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Guilherme Dias de Melo

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Neutralization, effector function and immune imprinting of Omicron variants

Amin Addetia , Luca Piccoli , James Brett Case , Young-Jun Park , Martina Beltramello
Nature, 2023, 621 (7979), pp.592-601. ⟨10.1038/s41586-023-06487-6⟩
Article dans une revue hal-04240898v1
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Lymphocytic hypophysitis in dogs infected with Leishmania spp.

Edenilson Doná Frigerio , Cecilia de Castro Guizelini , Giulia Gonçalves Jussiani , Karen Santos Março , Guilherme Dias de Melo
Frontiers in Veterinary Science, 2023, 10, pp.1208919. ⟨10.3389/fvets.2023.1208919⟩
Article dans une revue hal-04240909v1
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Neuroimmunology of rabies: New insights into an ancient disease

Victor Bastos , Vinicius Pacheco , Érika Rodrigues , Cássia Moraes , Adriel Nóbile
Journal of Medical Virology, 2023, 95 (10), pp.e29042. ⟨10.1002/jmv.29042⟩
Article dans une revue hal-04402518v1
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Increased CCL-5 (RANTES) Gene Expression in the Choroid Plexus of Dogs with Canine Leishmaniosis

José Eduardo dos Santos Silva , Giulia Gonçalves Jussiani , Fernanda Grecco Grano , Maria Cecília Clarindo Pelissari , Guilherme Dias de Melo
Animals, 2023, 13 (13), pp.2060. ⟨10.3390/ani13132060⟩
Article dans une revue hal-04240913v1
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Antiviral mechanisms of two broad-spectrum monoclonal antibodies for rabies prophylaxis and therapy

Maira Zorzan , Martina Castellan , Matteo Gasparotto , Guilherme Dias de Melo , Barbara Zecchin
Frontiers in Immunology, 2023, 14, pp.1186063. ⟨10.3389/fimmu.2023.1186063⟩
Article dans une revue hal-04240904v1
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Neuroinvasion and anosmia are independent phenomena upon infection with SARS-CoV-2 and its variants

Guilherme Dias de Melo , Victoire Perraud , Flavio Alvarez , Alba Vieites-Prado , Seonhee Kim
Nature Communications, 2023, 14 (1), pp.4485. ⟨10.1038/s41467-023-40228-7⟩
Article dans une revue pasteur-04171251v1
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Development of a highly specific and sensitive VHH-based sandwich immunoassay for the detection of the SARS-CoV-2 nucleoprotein

Marion Gransagne , Gabriel Aymé , Sébastien Brier , Gaëlle Chauveau-Le Friec , Véronique Meriaux
Journal of Biological Chemistry, 2022, 298 (1), pp.101290. ⟨10.1016/j.jbc.2021.101290⟩
Article dans une revue pasteur-03524979v1
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Monoclonal antibodies against rabies: current uses in prophylaxis and in therapy

Guilherme Dias de Melo , Jan Hellert , Rajesh Gupta , Davide Corti , Hervé Bourhy
Current Opinion in Virology, 2022, 53, pp.101204. ⟨10.1016/j.coviro.2022.101204⟩
Article dans une revue pasteur-03827722v1
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Potent human broadly SARS-CoV-2–neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2

Cyril Planchais , Ignacio Fernández , Timothée Bruel , Guilherme Dias de Melo , Matthieu Prot
Journal of Experimental Medicine, 2022, 219 (7), pp.e20220638. ⟨10.1084/jem.20220638⟩
Article dans une revue hal-03697587v1
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Irreversible inhibitors of the proline racemase (PRAC) unveil innovative mechanism of action as antibacterial against Clostridioides difficile

Cécile Gateau , Guilherme Dias de Melo , Philippe Uriac , Olivier Tasseau , Jacques Renault
Chemical Biology and Drug Design, 2022, 99 (4), pp.513-526. ⟨10.1111/cbdd.14005⟩
Article dans une revue hal-03504249v1
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Imprinted antibody responses against SARS-CoV-2 Omicron sublineages

