houssier , E. Mouisel , A. Mairal , S. Caspar-Bauguil Diabetologia, 2017, 60, pp.S249 Article dans une revue hal-02624062v1
	Glycerol-3-phosphate acyltransferase 2 expression modulates cell roughness and membrane permeability: An atomic force microscopy study Elizabeth R. Cattaneo , Eduardo Prieto , Maria B. Garcia-Fabiani , Mauro A. Montanaro , Hervé Guillou PLoS ONE, 2017, 12 (12), 18 p. ⟨10.1371/journal.pone.0189031⟩ Article dans une revue hal-02622165v1
	Selective activation of estrogen receptor alpha activation function-1 is sufficient to prevent obesity, steatosis, and insulin resistance in mouse Maeva Guillaume , Sandra Handgraaf , Aurelie J Fabre , Isabelle Raymond-Letron , Elodie Riant American Journal of Pathology, 2017, 187 (6), pp.1273-1287. ⟨10.1016/j.ajpath.2017.02.013⟩ Article dans une revue hal-01603827v1
	Insights into the role of hepatocyte PPARα activity in response to fasting Marion Régnier , Arnaud Polizzi , Yannick Lippi , Edwin Fouché , Géraldine Michel Molecular and Cellular Endocrinology, 2017, in press, ⟨10.1016/j.mce.2017.07.035⟩ Article dans une revue hal-01605514v1
	A Specific ChREBP and PPARα Cross-Talk Is Required for the Glucose-Mediated FGF21 Response Alison Iroz , Alexandra Montagner , Fadila Benhamed , Françoise Levavasseur , Arnaud Polizzi Cell Reports, 2017, 21 (2), pp.403 - 416. ⟨10.1016/j.celrep.2017.09.065⟩ Article dans une revue hal-01837159v1
	Dietary oleic acid regulates hepatic lipogenesis through a liver X receptor-dependent signaling Simon Ducheix , Alexandra Montagner , Arnaud Polizzi , Frédéric Lasserre , Marion Régnier PLoS ONE, 2017, 12 (7), ⟨10.1371/journal.pone.0181393⟩ Article dans une revue hal-01606929v1
	Identification of signaling pathways targeted by the food contaminant FB1: Transcriptome and kinome analysis of samples from pig liver and intestine Marion Régnier , Pascal Gourbeyre , Philippe Pinton , Scott Napper , Joëlle Laffitte Molecular Nutrition and Food Research, 2017, in press (12), 42 p. ⟨10.1002/mnfr.201700433⟩ Article dans une revue hal-01606651v1
	Transcriptional control of physiological and pathological processes by the nuclear receptor PPAR beta/delta Nguan Soon Tan , Manuel Vázquez-Carrera , Alexandra Montagner , Ming Keat Sng , Hervé Guillou Progress in Lipid Research, 2016, 64, pp.98-122. ⟨10.1016/j.plipres.2016.09.001⟩ Article dans une revue hal-01594607v1
	Hepatic circadian clock oscillators and nuclear receptors integrate microbiome-derived signals Alexandra Montagner , Agata Korecka , Arnaud Polizzi , Yannick Lippi , Yuna Blum Scientific Reports, 2016, 6 (1), pp.1-14. ⟨10.1038/srep20127⟩ Article dans une revue hal-01482816v1
	Localizing the lipid products of PI3Kγ in neutrophils Laura Norton , Yvonne Lindsay , Arnaud Deladeriere , Tamara Chessa , Hervé Guillou Advances in Biological Regulation, 2016, 60, pp.36-45. ⟨10.1016/j.jbior.2015.10.005⟩ Article dans une revue hal-01602482v1
	Effects of pesticide mixtures in human and animal models: an update of the recent literature Virginie Rizzati , O. Briand , Hervé Guillou , Laurence Gamet-Payrastre Chemico-Biological Interactions, 2016, 254, pp.231-246. ⟨10.1016/j.cbi.2016.06.003⟩ Article dans une revue hal-02637756v1
	Glucocorticoid receptor-PPAR alpha axis in fetal mouse liver prepares neonates for milk lipid catabolism Gianpaolo Rando , Chek Kun Tan , Nourhène Khaled , Alexandra Montagner , Nicolas Leuenberger eLife, 2016, 5, 31 p. ⟨10.7554/eLife.11853⟩ Article dans une revue hal-01602433v1
	Intestinal PPAR gamma signalling is required for sympathetic nervous system activation in response to caloric restriction Kalina Duszka , Alexandre Picard , Sandrine Ellero-Simatos , Jiapeng Chen , Marianne Defernez Scientific Reports, 2016, 6, ⟨10.1038/srep36937⟩ Article dans une revue hal-01606898v1
	Hepatic fasting-induced PPAR alpha activity does not depend on essential fatty acids Arnaud Polizzi , Edwin Fouché , Simon Ducheix , Frédéric Lasserre , Alice Marmugi International Journal of Molecular Sciences, 2016, 17 (10), pp.1624. ⟨10.3390/ijms17101624⟩ Article dans une revue hal-01476503v1
	White-to-brite conversion in human adipocytes promotes metabolic reprogramming towards fatty acid anabolic and catabolic pathways V Barquissau , D. Beuzelin , D. Pisani , G.E. Beranger , A. Mairal Molecular metabolism, 2016, 5 (5), pp.352-365. ⟨10.1016/j.molmet.2016.03.002⟩ Article dans une revue hal-02134884v1
	Activation of the Constitutive Androstane Receptor induces hepatic lipogenesis and regulates Pnpla3 gene expression in a LXR-independent way Alice Marmugi , Céline Lukowicz , Frédéric Lasserre , Alexandra Montagner , Arnaud Polizzi Toxicology and Applied Pharmacology, 2016, 303, pp.90 - 100. ⟨10.1016/j.taap.2016.05.006⟩ Article dans une revue hal-01837194v1
	Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD Alexandra Montagner , Arnaud Polizzi , Edwin Fouché , Simon Ducheix , Yannick Lippi Gut, 2016, 65 (7), pp.1202-1214. ⟨10.1136/gutjnl-2015-310798⟩ Article dans une revue inserm-02339685v1
	The suppression of hepatic glucose production improves metabolism and insulin sensitivity in subcutaneous adipose tissue in mice Sylvie Casteras , Aya Abdul-Wahed , Maud Soty , Fanny Vulin , Hervé Guillou Diabetologia, 2016, 59 (12), pp.2645-2653. ⟨10.1007/s00125-016-4097-y⟩ Article dans une revue hal-01606287v1
