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Synthesis of functionalized alkoxyalkylidene gem-bisphosphonates

 Jean-Pierre Haelters , Hélène Couthon , Alan Le Goff , Gaelle Simon , Bernard Corbel , et al.
Tetrahedron, 2008, 64 (27), pp.6537 - 6543. ⟨10.1016/j.tet.2008.04.052⟩
Article dans une revue istex hal-01580463v1

DiGalactosyl-Glycero-Ether Lipid: synthetic approaches and evaluation as SK3 channel inhibitor.

 Charlotte Sevrain , Jean-Pierre Haelters , Aurélie Chantôme , Hélène Couthon , Maxime Gueguinou , et al.
Organic & Biomolecular Chemistry, 2013, 11 (27), pp.4479-87. ⟨10.1039/c3ob40634b⟩
Article dans une revue inserm-00848879v1
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Atherton–Todd reaction: mechanism, scope and applications

 Stéphanie S Le Corre , Mathieu Berchel , Hélène Couthon , Jean-Pierre Haelters , Paul-Alain Jaffres
Beilstein Journal of Organic Chemistry, 2014, 10, pp.1166 - 1196. ⟨10.3762/bjoc.10.117⟩
Article dans une revue hal-01517766v1

Trimethylarsonium-Based Cationic Phospholipids for Gene Delivery

 Mathieu Berchel , Stéphanie Le Corre , Tony Le Gall , Hélène Couthon , Jean-Pierre Haelters , et al.
Phosphorus, Sulfur, and Silicon and the Related Elements, 2013, 188 (1-3), pp.91-94. ⟨10.1080/10426507.2012.741161⟩
Article dans une revue hal-02070718v1

New Disaccharide-Based Ether Lipids as SK3 Ion Channel Inhibitors

 Wilfried Berthe , Charlotte Sevrain , Aurélie Chantôme , Ana Maria Bouchet , Maxime Gueguinou , et al.
ChemMedChem, 2016, 11 (14), pp.1531 - 1539. ⟨10.1002/cmdc.201600147⟩
Article dans une revue istex hal-01474320v1
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Synthesis of Alkyl-Glycerolipids Standards for Gas Chromatography Analysis: Application for Chimera and Shark Liver Oils

 Michelle Pinault , Cyrille Guimaraes , Hélène Couthon , Jérôme Thibonnet , Delphine Fontaine , et al.
Marine drugs, 2018, 16 (4), ⟨10.3390/md16040101⟩
Article dans une revue hal-01744078v1

Novel branched amphiphilic lipids

 Paul-Alain Jaffres , Hélène Couthon , Damien Afonso , Tristan Montier , Tony Le Gall
France, Patent n° : WO2017051129 A1. 2015
Brevet hal-01532123v1

New alkyl-lipid blockers of SK3 channels reduce cancer-cell migration and occurrence of metastasis

 Alban Girault , Jean-Pierre Haelters , Marie Potier-Cartereau , Aurélie Chantôme , Michelle Pinault , et al.
Current Cancer Drug Targets, 2011, 11, pp.1111-1125
Article dans une revue inserm-00662356v1

New Lipo-Phosphoramidates for Gene Delivery

 Paul-Alain Jaffres , Aurore Fraix , Christophe Lorilleux , Mathieu Berchel , Hélène Couthon , et al.
Phosphorus, Sulfur, and Silicon and the Related Elements, 2011, 186 (4), pp.918-920. ⟨10.1080/10426507.2010.522639⟩
Article dans une revue hal-00614938v1

Designing of a Magnetodielectric System in Hybrid Organic-inorganic framework, a Perovskite Layered Phosphonate MnO3PC6H4-m-Br.H2O

 Tathamay Basu , Clarisse Bloyet , Felicien Beaubras , Vincent Caignaert , Olivier Pérez , et al.
Advanced Functional Materials, 2019, 29 (33), pp.1901878. ⟨10.1002/adfm.201901878⟩
Article dans une revue hal-02159971v1

New Alkyl-Lipid Blockers of SK3 Channels Reduce Cancer Cell Migration and Occurrence of Metastasis

