Gulnara Yusupova

Documents

Publications

	Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents Jidong Zhang , Christine Lair , Christine Roubert , Kwame Amaning , María Belén Barrio Cell, 2023, 186 (5), pp.1013-1025.e24. ⟨10.1016/j.cell.2023.01.043⟩ Article dans une revue hal-04266217v1
	mRNA reading frame maintenance during eukaryotic ribosome translocation Nemanja Milicevic , Lasse Jenner , Alexander Myasnikov , Marat Yusupov , Gulnara Yusupova Nature, In press, ⟨10.1038/s41586-023-06780-4⟩ Article dans une revue hal-04323477v1
	E-site drug specificity of the human pathogen Candida albicans ribosome Yury Zgadzay , Olga Kolosova , Artem Stetsenko , Cheng Wu , David Bruchlen Science Advances , 2022, 8 (21), pp.eabn1062. ⟨10.1126/sciadv.abn1062⟩ Article dans une revue hal-03813407v1
	A Path to the Atomic-Resolution Structures of Prokaryotic and Eukaryotic Ribosomes Gulnara Yusupova , Marat Yusupov Биохимия / Biochemistry, 2021, 86 (8), pp.926-941. ⟨10.1134/S0006297921080046⟩ Article dans une revue hal-03365744v1
	Accuracy mechanism of eukaryotic ribosome translocation Muminjon Djumagulov , Natalia Demeshkina , Lasse Jenner , Alexey Rozov , Marat Yusupov Nature, 2021, 600 (7889), pp.543-546. ⟨10.1038/s41586-021-04131-9⟩ Article dans une revue hal-03800932v1
	Inhibition of the Eukaryotic 80S Ribosome as a Potential Anticancer Therapy: A Structural Perspective Gulnara Yusupova , Simone Pellegrino , Salvatore Terrosu , Marat Yusupov Cancers, 2021, 13, ⟨10.3390/cancers13174392⟩ Article dans une revue hal-03372921v1
	Mechanism of ribosome shutdown by RsfS in Staphylococcus aureus revealed by integrative structural biology approach Iskander Khusainov , Bulat Fatkhullin , Simone Pellegrino , Aydar Bikmullin , Wen-Ti Liu Nature Communications, 2020, 11 (1), pp.1656. ⟨10.1038/s41467-020-15517-0⟩ Article dans une revue inserm-02649160v1
	Cryo‐EM structure of the ribosome functional complex of the human pathogen Staphylococcus aureus at 3.2 Å resolution Alexander Golubev , Bulat Fatkhullin , Iskander Khusainov , Lasse Jenner , Azat Gabdulkhakov FEBS Letters, 2020, 594 (21), pp.3551 - 3567. ⟨10.1002/1873-3468.13915⟩ Article dans une revue hal-03373743v1
	Posttranslational modification of Elongation Factor P from Staphylococcus aureus Gulnara Yusupova , Alexander Golubev , Luc Negroni , Filipp Krasnovid , Shamil Validov FEBS Open Bio, 2020, 10 (7), pp.1342-1347. ⟨10.1002/2211-5463.12901⟩ Article dans une revue hal-02997686v1
	The multiple flavors of GoU pairs in RNA Eric Westhof , Marat M. Yusupov , Gulnara Yusupova Journal of Molecular Recognition, 2019, pp.e2782. ⟨10.1002/jmr.2782⟩ Article dans une revue hal-02361230v1
	Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome Gulnara Yusupova , Simone Pellegrino , Mélanie Meyer , Zef Könst , Mikael Holm Nucleic Acids Research, 2019, 47 (6), pp.3223-3232. ⟨10.1093/nar/gkz053⟩ Article dans une revue hal-03365753v1
	Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome Simone Pellegrino , Mélanie Meyer , Zef Könst , Mikael Holm , Vamsee Voora Nucleic Acids Research, 2019, 47 (6), pp.3223-3232. ⟨10.1093/nar/gkz053⟩ Article dans une revue hal-03659840v1
	Importance of potassium ions for ribosome structure and function revealed by long-wavelength X-ray diffraction Alexey Rozov , Iskander Khusainov , Kamel El Omari , Ramona Duman , Vitaliy Mykhaylyk Nature Communications, 2019, 10 (1), pp.2519. ⟨10.1038/s41467-019-10409-4⟩ Article dans une revue hal-03659834v1
	The Amaryllidaceae Alkaloid Haemanthamine Binds the Eukaryotic Ribosome to Repress Cancer Cell Growth Simone Pellegrino , Mélanie Meyer , Christiane Zorbas , Soumaya Bouchta , Kritika Saraf Structure, 2018, 26 (3), pp.416-425.e4. ⟨10.1016/j.str.2018.01.009⟩ Article dans une revue hal-03661103v1
	Tautomeric G•U pairs within the molecular ribosomal grip and fidelity of decoding in bacteria Alexey Rozov , Philippe Wolff , Henri Grosjean , Marat Yusupov , Gulnara Yusupova Nucleic Acids Research, 2018, 46 (14), pp.7425-7435. ⟨10.1093/nar/gky547⟩ Article dans une revue hal-03659841v1