	Novel Grb14-Mediated Cross Talk between Insulin and p62/Nrf2 Pathways Regulates Liver Lipogenesis and Selective Insulin Resistance Lucie Popineau , Lucille Morzyglod , Nadege Carre , Michele Cauzac , Pascale Bossard Molecular and Cellular Biology, 2016, 36 (16), pp.2168 - 2181. ⟨10.1128/MCB.00170-16⟩ Article dans une revue hal-01602453v1
	The gut microbiota: a major player in the toxicity of environmental pollutants? Sandrine P. Claus , Hervé Guillou , Sandrine Ellero-Simatos npj Biofilms and Microbiomes, 2016, 2, ⟨10.1038/npjbiofilms.2016.3⟩ Article dans une revue hal-01602371v1
	Perilipin 5 fine-tunes lipid oxidation to metabolic demand and protects against lipotoxicity in skeletal muscle Claire Laurens , Virginie Bourlier , Aline Mairal , Katie Louche , Pierre-Marie Badin Scientific Reports, 2016, 6, ⟨10.1038/srep38310⟩ Article dans une revue hal-01605047v1
	New insights into the organ-specific adverse effects of fumonisin B1 Nicolas Loiseau , Arnaud Polizzi , Aude Dupuy , Nicole Therville , Mirindra Rakotonirainy Archives of Toxicology, 2015, 89 (9), pp.1619-1629. ⟨10.1007/s00204-014-1323-6⟩ Article dans une revue hal-03331305v1
	Combined QTL and selective sweep mappings with coding SNP annotation and cis-eQTL analysis revealed PARK2 and JAG2 as new candidate genes for adiposity regulation. Pierre-François Roux , Simon Boitard , Anne Blum , Brian Parks , Alexandra Montagner G3, 2015, 5, pp.517-529. ⟨10.1534/g3.115.016865⟩ Article dans une revue hal-01194040v1
	Effect of obesity and metabolic syndrome on plasma oxysterols and fatty acids in human Marie Tremblay-Franco , Chiara Zerbinati , Antonio Pacelli , Giuseppina Palmaccio , Carla Lubrano Steroids, 2015, 99 (Part B), pp.287-292. ⟨10.1016/j.steroids.2015.03.019⟩ Article dans une revue hal-02639945v1
	Protective effects of n-6 fatty acids-enriched diet on intestinal ischaemia/reperfusion injury involve lipoxin A4 and its receptor Thomas Gobbetti , Simon Ducheix , Pauline Le Faouder , Teresa Pérez-Berezo , Fabien Riols British Journal of Pharmacology, 2015, 172 (3), pp.910-923. ⟨10.1111/bph.12957⟩ Article dans une revue hal-01601458v1
	A link between hepatic glucose production and peripheral energy metabolism via hepatokines. Aya Abdul-Wahed , Amandine Gautier-Stein , Sylvie Casteras , Maud Soty , Damien Roussel Molecular metabolism, 2014, 3 (5), pp.531-543. ⟨10.1016/j.molmet.2014.05.005⟩ Article dans une revue inserm-01350728v1
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	A systems biology approach to the hepatic role of the oxysterol receptor LXR in the regulation of lipogenesis highlights a cross-talk with PPARα. Simon Ducheix , Normand Podechard , Frédéric Lasserre , Arnaud Polizzi , Aurélien Pommier Biochimie, 2013, 95 (3), pp.556-67. ⟨10.1016/j.biochi.2012.09.028⟩ Article dans une revue inserm-00872582v1
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	The liver X receptor: A master regulator of the gut-liver axis and a target for non alcoholic fatty liver disease Simon Ducheix , Alexandra Montagner , Vassilia Theodorou , Laurent Ferrier , Hervé Guillou Biochemical Pharmacology, 2013, 86 (1), pp.96 - 105. ⟨10.1016/j.bcp.2013.03.016⟩ Article dans une revue hal-02646839v1
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	PI3K beta Plays a Critical Role in Neutrophil Activation by Immune Complexes Suhasini Kulkarni , Cassian Sitaru , Zoltan Jakus , Karen E. Anderson , George Damoulakis Science Signaling, 2011, 4 (168), pp.ra23. ⟨10.1126/scisignal.2001617⟩ Article dans une revue hal-02649985v1
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	ELOVL2 controls the level of n-6 28:5 and 30:5 fatty acids in testis, a prerequisite for male fertility and spermmaturation in mice Damir Zadravec , Petr Tvrdik , Hervé Guillou , Rilchard Haslam , Tsutomu Kobayash Journal of Lipid Research, 2011, 52 (2), pp.245-255. ⟨10.1194/jlr.M011346⟩ Article dans une revue hal-01137032v1
	Liver X Receptor: an oxysterol sensor and a major playerin the control of lipogenesis Simon Ducheix , J.M.A. Lobaccaro , Pascal G.P. Martin , Hervé Guillou Chemistry and Physics of Lipids, 2011, 164 (6), pp.500-14. ⟨10.1016/j.chemphyslip.2011.06.004⟩ Article dans une revue hal-02651993v1
	Regulation of LPCAT3 by LXR. O. Demeure , Frédéric Lecerf , C. Duby , Colette Désert , S. Ducheix Gene, 2011, 470 (1-2), pp.7-11. ⟨10.1016/j.gene.2010.09.002⟩ Article dans une revue hal-00729271v1
	Cooperativity between Integrin Activation and Mechanical Stress Leads to Integrin Clustering. Olivier Ali , Hervé Guillou , Olivier Destaing , Corinne Albiges-Rizo , Marc R. Block Biophysical Journal, 2011, 100 (11), pp.2595-604. ⟨10.1016/j.bpj.2011.03.028⟩ Article dans une revue inserm-00605002v1
	ARAP3 binding to phosphatidylinositol-(3,4,5)-trisphosphate depends on N-terminal tandem PH domains and adjacent sequences Helen E. Craig , John Coadwell , Hervé Guillou , Sonja Vermeren Cellular Signalling, 2010, 22 (2), pp.257-264. ⟨10.1016/j.cellsig.2009.09.025⟩ Article dans une revue hal-02662592v1
	Ablation of the very-long-chain fatty acid elongase ELOVL3 in mice leads to constrained lipid storage and resistance to diet-induced obesity Damir Zadravec , Annelie Brolinson , Rachel M. Fisher , Claes Carneheim , Robert I. Csikasz FASEB Journal, 2010, 24 (11), pp.4366 - 4377. ⟨10.1096/fj.09-152298⟩ Article dans une revue hal-02662422v1
