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111

CV Hervé Guillou Directeur de Recherche INRAE


Hervé Guillou

DR2 INRAE Toulouse

ToxAlim

 

 

2016 DR2 INRA Toulouse, UMR 1331 ToxAlim (Direction : Dr B. Salles)

 

 

 

2011 CR1 INRA Toulouse, UMR 1331 ToxAlim (Direction : Dr B. Salles)

 

 

 

2008 CR2 INRA Toulouse, Pharmacologie Moléculaire (Direction : Dr T. Pineau)

 

 

 

2004 - 2007 Chercheur post-doctoral, The Babraham Institute (Cambridge, UK), Cell signaling Department, Inositide Lab (Direction : Dr L.R. Stephens et Dr P.T. Hawkins)

 

 

 

2000 - 2004 Assistant d’Enseignement et de Recherche Contractuel, Laboratoire de Biochimie et Nutrition, Agrocampus Rennes (Direction : Dr P. Legrand)

 

 

 

1999 Ingénieur Stagiaire, Groupe Danone (Direction : Dr D. Dalgleish)

 


Journal articles67 documents

  • Clémence Rives, Anne Fougerat, Sandrine Eellero-Simatos, Nicolas Loiseau, Hervé Guillou, et al.. Oxidative Stress in NAFLD: Role of Nutrients and Food Contaminants. Biomolecules, MDPI, 2020, 10 (12), pp.1702. ⟨10.3390/biom10121702⟩. ⟨hal-03100801⟩
  • Céline Lukowicz, Sandrine Eellero-Simatos, Marion Regnier, Fabiana Oliviero, Frédéric Lasserre, et al.. Author correction: Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor. Scientific Reports, Nature Publishing Group, 2020, 10 (1), ⟨10.1038/s41598-020-61226-5⟩. ⟨hal-02627769⟩
  • Aurélien Amiel, Marie Tremblay Franco, Roselyne Gautier, Simon Ducheix, Alexandra Montagner, et al.. Proton NMR enables the absolute quantification of aqueous metabolites and lipid classes in unique mouse liver samples. Metabolites, MDPI, 2020, 10 (1), 20 p. ⟨10.3390/metabo10010009⟩. ⟨hal-02622894⟩
  • Marion Régnier, Arnaud Polizzi, Sarra Smati, Céline Lukowicz, Anne Fougerat, et al.. Hepatocyte-specific deletion of Pparα promotes NAFLD in the context of obesity. Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.6489. ⟨10.1038/s41598-020-63579-3⟩. ⟨inserm-02875414⟩
  • Sarra Smati, Marion Regnier, Tiffany Fougeray, Arnaud Polizzi, Anne Fougerat, et al.. Regulation of hepatokine gene expression in response to fasting and feeding: Influence of PPARa and insulin-dependent signaling in hepatocytes. Diabetes and Metabolism, Elsevier Masson, 2020, 46 (2), pp.129-136. ⟨10.1016/j.diabet.2019.05.005⟩. ⟨hal-02402566⟩
  • Marion Regnier, Arnaud Polizzi, Hervé Guillou, Nicolas Loiseau. Sphingolipid metabolism in non-alcoholic fatty liver diseases. Biochimie, Elsevier, 2019, pp.9-22. ⟨10.1016/j.biochi.2018.07.021⟩. ⟨hal-02626541⟩
  • Sharon Ann Barretto, Frédéric Lasserre, Anne Fougerat, Lorraine Smith, Tiffany Fougeray, et al.. Gene expression profiling reveals that PXR activation inhibits Hhepatic PPAR alpha activity and decreases FGF21 secretion in male C57Bl6/J mice. International Journal of Molecular Sciences, MDPI, 2019, 20 (15), ⟨10.3390/ijms20153767⟩. ⟨hal-02617929⟩
  • Alexia Buis, Stéphanie Bellemin, Jérôme Goudeau, Léa Monnier, Nicolas Loiseau, et al.. Coelomocytes regulate starvation-induced fat catabolism and lifespan extension through the lipase LIPL-5 in Caenorhabditis elegans. Cell Reports, Elsevier Inc, 2019, 28 (4), 1041-1049 + 6 p. ⟨10.1016/j.celrep.2019.06.064⟩. ⟨hal-02628480⟩
  • Anton Iershov, Ivan Nemazanyy, Chantal Alkhoury, Muriel Girard, Esther Barth, et al.. The class 3 PI3K coordinates autophagy and mitochondrial lipid catabolism by controlling nuclear receptor PPARα. Nature Communications, Nature Publishing Group, 2019, 10 (1), 18 p. ⟨10.1038/s41467-019-09598-9⟩. ⟨hal-02622186⟩
  • Elena Piccinin, Annalisa Morgano, Claudia Peres, Annalisa Contursi, Justine Bertrand-Michel, et al.. PGC-1 alpha induced browning promotes involution and inhibits lactation in mammary glands. Cellular and Molecular Life Sciences, Springer Verlag, 2019, 76 (24), pp.5011-5025. ⟨10.1007/s00018-019-03160-y⟩. ⟨hal-02622923⟩
  • Hanna Ilchmann-Diounou, Maïwenn Olier, Corinne Lencina, Ambre Riba, Sharon Barretto, et al.. Early life stress induces type 2 diabetes-like features in ageing mice. Brain, Behavior, and Immunity, Elsevier, 2019, 80, pp.452-463. ⟨10.1016/j.bbi.2019.04.025⟩. ⟨hal-02627238⟩
  • Hui Yun Penny Oh, Sandrine Ellero-Simatos, Ravikumar Manickam, Nguan Soon Tan, Hervé Guillou, et al.. Depletion of gram-positive bacteria impacts hepatic biological functions during the light phase. International Journal of Molecular Sciences, MDPI, 2019, 20 (4), 28 p. ⟨10.3390/ijms20040812⟩. ⟨hal-02620345⟩
