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Structural mechanism of signal transduction between the RNA-binding domain and the PTS-regulation domain of the LicT antiterminator.

Hélène Déméné , Thierry Ducat , Karine de Guillen , Catherine Birck , Stéphane Aymerich , et al.
Journal of Biological Chemistry, 2008, 283 (45), epub ahead of print. ⟨10.1074/jbc.M805955200⟩
Article dans une revue hal-00315576v1
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Resolving the activation mechanism of the D99N antiterminator LicT protein

Yinshan Yang , Jérôme Gracy , Nathalie Declerck , Héléne Démèné
Journal of Structural Biology, 2021, 213 (2), pp.107730. ⟨10.1016/j.jsb.2021.107730⟩
Article dans une revue hal-03088255v1

Low concentration of a Gd-chelate increases the signal-to-noise ratio in fast pulsing BEST experiments

Nathalie Sibille , Gaëtan Bellot , Jing Wang , Hélène Déméné
Journal of Magnetic Resonance, 2012, 224, pp.32-37. ⟨10.1016/j.jmr.2012.07.022⟩
Article dans une revue hal-02347955v1
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Cryo–electron microscopy structure of the antidiuretic hormone arginine-vasopressin V2 receptor signaling complex

Julien Bous , Hélène Orcel , Nicolas Floquet , Cedric Leyrat , Joséphine Lai-Kee-Him , et al.
Science Advances , 2021, 7 (21), pp.eabg5628. ⟨10.1126/sciadv.abg5628⟩
Article dans une revue hal-03240488v1

Propagation of conformational changes during μ-opioid receptor activation

Rémy Sounier , Camille Mas , Jan Steyaert , Toon Laeremans , Aashish Manglik , et al.
Nature, 2015, 524 (7565), pp.375-378. ⟨10.1038/nature14680⟩
Article dans une revue hal-02067220v1
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Structure Structural insights into the allosteric activation of the LicT antiterminator by PTS- mediated phosphorylation

Yinshan Yang , André Padilla , Karine de Guillen , Léa Mammri , Jérôme Gracy , et al.
Structure, 2020, 28 (2), pp.244-251.e3. ⟨10.1016/j.str.2019.10.017⟩
Article dans une revue hal-02368196v1
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An original structural fold underlies the multitask P1, a silencing suppressor encoded by the Rice yellow mottle virus

Vianney Poignavent , François Hoh , Guillaume Terral , Yang Yinshan , François-Xavier Gillet , et al.
2020
Pré-publication, Document de travail hal-03076418v1
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Molecular insights into the biased signaling mechanism of the μ-opioid receptor

Xiaojing Cong , Damien Maurel , Héléne Démèné , Ieva Vasiliauskaité-Brooks , Joanna Hagelberger , et al.
Molecular Cell, In press, 81 (20), pp.4165-4175.e6. ⟨10.1016/j.molcel.2021.07.033⟩
Article dans une revue hal-03331072v1
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Structure of the antidiuretic hormone vasopressin receptor signalling complex.

Julien Bous , Hélène Orcel , Nicolas Floquet , Cedric Leyrat , Josephine Lai-Kee-Him , et al.
2020
Pré-publication, Document de travail hal-03088027v1
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A Flexible and Original Architecture of Two Unrelated Zinc Fingers Underlies the Role of the Multitask P1 in RYMV Spread

Vianney Poignavent , François Hoh , Guillaume Terral , Yinshan Yang , François-Xavier Gillet , et al.
Journal of Molecular Biology, 2022, 434 (16), pp.167715. ⟨10.1016/j.jmb.2022.167715⟩
Article dans une revue hal-03758984v1
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The Human Mixed Lineage Leukemia 5 (MLL5), a Sequentially and Structurally Divergent SET Domain-Containing Protein with No Intrinsic Catalytic Activity

Sarah Mas-Y-Mas , Marta Barbon , Catherine Teyssier , Hélène Déméné , João E Carvalho , et al.
PLoS ONE, 2016, 11 (11), pp.e0165139. ⟨10.1371/journal.pone.0165139⟩
Article dans une revue hal-01394662v1

Pathological Interactions Between Mutant Thyroid Hormone Receptors and Corepressors and Their Modulation by a Thyroid Hormone Analogue with Therapeutic Potential