Young-Jun Park , Dora Pinto , Alexandra C. Walls , Zhuoming Liu , Anna de Marco
Science, 2022, pp.First release. ⟨10.1126/science.adc9127⟩
Article dans une revue pasteur-03827707v1
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Bone marrow fat, visceral fat, and body conditions as parameters of possible neglect in dogs with leishmaniasis

Hugo Ribeiro Morais , Karen Santos Março , Lívia Castanhas Bregano , Thiago Luís Magnani Grassi , Tulio Faria Seraguci
Forensic Science International: Animals and Environments, 2022, 2, pp.100049. ⟨10.1016/j.fsiae.2022.100049⟩
Article dans une revue pasteur-03827728v1
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Prodrugs as new therapies against Chagas disease: In vivo synergy between Trypanosoma cruzi proline racemase inhibitors and benznidazole

Guilherme Dias de Melo , Nicolas Coatnoan , Nicolas Gouault , Jean-François Cupif , Jacques Renault
Journal of Global Antimicrobial Resistance, 2022, 28, pp.84-89. ⟨10.1016/j.jgar.2021.10.030⟩
Article dans une revue hal-03504248v1
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Susceptibilities of CNS Cells towards Rabies Virus Infection Is Linked to Cellular Innate Immune Responses

Lena Feige , Tatsuya Kozaki , Guilherme Dias de Melo , Vincent Guillemot , Florence Larrous
Viruses, 2022, 15 (1), pp.88. ⟨10.3390/v15010088⟩
Article dans une revue pasteur-03919985v1
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Structure of the rabies virus glycoprotein trimer bound to a prefusion-specific neutralizing antibody

Heather Callaway , Dawid Zyla , Florence Larrous , Guilherme Dias de Melo , Kathryn Hastie
Science Advances , 2022, 8 (24), ⟨10.1126/sciadv.abp9151⟩
Article dans une revue pasteur-03698942v1
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Attenuation of clinical and immunological outcomes during SARS‐CoV‐2 infection by ivermectin

Guilherme Dias de Melo , Françoise Lazarini , Florence Larrous , Lena Feige , Etienne Kornobis
EMBO Molecular Medicine, 2021, 13 (8), pp.e14122. ⟨10.15252/emmm.202114122⟩
Article dans une revue pasteur-03279176v1
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A live measles-vectored COVID-19 vaccine induces strong immunity and protection from SARS-CoV-2 challenge in mice and hamsters

Phanramphoei N. Frantz , Aleksandr Barinov , Claude Ruffié , Chantal Combredet , Valérie Najburg
Nature Communications, 2021, 12 (1), pp.6277. ⟨10.1038/s41467-021-26506-2⟩
Article dans une revue pasteur-03416317v1
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COVID-19-related anosmia is associated with viral persistence and inflammation in human olfactory epithelium and brain infection in hamsters

Guilherme Dias de Melo , Françoise Lazarini , Sylvain Levallois , Charlotte Hautefort , Vincent Michel
Science Translational Medicine, 2021, pp.eabf8396. ⟨10.1126/scitranslmed.abf8396⟩
Article dans une revue pasteur-03242618v1

Intrathecal Transplantation of Autologous and Allogeneic Bone Marrow-Derived Mesenchymal Stem Cells in Dogs

Felipe Pérez Benavides , Giovana Boff Araujo Pinto , Marta Cristina Thomas Heckler , Diana Milena Rodríguez Hurtado , Livia Ramos Teixeira
Cell Transplantation, 2021, 30, pp.096368972110344. ⟨10.1177/09636897211034464⟩
Article dans une revue hal-03504205v1
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SARS-CoV-2 infection induces the dedifferentiation of multiciliated cells and impairs mucociliary clearance

Rémy Robinot , Mathieu Hubert , Guilherme Dias de Melo , Françoise Lazarini , Timothée Bruel
Nature Communications, 2021, 12 (1), pp.4354. ⟨10.1038/s41467-021-24521-x⟩
Article dans une revue pasteur-03319522v1

