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The foundation and architecture of precision medicine in neurology and psychiatry
Harald Hampel
,
Peng Gao
,
Jeffrey Cummings
,
Nicola Toschi
,
Paul M Thompson
Article dans une revue
hal-03938895v1
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Evaluation of major national dementia policies and health‐care system preparedness for early medical action and implementation
Harald Hampel
,
Andrea Vergallo
,
Takeshi Iwatsubo
,
Min Cho
,
Kiyoshi Kurokawa
Alzheimer's & Dementia : the Journal of the Alzheimer's Association, 2022, 18 (10), pp.1993-2002. ⟨10.1002/alz.12655⟩
Article dans une revue
hal-03942260v1
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Menopause hormone therapy significantly alters pathophysiological biomarkers of Alzheimer's disease
Herman Depypere
,
Andrea Vergallo
,
Pablo Lemercier
,
Simone Lista
,
Andrea Benedet
Article dans une revue
hal-03942258v1
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State‐of‐the‐art of lumbar puncture and its place in the journey of patients with Alzheimer's disease
Harald Hampel
,
Leslie M Shaw
,
Paul Aisen
,
Christopher Chen
,
Alberto Lleó
Alzheimer's & Dementia : the Journal of the Alzheimer's Association, 2022, 18 (1), pp.159-177. ⟨10.1002/alz.12372⟩
Article dans une revue
hal-03942259v1
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Designing the next-generation clinical care pathway for Alzheimer’s disease
Harald Hampel
,
Rhoda Au
,
Soeren Mattke
,
Wiesje M van der Flier
,
Paul Aisen
Article dans une revue
hal-03942256v1
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New insights into the genetic etiology of Alzheimer's disease and related dementias
Celine Bellenguez
,
Fahri Kucukali
,
Iris E. Jansen
,
Luca Kleineidam
,
Sonia Moreno-Grau
Article dans une revue
hal-03668928v1
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The β-Secretase BACE1 in Alzheimer’s Disease
Harald Hampel
,
Robert Vassar
,
Bart de Strooper
,
John Hardy
,
Michael Willem
Article dans une revue
hal-03197728v1
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Common variants in Alzheimer's disease and risk stratification by polygenic risk scores
Itziar de Rojas
,
Sonia Moreno-Grau
,
Niccolo Tesi
,
Benjamin Grenier-Boley
,
Victor Andrade
Article dans une revue
hal-03287265v1
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Association of plasma Aβ40/Aβ42 ratio and brain Aβ accumulation: testing a whole-brain PLS-VIP approach in individuals at risk of Alzheimer's disease
Pablo Lemercier
,
Andrea Vergallo
,
Simone Lista
,
Henrik Zetterberg
,
Kaj Blennow
Article dans une revue
hal-03391168v1
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The Amyloid-β Pathway in Alzheimer’s Disease
Harald Hampel
,
John Hardy
,
Kaj Blennow
,
Christopher Chen
,
George Perry
Article dans une revue
hal-03942257v1
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Aptamarker prediction of brain amyloid-β status in cognitively normal individuals at risk for Alzheimer’s disease
Gregory Penner
,
Soizic Lecocq
,
Anaëlle Chopin
,
Ximena Vedoya
,
Simone Lista
Article dans une revue
hal-03212567v1
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MiRNA-15b and miRNA-125b are associated with regional Aβ-PET and FDG-PET uptake in cognitively normal individuals with subjective memory complaints
Andrea Vergallo
,
Simone Lista
,
Yuhai Zhao
,
Pablo Lemercier
,
Stefan Teipel
Article dans une revue
hal-03125818v1
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Partial Volume Correction Increases the Sensitivity of 18F-Florbetapir-Positron Emission Tomography for the Detection of Early Stage Amyloidosis
Stefan J Teipel
,
Martin Dyrba
,
Andrea Vergallo
,
Simone Lista
,
Marie Odile Habert
Article dans une revue
hal-03521540v1
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Progress regarding the context-of-use of tau as biomarker of Alzheimer’s disease and other neurodegenerative diseases
Nicole Campese
,
Giovanni Palermo
,
Claudia Del Gamba
,
Maria Francesca Beatino
,
Alessandro Galgani
Article dans une revue
hal-03138524v1
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Age and sex impact plasma NFL and t-Tau trajectories in individuals with subjective memory complaints: a 3-year follow-up study
Filippo Baldacci
,
Simone Lista
,
Maria Laura Manca
,
Patrizia A Chiesa
,
Enrica Cavedo
Article dans une revue
hal-03272059v1
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Accuracy of MRI Classification Algorithms in a Tertiary Memory Center Clinical Routine Cohort
Alexandre Morin
,
Jorge Samper-González
,
Anne Bertrand
,
Sebastian Ströer
,
Didier Dormont
Article dans une revue
hal-02511532v1