  • Marion Regnier, Arnaud Polizzi, Céline Lukowicz, Sarra Smati, Frédéric Lasserre, et al.. The protective role of liver X receptor (LXR) during fumonisin B1-induced hepatotoxicity. Archives of Toxicology, Springer Verlag, 2019, 93 (2), pp.505-517. ⟨10.1007/s00204-018-2345-2⟩. ⟨hal-02619117⟩
  • Normand Podechard, Simon Ducheix, Arnaud Polizzi, Frédéric Lasserre, Alexandra Montagner, et al.. Dual extraction of mRNA and lipids from a single biological sample. Scientific Reports, Nature Publishing Group, 2018, 8 (1), pp.7019. ⟨10.1038/s41598-018-25332-9⟩. ⟨hal-01794296⟩
  • Céline Lukowicz, Sandrine Ellero - Simatos, Marion Regnier, Arnaud Polizzi, Frédéric Lasserre, et al.. Metabolic effects of a chronic dietary exposure to a low-dose oesticide cocktail in mice: Sexual dimorphism and role of the constitutive androstane receptor. Environmental Health Perspectives, National Institute of Environmental Health Sciences, 2018, 126 (6), 18 p. ⟨10.1289/EHP2877⟩. ⟨hal-02624889⟩
  • Laure Monteillet, Monika Gjorgjieva, Marine Silva, Vincent Verzieux, Linda Imikirene, et al.. Intracellular lipids are an independent cause of liver injury and chronic kidney disease in non alcoholic fatty liver disease-like context. Molecular metabolism, Elsevier, 2018, 16, pp.100-115. ⟨10.1016/j.molmet.2018.07.006⟩. ⟨inserm-02339561⟩
  • Kalina Duszka, Sandrine Ellero-Simatos, Ghim Siong Ow, Marianne Defernez, Eeswari Paramalingam, et al.. Complementary intestinal mucosa and microbiota responses to caloric restriction. Scientific Reports, Nature Publishing Group, 2018, 8, ⟨10.1038/s41598-018-29815-7⟩. ⟨hal-02621482⟩
  • Hervé Guillou, Vincent Scao, Sébastien Nomade. 40 Ar/ 39 Ar age of cryptochron C2r.2r-1 as recorded in a lava sequence within the Ko'olau volcano (Hawaii, USA). Quaternary Geochronology, Elsevier, 2018, 43, pp.91 - 101. ⟨10.1016/j.quageo.2017.10.005⟩. ⟨hal-01806763⟩
  • Marion Regnier, Pascal Gourbeyre, Philippe Pinton, Scott Napper, Joëlle Laffitte, et al.. Identification of signaling pathways targeted by the food contaminant FB1: Transcriptome and kinome analysis of samples from pig liver and intestine. Molecular Nutrition and Food Research, Wiley-VCH Verlag, 2017, in press (12), 42 p. ⟨10.1002/mnfr.201700433⟩. ⟨hal-01606651⟩
  • Elizabeth R. Cattaneo, Eduardo Prieto, Maria B. Garcia-Fabiani, Mauro A. Montanaro, Hervé Guillou, et al.. Glycerol-3-phosphate acyltransferase 2 expression modulates cell roughness and membrane permeability: An atomic force microscopy study. PLoS ONE, Public Library of Science, 2017, 12 (12), 18 p. ⟨10.1371/journal.pone.0189031⟩. ⟨hal-02622165⟩
  • P. Morigny, M. Houssier, E. Mouisel, A. Mairal, S. Caspar-Bauguil, et al.. Type 2 diabetes prevention through hormone sensitive lipase inhibition: elongase ELOVL6 at the center of attention. Diabetologia, Springer Verlag, 2017, 60, pp.S249. ⟨hal-02624062⟩
  • Maeva Guillaume, Sandra Handgraaf, Aurelie J Fabre, Isabelle Raymond-Letron, Elodie Riant, et al.. Selective activation of estrogen receptor alpha activation function-1 is sufficient to prevent obesity, steatosis, and insulin resistance in mouse. American Journal of Pathology, American Society for Investigative Pathology, 2017, 187 (6), pp.1273-1287. ⟨10.1016/j.ajpath.2017.02.013⟩. ⟨hal-01603827⟩
  • Simon Ducheix, Alexandra Montagner, Arnaud Polizzi, Frédéric Lasserre, Marion Regnier, et al.. Dietary oleic acid regulates hepatic lipogenesis through a liver X receptor-dependent signaling. PLoS ONE, Public Library of Science, 2017, 12 (7), ⟨10.1371/journal.pone.0181393⟩. ⟨hal-01606929⟩
  • Marion Regnier, Arnaud Polizzi, Yannick Lippi, Edwin Fouche, Géraldine Michel, et al.. Insights into the role of hepatocyte PPARα activity in response to fasting. Molecular and Cellular Endocrinology, Elsevier, 2017, in press, ⟨10.1016/j.mce.2017.07.035⟩. ⟨hal-01605514⟩
  • Lucie Popineau, Lucille Morzyglod, Nadege Carre, Michele Cauzac, Pascale Bossard, et al.. Novel Grb14-Mediated Cross Talk between Insulin and p62/Nrf2 Pathways Regulates Liver Lipogenesis and Selective Insulin Resistance. Molecular and Cellular Biology, American Society for Microbiology, 2016, 36 (16), pp.2168 - 2181. ⟨10.1128/MCB.00170-16⟩. ⟨hal-01602453⟩