	Structure of the 70S ribosome from human pathogen Staphylococcus aureus Iskander Khusainov , Quentin Vicens , Anthony Bochler , François Grosse , Alexander G. Myasnikov Nucleic Acids Research, 2017, 45 (2), pp.1026-1026. ⟨10.1093/nar/gkw1126⟩ Article dans une revue hal-02171293v1
	Aminoglycoside interactions and impacts on the eukaryotic ribosome Gulnara Yusupova , Irina Prokhorova , Roger Altman , Muminjon Djumagulov , Jaya Shrestha Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (51), pp.E10899-E10908. ⟨10.1073/pnas.1715501114⟩ Article dans une revue hal-03365761v1
	Crystal structure of eukaryotic ribosome and its complexes with inhibitors Gulnara Yusupova , Marat Yusupov Philosophical Transactions of the Royal Society B: Biological Sciences, 2017, 372 (1716), pp.20160184. ⟨10.1098/rstb.2016.0184⟩ Article dans une revue hal-03661123v1
	Inhibition of Eukaryotic Translation by the Antitumor Natural Product Agelastatin A Brandon Mcclary , Boris Zinshteyn , Mélanie Meyer , Morgan Jouanneau , Simone Pellegrino Cell Chemical Biology, 2017, 24 (5), pp.605-613.e5. ⟨10.1016/j.chembiol.2017.04.006⟩ Article dans une revue hal-03661121v1
	Structures and dynamics of hibernating ribosomes from Staphylococcus aureus mediated by intermolecular interactions of HPF Iskander Khusainov , Quentin Vicens , Rustam Ayupov , Konstantin Usachev , Alexander Myasnikov EMBO Journal, 2017, 36 (14), pp.2073-2087. ⟨10.15252/embj.201696105⟩ Article dans une revue hal-03661109v1
	Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides Zef Könst , Anne Szklarski , Simone Pellegrino , Sharon Michalak , Mélanie Meyer Nature Chemistry, 2017, 9 (11), pp.1140-1149. ⟨10.1038/nchem.2800⟩ Article dans une revue hal-03659848v1
	Amicoumacin A induces cancer cell death by targeting the eukaryotic ribosome Irina Prokhorova , Kseniya Akulich , Desislava Makeeva , Ilya Osterman , Dmitry Skvortsov Scientific Reports, 2016, 6 (1), pp.27720. ⟨10.1038/srep27720⟩ Article dans une revue hal-03661134v1
	Crystal Structure of Hypusine-Containing Translation Factor eIF5A Bound to a Rotated Eukaryotic Ribosome Sergey Melnikov , Justine Mailliot , Byung-Sik Shin , Lukas Rigger , Gulnara Yusupova Journal of Molecular Biology, 2016, 428 (18), pp.3570-3576. ⟨10.1016/j.jmb.2016.05.011⟩ Article dans une revue hal-03661136v1
	Eukaryotic Ribosome as a Target for Cardiovascular Disease Simone P Pellegrino , Gulnara Yusupova Cell Chemical Biology, 2016, 17 (23), pp.1319-1321. ⟨10.1016/j.chembiol.2016.11.004⟩ Article dans une revue inserm-01415698v1
	Molecular insights into protein synthesis with proline residues Sergey Melnikov , Justine Mailliot , Lukas Rigger , Sandro Neuner , Byung‐sik Shin EMBO Reports, 2016, 17 (12), pp.1776-1784. ⟨10.15252/embr.201642943⟩ Article dans une revue hal-03661132v1
	Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code Alexey Rozov , Natalia Demeshkina , Iskander Khusainov , Eric Westhof , Marat M. Yusupov Nature Communications, 2016, 7 (1), pp.10457. ⟨10.1038/ncomms10457⟩ Article dans une revue hal-02294521v1
	Crystal Structures of the uL3 Mutant Ribosome: Illustration of the Importance of Ribosomal Proteins for Translation Efficiency Justine Mailliot , Nicolas Garreau de Loubresse , Gulnara Yusupova , Arturas Meskauskas , Jonathan Dinman Journal of Molecular Biology, 2016, 428 (10), pp.2195-2202. ⟨10.1016/j.jmb.2016.02.013⟩ Article dans une revue hal-03661143v1
	New Structural Insights into Translational Miscoding Alexey Rozov , Natalia Demeshkina , Eric Westhof , Marat M. Yusupov , Gulnara Yusupova Trends in Biochemical Sciences, 2016, 41 (9), pp.798-814. ⟨10.1016/j.tibs.2016.06.001⟩ Article dans une revue hal-02294531v1
	The ribosome prohibits the G•U wobble geometry at the first position of the codon–anticodon helix Alexey Rozov , Eric Westhof , Marat M. Yusupov , Gulnara Yusupova Nucleic Acids Research, 2016, 44 (13), pp.6434-41. ⟨10.1093/nar/gkw431⟩ Article dans une revue hal-02294675v1