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Different Clinical Contexts of Use of Blood Neurofilament Light Chain Protein in the Spectrum of Neurodegenerative Diseases
Giovanni Palermo
,
Sonia Mazzucchi
,
Alessandra Della Vecchia
,
Gabriele Siciliano
,
Ubaldo Bonuccelli
Article dans une revue
hal-03385896v1
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Association of plasma YKL-40 with brain amyloid-β levels, memory performance, and sex in subjective memory complainers
Andrea Vergallo
,
Simone Lista
,
Pablo Lemercier
,
Patrizia A. Chiesa
,
Henrik Zetterberg
Article dans une revue
hal-03491473v1
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A Path Toward Precision Medicine for Neuroinflammatory Mechanisms in Alzheimer's Disease
Harald Hampel
,
Filippo Caraci
,
A. Claudio Cuello
,
Giuseppe Mario Caruso
,
Robert Nisticò
Article dans une revue
hal-02570114v1
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Resting-state posterior alpha rhythms are abnormal in subjective memory complaint seniors with preclinical Alzheimer's neuropathology and high education level: the INSIGHT-preAD study
Claudio Babiloni
,
Susanna Lopez
,
Claudio del Percio
,
Giuseppe Noce
,
Maria Teresa Pascarelli
Article dans une revue
hal-03006214v1
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Brain Aβ load association and sexual dimorphism of plasma BACE1 concentrations in cognitively normal individuals at risk for AD
Andrea Vergallo
,
Marion Houot
,
Enrica Cavedo
,
Pablo Lemercier
,
Eugeen Vanmechelen
Article dans une revue
hal-03489074v1
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Biomarker-guided clustering of Alzheimer's disease clinical syndromes
Nicola Toschi
,
Simone Lista
,
Filippo Baldacci
,
Enrica Cavedo
,
Henrik Zetterberg
Article dans une revue
hal-03488653v1
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Applicability of in vivo staging of regional amyloid burden in a cognitively normal cohort with subjective memory complaints: the INSIGHT-preAD study
Fatemah A Sakr
,
Michel J Grothe
,
Enrica Cavedo
,
Irina Jelistratova
,
Marie-Odile Habert
Article dans une revue
hal-02006123v1
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Differential default mode network trajectories in asymptomatic individuals at risk for Alzheimer's disease
Patrizia A Chiesa
,
Enrica Cavedo
,
Andrea Vergallo
,
Simone Lista
,
Marie-Claude Potier
Article dans une revue
hal-02368904v1
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Plasma amyloid β 40/42 ratio predicts cerebral amyloidosis in cognitively normal individuals at risk for Alzheimer's disease
Andrea Vergallo
,
Lucile Mégret
,
Simone Lista
,
Enrica Cavedo
,
Henrik Zetterberg
Article dans une revue
hal-03484725v1
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Time for the systems-level integration of aging: Resilience enhancing strategies to prevent Alzheimer’s disease
Harald Hampel
,
Simone Lista
,
Christian Neri
,
Andrea Vergallo
Article dans une revue
hal-03488187v1
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Reduction of recruitment costs in preclinical AD trials. Validation of automatic pre-screening algorithm for brain amyloidosis
Manon Ansart
,
Stéphane Epelbaum
,
Geoffroy Gagliardi
,
Olivier Colliot
,
Didier Dormont
Article dans une revue
hal-01964942v2
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Biomarker-Drug and Liquid Biopsy Co-development for Disease Staging and Targeted Therapy: Cornerstones for Alzheimer’s Precision Medicine and Pharmacology
Harald Hampel
,
Edward J Goetzl
,
Dimitrios Kapogiannis
,
Simone Lista
,
Andrea Vergallo
Article dans une revue
hal-02095292v1
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Biomarker-based prognosis for people with mild cognitive impairment (ABIDE): a modelling study
Ingrid S van Maurik
,
Stephanie J Vos
,
Isabelle Bos
,
Femke H Bouwman
,
Charlotte Teunissen
Article dans une revue
inserm-02747461v1
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No association of cortical amyloid load and EEG connectivity in older people with subjective memory complaints
Stefan Teipel
,
Hovagim Bakardjian
,
Gabriel Gonzalez-Escamilla
,
Enrica Cavedo
,
Sarah Weschke
Article dans une revue
hal-01738143v1
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Revolution of Alzheimer Precision Neurology. Passageway of Systems Biology and Neurophysiology
Harald Hampel
,
Nicola Toschi
,
Claudio Babiloni
,
Filippo Baldacci
,
Keith L Black
Article dans une revue
hal-01910402v1
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Blood-based biomarkers for Alzheimer disease: mapping the road to the clinic
Harald Hampel
,
Sid O'Bryant
,
José L Molinuevo
,
Henrik Zetterberg
,
Colin L. Masters
Article dans une revue
hal-01972372v1