  • Claire Laurens, Virginie Bourlier, Aline Mairal, Katie Louche, Pierre-Marie Badin, et al.. Perilipin 5 fine-tunes lipid oxidation to metabolic demand and protects against lipotoxicity in skeletal muscle. Scientific Reports, Nature Publishing Group, 2016, 6, ⟨10.1038/srep38310⟩. ⟨hal-01605047⟩
  • Sandrine P. Claus, Hervé Guillou, Sandrine Ellero - Simatos. The gut microbiota: a major player in the toxicity of environmental pollutants?. npj Biofilms and Microbiomes, [London?]: Springer Nature published in partnership with Nanyang Technological University, 2016, 2, ⟨10.1038/npjbiofilms.2016.3⟩. ⟨hal-01602371⟩
  • Laura Norton, Yvonne Lindsay, Arnaud Deladeriere, Tamara Chessa, Hervé Guillou, et al.. Localizing the lipid products of PI3Kγ in neutrophils. Advances in Biological Regulation, 2016, 60, pp.36-45. ⟨10.1016/j.jbior.2015.10.005⟩. ⟨hal-01602482⟩
  • Virginie Rizzati, O. Briand, Hervé Guillou, Laurence Gamet Payrastre. Effects of pesticide mixtures in human and animal models: an update of the recent literature. Chemico-Biological Interactions, Elsevier, 2016, 254, pp.231-246. ⟨10.1016/j.cbi.2016.06.003⟩. ⟨hal-02637756⟩
  • Sylvie Casteras, Aya Abdul-Wahed, Maud Soty, Fanny Vulin, Hervé Guillou, et al.. The suppression of hepatic glucose production improves metabolism and insulin sensitivity in subcutaneous adipose tissue in mice. Diabetologia, Springer Verlag, 2016, 59 (12), pp.2645-2653. ⟨10.1007/s00125-016-4097-y⟩. ⟨hal-01606287⟩
  • Alexandra Montagner, Arnaud Polizzi, Edwin Fouché, Simon Ducheix, Yannick Lippi, et al.. Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD. Gut, BMJ Publishing Group, 2016, 65 (7), pp.1202-1214. ⟨10.1136/gutjnl-2015-310798⟩. ⟨inserm-02339685⟩
  • Gianpaolo Rando, Chek Kun Tan, Nourhène Khaled, Alexandra Montagner, Nicolas Leuenberger, et al.. Glucocorticoid receptor-PPAR alpha axis in fetal mouse liver prepares neonates for milk lipid catabolism. eLife, eLife Sciences Publication, 2016, 5, 31 p. ⟨10.7554/eLife.11853⟩. ⟨hal-01602433⟩
  • Arnaud Polizzi, Edwin Fouche, Simon Ducheix, Frédéric Lasserre, Alice Marmugi, et al.. Hepatic fasting-induced PPAR alpha activity does not depend on essential fatty acids. International Journal of Molecular Sciences, MDPI, 2016, 17 (10), pp.1624. ⟨10.3390/ijms17101624⟩. ⟨hal-01476503⟩
  • Alexandra Montagner, Agata Korecka, Arnaud Polizzi, Yannick Lippi, Yuna Blum, et al.. Hepatic circadian clock oscillators and nuclear receptors integrate microbiome-derived signals. Scientific Reports, Nature Publishing Group, 2016, 6 (1), pp.1-14. ⟨10.1038/srep20127⟩. ⟨hal-01482816⟩
  • Kalina Duszka, Alexandre Picard, Sandrine Ellero - Simatos, Jiapeng Chen, Marianne Defernez, et al.. Intestinal PPAR gamma signalling is required for sympathetic nervous system activation in response to caloric restriction. Scientific Reports, Nature Publishing Group, 2016, 6, ⟨10.1038/srep36937⟩. ⟨hal-01606898⟩
  • Nguan Soon Tan, Manuel Vázquez-Carrera, Alexandra Montagner, Ming Keat Sng, Hervé Guillou, et al.. Transcriptional control of physiological and pathological processes by the nuclear receptor PPAR beta/delta. Progress in Lipid Research, Elsevier, 2016, 64, pp.98-122. ⟨10.1016/j.plipres.2016.09.001⟩. ⟨hal-01594607⟩
  • Nicolas Loiseau, Arnaud Polizzi, Aude Dupuy, Nicole Therville, Mirindra Rakotonirainy, et al.. New insights into the organ-specific adverse effects of fumonisin B1: comparison between lung and liver. Archives of Toxicology, Springer Verlag, 2015, 89 (9), pp.1619-1629. ⟨10.1007/s00204-014-1323-6⟩. ⟨hal-02633945⟩
  • Marie Tremblay Franco, Chiara Zerbinati, Antonio Pacelli, Giuseppina Palmaccio, Carla Lubrano, et al.. Effect of obesity and metabolic syndrome on plasma oxysterols and fatty acids in human. Steroids, Elsevier, 2015, 99 (Part B), pp.287-292. ⟨10.1016/j.steroids.2015.03.019⟩. ⟨hal-02639945⟩
  • Pierre-François Roux, Simon Boitard, Anne Blum, Brian Parks, Alexandra Montagner, et al.. Combined QTL and selective sweep mappings with coding SNP annotation and cis-eQTL analysis revealed PARK2 and JAG2 as new candidate genes for adiposity regulation.. G3, Genetics Society of America, 2015, 5, pp.517-529. ⟨10.1534/g3.115.016865⟩. ⟨hal-01194040⟩