	Insights into the origin of the nuclear localization signals in conserved ribosomal proteins Sergey Melnikov , Adam Ben-Shem , Gulnara Yusupova , Marat Yusupov Nature Communications, 2015, 6 (1), pp.7382. ⟨10.1038/ncomms8382⟩ Article dans une revue hal-03661149v1
	Ribosome biochemistry in crystal structure determination Gulnara Yusupova , Marat Yusupov RNA, 2015, 21 (4), pp.771-773. ⟨10.1261/rna.050039.115⟩ Article dans une revue hal-03661153v1
	Structural insights into the translational infidelity mechanism Alexey Rozov , Natalia Demeshkina , Eric Westhof , Marat Yusupov , Gulnara Yusupova Nature Communications, 2015, 6 (1), pp.7251. ⟨10.1038/ncomms8251⟩ Article dans une revue hal-03661150v1
	Recognition of Watson-Crick base pairs: constraints and limits due to geometric selection and tautomerism Eric Westhof , Marat Yusupov , Gulnara Yusupova F1000Prime Reports, 2014, 6, ⟨10.12703/P6-19⟩ Article dans une revue hal-03661156v1
	Structural basis for the inhibition of the eukaryotic ribosome Nicolas Garreau de Loubresse , Irina Prokhorova , Wolf Holtkamp , Marina Rodnina , Gulnara Yusupova Nature, 2014, 513 (7519), pp.517-522. ⟨10.1038/nature13737⟩ Article dans une revue hal-03661154v1
	High-Resolution Structure of the Eukaryotic 80S Ribosome Gulnara Yusupova , Marat Yusupov Annual Review of Biochemistry, 2014, 83 (1), pp.467-486. ⟨10.1146/annurev-biochem-060713-035445⟩ Article dans une revue hal-03661159v1
	Structural basis for potent inhibitory activity of the antibiotic tigecycline during protein synthesis Lasse Jenner , Agata Starosta , Daniel Terry , Aleksandra Mikolajka , Liudmila Filonava Proceedings of the National Academy of Sciences of the United States of America, 2013, 110 (10), pp.3812-3816. ⟨10.1073/pnas.1216691110⟩ Article dans une revue hal-03661163v1
	New structural insights into the decoding mechanism: Translation infidelity via a G·U pair with Watson-Crick geometry Natalia Demeshkina , Lasse Jenner , Eric Westhof , Marat Yusupov , Gulnara Yusupova FEBS Letters, 2013, 587 (13), pp.1848-1857. ⟨10.1016/j.febslet.2013.05.009⟩ Article dans une revue hal-03661161v1
	One core, two shells: bacterial and eukaryotic ribosomes Sergey Melnikov , Adam Ben-Shem , Nicolas Garreau de Loubresse , Lasse Jenner , Gulnara Yusupova Nature Structural and Molecular Biology, 2012, 19 (6), pp.560-567. ⟨10.1038/nsmb.2313⟩ Article dans une revue hal-03661166v1
	A new understanding of the decoding principle on the ribosome Natalia Demeshkina , Lasse Jenner , Eric Westhof , Marat Yusupov , Gulnara Yusupova Nature, 2012, 484 (7393), pp.256-259. ⟨10.1038/nature10913⟩ Article dans une revue hal-03661168v1
	Crystal structure of the 80S yeast ribosome Lasse Jenner , Sergey Melnikov , Nicolas Garreau de Loubresse , Adam Ben-Shem , Madina Iskakova Current Opinion in Structural Biology, 2012, 22 (6), pp.759-767. ⟨10.1016/j.sbi.2012.07.013⟩ Article dans une revue hal-03661164v1
	The Structure of the Eukaryotic Ribosome at 3.0 Å Resolution Adam Ben-Shem , Nicolas Garreau de Loubresse , Sergey Melnikov , Lasse Jenner , Gulnara Yusupova Science, 2011, 334 (6062), pp.1524-1529. ⟨10.1126/science.1212642⟩ Article dans une revue hal-03661170v1
	Interactions of the ribosome with mRNA and tRNA Natalia Demeshkina , Lasse Jenner , Gulnara Yusupova , Marat Yusupov Current Opinion in Structural Biology, 2010, 20 (3), pp.325-332. ⟨10.1016/j.sbi.2010.03.002⟩ Article dans une revue hal-03661179v1
	Structural aspects of messenger RNA reading frame maintenance by the ribosome Lasse Jenner , Natalia Demeshkina , Gulnara Yusupova , Marat Yusupov Nature Structural and Molecular Biology, 2010, 17 (5), pp.555-560. ⟨10.1038/nsmb.1790⟩ Article dans une revue hal-03661176v1
	Structural rearrangements of the ribosome at the tRNA proofreading step Lasse Jenner , Natalia Demeshkina , Gulnara Yusupova , Marat Yusupov Nature Structural and Molecular Biology, 2010, 17 (9), pp.1072-1078. ⟨10.1038/nsmb.1880⟩ Article dans une revue hal-03661174v1
	Crystal Structure of the Eukaryotic Ribosome Adam Ben-Shem , Lasse Jenner , Gulnara Yusupova , Marat Yusupov Science, 2010, 330 (6008), pp.1203-1209. ⟨10.1126/science.1194294⟩ Article dans une revue hal-03661172v1