 Alain Girault , Jean-Pierre Haelters , Marie Potier-Cartereau , Aurélie Chantome , Michelle Pinault , et al.
Current Cancer Drug Targets, 2011, 11 (9), pp.1111 - 1125. ⟨10.2174/156800911798073069⟩
Article dans une revue hal-01577240v1

Influence of the Lipid Domain on the Supramolecular Assemblies of Cationic Lipids. Characterization by Solid-State 31P and 2H NMR Spectroscopy

 Damien Afonso , Hélène Couthon , Mathieu Berchel , Axelle Grelard , Erick J. Dufourc , et al.
Phosphorus, Sulfur, and Silicon and the Related Elements, 2015, 190 (5-6), pp.896-898. ⟨10.1080/10426507.2014.974750⟩
Article dans une revue hal-02123944v1

Cationic lipo-thiophosphoramidates for gene delivery: synthesis, physico-chemical characterization and gene transfection activity – comparison with lipo-phosphoramidates

 Aurore Fraix , Tristan Montier , Nathalie Carmoy , Damien Loizeau , Laure Burel-Deschamps , et al.
Organic & Biomolecular Chemistry, 2011, 9 (7), ⟨10.1039/C0OB00981D⟩
Article dans une revue hal-01577011v1

Rigid phosphonic acid for the construction of crystalline organic-inorganic hybrid materials

 Mélissa Roger , Clarisse Bloyet , Quentin Evrard , Hélène Couthon , Mathieu Berchel , et al.
Phosphorus, Sulfur, and Silicon and the Related Elements, 2016, 191 (11-12), pp.1482 - 1484. ⟨10.1080/10426507.2016.1212048⟩
Article dans une revue hal-01539339v1
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Development of pyrene-based fluorescent ether lipid as inhibitor of SK3 ion channels

 Alicia Bauduin , Marion Papin , Aurélie Chantôme , Hélène Couthon , Laure Burel-Deschamps , et al.
European Journal of Medicinal Chemistry, 2021, 209, pp.112894. ⟨10.1016/j.ejmech.2020.112894⟩
Article dans une revue hal-02997273v1

Glyco-Phospho-Glycero Ether Lipids (GPGEL): synthesis and evaluation as small conductance Ca2+-activated K+ channel (SK3) inhibitors

 Charlotte M. Sevrain , Jean-Pierre Haelters , Aurélie Chantôme , Hélène Couthon , Alban Girault , et al.
MedChemComm, 2012, 3 (11), ⟨10.1039/C2MD20207G⟩
Article dans une revue hal-01556890v1

The gene transfection properties of a lipophosphoramidate derivative with two phytanyl chains

 Mattias F. Lindberg , Nathalie Carmoy , Tony Le Gall , Aurore Fraix , Mathieu Berchel , et al.
Biomaterials, 2012, 33 (26), pp.6240 - 6253. ⟨10.1016/j.biomaterials.2012.05.014⟩
Article dans une revue istex hal-01559108v1

Lipophosphonate/lipophosphoramidates: a family of synthetic vectors efficient for gene delivery.

 Mathieu Berchel , Tony Le Gall , Hélène Couthon , Jean-Pierre Haelters , Tristan Montier , et al.
Biochimie, 2012, 94 (1), pp.33-41. ⟨10.1016/j.biochi.2011.07.026⟩
Article dans une revue istex hal-00721772v1

Modular Construction of Fluorescent Lipophosphoramidates by Click Chemistry

 Mathieu Berchel , Jean-Piere Haelters , Hélène Couthon , Laure Burel-Deschamps , Patrick Midoux , et al.
European Journal of Organic Chemistry, 2011, 31, pp.6294-6303. ⟨10.1002/ejoc.201100900⟩
Article dans une revue istex hal-00720537v1
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M(H2O)(PO3C10H6OH)·(H2O)0.5 (M = Co, Mn, Zn, Cu): a new series of layered metallophosphonate compoundsobtained from 6-hydroxy-2-naphthylphosphonic acid

 Felicien Beaubras , Jean-Michel Rueff , Olivier Perez , Fabien Veillon , Vincent Caignaert , et al.
Dalton Transactions, 2020, 49 (12), pp.3877-3891. ⟨10.1039/C9DT03947C⟩
Article dans une revue hal-02413390v1

