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Harold Duruflé - Research Scientist


 

RESEARCH EXPERIENCE

 

2021

Research Scientist: Integrative genomic prediction of complex phenotypes using system biology approach

- Integrated Biology for the Development of Tree and Forest Diversity Laboratory, UMR INRAE/ONF 0588

2017

PostDoc position: Develop the systems biology approach within the SUNRISE project; Temporary contract 3 years

- Laboratory of Plant-Microbe Interactions, UMR 2594/441 CNRS/INRA, Toulouse, France

- Team: Sunflower Genetics and Genomics (N. Langlade)

2014

PhD (3 years): “Production and treatment of heterogeneous Omics data in order to study the cell wall plasticity in A. thaliana ecotypes living at contrasted altitudinal level”; Temporary contract 3 years

- Plant Science Research Laboratory, UMR 5546 UPS/CNRS, Toulouse, France (Pr C. Dunand)

- Toulouse Mathematics Institute, France (Pr P. Besse / S. Déjean)

2014

Bioversity International, Montpellier Office (France); Temporary contract 10 months

Team: Crop Ontology project of the Generation Challenge Programme (E. Arnaud)

- Crop ontology curator

2013

Station Biologique de Roscoff, Marine Plants and Biomolecules, UMR 7139 UPMC/CNRS; Internship: 6 months

2012

Laboratory “Ecosystems, Biodiversity, Evolution”, UMR 6553 Rennes 1 University/CNRS; Internship: 3 months

2011

Laboratory of Plants Ecophysiological Responses to Environmental Stress, INRA Montpellier; Internship: 6 months

2010

Laboratory “Ecology Systematic Evolution”, Paris-Sud 11 University; Internship: 4 months

Team: Photosynthesis, environment and adaptation (P. Streb & G. Cornic)

2004-2011

Joseph Fourier Alpine Station, Alpine Botanical garden of Lautaret; Internship 2 months / year

 

 EDUCATION

 

2013

M.Sc. Degree: Integrative plant biology: Gene, Plant, Agro-system

6 collaborating universities & Agrocampus Ouest (France)

Major: Physiology/Metabolism and Eco-Physiology.

2011

BSc Degree: Functional Plant Biology

Montpellier 2 University (France)

 

TEACHING and MENTORING

 

2015 - 2017: Teaching at Toulouse University, biostatistics and biophysics at BSc. Degree, 70 h per year.

Supervision:

 2019 - Caroline Laffray : Engineer: 1 year

 2018 - Claire Espérou : 4th year in mathematics and modelling engineering school of INSA, Toulouse (France): 3 months

 2018 - Penouilh-Suzette Charlotte : Engineer: 6 months

 2017 - Viudes Sébastien: Master degree, Toulouse University (France): 2 months

 2016 - Selmani Merwann: 4th year in mathematics and modelling engineering school of INSA, Toulouse (France): 3 months

 2015 - Mbadinga Mbadinga Duchesse Lacour: BSc. Degree, Toulouse University (France): 6 months

 

PROFESSIONAL SERVICES

 International meeting organization committees of:

 - The IX European Plant Science Retreat, 20 - 23 June 2017, Toulouse (France)

 - The Workshop on Multivariate data integration using the R package mixOmics, 12 - 14 September 2016, Toulouse (France)

 - The Workshop on Crop Ontology and Phenotyping Data Interoperability, 31 March - 4 April 2014, Montpellier (France‎)

 


