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Hersen Pascal

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Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability

Fabien Duveau , Céline Cordier , Lionel Chiron , Matthias Lebec , Sylvain Pouzet
Article dans une revue hal-04288775v1
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Optogenetic control of beta-carotene bioproduction in yeast across multiple lab-scales

Sylvain Pouzet , Jessica Cruz-Ramón , Matthias Le Bec , Céline Cordier , Alvaro Banderas
Frontiers in Bioengineering and Biotechnology, 2023, 11, pp.1085268. ⟨10.3389/fbioe.2023.1085268⟩
Article dans une revue hal-04247146v1
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CyberSco.Py an open-source software for event-based, conditional microscopy

Lionel Chiron , Matthias Le Bec , Céline Cordier , Sylvain Pouzet , Dimitrije Milunov
Scientific Reports, 2022, 12 (1), pp.11579. ⟨10.1038/s41598-022-15207-5⟩
Article dans une revue hal-03761554v1
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Observing Nutrient Gradients, Gene Expression and Growth Variation Using the "Yeast Machine" Microfluidic Device

Zoran Marinkovic , Clément Vulin , Mislav Acman , Xiaohu Song , Jean Di Meglio
Bio-protocol , 2020, 10 (13), ⟨10.21769/BioProtoc.3668⟩
Article dans une revue hal-03083179v1
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The Promise of Optogenetics for Bioproduction: Dynamic Control Strategies and Scale-Up Instruments

Sylvain Pouzet , Alvaro Banderas , Matthias Le Bec , Thomas Lautier , Gilles Truan
Bioengineering, 2020, 7 (4), pp.151. ⟨10.3390/bioengineering7040151⟩
Article dans une revue hal-03083199v1
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Rational programming of history-dependent logic in cellular populations

Ana Zúñiga , Sarah Guiziou , Pauline Mayonove , Zachary Ben Meriem , Miguel Camacho
Nature Communications, 2020, 11 (1), pp.4758. ⟨10.1038/s41467-020-18455-z⟩
Article dans une revue inserm-02952457v1
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Autonomous and Assisted Control for Synthetic Microbiology

Alvaro Banderas , Matthias Le Bec , Céline Cordier , Pascal Hersen
International Journal of Molecular Sciences, 2020, 21 (23), pp.9223. ⟨10.3390/ijms21239223⟩
Article dans une revue hal-03083194v1
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A microfluidic device for inferring metabolic landscapes in yeast monolayer colonies

Zoran Marinkovic , Clément Vulin , Mislav Acman , Xiaohu Song , Jean-Marc Di Meglio
Article dans une revue hal-02331190v1

Enrichment of persisters enabled by a ß-lactam-induced filamentation method reveals their stochastic single-cell awakening

Etthel Windels , Zacchari Ben Meriem , Taiyeb Zahir , Kevin Verstrepen , Pascal Hersen
Communications Biology, 2019, 2 (1), pp.426. ⟨10.1038/s42003-019-0672-3⟩
Article dans une revue hal-03761734v1
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Hyperosmotic Stress Response Memory is Modulated by Gene Positioning in Yeast

Zacchari Ben Meriem , Yasmine Khalil , Pascal Hersen , Emmanuelle Fabre
Cells, 2019, 8 (6), pp.582. ⟨10.3390/cells8060582⟩
Article dans une revue hal-02331194v1
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Identification of individual cells from z-stacks of bright-field microscopy images

Jean-Baptiste Lugagne , Srajan Jain , Pierre Ivanovitch , Zacchary Ben Meriem , Clément Vulin
Scientific Reports, 2018, 8 (1), pp.11455. ⟨10.1038/s41598-018-29647-5⟩
Article dans une revue hal-01898065v1

Extracellular Vesicle Production Loaded with Nanoparticles and Drugs in a Trade-off between Loading, Yield and Purity: Towards a Personalized Drug Delivery System

Max Piffoux , Amanda Silva , Jean-Baptiste Lugagne , Pascal Hersen , Claire Wilhelm
Advanced Biosystems, 2017, 1 (5), pp.1700044. ⟨10.1002/adbi.201700044⟩
Article dans une revue hal-03761731v1
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Long-term tracking of budding yeast cells in brightfield microscopy: CellStar and the Evaluation Platform

Cristian Versari , Szymon Stoma , Kirill Batmanov , Artémis Llamosi , Filip Mroz
Journal of the Royal Society Interface, 2017, 14 (127), pp.32. ⟨10.1098/rsif.2016.0705⟩
Article dans une revue hal-01547623v1
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Balancing a genetic toggle switch by real-time feedback control and periodic forcing