Two-photon microscopy analysis reveals different pulmonary damage after infection by influenza or SARS-CoV-2

Frédéric Rivière , François Lefèvre , Julien Burger , Guilherme Dias de Melo , Jean Nicolas Tournier
Respiratory Medicine and Research, 2021, 80, pp.100862. ⟨10.1016/j.resmer.2021.100862⟩
Article dans une revue hal-03504202v1
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Nouveaux aspects de la lutte contre la rage

Hervé Bourhy , Guilherme Dias de Melo , Arnaud Tarantola
Bulletin de l'Académie Nationale de Médecine, 2020, ⟨10.1016/j.banm.2020.09.036⟩
Article dans une revue pasteur-02983037v1
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Structure of the prefusion-locking broadly neutralizing antibody RVC20 bound to the rabies virus glycoprotein

Jan Hellert , Julian Buchrieser , Florence Larrous , Andrea Minola , Guilherme Dias de Melo
Nature Communications, 2020, 11 (1), pp.596. ⟨10.1038/s41467-020-14398-7⟩
Article dans une revue pasteur-02868882v1
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A combination of two human monoclonal antibodies cures symptomatic rabies

Guilherme Dias de Melo , Florian Sonthonnax , Gabriel Lepousez , Grégory Jouvion , Andrea Minola
EMBO Molecular Medicine, 2020, pp.e12628. ⟨10.15252/emmm.202012628⟩
Article dans une revue pasteur-02983042v1

Leishmania hide-and-seek: Parasite amastigotes in the choroid plexus of a dog with neurological signs in an endemic municipality in Brazil

Fernanda Grecco Grano , José Eduardo dos Santos Silva , Guilherme Dias De Melo , Gisele Fabrino Machado
Veterinary Parasitology : Regional Studies and Reports, 2019, 17, pp.100291. ⟨10.1016/j.vprsr.2019.100291⟩
Article dans une revue hal-03504206v1

Matrix metalloproteinases 2 and 9 in rabbits with doxorubicin-induced cardiomyopathy

Sheila S.S. Nogueira , Marlos Sousa , Fabio Gava , Fernando Rosa , Guilherme Melo
Pesquisa Veterinária Brasileira, 2018, 38 (2), pp.320-327. ⟨10.1590/1678-5150-PVB-4990⟩
Article dans une revue hal-03504209v1
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Designed mono- and di-covalent inhibitors trap modeled functional motions for Trypanosoma cruzi proline racemase in crystallography

Patricia de Aguiar Amaral , Delphine Autheman , Guilherme Dias de Melo , Nicolas Gouault , Jean-François Cupif
PLoS Neglected Tropical Diseases, 2018, 12 (10), ⟨10.1371/journal.pntd.0006853⟩
Article dans une revue hal-01935360v1

Toll-like receptors and cytokines in the brain and in spleen of dogs with visceral leishmaniosis

Fernanda Grano , José Eduardo dos S. Silva , Guilherme Melo , Milena de Souza , Valéria M.F. Lima
Veterinary Parasitology, 2018, 253, pp.30-38. ⟨10.1016/j.vetpar.2018.02.030⟩
Article dans une revue hal-03504207v1

Expression of matrix metalloproteinase-2 and metalloproteinase-9 in the skin of dogs with visceral leishmaniasis

Ana Paula Prudente Jacintho , Guilherme Melo , Gisele Machado , Paulo Henrique Leal Bertolo , Pamela Rodrigues Reina Moreira
Parasitology Research, 2018, 117 (6), pp.1819-1827. ⟨10.1007/s00436-018-5868-9⟩
Article dans une revue hal-03504208v1

Metaloproteinases no tecido laminar do casco de equinos submetidos à obstrução intraluminal do cólon menor

V.A. Canello , K. Gravena , M.C.H. Tovar , D.P.M. Dias , L.M.W. Gomide
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2018, 70 (1), pp.45-52. ⟨10.1590/1678-4162-9378⟩
Article dans une revue hal-03504211v1
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Detection of natural occurrence of Tritrichomonas foetus in cats in Araçatuba, São Paulo, Brazil