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Evaluation of amyloid status in a cohort of elderly individuals with memory complaints: validation of the method of quantification and determination of positivity thresholds
Marie-Odile Habert
,
Hugo Bertin
,
Mickael Labit
,
Mamadou Diallo
,
Sullivan Marie
Article dans une revue
hal-01716483v1
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Cognitive and neuroimaging features and brain β-amyloidosis in individuals at risk of Alzheimer's disease (INSIGHT-preAD): a longitudinal observational study
Bruno Dubois
,
Stéphane Epelbaum
,
Francis Nyasse
,
Hovagim Bakardjian
,
Geoffroy Gagliardi
Article dans une revue
hal-01777834v1
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Current state of Alzheimer’s fluid biomarkers
José Luis Molinuevo
,
Scott Ayton
,
Richard Batrla
,
Martin M Bednar
,
Tobias Bittner
Article dans une revue
hal-01960281v1
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Gray Matter Network Disruptions and Regional Amyloid Beta in Cognitively Normal Adults
Mara ten Kate
,
Pieter Jelle Visser
,
Hovagim Bakardjian
,
Frederik Barkhof
,
Sietske A.M. Sikkes
Article dans une revue
hal-01757310v1
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Analysis of shared heritability in common disorders of the brain
Verneri Anttila
,
Brenda Sullivan
,
Hilary Finucane
,
Walter Walters
,
Jose Bras
Article dans une revue
cea-01870483v1
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Preclinical effects of APOE ε4 on cerebrospinal fluid Aβ42 concentrations
Ronald Lautner
,
Philip S Insel
,
Tobias Skillbäck
,
Bob Olsson
,
Mikael Landén
Article dans une revue
hal-01629381v1
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Two-level diagnostic classification using cerebrospinal fluid YKL-40 in Alzheimer's disease
Filippo Baldacci
,
Nicola Toschi
,
Simone Lista
,
Henrik Zetterberg
,
Kaj Blennow
Article dans une revue
hal-01496140v1
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Reduced basal forebrain atrophy progression in a randomized Donepezil trial in prodromal Alzheimer's disease
Enrica Cavedo
,
Michel J Grothe
,
Olivier Colliot
,
Simone Lista
,
Marie Chupin
Article dans une revue
hal-01589622v1
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Preclinical Alzheimer's disease: a systematic review of the cohorts underlying the concept
Stéphane Epelbaum
,
Rémy Genthon
,
Enrica Cavedo
,
Marie Habert
,
Foudil Lamari
Article dans une revue
hal-01672859v1
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The frequency and influence of dementia risk factors in prodromal Alzheimer's disease
Isabelle Bos
,
Stephanie Vos
,
Lutz Frölich
,
Johannes Kornhuber
,
Jens Wiltfang
Article dans une revue
hal-03623839v1
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Amyloidosis and neurodegeneration result in distinct structural connectivity patterns in mild cognitive impairment
Thomas Jacquemont
,
Fabrizio de Vico Fallani
,
Anne Bertrand
,
Stéphane Epelbaum
,
Alexandre Routier
Article dans une revue
hal-01518785v1
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A Precision Medicine Initiative for Alzheimer's disease: the road ahead to biomarker-guided integrative disease modeling.
Harald Hampel
,
Sid O’bryant
,
Stanley Durrleman
,
Erfan Younesi
,
Katrine Rojkova
Climacteric, 2017, 20 (2), pp.107-118
Article dans une revue
hal-01566281v1
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Free and Cued Selective Reminding Test – accuracy for the differential diagnosis of Alzheimer's and neurodegenerative diseases: A large-scale biomarker-characterized monocenter cohort study (ClinAD)
Stéphane Epelbaum
,
Marc Teichmann
,
Dalila Samri
,
Marcel Levy Nogueira
,
Harald Hampel
Article dans une revue
hal-01672862v1
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Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
Rebecca Sims
,
Sven van Der Lee
,
Adam Naj
,
Céline Bellenguez
,
Nandini Badarinarayan
Article dans une revue
inserm-02466466v1
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Revolution of Resting-State Functional Neuroimaging Genetics in Alzheimer’s Disease
Patrizia A. Chiesa
,
Enrica Cavedo
,
Simone Lista
,
Paul M Thompson
,
Harald Hampel
Article dans une revue
hal-01560182v1
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Reduced Regional Cortical Thickness Rate of Change in Donepezil-Treated Subjects With Suspected Prodromal Alzheimer’s Disease
Enrica Cavedo
,
Bruno Dubois
,
Olivier Colliot
,
Simone Lista
,
Bernard Croisile
Article dans une revue
hal-01388951v1
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Predictors of cognitive decline and treatment response in a clinical trial on suspected prodromal Alzheimer's disease