Jean-Baptiste Lugagne , Sebastián Sosa Carrillo , Melanie Kirch , Agnes Köhler , Gregory Batt
Nature Communications, 2017, 8 (1), pp.1-8. ⟨10.1038/s41467-017-01498-0⟩
Article dans une revue hal-01666980v1

Long-range self-organization of cytoskeletal myosin II filament stacks

Shiqiong Hu , Kinjal Dasbiswas , Zhenhuan Guo , Yee-Han Tee , Visalatchi Thiagarajan
Nature Cell Biology, 2017, 19 (2), pp.133-141. ⟨10.1038/ncb3466⟩
Article dans une revue hal-03761727v1
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Assembly and Characterizations of Bifunctional Fluorescent and Magnetic Microneedles Displaying Length Tunability over One Decade

Jean-Baptiste Lugagne , Gwennhaël Brackx , Emek Seyrek , Sophie Nowak , Yann Sivry
Advanced Functional Materials, 2017, 27 (31), pp.1700362. ⟨10.1002/adfm.201700362⟩
Article dans une revue hal-02342490v1
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Out-of-equilibrium stationary states, percolation, and subcritical instabilities in a fully nonconservative system

Mathieu Génois , Pascal Hersen , Eric Bertin , Sylvain Courrech Du Pont , Guillaume Grégoire
Physical Review E , 2016, 94 (4), pp.042101. ⟨10.1103/physreve.94.042101⟩
Article dans une revue hal-02001608v3

What population reveals about individual cell identity: Single-cell parameter estimation of models of gene expression in yeast

Artémis Llamosi , Andres Gonzalez , Cristian Versari , Eugenio Cinquemani , Giancarlo Ferrari-Trecate
PLoS Computational Biology, 2016, 12 (2), pp.e1004706. ⟨10.1371/journal.pcbi.1004706⟩
Article dans une revue hal-01248298v1
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Age-Related Changes in Locomotor Performance Reveal a Similar Pattern for Caenorhabditis elegans, Mus domesticus, Canis familiaris, Equus caballus, and Homo sapiens

Adrien Marck , Geoffroy C.B. Berthelot , Vincent Foulonneau , Andy Marc , Juliana Antero
Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2016, 72 (4), pp.455-463. ⟨10.1093/gerona/glw136⟩
Article dans une revue hal-01792239v1

Structured illumination microscopy reveals focal adhesions are composed of linear subunits

Shiqiong Hu , Yee-Han Tee , Alexandre Kabla , Ronen Zaidel-Bar , Alexander Bershadsky
Cytoskeleton, 2015, 72 (5), pp.235-245. ⟨10.1002/cm.21223⟩
Article dans une revue hal-03761721v1
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Combining Spinach-tagged RNA and gene localization to image gene expression in live yeast

David Guet , Laura Burns , Suman Maji , Jérôme Boulanger , Pascal Hersen
Nature Communications, 2015, 6, pp.8882. ⟨10.1038/ncomms9882⟩
Article dans une revue hal-01725192v1

In vivo measurement of signaling cascade dynamics

Megan Mcclean , Pascal Hersen , Sharad Ramanathan
Cell Cycle, 2014, pp.373-376. ⟨10.4161/cc.8.3.7450⟩
Article dans une revue hal-03761747v1

High transcript levels of heat-shock genes are associated with shorter lifespan of Caenorhabditis elegans

X. Manière , A. Krisko , F.X. Pellay , J.-M. Di Meglio , Pascal Hersen
Experimental Gerontology, 2014, 60 (11), pp.12-17. ⟨10.1016/j.exger.2014.09.005⟩
Article dans une revue hal-03761717v1

Growing Yeast into Cylindrical Colonies

Clément Vulin , Jean-Marc Di Meglio , Ariel B. Lindner , Adrian Daerr , Andrew Murray
Biophysical Journal, 2014, 106 (10), pp.2214-2221. ⟨10.1016/j.bpj.2014.02.040⟩
Article dans une revue hal-03761718v1
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An agent-based model of dune interactions produces the emergence of patterns in deserts

Mathieu Génois , Sylvain Courrech Du Pont , Pascal Hersen , Guillaume Grégoire
Geophysical Research Letters, 2013, 40, pp.3909. ⟨10.1002/grl.50757⟩
Article dans une revue hal-00759289v2

Severe osmotic compression triggers a slowdown of intracellular signaling, which can be explained by molecular crowding.