  • Thomas Gobbetti, Simon Ducheix, Pauline Le Faouder, T. Perez, Teresa Pérez-Berezo, et al.. Protective effects of n-6 fatty acids-enriched diet on intestinal ischaemia/reperfusion injury involve lipoxin A4 and its receptor. British Journal of Pharmacology, Wiley, 2015, 172 (3), pp.910-923. ⟨10.1111/bph.12957⟩. ⟨hal-01601458⟩
  • Alice Marmugi, Frederic Lasserre, Diane Beuzelin, Simon Ducheix, Laurence Huc, et al.. Adverse effects of long-term exposure to bisphenol A during adulthood leading to hyperglycaemia and hypercholesterolemia in mice. Toxicology, Elsevier, 2014, 325, pp.133-143. ⟨10.1016/j.tox.2014.08.006⟩. ⟨hal-02641668⟩
  • Ali Seyrek, Tuncer Demir, Rob Westaway, Hervé Guillou, Stéphane Scaillet. Corrigendum to “The kinematics of central-southern Turkey and northwest Syria revisited” [Tectonophysics 618 (2014) 35–66]: Refers to : Ali Seyrek, Tuncer Demir, Rob Westaway, Hervé Guillou, Stéphane Scaillet, Tom S. White, David R. BridglandThe kinematics of central-southern Turkey and northwest Syria revisitedTectonophysics, Volume 618, 31 March 2014, Pages 35-66. Tectonophysics, Elsevier, 2014, 630, pp.319-320. ⟨10.1016/j.tecto.2014.07.014⟩. ⟨insu-01095082⟩
  • N. Ramamonjisoa, H. Ratiney, E. Mutel, Hervé Guillou, G. Mithieux, et al.. In vivo hepatic lipid quantification using MRS at 7 Tesla in a mouse model of glycogen storage disease type 1a. Journal of Lipid Research, American Society for Biochemistry and Molecular Biology, 2013, 54 (7), pp.2010-2022. ⟨10.1194/jlr.D033399⟩. ⟨hal-00847703⟩
  • Simon Ducheix, Alexandra Montagner, Vassilia Theodorou, Laurent Ferrier, Hervé Guillou. The liver X receptor: A master regulator of the gut-liver axis and a target for non alcoholic fatty liver disease. Biochemical Pharmacology, Elsevier, 2013, 86 (1), pp.96 - 105. ⟨10.1016/j.bcp.2013.03.016⟩. ⟨hal-02646839⟩
  • Simon Ducheix, Alexandra Montagner, Arnaud Polizzi, Frédéric Lasserre, Alice Marmugi, et al.. Essential fatty acids deficiency promotes lipogenic gene expression and hepatic steatosis through the liver X receptor.. Journal of Hepatology, Elsevier, 2013, 58 (5), pp.984-92. ⟨10.1016/j.jhep.2013.01.006⟩. ⟨inserm-00872314⟩
  • Simon Ducheix, Normand Podechard, Frédéric Lasserre, Arnaud Polizzi, Aurélien Pommier, et al.. A systems biology approach to the hepatic role of the oxysterol receptor LXR in the regulation of lipogenesis highlights a cross-talk with PPARα.. Biochimie, Elsevier, 2013, 95 (3), pp.556-67. ⟨10.1016/j.biochi.2012.09.028⟩. ⟨inserm-00872582⟩
  • Sabine Suire Sabine, Charlotte Lécureuil, Karen Anderson E, George Damoulakis George, Izabella Niewczas Izabella, et al.. GPCR activation of Ras and PI3Kc in neutrophils depends on PLCb2/b3 and the RasGEF RasGRP4. EMBO Journal, EMBO Press, 2012, 31 (14), pp.3118-3129. ⟨10.1038/emboj.2012.167⟩. ⟨hal-00776864⟩
  • . Benhamed F, Denechaud Pd, Robichon C, Moldes M, Girard J, . Lemoine M, Serfaty L, Housset C, Capeau J,, Justine Bertrand-Michel, Vlad Ratziu, Hervé Guillou, et al.. The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans. Journal of Clinical Investigation, American Society for Clinical Investigation, 2012, 122 (6), pp.2176-94. ⟨10.1172/JCI41636⟩. ⟨hal-02649316⟩
  • Radina Kostadinova, Alexandra Montagner, Erwan Gouranton, Sébastien Fleury, Hervé Guillou, et al.. GW501516-activated PPARbeta/delta promotes liver fibrosis via p38-JNK MAPK-induced hepatic stellate cell proliferation.. Cell & Bioscience, BioMed Central, 2012, 2 (1), pp.34. ⟨10.1186/2045-3701-2-34⟩. ⟨inserm-00763884⟩
  • Alice Marmugi, Simon Ducheix, Frederic Lasserre, Arnaud Polizzi, Alain Paris, et al.. Low Doses of Bisphenol A Induce Gene Expression Related to Lipid Synthesis and Trigger Triglyceride Accumulation in Adult Mouse Liver. Hepatology, Wiley-Blackwell, 2012, 55 (2), pp.395-407. ⟨10.1002/hep.24685⟩. ⟨hal-01019497⟩
  • Damir Zadravec, Petr Tvrdik, Hervé Guillou, Rilchard Haslam, Tsutomu Kobayash, et al.. ELOVL2 controls the level of n-6 28:5 and 30:5 fatty acids in testis, a prerequisite for male fertility and spermmaturation in mice. Journal of Lipid Research, American Society for Biochemistry and Molecular Biology, 2011, 52 (2), pp.245-255. ⟨10.1194/jlr.M011346⟩. ⟨hal-01137032⟩
