Harold Duruflé
12
Documents
Affiliations actuelles
- 1007171
Identifiants chercheurs
- harold-durufle
- 0000-0002-6020-2822
- IdRef : 233622861
Présentation
RESEARCH EXPERIENCE
===================
2021
**Research Scientist: Integrative genomic prediction of complex phenotypes using system biology approach**
**-** Integrated Biology for the Development of Tree and Forest Diversity Laboratory, UMR INRAE/ONF 0588
2017
**PostDoc position: Develop the systems biology approach within the [SUNRISE project](https://www6.inrae.fr/sunrise/What-is-SUNRISE) ; 3 years**
\- Laboratory of Plant-Microbe Interactions, UMR 2594/441 CNRS/INRA, Toulouse, France
\- Team: Sunflower Genetics and Genomics (N. Langlade)
2014
**PhD: “Production and treatment of heterogeneous Omics data in order to study the cell wall plasticity in *A. thaliana* ecotypes living at contrasted altitudinal level”; 3 years**
\- Plant Science Research Laboratory, UMR 5546 UPS/CNRS, Toulouse, France (Pr C. Dunand)
\- Toulouse Mathematics Institute, France (Pr P. Besse)
2014
**Crop ontology curator. Bioversity International, Montpellier Office (France); 10 months**
Team: Crop Ontology project of the Generation Challenge Programme (E. Arnaud)
Internship:
2013
**Station Biologique de Roscoff, Marine Plants and Biomolecules, UMR 7139 UPMC/CNRS; 6 months**
2012
**Laboratory “Ecosystems, Biodiversity, Evolution”, UMR 6553 Rennes 1 University/CNRS; 3 months**
2011
**Laboratory of Plants Ecophysiological Responses to Environmental Stress, INRA Montpellier; 6 months**
2010
**Laboratory “Ecology Systematic Evolution”, Paris-Sud 11 University; 4 months**
Team: Photosynthesis, environment and adaptation (P. Streb & G. Cornic)
2004-2011
**Joseph Fourier Alpine Station, Alpine Botanical garden of Lautaret; Internship 2 months / year**
EDUCATION
==========
2013
**M.Sc. Degree: Integrative plant biology: Gene, Plant, Agro-system**
6 collaborating universities & Agrocampus Ouest (France)
*Major: Physiology/Metabolism and Eco-Physiology.*
2011
**BSc Degree: Functional Plant Biology**
Montpellier 2 University (France)
TEACHING and MENTORING
======================
**Supervision:**
PhD:
**2021-2022** - Abdou Rahmane Wade. Improved genome-based phenotypic predictions with a systems biology approach. (Co-doctoral advisor: Leopoldo Sanchez Rodriguez & Vincent Segura)
**2022-on going** - Alexandre Duplan. Improvement of pan-genomic knowledge and prediction of complex phenotypes by an integrative multi-omics approach. (Co-doctoral advisor: Leopoldo Sanchez Rodriguez & Stephane Maury)
PostDoc:
**2022** - Xabi Cazenave : Postdoc: 11 months
Internship:
**2023** - Alae-Eddine LEKCHIRI, Master degree, Rennes University
**2023** - Maya Doureradjam. Master degree, Montpellier University (France): 6 months
**2022** - Julien Desforges. Master degree, Orleans University (France): 4 months
**2018** - Claire Espérou. 4th year in mathematics and modelling engineering school of INSA, Toulouse (France): 3 months
**2017** - Sébastien Viudes. Master degree, Toulouse University (France): 2 months
**2016** - Merwann Selmani. 4th year in mathematics and modelling engineering school of INSA, Toulouse (France): 3 months
**2015** - Duchesse Lacour Mbadinga Mbadinga. BSc. Degree, Toulouse University (France): 6 months
Others:
**2019** - Caroline Laffray. Engineer: 1 year
**2018** - Charlotte Penouilh-Suzette. Engineer: 6 months
**Teaching:**
**2015 - 2017**: Toulouse University, biostatistics and biophysics at BSc. Degree, 70 h per year.
PROFESSIONAL SERVICES
=====================
International meeting organization committees of:
\- The [IX European Plant Science Retreat](http://epsr.net/), 20 - 23 June **2017**, Toulouse (France)
\- The [Workshop on Multivariate data integration using the R package mixOmics](http://mixomics.org/2016/05/12-14-sept-toulouse/), 12 - 14 September **2016**, Toulouse (France)
\- The [Workshop on Crop Ontology and Phenotyping Data Interoperability](https://sites.google.com/a/cgxchange.org/cropontologycommunity/), 31 March - 4 April **2014**, Montpellier (France)
RESEARCH EXPERIENCE
===================
2021
**Research Scientist: Integrative genomic prediction of complex phenotypes using system biology approach**
**-** Integrated Biology for the Development of Tree and Forest Diversity Laboratory, UMR INRAE/ONF 0588
2017
**PostDoc position: Develop the systems biology approach within the [SUNRISE project](https://www6.inrae.fr/sunrise/What-is-SUNRISE) ; 3 years**
\- Laboratory of Plant-Microbe Interactions, UMR 2594/441 CNRS/INRA, Toulouse, France
\- Team: Sunflower Genetics and Genomics (N. Langlade)
2014
**PhD: “Production and treatment of heterogeneous Omics data in order to study the cell wall plasticity in *A. thaliana* ecotypes living at contrasted altitudinal level”; 3 years**
\- Plant Science Research Laboratory, UMR 5546 UPS/CNRS, Toulouse, France (Pr C. Dunand)
\- Toulouse Mathematics Institute, France (Pr P. Besse)
2014
**Crop ontology curator. Bioversity International, Montpellier Office (France); 10 months**
Team: Crop Ontology project of the Generation Challenge Programme (E. Arnaud)
Internship:
2013
**Station Biologique de Roscoff, Marine Plants and Biomolecules, UMR 7139 UPMC/CNRS; 6 months**
2012
**Laboratory “Ecosystems, Biodiversity, Evolution”, UMR 6553 Rennes 1 University/CNRS; 3 months**
2011
**Laboratory of Plants Ecophysiological Responses to Environmental Stress, INRA Montpellier; 6 months**
2010
**Laboratory “Ecology Systematic Evolution”, Paris-Sud 11 University; 4 months**
Team: Photosynthesis, environment and adaptation (P. Streb & G. Cornic)
2004-2011
**Joseph Fourier Alpine Station, Alpine Botanical garden of Lautaret; Internship 2 months / year**
EDUCATION
==========
2013
**M.Sc. Degree: Integrative plant biology: Gene, Plant, Agro-system**
6 collaborating universities & Agrocampus Ouest (France)
*Major: Physiology/Metabolism and Eco-Physiology.*
2011
**BSc Degree: Functional Plant Biology**
Montpellier 2 University (France)
TEACHING and MENTORING
======================
**Supervision:**
PhD:
**2021-2022** - Abdou Rahmane Wade. Improved genome-based phenotypic predictions with a systems biology approach. (Co-doctoral advisor: Leopoldo Sanchez Rodriguez & Vincent Segura)
**2022-on going** - Alexandre Duplan. Improvement of pan-genomic knowledge and prediction of complex phenotypes by an integrative multi-omics approach. (Co-doctoral advisor: Leopoldo Sanchez Rodriguez & Stephane Maury)
PostDoc:
**2022** - Xabi Cazenave : Postdoc: 11 months
Internship:
**2023** - Alae-Eddine LEKCHIRI, Master degree, Rennes University
**2023** - Maya Doureradjam. Master degree, Montpellier University (France): 6 months
**2022** - Julien Desforges. Master degree, Orleans University (France): 4 months
**2018** - Claire Espérou. 4th year in mathematics and modelling engineering school of INSA, Toulouse (France): 3 months
**2017** - Sébastien Viudes. Master degree, Toulouse University (France): 2 months
**2016** - Merwann Selmani. 4th year in mathematics and modelling engineering school of INSA, Toulouse (France): 3 months
**2015** - Duchesse Lacour Mbadinga Mbadinga. BSc. Degree, Toulouse University (France): 6 months
Others:
**2019** - Caroline Laffray. Engineer: 1 year
**2018** - Charlotte Penouilh-Suzette. Engineer: 6 months
**Teaching:**
**2015 - 2017**: Toulouse University, biostatistics and biophysics at BSc. Degree, 70 h per year.
PROFESSIONAL SERVICES
=====================
International meeting organization committees of:
\- The [IX European Plant Science Retreat](http://epsr.net/), 20 - 23 June **2017**, Toulouse (France)
\- The [Workshop on Multivariate data integration using the R package mixOmics](http://mixomics.org/2016/05/12-14-sept-toulouse/), 12 - 14 September **2016**, Toulouse (France)
\- The [Workshop on Crop Ontology and Phenotyping Data Interoperability](https://sites.google.com/a/cgxchange.org/cropontologycommunity/), 31 March - 4 April **2014**, Montpellier (France)
Publications
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Multi-omics Data Integration in the Context of Plant Abiotic Stress SignalingPlant Abiotic Stress Signaling, 2642, Springer US, pp.295-318, 2023, Methods in Molecular Biology, ⟨10.1007/978-1-0716-3044-0_16⟩
Chapitre d'ouvrage
hal-04040408v1
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A powerful framework for an integrative study with heterogeneous omics data: from univariate statistics to multi-block analysisBriefings in Bioinformatics, 2021, 22 (3), pp.bbaa166. ⟨10.1093/bib/bbaa166⟩
Article dans une revue
hal-02921927v3
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An integrative Study Showing the Adaptation to Sub-Optimal Growth Conditions of Natural Populations of Arabidopsis thaliana: A Focus on Cell Wall ChangesCells, 2020, 9 (10), pp.2249. ⟨10.3390/cells9102249⟩
Article dans une revue
hal-02965604v1
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Phenotypic Trait Variation as a Response to Altitude-Related Constraints in Arabidopsis PopulationsFrontiers in Plant Science, 2019, 10, pp.430. ⟨10.3389/fpls.2019.00430⟩
Article dans une revue
hal-02115698v1
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Cell wall modifications of two Arabidopsis thaliana ecotypes, Col and Sha, in response to sub-optimal growth conditionsPlant Science, 2017, 263, pp.183-193. ⟨10.1016/j.plantsci.2017.07.015⟩
Article dans une revue
hal-03121655v1
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Contribution of an integrative study to the understanding of plant adaptation to their environment: A focus on plant cell walls.Cell Wall Days, Oct 2020, Toulouse, France
Communication dans un congrès
hal-03509280v1
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Arabidopsis thaliana as a model plant to study acclimation to sub-optimal growth conditions: An integrative study combining omics approaches reveals the importance of the cell wall.INPPO World Congress, Sep 2018, Padoue, Italy
Communication dans un congrès
hal-03509374v1
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Cell wall adaptation to sub-optimal growth conditions of natural population of Arabidopsis.11es Journées du Réseau Français des Parois, Jun 2017, Orléans, France
Communication dans un congrès
hal-03509390v1
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Analysis and integration of heterogeneous data from response to low temperature condition of two Arabidopsis thaliana ecotypesCOST FA1306, Workgroup 2, Feb 2016, Versailles, France
Communication dans un congrès
hal-03509455v1
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Phenotypic trait variation in genetically distincts Arabidopsis thaliana populations from the Pyrenees Mountains highlight acclimation to environmental constraints.Poster de conférence hal-03511709v1 |
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Analysis and integration of heterogeneous data from response to low temperature condition of two Arabidopsis thaliana ecotypesDay of the Doctoral School SEVAB, Mar 2016, Toulouse, France
Poster de conférence
hal-03511731v1
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Production and treatment of heterogeneous omics data in order to study the cell wall plasticity in various Pyrenean altitudinal A. thaliana ecotypesDay of the Doctoral School SEVAB, Mar 2015, Toulouse, France
Poster de conférence
hal-03511721v1
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