Agnès Miermont , François Waharte , Shiqiong Hu , Megan Nicole Mcclean , Samuel Bottani
Proceedings of the National Academy of Sciences of the United States of America, 2013, 110 (14), pp.5725-30. ⟨10.1073/pnas.1215367110⟩
Article dans une revue hal-00817393v1
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Spatial structuring and size selection as collective behaviours in an agent-based model for barchan fields.

Mathieu Génois , Pascal Hersen , Sylvain Courrech Du Pont , Guillaume Grégoire
The European Physical Journal B: Condensed Matter and Complex Systems, 2013, 86 (11), pp.447. ⟨10.1140/epjb/e2013-40710-2⟩
Article dans une revue hal-00869412v1
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Long-term model predictive control of gene expression at the population and single-cell levels

Jannis Uhlendorf , Agnès Miermont , Thierry Delaveau , Gilles Charvin , Francois Fages
Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (35), pp.14271-14276. ⟨10.1073/pnas.1206810109⟩
Article dans une revue hal-01528440v1

Emerging modes of collective cell migration induced by geometrical constraints

Sri Ram Krishna Vedula , Man Chun Leong , Tan Lei Lai , Pascal Hersen , Alexandre Kabla
Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (32), pp.12974-12979. ⟨10.1073/pnas.1119313109⟩
Article dans une revue hal-03761712v1

Evidence of a large-scale mechanosensing mechanism for cellular adaptation to substrate stiffness

Léa Trichet , Jimmy Le Digabel , Rhoda Hawkins , Sri Ram Krishna Vedula , Mukund Gupta
Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (18), pp.6933-6938. ⟨10.1073/pnas.1117810109⟩
Article dans une revue hal-03761708v1

Cell crawling mediates collective cell migration to close undamaged epithelial gaps

Ester Anon , Xavier Serra-Picamal , Pascal Hersen , Nils Gauthier , Michael Sheetz
Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (27), pp.10891-10896. ⟨10.1073/pnas.1117814109⟩
Article dans une revue hal-03761707v1

Locomotion Control of Caenorhabditis elegans through Confinement

Félix Lebois , Pascal Sauvage , Charlotte Py , Olivier Cardoso , Benoît Ladoux
Biophysical Journal, 2012, 102 (12), pp.2791-2798. ⟨10.1016/j.bpj.2012.04.051⟩
Article dans une revue hal-03761705v1

Micro-patterned porous substrates for cell-based assays

Fanny Evenou , Jean-Marc Di Meglio , Benoit Ladoux , Pascal Hersen
Lab on a Chip, 2012, 12 (9), pp.1717. ⟨10.1039/C2LC20696J⟩
Article dans une revue hal-03761704v1

Mechanics of cell spreading within 3D-micropatterned environments

Marion Ghibaudo , Jean-Marc Di Meglio , Pascal Hersen , Benoit Ladoux
Lab on a Chip, 2011, 11 (5), pp.805-812. ⟨10.1039/C0LC00221F⟩
Article dans une revue hal-03761693v1

Polygon formation and surface flow on a rotating fluid surface

R. Bergmann , L. Tophøj , T. Homan , P. Hersen , A. Andersen
Journal of Fluid Mechanics, 2011, 679, pp.415-431. ⟨10.1017/jfm.2011.152⟩
Article dans une revue hal-03761702v1

Push it, pull it

Pascal Hersen , Benoît Ladoux
Nature, 2011, pp.340-341. ⟨10.1038/470340a⟩
Article dans une revue hal-03761744v1

The Dynamical Systems Properties of the HOG Signaling Cascade

Agnès Miermont , Jannis Uhlendorf , Megan Mcclean , Pascal Hersen
Journal of Signal Transduction, 2011, 2011, pp.1-12. ⟨10.1155/2011/930940⟩
Article dans une revue hal-03761696v1

Running Worms: C. elegans Self-Sorting by Electrotaxis

Xavier Manière , Félix Lebois , Ivan Matic , Benoit Ladoux , Jean-Marc Di Meglio
PLoS ONE, 2011, 6 (2), pp.e16637. ⟨10.1371/journal.pone.0016637⟩
Article dans une revue hal-03761699v1

Towards Real-Time Control of Gene Expression: in silico Analysis*

Jannis Uhlendorf , Pascal Hersen , Gregory Batt
IFAC Proceedings Volumes, 2011, 44 (1), pp.14844-14850. ⟨10.3182/20110828-6-IT-1002.02614⟩
Article dans une revue hal-03761737v1