  • Suhasini Kulkarni, Cassian Sitaru, Zoltan Jakus, Karen E. Anderson, George Damoulakis, et al.. PI3K beta Plays a Critical Role in Neutrophil Activation by Immune Complexes. Science Signaling, American Association for the Advancement of Science, 2011, 4 (168), pp.ra23. ⟨10.1126/scisignal.2001617⟩. ⟨hal-02649985⟩
  • Magali Vignault-Foucaud, Zeina Soayfane, Cécile Menez-Berlioz, Justine Bertrand-Michel, Pascal Guy, et al.. P-glycoprotein Dysfunction Contributes to Hepatic Steatosis and Obesity in Mice. PLoS ONE, Public Library of Science, 2011, 6 (9), ⟨10.1371/journal.pone.0023614⟩. ⟨hal-02650319⟩
  • Isabelle Olivier, Vassilia Théodorou, Philippe Valet, Isabelle Castan-Laurell, Hervé Guillou, et al.. Is Crohn's creeping fat an adipose tissue?. Inflammatory Bowel Diseases, Lippincott, Williams & Wilkins, 2011, 17 (3), pp.747-57. ⟨10.1002/ibd.21413⟩. ⟨inserm-00617823⟩
  • Magali Foucaud-Vignault, Zeina Soayfane, Cécile Menez-Berlioz, Justine Bertrand-Michel, Pascal Martin, et al.. P-glycoprotein Dysfunction Contributes to HepaticSteatosis and Obesity in Mice. PLoS ONE, Public Library of Science, 2011, 6 (9), pp.e23614. ⟨hal-01137178⟩
  • Simon Ducheix, J.M.A. Lobaccaro, Pascal Martin, Hervé Guillou. Liver X Receptor: an oxysterol sensor and a major playerin the control of lipogenesis. Chemistry and Physics of Lipids, Elsevier, 2011, 164 (6), pp.500-14. ⟨10.1016/j.chemphyslip.2011.06.004⟩. ⟨hal-02651993⟩
  • Helen E. Craig, John Coadwell, Hervé Guillou, Sonja Vermeren. ARAP3 binding to phosphatidylinositol-(3,4,5)-trisphosphate depends on N-terminal tandem PH domains and adjacent sequences. Cellular Signalling, Elsevier, 2010, 22 (2), pp.257-264. ⟨10.1016/j.cellsig.2009.09.025⟩. ⟨hal-02662592⟩
  • Damir Zadravec, Annelie Brolinson, Rachel M. Fisher, Claes Carneheim, Robert I. Csikasz, et al.. Ablation of the very-long-chain fatty acid elongase ELOVL3 in mice leads to constrained lipid storage and resistance to diet-induced obesity. FASEB Journal, Federation of American Society of Experimental Biology, 2010, 24 (11), pp.4366 - 4377. ⟨10.1096/fj.09-152298⟩. ⟨hal-02662422⟩
  • Pierre Blavy, Florence Gondret, Hervé Guillou, Sandrine Lagarrigue, P.G.P. Martin, et al.. A minimal model for hepatic fatty acid balance during fasting: Application to PPAR alpha-deficient mice. Journal of Theoretical Biology, Elsevier, 2009, 261 (2), pp.266. ⟨10.1016/j.jtbi.2009.07.025⟩. ⟨hal-00559147⟩
  • Alexandre Eveillard, Frederic Lasserre, M de Tayrac, Arnaud Polizzi, S Claus, et al.. Identification of potential mechanisms of toxicity after di-(2-ethylhexyl)-phthalate (DEHP) adult exposure in the liver using a systems biology approach. Toxicology and Applied Pharmacology, Elsevier, 2009, 236 (3), pp.282-292. ⟨10.1016/j.taap.2009.02.008⟩. ⟨hal-02662270⟩
  • Hervé Guillou, Pg Martin, Thierry Pineau. Transcriptional regulation of hepatic fatty acid metabolism. Sub-cellular biochemistry, 2008, 49, pp.3-47. ⟨hal-02653666⟩
  • Hervé Guillou, Vincent Rioux, Daniel Catheline, Jean-Noel Thibault, Monique Bouriel, et al.. Conversion of hexadecanoic acid to hexadecenoic acid by rat delta 6-desaturase. Journal of Lipid Research, American Society for Biochemistry and Molecular Biology, 2003, 44 (3), pp.450-454. ⟨10.1194/jlr.C200019-JLR200⟩. ⟨hal-02678861⟩
  • Sabine d'Andrea, Hervé Guillou, S. Jan, Daniel Catheline, Jean-Noel Thibault, et al.. The same rat delta 6-desaturase not only acts on 18- but also on 24-carbon fatty acids in very-long-chain polyunsaturated fatty acid biosynthesis. Biochemical Journal, Portland Press, 2002, 364, pp.49-55. ⟨hal-02669429⟩
  • Hervé Guillou, Guy Miranda, J.P. Pelissier. Hydrolysis of beta-casein by gastric proteases. 1. Comparison of proteolytic action of bovine chymosin and pepsin A. International Journal of Peptide and Protein Research, 1991, 37, pp.494-501. ⟨hal-02708181⟩
  • Hervé Guillou, Guy Miranda, J.P. Pelissier. Analyse quantitative des caseines dans le lait de vache par chromatographie liquide rapide d'echange d'ions (FPLC). Lait, Elsevier, 1987, 67, pp.135-148. ⟨hal-02719777⟩
  • Hervé Guillou, Guy Miranda, J.P. Pelissier. Analyse quantitative des caseines dans le lait de vache par chromatographie liquide rapide d'echanges d'ions (FPLC). Lait, Elsevier, 1987, 67 (2), pp.135-148. ⟨hal-02721649⟩
  • Hervé Guillou, J.P. Pelissier, R. Grappin. Methodes de dosage des proteines du lait de vache. Lait, Elsevier, 1986, 66, pp.143-175. ⟨hal-02718097⟩