	Di-(2-ethylhexyl)-phthalate (DEHP) activates the Constitutive Androstane Receptor (CAR): a novel signalling pathway sensitive to phthalates Alexandre Eveillard , Laila Mselli-Lakhal , Ariane Mogha , Frédéric Lasserre , Arnaud Polizzi Biochemical Pharmacology, 2009, 77 (11), pp.1735. ⟨10.1016/j.bcp.2009.02.023⟩ Article dans une revue hal-00493499v1
	Liver X receptor alpha regulates fatty acid synthase expression in chicken. O. Demeure , C. Duby , Colette Désert , S. Assaf , Dominique Hazard Poultry Science, 2009, 88 (12), pp.2628-35. ⟨10.3382/ps.2009-00258⟩ Article dans une revue hal-00730008v1
	Identification of potential mechanisms of toxicity after di-(2-ethylhexyl)-phthalate (DEHP) adult exposure in the liver using a systems biology approach Alexandre Eveillard , Frédéric Lasserre , M de Tayrac , Arnaud Polizzi , S Claus Toxicology and Applied Pharmacology, 2009, 236 (3), pp.282-292. ⟨10.1016/j.taap.2009.02.008⟩ Article dans une revue hal-02662270v1
	A minimal model for hepatic fatty acid balance during fasting: Application to PPAR alpha-deficient mice Pierre Blavy , Florence Gondret , Hervé Guillou , Sandrine Lagarrigue , P.G.P. Martin Journal of Theoretical Biology, 2009, 261 (2), pp.266. ⟨10.1016/j.jtbi.2009.07.025⟩ Article dans une revue hal-00559147v1
	FSH-stimulated PTEN activity accounts for the lack of FSH mitogenic effect in prepubertal rat Sertoli cells Joëlle Dupont , Astrid Musnier , Jérémy Decourtye , Thomas Boulo , Charlotte Lécureuil Molecular and Cellular Endocrinology, 2009, 315 (1-2), pp.271. ⟨10.1016/j.mce.2009.09.016⟩ Article dans une revue hal-00547657v1
	Transcriptional regulation of hepatic fatty acid metabolism Hervé Guillou , Pg Martin , Thierry Pineau Sub-cellular biochemistry, 2008, 49, pp.3-47 Article dans une revue hal-02653666v1
	Novel aspects of PPARα-mediated regulation of lipid and xenobiotic metabolism revealed through a nutrigenomic study Pascal G.P. Martin , Hervé Guillou , Frédéric Lasserre , Sébastien Dejean , Annaig Lan Hepatology, 2007, 45 (3), pp.767-777. ⟨10.1002/hep.21510⟩ Article dans une revue hal-00661808v1
	Novel aspects of PPAR alpha-mediated regulation of lipid and xenobiotic metabolism revealed through a nutrigenomic study. P.G.P. Martin , Hervé Guillou , F. Lasserre , S. Déjean , Annaig Lan Hepatology, 2007, 45, pp.667-677 Article dans une revue hal-02659352v1
	Myristic acid increases $\Delta$6-desaturase activity in cultured rat hepatocytes Sophie Jan , Hervé Guillou , Sabine d'Andrea , Stéphanie Daval , Monique Bouriel Reproduction Nutrition Development, 2004, 44 (2), pp.131-140. ⟨10.1051/rnd:2004020⟩ Article dans une revue hal-00900482v1
	Although it is rapidly metabolized in cultured rat hepatocytes, lauric acid is used for protein acylation Vincent V. Rioux , Stéphanie Daval , Hervé Guillou , Sophie Jan , Philippe P. Legrand Reproduction Nutrition Development, 2003, 43 (5), pp.419-430. ⟨10.1051/rnd:2003036⟩ Article dans une revue hal-00900517v1
	Effects of dietary fatty acids on the expression of an array of class II nuclear receptor target genes P. Martin , Hervé Guillou , F. Lasserre , Cécile Calléja , Sophie Jan Drug Metabolism Reviews, 2003, 35 (178), pp.89 Article dans une revue hal-02674247v1
	Conversion of hexadecanoic acid to hexadecenoic acid by rat delta 6-desaturase Hervé Guillou , Vincent V. Rioux , Daniel D. Catheline , Jean-Noel J.-N. Thibault , Monique Bouriel Journal of Lipid Research, 2003, 44 (3), pp.450-454. ⟨10.1194/jlr.C200019-JLR200⟩ Article dans une revue hal-02678861v1
	The same rat delta 6-desaturase not only acts on 18- but also on 24-carbon fatty acids in very-long-chain polyunsaturated fatty acid biosynthesis Sabine d'Andrea , Hervé Guillou , Sophie Jan , Daniel D. Catheline , Jean-Noel J.-N. Thibault Biochemical Journal, 2002, 364, pp.49-55 Article dans une revue hal-02669429v1
	Hydrolysis of beta-casein by gastric proteases. 1. Comparison of proteolytic action of bovine chymosin and pepsin A Hervé Guillou , Guy Miranda , J.P. Pelissier International Journal of Peptide and Protein Research, 1991, 37, pp.494-501 Article dans une revue hal-02708181v1
	Analyse quantitative des caseines dans le lait de vache par chromatographie liquide rapide d'echanges d'ions (FPLC) Hervé Guillou , Guy Miranda , J.P. Pelissier Lait, 1987, 67 (2), pp.135-148 Article dans une revue hal-02721649v1
	Analyse quantitative des caséines dans le lait de vache par chromatographie liquide rapide d'échange d'ions (FPLC) Hervé Guillou , G. Miranda , J.-P. Pelissier Le Lait, 1987, 67 (2), pp.135-148 Article dans une revue hal-00929097v1
	Analyse quantitative des caseines dans le lait de vache par chromatographie liquide rapide d'echange d'ions (FPLC) Hervé Guillou , Guy Miranda , J.P. Pelissier Lait, 1987, 67, pp.135-148 Article dans une revue hal-02719777v1
	Méthodes de dosage des protéines du lait de vache Hervé Guillou , J.P. Pelissier , R. Grappin Le Lait, 1986, 66 (2), pp.143-175 Article dans une revue hal-00929062v1
	Methodes de dosage des proteines du lait de vache Hervé Guillou , J.P. Pelissier , R. Grappin Lait, 1986, 66, pp.143-175 Article dans une revue hal-02718097v1