	Reconstitution of Functionally Active Thermus thermophilus 30S Ribosomal Subunit from Ribosomal 16S RNA and Ribosomal Proteins Sultan Agalarov , Marat Yusupov , Gulnara Yusupova Nucleic Acid Crystallography, 1320, Springer New York, pp.303-314, 2016, Methods in Molecular Biology, ⟨10.1007/978-1-4939-2763-0_19⟩ Chapitre d'ouvrage hal-03661148v1

Gulnara Yusupova

Publications

Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents

mRNA reading frame maintenance during eukaryotic ribosome translocation

E-site drug specificity of the human pathogen Candida albicans ribosome

A Path to the Atomic-Resolution Structures of Prokaryotic and Eukaryotic Ribosomes

Accuracy mechanism of eukaryotic ribosome translocation

Inhibition of the Eukaryotic 80S Ribosome as a Potential Anticancer Therapy: A Structural Perspective

Mechanism of ribosome shutdown by RsfS in Staphylococcus aureus revealed by integrative structural biology approach

Cryo‐EM structure of the ribosome functional complex of the human pathogen Staphylococcus aureus at 3.2 Å resolution

Posttranslational modification of Elongation Factor P from Staphylococcus aureus

The multiple flavors of GoU pairs in RNA

Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome

Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome

Importance of potassium ions for ribosome structure and function revealed by long-wavelength X-ray diffraction

The Amaryllidaceae Alkaloid Haemanthamine Binds the Eukaryotic Ribosome to Repress Cancer Cell Growth

Tautomeric G•U pairs within the molecular ribosomal grip and fidelity of decoding in bacteria

Structure of the 70S ribosome from human pathogen Staphylococcus aureus

Aminoglycoside interactions and impacts on the eukaryotic ribosome

Crystal structure of eukaryotic ribosome and its complexes with inhibitors

Inhibition of Eukaryotic Translation by the Antitumor Natural Product Agelastatin A

Structures and dynamics of hibernating ribosomes from Staphylococcus aureus mediated by intermolecular interactions of HPF

Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides

Amicoumacin A induces cancer cell death by targeting the eukaryotic ribosome

Crystal Structure of Hypusine-Containing Translation Factor eIF5A Bound to a Rotated Eukaryotic Ribosome

Eukaryotic Ribosome as a Target for Cardiovascular Disease

Molecular insights into protein synthesis with proline residues

Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code

Crystal Structures of the uL3 Mutant Ribosome: Illustration of the Importance of Ribosomal Proteins for Translation Efficiency

New Structural Insights into Translational Miscoding

The ribosome prohibits the G•U wobble geometry at the first position of the codon–anticodon helix

Insights into the origin of the nuclear localization signals in conserved ribosomal proteins

Ribosome biochemistry in crystal structure determination

Structural insights into the translational infidelity mechanism

Recognition of Watson-Crick base pairs: constraints and limits due to geometric selection and tautomerism

Structural basis for the inhibition of the eukaryotic ribosome

High-Resolution Structure of the Eukaryotic 80S Ribosome

Structural basis for potent inhibitory activity of the antibiotic tigecycline during protein synthesis

New structural insights into the decoding mechanism: Translation infidelity via a G·U pair with Watson-Crick geometry

One core, two shells: bacterial and eukaryotic ribosomes

A new understanding of the decoding principle on the ribosome

Crystal structure of the 80S yeast ribosome

The Structure of the Eukaryotic Ribosome at 3.0 Å Resolution

Interactions of the ribosome with mRNA and tRNA

Structural aspects of messenger RNA reading frame maintenance by the ribosome

Structural rearrangements of the ribosome at the tRNA proofreading step

Crystal Structure of the Eukaryotic Ribosome

Reconstitution of Functionally Active Thermus thermophilus 30S Ribosomal Subunit from Ribosomal 16S RNA and Ribosomal Proteins