Magnetic micropillars as a tool to govern substrate deformations

Jimmy Le Digabel , Nicolas Biais , Jérôme Fresnais , Jean-François Berret , Pascal Hersen
Lab on a Chip, 2011, 11 (15), ⟨10.1039/C1LC20263D⟩
Article dans une revue hal-01378197v1

Formation and stability of transverse and longitudinal sand dunes

Erwan Reffet , Sylvain Courrech Du Pont , Pascal Hersen , Stéphane Douady
Geology, 2010, 38 (6), pp.491-494. ⟨10.1130/G30894.1⟩
Article dans une revue hal-03761691v1

Traction forces exerted by epithelial cell sheets

Alexandre Saez , Ester Anon , Marion Ghibaudo , Olivia Du Roure , Jean-Marc Di Meglio
Journal of Physics: Condensed Matter, 2010, 22 (19), pp.194119. ⟨10.1088/0953-8984/22/19/194119⟩
Article dans une revue hal-03761689v1

Strength Dependence of Cadherin-Mediated Adhesions

Benoit Ladoux , Ester Anon , Mireille Lambert , Aleksandr Rabodzey , Pascal Hersen
Biophysical Journal, 2010, 98 (4), pp.534-542. ⟨10.1016/j.bpj.2009.10.044⟩
Article dans une revue hal-03761686v1
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Substrate topography induces a cross-over from 2D to 3D behavior in fibroblast migration

Marion Ghibaudo , Léa Trichet , Jimmy Le Digabel , Alain Richert , Pascal Hersen
Biophysical Journal, 2009, 97 (1), pp.357-368. ⟨10.1016/j.bpj.2009.04.024⟩
Article dans une revue hal-00410702v1

Signal processing by the HOG MAP kinase pathway

Pascal Hersen , Megan Nicole Mcclean , Lakshminarayanan Mahadevan , Sharad Ramanathan
Proceedings of the National Academy of Sciences of the United States of America, 2008, 105 (20), pp.7165-7170. ⟨10.1073/pnas.0710770105⟩
Article dans une revue hal-00321259v1

Dynamic analysis of cell signalling

Pascal Hersen , Megan Mcclean , Sharad Ramanathan
Médecine/Sciences, 2008, 24 (12), pp.1020-1022. ⟨10.1051/medsci/200824121020⟩
Article dans une revue hal-03761748v1
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Genetic drift at expanding frontiers promotes gene segregation

Oskar Hallatschek , Pascal Hersen , Sharad Ramanathan , David R. Nelson
Proceedings of the National Academy of Sciences of the United States of America, 2007, 104, pp.19926-19930. ⟨10.1073/pnas.0710150104⟩
Article dans une revue hal-00321262v1

Song of the Dunes as a Self-Synchronized Instrument

S. Douady , A. Manning , P. Hersen , H. Elbelrhiti , S. Protière
Physical Review Letters, 2006, 97 (1), pp.018002. ⟨10.1103/PhysRevLett.97.018002⟩
Article dans une revue hal-03761661v1
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The song of the dunes as a self-synchronized instrument

Stéphane Douady , Audrey Manning , Pascal Hersen , Hicham Elbelrhiti , Suzie Protière
Physical Review Letters, 2006, 97 (1), pp.018002. ⟨10.1103/PhysRevLett.97.018002⟩
Article dans une revue hal-00135892v1

Polygons on a Rotating Fluid Surface

Thomas Jansson , Martin Haspang , Kåre Jensen , Pascal Hersen , Tomas Bohr
Physical Review Letters, 2006, 96 (17), pp.174502. ⟨10.1103/PhysRevLett.96.174502⟩
Article dans une revue hal-03761666v1
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Polygons on a Rotating Fluid Surface

Thomas Jansson , Martin Haspang , Kåre H. Jensen , Pascal Hersen , Tomas Bohr
Physical Review Letters, 2006, 96 (17), pp.174502. ⟨10.1103/PhysRevLett.96.174502⟩
Article dans une revue hal-00135893v1

Collision of barchan dunes as a mechanism of size regulation

Pascal Hersen , Stéphane Douady
Geophysical Research Letters, 2005, 32 (21), pp.L21403. ⟨10.1029/2005GL024179⟩
Article dans une revue hal-03761654v1

Flow effects on the morphology and dynamics of aeolian and subaqueous barchan dunes