	Effets d’une exposition alimentaire, périnatale et chronique alimentaire, à des doses réglementaires de glyphosate sur l’axe microbiote intestinal-intestin-foie Lorraine Smith , Céline Martin , Sabrine Naimi , Beatrice Engelmann , Frédéric Lasserre 13ème congrès annuel de la Société Francophone de Santé et Environnement, Nov 2022, Valence, France Communication dans un congrès hal-03775382v1
	Early life stress induces type 2 diabetes-like features in ageing mice Hanna Ilchmann-Diounou , Maïwenn Olier , Corinne Lencina , Ambre Riba , Sharon Barretto NeuroGASTRO 2019 Congress, Sep 2019, Lisbon, Portugal. 1 p Communication dans un congrès hal-02736934v1
	Sex dimorphic role of estrogen receptor a in physiological regulation of hepatic metabolism Blandine Tramunt , Sarra Smati , Naia Grandgeorge , Anne Fougerat , Maxime Guillaume 55. Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), Sep 2019, Barcelona, Spain. 1 p Communication dans un congrès hal-02734566v1
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	Influence of gender on progression of liver metabolic diseases in response to different nutritional challenges Sarra Smati , Arnaud Polizzi , Marion Régnier , Alain Marrot , Céline Lukowicz 54. Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), European Association for the Study of Diabetes (EASD). GBR., Oct 2018, Berlin, Germany. pp.1 Communication dans un congrès hal-02735253v1
	Hepatokines in metabolic disease: novel insights into FGF21 regulation by glucose Catherine Postic , Alison Iroz , Alexandra Montagner , Fadila Benhamed , Arnaud Polizzi 52. Annual Scientific Meeting of the European Society for Clinical Investigation “Precision medicine for healthy ageing”, May 2018, Barcelone, Spain. pp.1 Communication dans un congrès hal-02734271v1
	Constitutive Androstane Receptor deficiency leads to sexually dimorphic metabolic disorders in aging Céline Lukowicz , Marion Régnier , Frédéric Lasserre , Arnaud Polizzi , Alexandra Montagner 54. Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), European Association for the Study of Diabetes (EASD). GBR., Oct 2018, Berlin, France. pp.1 Communication dans un congrès hal-02735254v1
	Hepatocyte PI3Kα controls the PPARα-FGF21 axis and regulates whole body fatty acid homeostasis Marion Régnier , Arnaud Polizzi , Céline Lukowicz , S. Smati , Anne Fougerat European Assocation for the Study of Diabetes (EASD), Oct 2018, Berlin, Germany Communication dans un congrès hal-04442612v1
	Early life stress induces type 2 diabetes at adulthood in male mice Hanna Ilchmann-Diounou , Maïwenn Olier , Corinne Lencina , Sandrine Ellero-Simatos , Ambre Riba 10. International Meeting of Pediatric Endocrinology, Sep 2017, Washington, United States Communication dans un congrès hal-01603069v1
	Hepatocyte PI3Kα controls the PPARα-FGF21 axis and regulates whole body fatty acid homeostasis Marion Régnier , Arnaud Polizzi , Céline Lukowicz , Edwin Fouché , Frédéric Lasserre EMBO meeting, Apr 2017, Majorqua, Spain Communication dans un congrès hal-04442626v1
	Chronic maternal separation in mice impaired immuno-metabolism in older offspring on standard diet Hanna Ilchmann-Diounou , Corinne Lencina , Sandrine Ellero-Simatos , Ambre Riba , Cherryl Harkat The Neonatal Window of Opportunity, Early Priming for Life, Herrenhausen Conference, Dec 2016, Hanovre, Germany Communication dans un congrès hal-01608144v1
	Specific modulation of hepatic estrogen receptor alpha prevents fatty liver but also obesity and insulin resistance induced by a high fat diet in mice Maeva Guillaume , Sandra Handgraaf , Isabelle Raymond-Letron , Aude Fabre , Elodie Riant 50th International Liver Congress of the European-Association-for-the-Study-of-the-Liver, European Association for the Study of the Liver (EASL). Genève, CHE., Apr 2015, Vienne, Austria. 1 p Communication dans un congrès hal-02743029v1
	Partial inhibition of hormone-sensitive lipase improves insulin sensitivity by induction of de novo lipogenesis and elongase ELOVL6 in human adipocytes Pauline Morigny , Marianne Houssier , Sylvie Caspar Bauguil , Diane Beuzelin , Aline Mairal 51. Annual Meeting of the European Association for the Study of Diabetes (EASD), European Association for the Study of Diabetes (EASD). Düsseldorf, GBR., Sep 2015, Stockholm, Sweden. 2 p Communication dans un congrès hal-02744175v1
	Contribution of the nuclear receptors PXR and CAR to gene expression modulations induced by fipronil in rodent liver Béatrice Roques , Marlène Z. Lacroix , Nabila Moussaoui , Julien Leghait , Sylvie Puel 4th Health Food Symposium, Pôle Aliment Sécurité Sanitaire & Santé (PA3S)., 2012, Toulouse, France Communication dans un congrès hal-02802231v1
	Contribution of the nuclear receptors PXR and CAR to gene expression modulations induced by fipronil in rodent liver Béatrice Roques , Marlène Z. Lacroix , Nabila Moussaoui , Julien Leghait , Sylvie Puel 12th International Congress of the European Association for Veterinary Pharmacology and Toxicology (EAVPT), Jul 2012, Noordwijkerhout, Netherlands. pp.1-182 Communication dans un congrès hal-02744689v1