Conference papers39 documents

  • Blandine Tramunt, Sarra Smati, Naia Grandgeorge, Anne Fougerat, Maxime Guillaume, et al.. Sex dimorphic role of estrogen receptor a in physiological regulation of hepatic metabolism. 55. Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), Sep 2019, Barcelona, Spain. 1 p. ⟨hal-02734566⟩
  • Hanna Ilchmann-Diounou, Maïwenn Olier, Corinne Lencina, Ambre Riba, Sharon Barretto, et al.. Early life stress induces type 2 diabetes-like features in ageing mice. NeuroGASTRO 2019 Congress, Sep 2019, Lisbon, Portugal. 1 p. ⟨hal-02736934⟩
  • Sarra Smati, Arnaud Polizzi, Marion Regnier, Alain Marrot, C. Luzowicz, et al.. Influence of gender on progression of liver metabolic diseases in response to different nutritional challenges. 54. Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), European Association for the Study of Diabetes (EASD). GBR., Oct 2018, Berlin, Germany. pp.1. ⟨hal-02735253⟩
  • Céline Lukowicz, Marion Regnier, Frédéric Lasserre, Arnaud Polizzi, Alexandra Montagner, et al.. Constitutive Androstane Receptor deficiency leads to sexually dimorphic metabolic disorders in aging. 54. Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), European Association for the Study of Diabetes (EASD). GBR., Oct 2018, Berlin, France. pp.1. ⟨hal-02735254⟩
  • Catherine Postic, Alison Iroz, Alexandra Montagner, Fadila Benhamed, Arnaud Polizzi, et al.. Hepatokines in metabolic disease: novel insights into FGF21 regulation by glucose. 52. Annual Scientific Meeting of the European Society for Clinical Investigation “Precision medicine for healthy ageing”, May 2018, Barcelone, Spain. pp.1. ⟨hal-02734271⟩
  • Laure Monteillet, Monika Gjorgjieva, Marine Silva, Vincent Verzieux, Hervé Guillou, et al.. Intracellular lipids: an independent cause of liver injury and chronic kidney disease in non-alcoholic fatty liver disease-like context. G2L2, Oct 2018, Genève, Switzerland. ⟨inserm-02388687⟩
  • Hanna Ilchmann, Maiwenn Olier, Corinne Lencina, Sandrine Ellero - Simatos, Ambre Riba, et al.. Early life stress induces type 2 diabetes at adulthood in male mice. 10. International Meeting of Pediatric Endocrinology, Sep 2017, Washington, United States. ⟨hal-01603069⟩
  • Hanna Ilchmann, Corinne Lencina, Sandrine Ellero - Simatos, Ambre Riba, Cherryl Harkat, et al.. Chronic maternal separation in mice impaired immuno-metabolism in older offspring on standard diet. The Neonatal Window of Opportunity, Early Priming for Life, Herrenhausen Conference, Dec 2016, Hanovre, Germany. ⟨hal-01608144⟩
  • Maeva Guillaume, Sandra Handgraaf, Isabelle Raymond-Letron, Aude Fabre, Elodie Riant, et al.. Specific modulation of hepatic estrogen receptor alpha prevents fatty liver but also obesity and insulin resistance induced by a high fat diet in mice. 50th International Liver Congress of the European-Association-for-the-Study-of-the-Liver, European Association for the Study of the Liver (EASL). Genève, CHE., Apr 2015, Vienne, Austria. 1 p. ⟨hal-02743029⟩
  • Pauline Morigny, Marianne Houssier, Sylvie Caspar Bauguil, Diane Beuzelin, Aline Mairal, et al.. Partial inhibition of hormone-sensitive lipase improves insulin sensitivity by induction of de novo lipogenesis and elongase ELOVL6 in human adipocytes. 51. Annual Meeting of the European Association for the Study of Diabetes (EASD), European Association for the Study of Diabetes (EASD). Düsseldorf, GBR., Sep 2015, Stockholm, Sweden. 2 p. ⟨hal-02744175⟩
  • Beatrice Roques, Marlène Lacroix, Nabila Moussaoui, Julien Leghait, Sylvie Puel, et al.. Contribution of the nuclear receptors PXR and CAR to gene expression modulations induced by fipronil in rodent liver. 4th Health Food Symposium, Pôle Aliment Sécurité Sanitaire & Santé (PA3S)., 2012, Toulouse, France. ⟨hal-02802231⟩
  • Beatrice Roques, Marlène Lacroix, Nabila Moussaoui, Julien Leghait, Sylvie Puel, et al.. Contribution of the nuclear receptors PXR and CAR to gene expression modulations induced by fipronil in rodent liver. 12th International Congress of the European Association for Veterinary Pharmacology and Toxicology (EAVPT), Jul 2012, Noordwijkerhout, Netherlands. pp.1-182. ⟨hal-02744689⟩
  • Damir Zadravec, Petr Tvrdik, Hervé Guillou, Richard Haslam, Tsutomu Kobayashi, et al.. ELOVL2 controls the level of n-628:5 and 30:5 fatty acids in testis, a prerequisite for male fertility and sperm maturation in mice. 52. International Conference on the Bioscience of Lipids : Expanding the Horizons of Lipidomics, International Conference on the Bioscience of Lipids (ICBL). INT., Aug 2011, Varsovie, Poland. ⟨10.1016/j.chemphyslip.2011.05.035⟩. ⟨hal-02747851⟩
  • Hervé Guillou. An xosysterol sensor and a master regulator of lipogenesis. ENOR meeting, Saisissez le nom du laboratoire, du service ou du département., Ville service., Sep 2011, Rome, Italy. ⟨hal-02802433⟩
  • Hervé Guillou. Oxysterol signaling in fatty acid metabolism. INSERM U915, L'institut du Thorax, Saisissez le nom du laboratoire, du service ou du département., Ville service., Jan 2011, Nantes, France. ⟨hal-02802818⟩
  • Hervé Guillou. Regulation of hepatic lipid metabolism: effect of dietary fatty acids and effect of Bisphenol A. Centre de Génomique Integrative de Lausanne, Centre de Génomique Integrative de Lausanne., Feb 2011, Lausanne, Switzerland. ⟨hal-02802819⟩
  • Hervé Guillou. Rôle de LXR dans le métabolisme des acides gras. Institut Cochin, Institut Cochin. Dr Catherine Postic, Ville service, FRA., Mar 2011, Cochin, France. ⟨hal-02802820⟩
  • Hervé Guillou. Role of LXR in hepatic fatty acid homeostasis revealed through a nutrigenomic approach. Journées des récepteurs nucléaires, Muséum National d’Histoire Naturelle (MNHN). Saisissez le nom du laboratoire, du service ou du département., Paris, FRA., Mar 2011, Paris, France. ⟨hal-02802823⟩