Stefan J Teipel
,
Enrica Cavedo
,
Michel J Grothe
,
Simone Lista
,
Samantha Galluzzi
Article dans une revue
hal-01372417v1
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Apolipoprotein E-dependent load of white matter hyperintensities in Alzheimer's disease: a voxel-based lesion mapping study
Katrin Morgen
,
Michael Schneider
,
Lutz Frölich
,
Heike Tost
,
Michael M. Plichta
Article dans une revue
hal-01256015v1
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Donepezil decreases annual rate of hippocampal atrophy in suspected prodromal Alzheimer's disease
Bruno Dubois
,
Marie Chupin
,
Harald Hampel
,
Simone Lista
,
Enrica Cavedo
Article dans une revue
hal-01249861v1
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Excess of rare coding variants in PLD3 in late-but not early-onset Alzheimer's disease
Eva C Schulte
,
Alexander Kurz
,
Panagiotis Alexopoulos
,
Harald Hampel
,
Annette Peters
Article dans une revue
hal-01120238v1
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Comparing biological markers of Alzheimer's disease across blood fraction and platforms: Comparing apples to oranges
Sid E. O'Bryant
,
Simone Lista
,
Robert A. Rissman
,
Melissa Edwards
,
Fan Zhang
Article dans une revue
hal-01250140v1
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Perspective on future role of biological markers in clinical therapy trials of Alzheimer's disease: a long-range point of view beyond 2020
Harald Hampel
,
Simone Lista
,
Stefan J Teipel
,
Francesco Garaci
,
Robert Nisticò
Biochemical Pharmacology, 2014, pp.426-49
Article dans une revue
hal-01098832v1
|
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The road ahead to cure Alzheimer’s disease: development of biological markers and neuroimaging methods for prevention trials across all stages and target populations
Enrica Cavedo
,
Simone Lista
,
Zaven S Khachaturian
,
Paul S Aisen
,
Philippe Amouyel
Article dans une revue
hal-01098836v1
|
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Validation of AclarusDx™, a blood-based transcriptomic signature for the diagnosis of Alzheimer's disease.
Pascale Fehlbaum-Beurdeley
,
Olivier Sol
,
Laurent Désiré
,
Jacques Touchon
,
Thierry Dantoine
Article dans une revue
hal-01325482v1
|
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Validation of AclarusDx™, a blood-based transcriptomic signature for the diagnosis of Alzheimer's disease.
Pascale Fehlbaum-Beurdeley
,
Olivier Sol
,
Laurent Désiré
,
Jacques Touchon
,
Thierry Dantoine
Article dans une revue
hal-00727243v1
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Using support vector machines with multiple indices of diffusion for automated classification of mild cognitive impairment.
Laurence O'Dwyer
,
Franck Lamberton
,
Arun L W Bokde
,
Michael Ewers
,
Yetunde O Faluyi
PLoS ONE, 2012, 7, pp.e32441
Article dans une revue
hal-01164652v1
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Sexual dimorphism in healthy aging and mild cognitive impairment: a DTI study.
Laurence O'Dwyer
,
Franck Lamberton
,
Arun L W Bokde
,
Michael Ewers
,
Yetunde O Faluyi
PLoS ONE, 2011, 7 (7), pp.e37021
Article dans une revue
hal-01164673v1
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Multiple indices of diffusion identifies white matter damage in mild cognitive impairment and Alzheimer's disease.
Laurence O'Dwyer
,
Franck Lamberton
,
Arun L W Bokde
,
Michael Ewers
,
Yetunde O Faluyi
PLoS ONE, 2010, 6 (6), pp.e21745
Article dans une revue
hal-01157540v1
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White matter hyperintensities and medial temporal lobe atrophy in clinical subtypes of mild cognitive impairment: the DESCRIPA study
Laura van de Pol
,
Frans Verhey
,
Giovanni Frisoni
,
Magda Tsolaki
,
Panagiota Papapostoulou
Article dans une revue
hal-00552719v1
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Blood-based Biomarkers of Microvascular Pathology in Alzheimer's disease
Michael Ewers
,
Michelle M. Mielke
,
Harald Hampel
Article dans une revue
hal-00547642v1
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Validation of Alzheimer's disease CSF and Plasma Biological Markers The Multi-Center Reliability Study of the Pilot European Alzheimer's Disease Neuroimaging Initiative (E-ADNI)
Katharina Buerger
,
Giovanni B. Frisoni
,
Olga Uspenskaya
,
Michael Ewers
,
Henrik Zetterberg
Article dans une revue
hal-00510618v1
|
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Total and Phosphorylated Tau Protein as Biological Markers of Alzheimer's Disease
Harald Hampel
,
Kaj Blennow
,
Leslie M. Shaw
,
Yvonne C. Hoessler
,
Henrik Zetterberg
Article dans une revue
hal-00547645v1
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