	Rôle de LXR dans le métabolisme des acides gras Hervé Guillou Institut Cochin, Institut Cochin. Dr Catherine Postic, Ville service, FRA., Mar 2011, Cochin, France Communication dans un congrès hal-02802820v1
	ELOVL2 controls the level of n-628:5 and 30:5 fatty acids in testis, a prerequisite for male fertility and sperm maturation in mice Damir Zadravec , Petr Tvrdik , Hervé Guillou , Richard Haslam , Tsutomu Kobayashi 52. International Conference on the Bioscience of Lipids : Expanding the Horizons of Lipidomics, International Conference on the Bioscience of Lipids (ICBL). INT., Aug 2011, Varsovie, Poland. ⟨10.1016/j.chemphyslip.2011.05.035⟩ Communication dans un congrès hal-02747851v1
	L’expression d’une forme active de ChREBP conduit à la réinduction de la lipogenèse dans un modèle animal de déficience en LXR et SREBP-1c A. Poupeau , F. Rayah-Benhamed , R. Dentin , Hervé Guillou , .J. Girard 69èmes journées de l'Agence Française d’Etude du Foie, Saisissez le nom du laboratoire, du service ou du département., Ville service., Sep 2011, Paris, France Communication dans un congrès hal-02804525v1
	Regulation of hepatic lipid metabolism: effect of dietary fatty acids and effect of Bisphenol A Hervé Guillou Centre de Génomique Integrative de Lausanne, Centre de Génomique Integrative de Lausanne., Feb 2011, Lausanne, Switzerland Communication dans un congrès hal-02802819v1
	Role of LXR in hepatic fatty acid homeostasis revealed through a nutrigenomic approach Hervé Guillou Journées des récepteurs nucléaires, Muséum National d’Histoire Naturelle (MNHN). Saisissez le nom du laboratoire, du service ou du département., Paris, FRA., Mar 2011, Paris, France Communication dans un congrès hal-02802823v1
	Oxysterol signaling in fatty acid metabolism Hervé Guillou INSERM U915, L'institut du Thorax, Saisissez le nom du laboratoire, du service ou du département., Ville service., Jan 2011, Nantes, France Communication dans un congrès hal-02802818v1
	Régulation du Liver X Receptor par le fructose et développement de la stéatose hépatique Simon Ducheix , F Rayah-Benhamed , Alexandra Montagner , Arnaud Polizzi , Frédéric Lasserre 9. Journées Francophones de Nutrition (JFN), Ville service., Dec 2011, Reims, France Communication dans un congrès hal-02805683v1
	Integrating QTL controlling fatness, lipid metabolites and gene expressions to genetically dissect the adiposity complex trait in a meat chicken cross Yuna Blum , Olivier O. Demeure , Colette Désert , Hervé Guillou , J Bertrand-Michel 62. Annual Meeting of the European Association for Animal Production (EAAP), Aug 2011, Stavanger, Norway Communication dans un congrès hal-02748764v1
	An xosysterol sensor and a master regulator of lipogenesis Hervé Guillou ENOR meeting, Saisissez le nom du laboratoire, du service ou du département., Ville service., Sep 2011, Rome, Italy Communication dans un congrès hal-02802433v1
	Regulation of hepatic lipid metabolism: effect of dietary fatty acids and effect of Bisphenol A. Hervé Guillou ENS Lyon, Ecole Normale Supérieure (ENS). Dr Hugo Aguilaniu, Lyon, FRA., Apr 2011, Lyon, France Communication dans un congrès hal-02803044v1
	Power Allocation Problem in Charging Electric Vehicles with Photovoltaic Production Hervé Guillou , Van-Dat Cung , Duy Long Ha , Mireille Jacomino The 8th International Conference on Supply Chain Management and Information Systems (SCMIS2010), Oct 2010, Hong Kong, China. pp.720-725 Communication dans un congrès hal-00528686v1
	Nuclear receptors in the transcriptional control of hepatic fatty acid metabolism Hervé Guillou The Wenner-Gren Institute, University of Stockholm, Sep 2009, Stockholm, Sweden. pp.Inconnu Communication dans un congrès hal-02813403v1
	A minimal and dynamical model for fatty acid metabolism in mouse liver Pierre Blavy , Florence Gondret , Hervé Guillou , Sandrine Lagarrigue , Pascal G.P. Martin Journées Ouvertes Biologie Informatique Mathématiques, 2008, Lille, France. pp.Inconnu Communication dans un congrès hal-02817340v1
	A minimal and dynamic model for fatty acid metabolism in mouse liver Pierre Blavy , Florence Gondret , Hervé Guillou , Sandrine Lagarrigue , Pascal G.P. Martin Journées Ouvertes de Biologie, Informatique et Mathématique (JOBIM), Jun 2008, Lille, France Communication dans un congrès hal-02756716v1
	A minimal and dynamic model for fatty acid metabolism in mouse liver Pierre Blavy , Florence Gondret , Hervé Guillou , Sandrine Lagarrigue , Pascal G.P. Martin Journées Ouvertes de Biologie, Informatique et Mathématique (JOBIM), Jun 2008, Lille (FR), France Communication dans un congrès hal-00729742v1
