CV

Yury Zgadzay, Olga Kolosova, Artem Stetsenko, Cheng Wu, David Bruchlen, et al.. E-site drug specificity of the human pathogen Candida albicans ribosome. Science Advances , American Association for the Advancement of Science (AAAS), 2022, 8 (21), ⟨10.1126/sciadv.abn1062⟩. ⟨hal-03710959⟩

Simone Pellegrino, Salvatore Terrosu, Gulnara Yusupova, Marat Yusupov. Inhibition of the Eukaryotic 80S Ribosome as a Potential Anticancer Therapy: A Structural Perspective. Cancers, MDPI, 2021, 13 (17), pp.4392. ⟨10.3390/cancers13174392⟩. ⟨hal-03658602⟩

Gulnara Yusupova, Simone Pellegrino, Salvatore Terrosu, Marat Yusupov. Inhibition of the Eukaryotic 80S Ribosome as a Potential Anticancer Therapy: A Structural Perspective. Cancers, MDPI, 2021, 13 (17), pp.4392. ⟨10.3390/cancers13174392⟩. ⟨hal-03365738⟩

Simone Pellegrino, Salvatore Terrosu, Gulnara Yusupova, Marat Yusupov. Inhibition of the Eukaryotic 80S Ribosome as a Potential Anticancer Therapy: A Structural Perspective. Cancers, MDPI, 2021, 13 (17), pp.4392. ⟨10.3390/cancers13174392⟩. ⟨hal-03652911⟩

Muminjon Djumagulov, Natalia Demeshkina, Lasse Jenner, Alexey Rozov, Marat Yusupov, et al.. Accuracy mechanism of eukaryotic ribosome translocation. Nature, Nature Publishing Group, 2021, 600 (7889), pp.543-546. ⟨10.1038/s41586-021-04131-9⟩. ⟨hal-03652901⟩

Muminjon Djumagulov, Natalia Demeshkina, Lasse Jenner, Alexey Rozov, Marat Yusupov, et al.. Accuracy mechanism of eukaryotic ribosome translocation. Nature, Nature Publishing Group, 2021, 600 (7889), pp.543-546. ⟨10.1038/s41586-021-04131-9⟩. ⟨hal-03658596⟩

Gulnara Yusupova, Marat Yusupov. A Path to the Atomic-Resolution Structures of Prokaryotic and Eukaryotic Ribosomes. Биохимия / Biochemistry, MAIK Nauka/Interperiodica, 2021, 86 (8), pp.926-941. ⟨10.1134/S0006297921080046⟩. ⟨hal-03365744⟩

Gulnara Yusupova, Alexander Golubev, Luc Negroni, Filipp Krasnovid, Shamil Validov, et al.. Posttranslational modification of Elongation Factor P from Staphylococcus aureus. FEBS Open Bio, Wiley Open Access/Elsevier, 2020, 10 (7), pp.1342-1347. ⟨10.1002/2211-5463.12901⟩. ⟨hal-02997686⟩

Alexander Golubev, Bulat Fatkhullin, Iskander Khusainov, Lasse Jenner, Azat Gabdulkhakov, et al.. Cryo‐EM structure of the ribosome functional complex of the human pathogen Staphylococcus aureus at 3.2 Å resolution. FEBS Letters, Wiley, 2020, 594 (21), pp.3551 - 3567. ⟨10.1002/1873-3468.13915⟩. ⟨hal-03373743⟩

Gulnara Yusupova, Alexander Golubev, Bulat Fatkhullin, Iskander Khusainov, Lasse Jenner, et al.. Cryo‐EM structure of the ribosome functional complex of the human pathogen Staphylococcus aureus at 3.2 Å resolution. FEBS Letters, Wiley, 2020, ⟨10.1002/1873-3468.13915⟩. ⟨hal-02997677⟩

Simone Pellegrino, Mélanie Meyer, Zef Könst, Mikael Holm, Vamsee Voora, et al.. Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome. Nucleic Acids Research, Oxford University Press, 2019, 47 (6), pp.3223-3232. ⟨10.1093/nar/gkz053⟩. ⟨hal-03659840⟩

Alexey Rozov, Iskander Khusainov, Kamel El Omari, Ramona Duman, Vitaliy Mykhaylyk, et al.. Importance of potassium ions for ribosome structure and function revealed by long-wavelength X-ray diffraction. Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.2519. ⟨10.1038/s41467-019-10409-4⟩. ⟨hal-03659834⟩