Journal articles15 documents

  • Thierry Balliau, Harold Duruflé, Nicolas Blanchet, Melisande Blein-Nicolas, Nicolas Langlade, et al.. Proteomic data from leaves of twenty-four sunflower genotypes under water deficit. OCL Oilseeds and fats crops and lipids, EDP, 2021, 28, pp.12. ⟨10.1051/ocl/2020074⟩. ⟨hal-03139476⟩
  • Harold Durufle, Philippe Ranocha, Thierry Balliau, Michel Zivy, Cécile Albenne, et al.. An integrative Study Showing the Adaptation to Sub-Optimal Growth Conditions of Natural Populations of Arabidopsis thaliana: A Focus on Cell Wall Changes. Cells, MDPI, 2020, 9 (10), pp.2249. ⟨10.3390/cells9102249⟩. ⟨hal-02965604⟩
  • Charlotte Penouilh-Suzette, Lise Pomies, Harold Durufle, Nicolas Blanchet, Fanny Bonnafous, et al.. RNA expression dataset of 384 sunflower hybrids in field condition. OCL Oilseeds and fats crops and lipids, EDP, 2020, 27, pp.36. ⟨10.1051/ocl/2020027⟩. ⟨hal-02912579⟩
  • Harold Duruflé, Merwann Selmani, Philippe Ranocha, Elisabeth Jamet, Christophe Dunand, et al.. A powerful framework for an integrative study with heterogeneous omics data: from univariate statistics to multi-block analysis. Briefings in Bioinformatics, Oxford University Press (OUP), 2020, ⟨10.1093/bib/bbaa166⟩. ⟨hal-02921927⟩
  • Louise Gody, Harold Durufle, Nicolas Blanchet, Clément Carré, Ludovic Legrand, et al.. Données transcriptomiques de feuilles de huit lignées de tournesol et de leurs 16 hybrides soumis à un stress hydrique. OCL Oilseeds and fats crops and lipids, EDP, 2020, 27, pp.48. ⟨10.1051/ocl/2020044⟩. ⟨hal-02974900⟩
  • Olivier Fernandez, Maria Urrutia, Thierry Berton, Stéphane Bernillon, Catherine Deborde, et al.. Metabolomic characterization of sunflower leaf allows discriminating genotype groups or stress levels with a minimal set of metabolic markers. Metabolomics, Springer Verlag, 2019, 15 (4), pp.56. ⟨10.1007/s11306-019-1515-4⟩. ⟨hal-02487236⟩
  • Harold Duruflé, Philippe Ranocha, Duchesse Lacour Mbadinga Mbadinga, Sébastien Déjean, Maxime Bonhomme, et al.. Phenotypic Trait Variation as a Response to Altitude-Related Constraints in Arabidopsis Populations. Frontiers in Plant Science, Frontiers, 2019, 10, pp.430. ⟨10.3389/fpls.2019.00430⟩. ⟨hal-02115698⟩
  • Harold Duruflé, Philippe Ranocha, Thierry Balliau, Christophe Dunand, Elisabeth Jamet. Transcriptomic and cell wall proteomic datasets of rosettes and floral stems from five Arabidopsis thaliana ecotypes grown at optimal or sub-optimal temperature. Data in Brief, Elsevier, 2019, 27, pp.104581. ⟨10.1016/j.dib.2019.104581⟩. ⟨hal-02938744⟩
  • Harold Duruflé, Cécile Albenne, Elisabeth Jamet, Christophe Dunand. Phenotyping and cell wall polysaccharide composition dataset of five arabidopsis ecotypes grown at optimal or sub-optimal temperatures. Data in Brief, Elsevier, 2019, 25, pp.104318. ⟨10.1016/j.dib.2019.104318⟩. ⟨hal-03121670⟩
  • Nicolas Blanchet, Pierre Casadebaig, Philippe Debaeke, Harold Duruflé, Louise Gody, et al.. Data describing the eco-physiological responses of twenty-four sunflower genotypes to water deficit. Data in Brief, Elsevier, 2018, 21, pp.1296-1301. ⟨10.1016/j.dib.2018.10.045⟩. ⟨hal-02625452⟩
  • Harold Duruflé, Hélène San Clemente, Thierry Balliau, Michel Zivy, Christophe Dunand, et al.. Cell wall proteome analysis of Arabidopsis thaliana mature stems. Proteomics, Wiley-VCH Verlag, 2017, 17 (8), pp.1-5. ⟨10.1002/pmic.201600449⟩. ⟨hal-01606770⟩
  • Harold Duruflé, Vincent Herve, Philippe Ranocha, Thierry Balliau, Michel Zivy, et al.. Cell wall modifications of two Arabidopsis thaliana ecotypes, Col and Sha, in response to sub-optimal growth conditions: An integrative study. Plant Science, Elsevier, 2017, 263, pp.183-193. ⟨10.1016/j.plantsci.2017.07.015⟩. ⟨hal-03121655⟩
  • Harold Duruflé, Vincent Herve, Thierry Balliau, Michel Zivy, Christophe Dunand, et al.. Proline hydroxylation in cell wall proteins: is it yet possible to define rules?. Frontiers in Plant Science, Frontiers, 2017, 8, ⟨10.3389/fpls.2017.01802⟩. ⟨hal-02620851⟩
  • Andrés Ritter, Léa Cabioch, Loraine Brillet-Guéguen, Erwan Corre, Audrey Cosse, et al.. Herbivore-induced chemical and molecular responses of the kelps Laminaria digitata and Lessonia spicata. PLoS ONE, Public Library of Science, 2017, 12 (3), pp.e0173315. ⟨10.1371/journal.pone.0173315.s011⟩. ⟨hal-01587420⟩
  • Vincent Hervé, Harold Duruflé, Hélène San Clemente, Cécile Albenne, Thierry Balliau, et al.. An enlarged cell wall proteome of Arabidopsis thaliana rosettes.. Proteomics, Wiley-VCH Verlag, 2016, 16 (24), pp.3183-3187. ⟨10.1002/pmic.201600290⟩. ⟨pasteur-01421109⟩

Conference papers1 document

  • Harold Duruflé, Thierry Balliau, Nicolas Blanchet, Melisande Blein-Nicolas, A Chaubet, et al.. Duruflé H, Balliau T, Blanchet N, Blein-Nicolas M, Chaubet A, Mangin B, Maury P, Zivy M, Langlade N. Plant and Animal Genome XXVII, Jan 2019, San Diego, United States. ⟨hal-02391988⟩

Preprints, Working Papers, ...2 documents

  • Thierry Balliau, Harold Duruflé, Nicolas Blanchet, Melisande Blein-Nicolas, Nicolas B. Langlade, et al.. Proteomic data from leaves of twenty-four sunflower genotypes under water deficit. 2020. ⟨hal-02544815⟩
  • Harold Duruflé, Merwann Selmani, Philippe Ranocha, Elisabeth Jamet, Christophe Dunand, et al.. A powerful framework for an integrative study with heterogeneous omics data: from univariate statistics to multi-block analysis. 2018. ⟨hal-01826110⟩

Theses1 document

  • Harold Duruflé. Production et traitement de données omiques hétérogènes en vue de l'étude de la plasticité de la paroi chez des écotypes de la plante modèle Arabidopsis thaliana provenant d'altitudes contrastées. Biologie végétale. Université Paul Sabatier - Toulouse III, 2017. Français. ⟨NNT : 2017TOU30219⟩. ⟨tel-02004363⟩