	A kinetic view of coordinate modulations of gene expression and metabolism in wild-type and PPARa-/- mice during fasting Pgp Martin , R Barnouin , Frédéric Lasserre , Hervé Guillou , Michela Cantiello Cycles de conferences de l'IFR31, 2005, Toulouse, France. pp.Inconnu Communication dans un congrès hal-02832532v1
	A kinetic view of coordinate modulations of gene expression and metabolism in wild-type and PPARa-/- mice during fasting R Barnouin , Frédéric Lasserre , Michela Cantiello , Hervé Guillou , Thierry Pineau Gene signature symposia, 2005, Paris, France. pp.Inconnu Communication dans un congrès hal-02828236v1
	Empreintes transcriptionnelles de lipides alimentaires sur modèles souris Pascal G.P. Martin , Hervé Guillou , Frédéric Lasserre , S Dejean , P Legrand Analyse intégrée de signatures variées GENOTOUL, 2005, Toulouse, France. pp.Inconnu Communication dans un congrès hal-02825872v1
	PPARa remplit-il véritablement la fonction de senseur nutritionnel vis-à-vis des acides gras alimentaires ? Une étude comparée de signatures transcriptomique et lipidomique Pascal G.P. Martin , Frédéric Lasserre , Hervé Guillou , R Barnouin , S Dejean Journée GERLI de lipidomique, 2005, Toulouse, France. pp.Inconnu Communication dans un congrès hal-02829883v1
	Influence des acides gras alimentaires sur les voies de signalisation des récepteurs nucléaires : une étude comparée de signatures transcriptomique et lipidomique Pascal G.P. Martin , Frédéric Lasserre , Hervé Guillou , R Barnouin , S Dejean Journées Scientifiques du GIS « PA-3S », 2005, Boussens, France. pp.Inconnu Communication dans un congrès hal-02834051v1
	A kinetic view of coordinate modulations of gene expression and metabolism in wild type and PPARa-/- mice during fasting R Barnouin , Frédéric Lasserre , M Cantielo , Hervé Guillou , Thierry Pineau Conference of the Paul Hamel Institute / New developements in the metabolic syndrome, 2004, Monaco, France. pp.Inconnu Communication dans un congrès hal-02828078v1
	Caractérisation des effets hépatiques induits par les lipides alimentaires par analyse de leurs signatures biologiques chez la souris Pascal G.P. Martin , Hervé Guillou , Frédéric Lasserre , S Dejean , P Legrand Journée d’animation scientifique de l’IFR30, 2004, Toulouse, France. pp.Inconnu Communication dans un congrès hal-02825956v1
	Expression and activity of two recombinant isoforms of rat NMT1 Vincent V. Rioux , Frédérique F. Pédrono , Stéphanie Daval , Daniel D. Catheline , Monique Bouriel 6th Congress of International Society for the Study of Fatty Acids and Lipids (ISSFAL), Jun 2004, Brighton, United Kingdom Communication dans un congrès hal-03348632v1
	Characterization of hepatic effects induced by food lipids from the analysis of their biological signatures in mice Pascal G.P. Martin , Hervé Guillou , Frédéric Lasserre , A Paris , S Dejean Journée d’animation du Département d’Alimentation Humaine de l’INRA, 2004, Paris, France. pp.Inconnu Communication dans un congrès hal-02826237v1
	Is PPARa a true nutritional sensor for dietary fatty acids: a coordinate transcriptomic and lipidomic study Pascal G.P. Martin , Frédéric Lasserre , Hervé Guillou , R Barnouin , S Dejean Journée d’animation scientifique de l’IFR31, 2004, Toulouse, France. pp.Inconnu Communication dans un congrès hal-02829897v1
	Biological effects of nutrients : what interdisciplinary strategies to grasp and analyze complex signatures Pascal G.P. Martin , Frédéric Lasserre , Hervé Guillou , R Barnouin , S Dejean Journée d’animation du Département d’Alimentation Humaine de l’INRA, 2004, Paris, France. pp.Inconnu Communication dans un congrès hal-02833182v1
	Effects of dietary fatty acids on the expression of an array of class II nuclear receptor target genes Pascal G.P. Martin , Hervé Guillou , Frédéric Lasserre , Cécile Calléja , Sophie Jan Inconnu, 2003, pp.Inconnu Communication dans un congrès hal-02833157v1
	Regulation of hepatic desaturases by PPAR alpha Hervé Guillou , Pascal G.P. Martin , Sophie Jan , Sabine d'Andrea , Alain Roulet Inconnu, 2003, pp.Inconnu Communication dans un congrès hal-02832865v1
	Activité de la myristoyl-CoA: protéine N-myristoyltransférase de rat exprimée dans les cellules COS-7. Vincent V. Rioux , M. Ravache , Etienne Cognard , Stéphanie Daval , Hervé Guillou Groupe d’Etude et de Recherche sur les Lipides et les Lipoprotéines (GERLI), Diversité moléculaire et physiopathologie, Sep 2003, Paris, France Communication dans un congrès hal-03348639v1
	Effet des acides gras saturés sur l’activité et l’expression des D6- et D5-désaturases Sophie Jan , Hervé Guillou , Sabine d'Andrea , Stéphanie Daval , Emmanuelle Dumont 4èmes Journées Francophones de Nutrition, Nov 2002, Dijon, France Communication dans un congrès hal-03348641v1
	Modelisation de la digestion gastrique des proteines du lait Benedicte Savalle , P. Garnier , Guy Miranda , Hervé Guillou , J.P. Pelissier Journee d'automne d'information scientifique, Oct 1987, Jouy-en-Josas, France Communication dans un congrès hal-02783241v1