  • Hervé Guillou. Regulation of hepatic lipid metabolism: effect of dietary fatty acids and effect of Bisphenol A.. ENS Lyon, Ecole Normale Supérieure (ENS). Dr Hugo Aguilaniu, Lyon, FRA., Apr 2011, Lyon, France. ⟨hal-02803044⟩
  • . Poupeau A., Rayah-Benhamed F., Dentin R., Hervé Guillou, . Girard J., Postic C.. L’expression d’une forme active de ChREBP conduit à la réinduction de la lipogenèse dans un modèle animal de déficience en LXR et SREBP-1c. 69èmes journées de l'Agence Française d’Etude du Foie, Saisissez le nom du laboratoire, du service ou du département., Ville service., Sep 2011, Paris, France. ⟨hal-02804525⟩
  • Simon Ducheix, F Rayah-Benhamed, Alexandra Montagner, Arnaud Polizzi, Frederic Lasserre, et al.. Régulation du Liver X Receptor par le fructose et développement de la stéatose hépatique. 9. Journées Francophones de Nutrition (JFN), Ville service., Dec 2011, Reims, France. ⟨hal-02805683⟩
  • Yuna Blum, Olivier Demeure, Colette Désert, Hervé Guillou, J Bertrand-Michel, et al.. Integrating QTL controlling fatness, lipid metabolites and gene expressions to genetically dissect the adiposity complex trait in a meat chicken cross. 62. Annual Meeting of the European Association for Animal Production (EAAP), Aug 2011, Stavanger, Norway. ⟨hal-02748764⟩
  • Hervé Guillou. Nuclear receptors in the transcriptional control of hepatic fatty acid metabolism. The Wenner-Gren Institute, University of Stockholm, Sep 2009, Stockholm, Sweden. pp.Inconnu. ⟨hal-02813403⟩
  • Pierre Blavy, Florence Gondret, Hervé Guillou, Sandrine Lagarrigue, Pascal Martin, et al.. A minimal and dynamic model for fatty acid metabolism in mouse liver. Journées Ouvertes de Biologie, Informatique et Mathématique (JOBIM), Jun 2008, Lille (FR), France. ⟨hal-00729742⟩
  • Pierre Blavy, Florence Gondret, Hervé Guillou, Sandrine Lagarrigue, Pascal Martin, et al.. A minimal and dynamic model for fatty acid metabolism in mouse liver. Journées Ouvertes de Biologie, Informatique et Mathématique (JOBIM), Jun 2008, Lille, France. ⟨hal-02756716⟩
  • Pierre Blavy, Florence Gondret, Hervé Guillou, Sandrine Lagarrigue, Pascal Martin, et al.. A minimal and dynamical model for fatty acid metabolism in mouse liver. Journées Ouvertes Biologie Informatique Mathématiques, 2008, Lille, France. pp.Inconnu. ⟨hal-02817340⟩
  • Pascal Martin, Frederic Lasserre, Hervé Guillou, R Barnouin, S Dejean, et al.. PPARa remplit-il véritablement la fonction de senseur nutritionnel vis-à-vis des acides gras alimentaires ? Une étude comparée de signatures transcriptomique et lipidomique. Journée GERLI de lipidomique, 2005, Toulouse, France. pp.Inconnu. ⟨hal-02829883⟩
  • Pgp Martin, R Barnouin, Frederic Lasserre, Hervé Guillou, Michela Cantiello, et al.. A kinetic view of coordinate modulations of gene expression and metabolism in wild-type and PPARa-/- mice during fasting. Cycles de conferences de l'IFR31, 2005, Toulouse, France. pp.Inconnu. ⟨hal-02832532⟩
  • Pascal Martin, Hervé Guillou, Frederic Lasserre, S Dejean, P Legrand, et al.. Empreintes transcriptionnelles de lipides alimentaires sur modèles souris. Analyse intégrée de signatures variées GENOTOUL, 2005, Toulouse, France. pp.Inconnu. ⟨hal-02825872⟩
  • R Barnouin, Frederic Lasserre, Michela Cantiello, Hervé Guillou, Thierry Pineau, et al.. A kinetic view of coordinate modulations of gene expression and metabolism in wild-type and PPARa-/- mice during fasting. Gene signature symposia, 2005, Paris, France. pp.Inconnu. ⟨hal-02828236⟩
  • Pascal Martin, Frederic Lasserre, Hervé Guillou, R Barnouin, S Dejean, et al.. Influence des acides gras alimentaires sur les voies de signalisation des récepteurs nucléaires : une étude comparée de signatures transcriptomique et lipidomique. Journées Scientifiques du GIS « PA-3S », 2005, Boussens, France. pp.Inconnu. ⟨hal-02834051⟩
  • Pascal Martin, Hervé Guillou, Frederic Lasserre, A Paris, S Dejean, et al.. Characterization of hepatic effects induced by food lipids from the analysis of their biological signatures in mice. Journée d’animation du Département d’Alimentation Humaine de l’INRA, 2004, Paris, France. pp.Inconnu. ⟨hal-02826237⟩
  • Pascal Martin, Hervé Guillou, Frederic Lasserre, S Dejean, P Legrand, et al.. Caractérisation des effets hépatiques induits par les lipides alimentaires par analyse de leurs signatures biologiques chez la souris. Journée d’animation scientifique de l’IFR30, 2004, Toulouse, France. pp.Inconnu. ⟨hal-02825956⟩
  • R Barnouin, Frederic Lasserre, M Cantielo, Hervé Guillou, Thierry Pineau, et al.. A kinetic view of coordinate modulations of gene expression and metabolism in wild type and PPARa-/- mice during fasting. Conference of the Paul Hamel Institute / New developements in the metabolic syndrome, 2004, Monaco, France. pp.Inconnu. ⟨hal-02828078⟩
  • Pascal Martin, Frederic Lasserre, Hervé Guillou, R Barnouin, S Dejean, et al.. Biological effects of nutrients : what interdisciplinary strategies to grasp and analyze complex signatures. Journée d’animation du Département d’Alimentation Humaine de l’INRA, 2004, Paris, France. pp.Inconnu. ⟨hal-02833182⟩
  • Pascal Martin, Frederic Lasserre, Hervé Guillou, R Barnouin, S Dejean, et al.. Is PPARa a true nutritional sensor for dietary fatty acids: a coordinate transcriptomic and lipidomic study. Journée d’animation scientifique de l’IFR31, 2004, Toulouse, France. pp.Inconnu. ⟨hal-02829897⟩
  • Pascal Martin, Hervé Guillou, Frederic Lasserre, Cécile Calléja, S Jan, et al.. Effects of dietary fatty acids on the expression of an array of class II nuclear receptor target genes. Inconnu, 2003, pp.Inconnu. ⟨hal-02833157⟩
  • Hervé Guillou, Pascal Martin, S Jan, Sabine d'Andrea, Alain Roulet, et al.. Regulation of hepatic desaturases by PPAR alpha. Inconnu, 2003, pp.Inconnu. ⟨hal-02832865⟩
  • Benedicte Savalle, P. Garnier, Guy Miranda, Hervé Guillou, J.P. Pelissier. Modelisation de la digestion gastrique des proteines du lait. Journee d'automne d'information scientifique, Oct 1987, Jouy-en-Josas, France. ⟨hal-02783241⟩