Gulnara Yusupova, Simone Pellegrino, Mélanie Meyer, Zef Könst, Mikael Holm, et al.. Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome. Nucleic Acids Research, Oxford University Press, 2019, 47 (6), pp.3223-3232. ⟨10.1093/nar/gkz053⟩. ⟨hal-03365753⟩

Eric Westhof, Marat M. Yusupov, Gulnara Yusupova. The multiple flavors of GoU pairs in RNA. Journal of Molecular Recognition, Wiley, 2019, pp.e2782. ⟨10.1002/jmr.2782⟩. ⟨hal-02361230⟩

Simone Pellegrino, Mélanie Meyer, Christiane Zorbas, Soumaya Bouchta, Kritika Saraf, et al.. The Amaryllidaceae Alkaloid Haemanthamine Binds the Eukaryotic Ribosome to Repress Cancer Cell Growth. Structure, Elsevier (Cell Press), 2018, 26 (3), pp.416-425.e4. ⟨10.1016/j.str.2018.01.009⟩. ⟨hal-03661103⟩

Alexey Rozov, Philippe Wolff, Henri Grosjean, Marat Yusupov, Gulnara Yusupova, et al.. Tautomeric G•U pairs within the molecular ribosomal grip and fidelity of decoding in bacteria. Nucleic Acids Research, Oxford University Press, 2018, 46 (14), pp.7425-7435. ⟨10.1093/nar/gky547⟩. ⟨hal-03659841⟩

Gulnara Yusupova, Irina Prokhorova, Roger Altman, Muminjon Djumagulov, Jaya Shrestha, et al.. Aminoglycoside interactions and impacts on the eukaryotic ribosome. Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2017, 114 (51), pp.E10899-E10908. ⟨10.1073/pnas.1715501114⟩. ⟨hal-03365761⟩

Iskander Khusainov, Quentin Vicens, Anthony Bochler, François Grosse, Alexander G. Myasnikov, et al.. Structure of the 70S ribosome from human pathogen Staphylococcus aureus. Nucleic Acids Research, Oxford University Press, 2017, 45 (2), pp.1026-1026. ⟨10.1093/nar/gkw1126⟩. ⟨hal-02171293⟩

Zef Könst, Anne Szklarski, Simone Pellegrino, Sharon Michalak, Mélanie Meyer, et al.. Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides. Nature Chemistry, Nature Publishing Group, 2017, 9 (11), pp.1140-1149. ⟨10.1038/nchem.2800⟩. ⟨hal-03659848⟩

Iskander Khusainov, Quentin Vicens, Rustam Ayupov, Konstantin Usachev, Alexander Myasnikov, et al.. Structures and dynamics of hibernating ribosomes from Staphylococcus aureus mediated by intermolecular interactions of HPF. EMBO Journal, EMBO Press, 2017, 36 (14), pp.2073-2087. ⟨10.15252/embj.201696105⟩. ⟨hal-03661109⟩

Gulnara Yusupova, Marat Yusupov. Crystal structure of eukaryotic ribosome and its complexes with inhibitors. Philosophical Transactions of the Royal Society B: Biological Sciences, Royal Society, The, 2017, 372 (1716), pp.20160184. ⟨10.1098/rstb.2016.0184⟩. ⟨hal-03661123⟩

Brandon Mcclary, Boris Zinshteyn, Mélanie Meyer, Morgan Jouanneau, Simone Pellegrino, et al.. Inhibition of Eukaryotic Translation by the Antitumor Natural Product Agelastatin A. Cell Chemical Biology, Cell Press, 2017, 24 (5), pp.605-613.e5. ⟨10.1016/j.chembiol.2017.04.006⟩. ⟨hal-03661121⟩

Irina Prokhorova, Kseniya Akulich, Desislava Makeeva, Ilya Osterman, Dmitry Skvortsov, et al.. Amicoumacin A induces cancer cell death by targeting the eukaryotic ribosome. Scientific Reports, Nature Publishing Group, 2016, 6 (1), pp.27720. ⟨10.1038/srep27720⟩. ⟨hal-03661134⟩