	Transcriptional regulation of hepatic fatty acid metabolism Hervé Guillou , Pgp Martin , Thierry Pineau Subcellular Biochemistry: Lipids in Health and Disease, Springer, 2009 Chapitre d'ouvrage hal-02815951v1

	Preuve de concept ARCHIPL: Bilan de l'évaluation in vitro de la rétention du déoxynivalénol par des parois de levure modifiées par hémisynthèse Nicolas Loiseau , Arnaud Polizzi , Frédéric Lasserre , Hervé Guillou , Marlène Z. Lacroix [Contrat] Inrae. 2014 Rapport hal-02801787v1

Hervé Guillou

Présentation

Publications

p110α-dependent hepatocyte signaling is critical for liver gene expression and its rewiring in MASLD

The interplay between dietary fatty acids and gut microbiota influences host metabolism and hepatic steatosis

Physiopathologie de la stéatose hépatique non-alcoolique (NAFLD)

C/EBPα Confers Dependence to Fatty Acid Anabolic Pathways and Vulnerability to Lipid Oxidative Stress–Induced Ferroptosis in FLT3 -Mutant Leukemia

Obesity promotes fumonisin B1 hepatotoxicity

Monoacylglycerol lipase reprograms hepatocytes and macrophages to promote liver regeneration

ATGL-dependent white adipose tissue lipolysis controls hepatocyte PPARα activity

Monoacylglycerol lipase inhibition specifically in macrophages compromises liver regeneration by inducing interferon type 1 that negatively impacts on hepatocyte proliferation

Reduction in gut‐derived MUFAs via intestinal stearoyl‐CoA desaturase 1 deletion drives susceptibility to NAFLD and hepatocarcinoma

Integrative study of diet-induced mouse models of NAFLD identifies PPARα as a sexually dimorphic drug target

Evidence for constitutive microbiota-dependent short-term control of food intake in mice: Is there a link with inflammation, oxidative stress, endotoxemia, and Glp-1?

Tissular Genomic Responses to Oral FB1 Exposure in Pigs

Prospective association between dietary pesticide exposure profiles and type 2 diabetes risk in the NutriNet-Santé cohort

NMR-based metabolic profiling and discrimination of wild tropical tunas by species, size category, geographic origin, and on-board storage condition

Zac1 and the Imprinted Gene Network program juvenile NAFLD in response to maternal metabolic syndrome

The hepatocyte insulin receptor is required to program the liver clock and rhythmic gene expression

The pregnane X receptor drives sexually dimorphic hepatic changes in lipid and xenobiotic metabolism in response to gut microbiota in mice

Endoplasmic reticulum stress controls iron metabolism through TMPRSS6 repression and hepcidin mRNA stabilization by RNA-binding protein HuR

New targets for NAFLD

Dual regulation of TxNIP by ChREBP and FoxO1 in liver

Oxidative Stress in NAFLD: Role of Nutrients and Food Contaminants

Perinatal exposure to a dietary pesticide cocktail does not increase susceptibility to high-fat diet-induced metabolic perturbations at adulthood but modifies urinary and fecal metabolic fingerprints in C57Bl6/J mice

