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V1b vasopressin receptor trafficking and signaling: Role of arrestins, G proteins and Src kinase

Sanja Perkovska , Catherine Méjean , M. A. Ayoub , Juan Li , Floriane Hemery , et al.
Traffic, 2018, 19 (1), pp.58-82. ⟨10.1111/tra.12535⟩
Article dans une revue hal-02073197v1

Structures of the arginine-vasopressin and oxytocin receptor signaling complexes

Julien Bous , Aurélien Fouillen , Hélène Orcel , Sébastien Granier , Patrick Bron , et al.
Vitamins and hormones, 2023, Vitamins and Hormones, 123, pp.67-107. ⟨10.1016/bs.vh.2022.12.003⟩
Article dans une revue hal-04213123v1
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Structural insights into biased G protein-coupled receptor signaling revealed by fluorescence spectroscopy.

Rita Rahmeh , Marjorie Damian , Martin Cottet , Hélène Orcel , Christiane Mendre , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (17), pp.6733-8. ⟨10.1073/pnas.1201093109⟩
Article dans une revue inserm-00713711v1
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Structure of the antidiuretic hormone vasopressin receptor signalling complex.

Julien Bous , Hélène Orcel , Nicolas Floquet , Cedric Leyrat , Josephine Lai-Kee-Him , et al.
2020
Pré-publication, Document de travail hal-03088027v1
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Mechanisms involved in dual vasopressin/apelin neuron dysfunction during aging

J. Sauvant , Jean-Christophe Delpech , K. Palin , N. de Mota , J. Dudit , et al.
PLoS ONE, 2014, 9 (2), pp.e87421. ⟨10.1371/journal.pone.0087421⟩
Article dans une revue hal-01369526v1
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Heterodimerization with Its Splice Variant Blocks the Ghrelin Receptor 1a in a Non-signaling Conformation

Sophie Mary , Jean-Alain Fehrentz , Marjorie Damian , Gérald Gaibelet , Hélène Orcel , et al.
Journal of Biological Chemistry, 2013, 288 (34), pp.24656-24665. ⟨10.1074/jbc.M113.453423⟩
Article dans une revue hal-02871944v1

Green mamba peptide targets type-2 vasopressin receptor against polycystic kidney disease

Justyna Ciolek , Helen Reinfrank , Loïc Quinton , Say Viengchareun , Enrico A. Stura , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (27), pp.7154-7159. ⟨10.1073/pnas.1620454114⟩
Article dans une revue hal-02050051v1

Pharmacological characterization of volume-sensitive, taurine permeable anion channels in rat supraoptic glial cells

Vanessa Brès , Amandine Hurbin , Anne Duvoid , Hélène Orcel , Françoise C. Moos , et al.
British Journal of Pharmacology, 2000, 130, ⟨10.1038/sj.bjp.0703492⟩
Article dans une revue hal-02349501v1

Age-impaired fluid homeostasis depends on the balance of IL-6/IGF-I in the rat supraoptic nuclei

Karine Palin , Marie Moreau , Hélène Orcel , Anne Duvoid-Guillou , Alain Rabié , et al.
Neurobiology of Aging, 2009, 30 (10), pp.1677-1692. ⟨10.1016/j.neurobiolaging.2007.12.006⟩
Article dans une revue hal-02665167v1

The Vasopressin Receptors Colocalize with Vasopressin in the Magnocellular Neurons of the Rat Supraoptic Nucleus and Are Modulated by Water Balance

Amandine Hurbin , Hélène Orcel , Gérard Alonso , Françoise Moos , Alain Rabie
Endocrinology, 2002, 143 (2), pp.456-466. ⟨10.1210/endo.143.2.8643⟩
Article dans une revue hal-02349491v1
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Differential coupling of the vasopressin V1b receptor through compartmentalization within the plasma membrane.

Hélène Orcel , Laura Albizu , Sanja Perkovska , Thierry Durroux , Christiane Mendre , et al.
Molecular Pharmacology, 2009, 75 (3), pp.637-47. ⟨10.1124/mol.108.049031⟩
Article dans une revue inserm-00362611v1
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Cryo–electron microscopy structure of the antidiuretic hormone arginine-vasopressin V2 receptor signaling complex

Julien Bous , Hélène Orcel , Nicolas Floquet , Cedric Leyrat , Joséphine Lai-Kee-Him , et al.
Science Advances , 2021, 7 (21), pp.eabg5628. ⟨10.1126/sciadv.abg5628⟩
Article dans une revue hal-03240488v1

The V 1a and V 1b , But Not V 2 , Vasopressin Receptor Genes Are Expressed in the Supraoptic Nucleus of the Rat Hypothalamus, and the Transcripts Are Essentially Colocalized in the Vasopressinergic Magnocellular Neurons

Amandine Hurbin , Line Boissin-Agasse , Helene Orcel , Alain Rabié , Nathalie Joux , et al.
Endocrinology, 1998, 139, 11, pp.4701-4707. ⟨10.1210/endo.139.11.6320⟩
Article dans une revue hal-02349512v1

Design, synthesis and biological studies of a library of NK1-Receptor Ligands Based on a 5-arylthiosubstituted 2-amino-4,6-diaryl-3-cyano-4 H -pyran core: Switch from antagonist to agonist effect by chemical modification

Rocío Recio , Empar Vengut-Climent , Bernard Mouillac , Hélène Orcel , Miguel López-Lázaro , et al.
European Journal of Medicinal Chemistry, 2017, 138, pp.644-660. ⟨10.1016/j.ejmech.2017.06.056⟩
Article dans une revue hal-02075064v1
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Interleukin-6 activates arginine vasopressin neurons in the supraoptic nucleus during immune challenge in rats

Karine Palin , Marie L. Moreau , Julie Sauvant , Hélène Orcel , Agnès Nadjar , et al.
AJP - Endocrinology and Metabolism, 2009, 296 (6), pp.E1289-E1299. ⟨10.1152/ajpendo.90489.2008⟩
Article dans une revue hal-02659072v1
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Structure of the vasopressin hormone–V2 receptor–β-arrestin1 ternary complex

Julien Bous , Aurélien Fouillen , Hélène Orcel , Stefano Trapani , Xiaojing Cong , et al.
Science Advances , 2022, 8 (35), pp.eabo7761. ⟨10.1126/sciadv.abo7761⟩
Article dans une revue hal-03790728v1
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Leukotriene BLT2 receptor monomers activate the G(i2) GTP-binding protein more efficiently than dimers.

Laure Arcemisbehere , Tuhinadri Sen , Laure Boudier , Marie-Noëlle Balestre , Gérald Gaibelet , et al.
Journal of Biological Chemistry, 2010, 285 (9), pp.6337-47. ⟨10.1074/jbc.M109.083477⟩
Article dans une revue inserm-00457594v1

Structural difference between heteromeric somatic and homomeric axonal glycine receptors in the hypothalamo-neurohypophysial system

C. Deleuze , M. Runquist , Hélène Orcel , Alain Rabié , G. Dayanithi , et al.
Neuroscience, 2005, 135, pp.475-483. ⟨10.1016/j.neuroscience.2005.05.024⟩
Article dans une revue istex hal-00016952v1