Déborah Harrus , Héléne Démèné , Edwin Vasquez , Abdelhay Boulahtouf , Pierre Germain , et al.
Thyroid, 2018, 28 (12), pp.1708-1722. ⟨10.1089/thy.2017.0551⟩
Article dans une revue hal-02322894v1

PEGylation rate influences peptide-based nanoparticles mediated siRNA delivery in vitro and in vivo

Gudrun Aldrian , Anaïs Vaissière , Karidia Konate , Quentin Seisel , Eric Vivès , et al.
Journal of Controlled Release, 2017, 256, pp.79-91. ⟨10.1016/j.jconrel.2017.04.012⟩
Article dans une revue hal-02197250v1
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NMR chemical shift assignment of a constitutively active fragment of the antitermination protein LicT

Yinshan Yang , Nathalie Declerck , Héléne Démèné
Biomolecular NMR Assignments, 2020, 14, pp.19-22. ⟨10.1007/s12104-019-09914-w⟩
Article dans une revue hal-02322846v1
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Biased activation of the vasopressin V2 receptor probed by NMR, paramagnetic ligands, and molecular dynamics simulations

Gérald Gaibelet , Aurélien Fouillen , Stéphanie Riché , Hélène Orcel , Christiane Mendre , et al.
2022
Pré-publication, Document de travail hal-03756232v1
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NMR chemical shift backbone assignment of the viral protein P1 encoded by the African Rice Yellow Mottle Virus

Yinshan Yang , Vianney Poignavent , François-Xavier Gillet , Florence Vignols , Héléne Démèné
Biomolecular NMR Assignments, 2019, 13 (2), pp.345-348. ⟨10.1007/s12104-019-09903-z⟩
Article dans une revue hal-02322880v1

Rapid determination of protein solubility and stability conditions for NMR studies using incomplete factorial design

Thierry Ducat , Nathalie N. Declerck , Thierry Gostan , Michel Kochoyan , Hélène Déméné
Journal of Biomolecular NMR, 2006, 34 (3), pp.137-151. ⟨10.1007/s10858-006-0003-0⟩
Article dans une revue istex hal-02668430v1

The multifunctional protein GC1q-R interacts specifically with the i3 loop arginine cluster of the vasopressin V-2 receptor

Sebastien Granier , Frederic Jean-Alphonse , Daniel Bacqueville , Arnaud Monteil , Robert Pascal , et al.
Regulatory Peptides, 2008, 148, pp.76-87. ⟨10.1016/j.regpep.2008.01.007⟩
Article dans une revue istex hal-00493436v1

1H, 13C and 15N backbone chemical shift assignments of camelid single-domain antibodies against active state µ-opioid receptor

Rémy Sounier , Yinshan Yang , Joanna Hagelberger , Sébastien Granier , Héléne Démèné
Biomolecular NMR Assignments, 2017, 11 (1), pp.117-121. ⟨10.1007/s12104-017-9733-z⟩
Article dans une revue hal-02075373v1

Design and synthesis of cyclic and linear peptide-agarose tools for baiting interacting protein partners of GPCRs

Sébastien Granier , Frédéric Jean-Alphonse , Hélène Déméné , Gilles Guillon , Robert Pascal , et al.
Bioorganic and Medicinal Chemistry Letters, 2006, 16 (3), pp.521-524. ⟨10.1016/j.bmcl.2005.10.061⟩
Article dans une revue istex hal-03117141v1

Expression, purification and NMR characterization of the cyclic recombinant form of the third intracellular loop of the vasopressin type 2 receptor

Gaëtan Bellot , Robert Pascal , Christiane Mendre , Serge Urbach , Bernard Mouillac , et al.
Protein Expression and Purification, 2011, 78, pp.131-138. ⟨10.1016/j.pep.2011.04.020⟩
Article dans une revue istex hal-00772819v1

Structure of the third Intracellular Loop of the Vasopressin V2 receptor and Conformational Changes upon Binding to gC1qR

Gaëtan Bellot , Sébastien Granier , William Bourguet , René Seyer , Rita Rahmeh , et al.
Journal of Molecular Biology, 2009, 388 (3), pp.491-507. ⟨10.1016/j.jmb.2009.02.065⟩
Article dans une revue istex hal-00554741v1