Sergey Melnikov, Justine Mailliot, Byung-Sik Shin, Lukas Rigger, Gulnara Yusupova, et al.. Crystal Structure of Hypusine-Containing Translation Factor eIF5A Bound to a Rotated Eukaryotic Ribosome. Journal of Molecular Biology, Elsevier, 2016, 428 (18), pp.3570-3576. ⟨10.1016/j.jmb.2016.05.011⟩. ⟨hal-03661136⟩

Simone P Pellegrino, Gulnara Yusupova. Eukaryotic Ribosome as a Target for Cardiovascular Disease. Cell Chemical Biology, Cell Press, 2016, 17 (23), pp.1319-1321. ⟨10.1016/j.chembiol.2016.11.004⟩. ⟨inserm-01415698⟩

Justine Mailliot, Nicolas Garreau de Loubresse, Gulnara Yusupova, Arturas Meskauskas, Jonathan Dinman, et al.. Crystal Structures of the uL3 Mutant Ribosome: Illustration of the Importance of Ribosomal Proteins for Translation Efficiency. Journal of Molecular Biology, Elsevier, 2016, 428 (10), pp.2195-2202. ⟨10.1016/j.jmb.2016.02.013⟩. ⟨hal-03661143⟩

Alexey Rozov, Eric Westhof, Marat M. Yusupov, Gulnara Yusupova. The ribosome prohibits the G•U wobble geometry at the first position of the codon–anticodon helix. Nucleic Acids Research, Oxford University Press, 2016, 44 (13), pp.6434-41. ⟨10.1093/nar/gkw431⟩. ⟨hal-02294675⟩

Alexey Rozov, Natalia Demeshkina, Eric Westhof, Marat M. Yusupov, Gulnara Yusupova. New Structural Insights into Translational Miscoding. Trends in Biochemical Sciences, Elsevier, 2016, 41 (9), pp.798-814. ⟨10.1016/j.tibs.2016.06.001⟩. ⟨hal-02294531⟩

Sergey Melnikov, Justine Mailliot, Lukas Rigger, Sandro Neuner, Byung‐sik Shin, et al.. Molecular insights into protein synthesis with proline residues. EMBO Reports, EMBO Press, 2016, 17 (12), pp.1776-1784. ⟨10.15252/embr.201642943⟩. ⟨hal-03661132⟩

Alexey Rozov, Natalia Demeshkina, Iskander Khusainov, Eric Westhof, Marat M. Yusupov, et al.. Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code. Nature Communications, Nature Publishing Group, 2016, 7 (1), pp.10457. ⟨10.1038/ncomms10457⟩. ⟨hal-02294521⟩

Gulnara Yusupova, Marat Yusupov. Ribosome biochemistry in crystal structure determination. RNA, Cold Spring Harbor Laboratory Press, 2015, 21 (4), pp.771-773. ⟨10.1261/rna.050039.115⟩. ⟨hal-03661153⟩

Alexey Rozov, Natalia Demeshkina, Eric Westhof, Marat Yusupov, Gulnara Yusupova. Structural insights into the translational infidelity mechanism. Nature Communications, Nature Publishing Group, 2015, 6 (1), pp.7251. ⟨10.1038/ncomms8251⟩. ⟨hal-03661150⟩

Sergey Melnikov, Adam Ben-Shem, Gulnara Yusupova, Marat Yusupov. Insights into the origin of the nuclear localization signals in conserved ribosomal proteins. Nature Communications, Nature Publishing Group, 2015, 6 (1), pp.7382. ⟨10.1038/ncomms8382⟩. ⟨hal-03661149⟩

Eric Westhof, Marat Yusupov, Gulnara Yusupova. Recognition of Watson-Crick base pairs: constraints and limits due to geometric selection and tautomerism. F1000Prime Reports, 2014, 6, ⟨10.12703/P6-19⟩. ⟨hal-03661156⟩

Gulnara Yusupova, Marat Yusupov. High-Resolution Structure of the Eukaryotic 80S Ribosome. Annual Review of Biochemistry, Annual Reviews, 2014, 83 (1), pp.467-486. ⟨10.1146/annurev-biochem-060713-035445⟩. ⟨hal-03661159⟩

Nicolas Garreau de Loubresse, Irina Prokhorova, Wolf Holtkamp, Marina Rodnina, Gulnara Yusupova, et al.. Structural basis for the inhibition of the eukaryotic ribosome. Nature, Nature Publishing Group, 2014, 513 (7519), pp.517-522. ⟨10.1038/nature13737⟩. ⟨hal-03661154⟩