Phosphonic acid: preparation and applications

 Charlotte M. Sevrain , Mathieu Berchel , Hélène Couthon , Paul-Alain Jaffres
Beilstein Journal of Organic Chemistry, 2017, 13, pp.2186 - 2213. ⟨10.3762/bjoc.13.219⟩
Article dans une revue hal-01624628v1

An unexpected base-induced [1,4]-phospho-Fries rearrangement

 Mathieu Berchel , Jean-Yves Salaün , Hélène Couthon , Jean-Pierre Haelters , Paul-Alain Jaffres
Dalton Transactions, 2010, 39 (47), ⟨10.1039/C0DT00880J⟩
Article dans une revue istex hal-01577411v1

Triggering bilayer to inverted-hexagonal nanostructure formation by thiol–ene click chemistry on cationic lipids: consequences on gene transfection

 Damien Afonso , Tony Le Gall , Hélène Couthon , Axelle Grélard , Shipra Prakash , et al.
Soft Matter, 2016, 12 (20), pp.4516 - 4520. ⟨10.1039/c6sm00609d⟩
Article dans une revue hal-01517791v1

Alkyl ether lipids, ion channels and lipid raft reorganization in cancer therapy

 Paul-Alain Jaffres , Gajate Consuelo , Ana Bouchet , Hélène Couthon , Aurélie Chantôme , et al.
Pharmacology and Therapeutics, 2016, ⟨10.1016/j.pharmthera.2016.06.003⟩
Article dans une revue inserm-01330970v1

Synthetic phospholipids and phospho-bola-amphiphiles for nucleic acid delivery

 Mathieu Berchel , Olivier Lozach , Wilfried Berthe , Sylvie Hernot , Hélène Couthon , et al.
Phosphorus, Sulfur, and Silicon and the Related Elements, 2016, 191 (11-12), pp.1485 - 1487. ⟨10.1080/10426507.2016.1212049⟩
Article dans une revue hal-01539538v1

Thio-ether functionalized glycolipid amphiphilic compounds reveal a potent activator of SK3 channel with vasorelaxation effect

 Charlotte Sevrain , Delphine Fontaine , Alicia Bauduin , Maxime Guéguinou , Bei Li Zhang , et al.
Organic & Biomolecular Chemistry, 2021, 19 (12), pp.2753-2766. ⟨10.1039/D1OB00021G⟩
Article dans une revue hal-03187829v1

Biophysical properties of cationic lipophosphoramidates: Vesicle morphology, bilayer hydration and dynamics

 Damien Loizeau , Piotr Jurkiewicz , Gokcan Aydogan , Anatoly A. Philimonenko , Selim Mahfoudhi , et al.
Colloids and Surfaces B: Biointerfaces, 2015, 136, pp.192 - 200. ⟨10.1016/j.colsurfb.2015.09.012⟩
Article dans une revue hal-01538480v1

Glyco-phospho-glycero-ether lipid as modulator of SK3 ion channel and SK3-dependent cancer cell migration

 C. Sevrain , Wilfried Berthe , Hélène Couthon , J. P. Haelters , M. Bouchet , et al.
Phosphorus, Sulfur, and Silicon and the Related Elements, 2016, 191 (11-12), pp.1623 - 1624. ⟨10.1080/10426507.2016.1217221⟩
Article dans une revue hal-01539329v1

MODULAR CONSTRUCTION OF LIPOPHOSPHOLIPIDS

 Jean-Pierre Haelters , Mathieu Berchel , Hélène Couthon , Paul-Alain Jaffres
France, Patent n° : WO 2012004419 A2. 2012
Brevet hal-01620524v1

Lead(II) Hybrid Materials from 3- or 4-Phosphonobenzoic Acid

 Jean-Michel Rueff , Olivier Perez , André Leclaire , Hélène Couthon , Paul-Alain Jaffres
European Journal of Inorganic Chemistry, 2009, 2009 (32), pp.4870 - 4876. ⟨10.1002/ejic.200900430⟩
Article dans une revue istex hal-01580241v1
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