Important Considerations for Sample Collection in Metabolomics Studies with a Special Focus on Applications to Liver Functions

Regulation of hepatokine gene expression in response to fasting and feeding: Influence of PPARa and insulin-dependent signaling in hepatocytes

Peroxisome Proliferator-Activated Receptors and Their Novel Ligands as Candidates for the Treatment of Non-Alcoholic Fatty Liver Disease

Peroxisome Proliferator-Activated Receptors and Caloric Restriction-Common Pathways Affecting Metabolism, Health, and Longevity

Author correction: Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor

Hepatocyte-specific deletion of Pparα promotes NAFLD in the context of obesity

Proton NMR enables the absolute quantification of aqueous metabolites and lipid classes in unique mouse liver samples

Selective Liver Estrogen Receptor Modulation Prevents Steatosis, Diabetes, and Obesity Through the Anorectic Growth Differentiation Factor 15 Hepatokine in Mice

Sphingolipid metabolism in non-alcoholic fatty liver diseases

PGC-1 alpha induced browning promotes involution and inhibits lactation in mammary glands

Interaction between Hormone-Sensitive Lipase and ChREBP in Fat Cells Controls Insulin Sensitivity

β-catenin oncogenic activation rewires fatty acid catabolism to fuel hepatocellular carcinoma

Coelomocytes regulate starvation-induced fat catabolism and lifespan extension through the lipase LIPL-5 in Caenorhabditis elegans

Hepatic PPARalpha is critical in the metabolic adaptation to sepsis

Depletion of gram-positive bacteria impacts hepatic biological functions during the light phase

Gene expression profiling reveals that PXR activation inhibits Hhepatic PPAR alpha activity and decreases FGF21 secretion in male C57Bl6/J mice

The class 3 PI3K coordinates autophagy and mitochondrial lipid catabolism by controlling nuclear receptor PPARα

The protective role of liver X receptor (LXR) during fumonisin B1-induced hepatotoxicity

Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor

Inhibition of monoacylglycerol lipase, an anti-inflammatory and antifibrogenic strategy in the liver

Early life stress induces type 2 diabetes-like features in ageing mice

The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity

Dual extraction of mRNA and lipids from a single biological sample

Intracellular lipids are an independent cause of liver injury and chronic kidney disease in non alcoholic fatty liver disease-like context

40 Ar/ 39 Ar age of cryptochron C2r.2r-1 as recorded in a lava sequence within the Ko'olau volcano (Hawaii, USA)

Complementary intestinal mucosa and microbiota responses to caloric restriction

Metabolic effects of a chronic dietary exposure to a low-dose oesticide cocktail in mice: Sexual dimorphism and role of the constitutive androstane receptor

Type 2 diabetes prevention through hormone sensitive lipase inhibition: elongase ELOVL6 at the center of attention

Glycerol-3-phosphate acyltransferase 2 expression modulates cell roughness and membrane permeability: An atomic force microscopy study

Selective activation of estrogen receptor alpha activation function-1 is sufficient to prevent obesity, steatosis, and insulin resistance in mouse

Insights into the role of hepatocyte PPARα activity in response to fasting

A Specific ChREBP and PPARα Cross-Talk Is Required for the Glucose-Mediated FGF21 Response

Dietary oleic acid regulates hepatic lipogenesis through a liver X receptor-dependent signaling

Identification of signaling pathways targeted by the food contaminant FB1: Transcriptome and kinome analysis of samples from pig liver and intestine

Transcriptional control of physiological and pathological processes by the nuclear receptor PPAR beta/delta

Hepatic circadian clock oscillators and nuclear receptors integrate microbiome-derived signals

Localizing the lipid products of PI3Kγ in neutrophils

Effects of pesticide mixtures in human and animal models: an update of the recent literature

Glucocorticoid receptor-PPAR alpha axis in fetal mouse liver prepares neonates for milk lipid catabolism

Intestinal PPAR gamma signalling is required for sympathetic nervous system activation in response to caloric restriction

Hepatic fasting-induced PPAR alpha activity does not depend on essential fatty acids

White-to-brite conversion in human adipocytes promotes metabolic reprogramming towards fatty acid anabolic and catabolic pathways

Activation of the Constitutive Androstane Receptor induces hepatic lipogenesis and regulates Pnpla3 gene expression in a LXR-independent way

Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD

The suppression of hepatic glucose production improves metabolism and insulin sensitivity in subcutaneous adipose tissue in mice

Novel Grb14-Mediated Cross Talk between Insulin and p62/Nrf2 Pathways Regulates Liver Lipogenesis and Selective Insulin Resistance

The gut microbiota: a major player in the toxicity of environmental pollutants?

Perilipin 5 fine-tunes lipid oxidation to metabolic demand and protects against lipotoxicity in skeletal muscle

New insights into the organ-specific adverse effects of fumonisin B1

Combined QTL and selective sweep mappings with coding SNP annotation and cis-eQTL analysis revealed PARK2 and JAG2 as new candidate genes for adiposity regulation.

Effect of obesity and metabolic syndrome on plasma oxysterols and fatty acids in human

Protective effects of n-6 fatty acids-enriched diet on intestinal ischaemia/reperfusion injury involve lipoxin A4 and its receptor

A link between hepatic glucose production and peripheral energy metabolism via hepatokines.

Adverse effects of long-term exposure to bisphenol A during adulthood leading to hyperglycaemia and hypercholesterolemia in mice

In vivo hepatic lipid quantification using MRS at 7 Tesla in a mouse model of glycogen storage disease type 1a