Books1 document

  • Hervé Guillou, Bertil Sylvander. La situation de la filière biologique en 1997. INRA-ESR, 54 p., 1997, 2-7380-0808-9. ⟨hal-02837070⟩

Book sections1 document

  • Hervé Guillou, Pgp Martin, Thierry Pineau. Transcriptional regulation of hepatic fatty acid metabolism. Subcellular Biochemistry: Lipids in Health and Disease, Springer, 2009. ⟨hal-02815951⟩

Preprints, Working Papers, ...1 document

  • Hervé Guillou, Bertil Sylvander. Les relations entre les transformateurs de produits biologiques et la grande distribution : stratégies d'acteurs. 1997. ⟨hal-02836285⟩

Reports1 document

  • Nicolas Loiseau, Arnaud Polizzi, Frédéric Lasserre, Hervé Guillou, Marlène Lacroix, et al.. Preuve de concept ARCHIPL: Bilan de l'évaluation in vitro de la rétention du déoxynivalénol par des parois de levure modifiées par hémisynthèse. 2014. ⟨hal-02801787⟩

Theses1 document

  • Hervé Guillou. Hydrolyse de la caseine beta par les proteases gastriques. Sciences du Vivant [q-bio]. Université Paris Sud - Paris 11, 1988. Français. ⟨tel-02857325⟩