Natalia Demeshkina, Lasse Jenner, Eric Westhof, Marat Yusupov, Gulnara Yusupova. New structural insights into the decoding mechanism: Translation infidelity via a G·U pair with Watson-Crick geometry. FEBS Letters, Wiley, 2013, 587 (13), pp.1848-1857. ⟨10.1016/j.febslet.2013.05.009⟩. ⟨hal-03661161⟩

Lasse Jenner, Agata Starosta, Daniel Terry, Aleksandra Mikolajka, Liudmila Filonava, et al.. Structural basis for potent inhibitory activity of the antibiotic tigecycline during protein synthesis. Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2013, 110 (10), pp.3812-3816. ⟨10.1073/pnas.1216691110⟩. ⟨hal-03661163⟩

Lasse Jenner, Sergey Melnikov, Nicolas Garreau de Loubresse, Adam Ben-Shem, Madina Iskakova, et al.. Crystal structure of the 80S yeast ribosome. Current Opinion in Structural Biology, Elsevier, 2012, 22 (6), pp.759-767. ⟨10.1016/j.sbi.2012.07.013⟩. ⟨hal-03661164⟩

Sergey Melnikov, Adam Ben-Shem, Nicolas Garreau de Loubresse, Lasse Jenner, Gulnara Yusupova, et al.. One core, two shells: bacterial and eukaryotic ribosomes. Nature Structural and Molecular Biology, Nature Publishing Group, 2012, 19 (6), pp.560-567. ⟨10.1038/nsmb.2313⟩. ⟨hal-03661166⟩

Natalia Demeshkina, Lasse Jenner, Eric Westhof, Marat Yusupov, Gulnara Yusupova. A new understanding of the decoding principle on the ribosome. Nature, Nature Publishing Group, 2012, 484 (7393), pp.256-259. ⟨10.1038/nature10913⟩. ⟨hal-03661168⟩

Adam Ben-Shem, Nicolas Garreau de Loubresse, Sergey Melnikov, Lasse Jenner, Gulnara Yusupova, et al.. The Structure of the Eukaryotic Ribosome at 3.0 Å Resolution. Science, American Association for the Advancement of Science (AAAS), 2011, 334 (6062), pp.1524-1529. ⟨10.1126/science.1212642⟩. ⟨hal-03661170⟩

Natalia Demeshkina, Lasse Jenner, Gulnara Yusupova, Marat Yusupov. Interactions of the ribosome with mRNA and tRNA. Current Opinion in Structural Biology, Elsevier, 2010, 20 (3), pp.325-332. ⟨10.1016/j.sbi.2010.03.002⟩. ⟨hal-03661179⟩

Adam Ben-Shem, Lasse Jenner, Gulnara Yusupova, Marat Yusupov. Crystal Structure of the Eukaryotic Ribosome. Science, American Association for the Advancement of Science (AAAS), 2010, 330 (6008), pp.1203-1209. ⟨10.1126/science.1194294⟩. ⟨hal-03661172⟩

Lasse Jenner, Natalia Demeshkina, Gulnara Yusupova, Marat Yusupov. Structural aspects of messenger RNA reading frame maintenance by the ribosome. Nature Structural and Molecular Biology, Nature Publishing Group, 2010, 17 (5), pp.555-560. ⟨10.1038/nsmb.1790⟩. ⟨hal-03661176⟩

Lasse Jenner, Natalia Demeshkina, Gulnara Yusupova, Marat Yusupov. Structural rearrangements of the ribosome at the tRNA proofreading step. Nature Structural and Molecular Biology, Nature Publishing Group, 2010, 17 (9), pp.1072-1078. ⟨10.1038/nsmb.1880⟩. ⟨hal-03661174⟩

Sultan Agalarov, Marat Yusupov, Gulnara Yusupova. Reconstitution of Functionally Active Thermus thermophilus 30S Ribosomal Subunit from Ribosomal 16S RNA and Ribosomal Proteins. Nucleic Acid Crystallography, 1320, Springer New York, pp.303-314, 2016, Methods in Molecular Biology, ⟨10.1007/978-1-4939-2763-0_19⟩. ⟨hal-03661148⟩