Hélène RATINEY, is a permanently employed research scientist at CNRS . Her expertise is in in vivo NMR spectroscopy (quantification methods, MRI/MRS - MRSI specific analysis, sampling strategies ).
Following an engineering degree in Electrical Engineering from ENSEEIHT, Toulouse, France, and a M.Sc. degree in Signal Processing from the National Polytechnic Institute of Toulouse (both obtained in 2001), Hélène Ratiney received the PhD degree in ‘signal and Image’ from the Lyon 1 University in October 2004. Her phD project was devoted to the development of quantification methods for 1D MRS short echo time in vivo spectroscopy (method QUEST). During a post-doctoral position (2005-2007, PI Daniel Pelletier and collaboration with Sarah Nelson), she was involved in a longitudinal study (EPIC/GeneMSA) conducted at UCSF San Francisco, that has followed 500 people with multiple sclerosis each year since 2004 with the purpose of capturing changes and learning factors that control the evolution of the disease. She developed quantification strategy for brain spectroscopic imaging data to reach tissue specific (white matter/ gray matter) biochemical information: metabolite T1, metabolite concentration.
She has currently four main lines of research: 1) signal processing for in vivo multi-dimensional MR spectroscopy, this includes exploration now method based on deep learning 2) in vivo MR spectroscopy of lipids, seeking correspondance/complementarity with quantitative MRI 3) sampling strategies to accelerate MRS/MRSI acquisition 4) optimal control for the design of RF pulses and use in vivo MRI/MRS
The clinical applications of her works are : neurodegenerative disease; cancer and skeletal muscle metabolism