Pascal Hersen
Journal of Geophysical Research: Earth Surface, 2005, 110 (F4), pp.n/a-n/a. ⟨10.1029/2004JF000185⟩
Article dans une revue hal-03761625v1

On the crescentic shape of barchan dunes

P. Hersen
The European Physical Journal B: Condensed Matter and Complex Systems, 2004, 37 (4), pp.507-514. ⟨10.1140/epjb/e2004-00087-y⟩
Article dans une revue hal-03761616v1

Corridors of barchan dunes: stability and size selection

Pascal Hersen , Ken H. Andersen , Hicham Elbelrhiti , Bruno Andreotti , Philippe Claudin
Physical Review E : Statistical, Nonlinear, and Soft Matter Physics, 2004, 69 (1), pp.011304. ⟨10.1103/PhysRevE.69.011304⟩
Article dans une revue hal-00009356v1

Relevant Length Scale of Barchan Dunes

Pascal Hersen , Stéphane Douady , Bruno Andreotti
Physical Review Letters, 2002, 89 (26), pp.264301. ⟨10.1103/PhysRevLett.89.264301⟩
Article dans une revue hal-03761584v1

Microfluidic Platforms for Generating Dynamic Environmental Perturbations to Study the Responses of Single Yeast Cells

Anjali Bisaria , Pascal Hersen , Megan Mcclean
Yeast Genetics, 1205, Springer New York, pp.111-129, 2014, Methods in Molecular Biology, ⟨10.1007/978-1-4939-1363-3_8⟩
Chapitre d'ouvrage hal-03761742v1

In silico control of biomolecular processes

Jannis Uhlendorf , Agnès Miermont , Thierry Delaveau , Gilles Charvin , François Fages
Mario A. Marchisio. Computational Methods in Synthetic Biology, 1244, Springer New York, pp.8, 2014, Methods in Molecular Biology, 978-1-4939-1877-5. ⟨10.1007/978-1-4939-1878-2_13⟩
Chapitre d'ouvrage hal-01104057v1

Micropatterned Porous Membranes for Combinatorial Cell-Based Assays

Clément Vulin , Fanny Evenou , Jean-Marc Di Meglio , Pascal Hersen
Micropatterning in Cell Biology Part C, 121, Elsevier, pp.155-169, 2014, Methods in Cell Biology, ⟨10.1016/b978-0-12-800281-0.00011-7⟩
Chapitre d'ouvrage hal-03761739v1

Towards Real-Time Control of Gene Expression at the Single Cell Level: A Stochastic Control Approach

Lakshmeesh Maruthi , Ilya Tkachev , Alfonso Carta , Eugenio Cinquemani , Pascal Hersen
Computational Methods in Systems Biology, 8859, Springer International Publishing, pp.155-172, 2014, Lecture Notes in Computer Science, 978-3-319-12981-5. ⟨10.1007/978-3-319-12982-2_12⟩
Chapitre d'ouvrage hal-01096959v1

Measuring In Vivo Signaling Kinetics in a Mitogen-Activated Kinase Pathway Using Dynamic Input Stimulation

Megan Mcclean , Pascal Hersen , Sharad Ramanathan
Yeast Genetic Networks, 734, Humana Press, pp.101-119, 2011, Methods in Molecular Biology, ⟨10.1007/978-1-61779-086-7_6⟩
Chapitre d'ouvrage hal-03761745v1

Dunes, the Collective Behaviour of Wind and Sand, or: Are Dunes Living Beings?

Stéphane Douady , Pascal Hersen
Morphogenesis, Springer Berlin Heidelberg, pp.107-118, 2011, ⟨10.1007/978-3-642-13174-5_6⟩
Chapitre d'ouvrage hal-03761749v1

Towards real-time control of gene expression : controlling the hog signaling cascade

Jannis Uhlendorf , Samuel Bottani , François Fages , Pascal Hersen , Grégory Batt
Russ B. Altman; A. Keith Dunker; Lawrence Hunter; Tiffany A. Murray; Teri E. Klein. Biocomputing 2011, World Scientific, pp.338-349, 2010, ⟨10.1142/9789814335058_0035⟩
Chapitre d'ouvrage hal-03761738v1
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Morphogenese et Dynamique des Barchanes

Pascal Hersen
Dynamique des Fluides [physics.flu-dyn]. Université Paris-Diderot - Paris VII, 2004. Français. ⟨NNT : ⟩
Thèse tel-00008602v1