Roberta Duarte , Paulo Ricardo D.A. Rocha , Alex Nakamura , Rafael Cipriano , Milena Viol
Pesquisa Veterinária Brasileira, 2018, 38 (2), pp.309-314. ⟨10.1590/1678-5150-PVB-5115⟩
Article dans une revue hal-03504210v1
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New insights into experimental visceral leishmaniasis: Real-time in vivo imaging of Leishmania donovani virulence

Guilherme Dias de Melo , Sophie Goyard , Hervé Lecoeur , Eline Rouault , Pascale Pescher
PLoS Neglected Tropical Diseases, 2017, 11 (9), pp.e0005924. ⟨10.1371/journal.pntd.0005924⟩
Article dans une revue hal-03504212v1

Perceptions of animal experimentation: a longitudinal survey with veterinary students in Araçatuba, São Paulo, Brazil

Gisele Machado , Guilherme Dias de Melo , Silvia Perri , Fernando Fernandes , Olívia Moraes
Journal of Biological Education, 2017, 51 (4), pp.391-398. ⟨10.1080/00219266.2016.1257501⟩
Article dans une revue hal-03504213v1
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Unveiling Cerebral Leishmaniasis: parasites and brain inflammation in Leishmania donovani infected mice

Guilherme D. Melo , Sophie Goyard , Laurence Fiette , Alexandre Boissonnas , Christophe Combadiere
Scientific Reports, 2017, 7, pp.8454. ⟨10.1038/s41598-017-09085-5⟩
Article dans une revue hal-01581802v1

Blood pressure and renal injury in dogs with visceral leishmaniasis

Marlos Sousa , Amanda B.G. Lima , Cristiane R.A. Araújo , Vinícius B.C. Silva , Adriano Ramos
Pesquisa Veterinária Brasileira, 2016, 36 (9), pp.857-863. ⟨10.1590/S0100-736X2016000900011⟩
Article dans une revue hal-03504216v1

Identification of Leishmania spp. promastigotes in the intestines, ovaries, and salivary glands of Rhipicephalus sanguineus actively infesting dogs

Milena Araúz Viol , Felix Guerrero , Bruno César Miranda de Oliveira , Monally Conceição Costa de Aquino , Saulo Hudson Loiola
Parasitology Research, 2016, 115 (9), pp.3479-3484. ⟨10.1007/s00436-016-5111-5⟩
Article dans une revue hal-03504214v1

T lymphocyte immunophenotypes in the cerebrospinal fluid of dogs with visceral leishmaniasis

Fernanda Grano , José Eduardo dos S. Silva , Guilherme Dias de Melo , Juliana Perosso , Valéria M.F. Lima
Veterinary Parasitology, 2016, 232, pp.12-20. ⟨10.1016/j.vetpar.2016.11.006⟩
Article dans une revue hal-03504215v1

Serological, parasitological and molecular tests for canine visceral leishmaniosis diagnosis in a longitudinal study

Cáris Maroni Nunes , Valéria Marçal Félix De Lima , Guilherme Dias De Melo , Henrique Borges De Paula , Maria Esther Gonçalves Pereira
Revista Brasileira de Parasitologia Veterinária, 2015, 24 (4), pp.402-409. ⟨10.1590/S1984-29612015073⟩
Article dans une revue hal-03504221v1

Feasibility and safety of intrathecal transplantation of autologous bone marrow mesenchymal stem cells in horses

Leandro Maia , Fernanda da Cruz Landim- Alvarenga , Marilda Onghero Taffarel , Carolina Nogueira de Moraes , Gisele Fabrino Machado
BMC Veterinary Research, 2015, 11 (1), ⟨10.1186/s12917-015-0361-5⟩
Article dans une revue hal-03504220v1

Blood-brain barrier disruption during spontaneous canine visceral leishmaniasis

G.D. de Melo , F. Grano , J. Silva , B. Kremer , V. Lima
Parasite Immunology, 2015, 37 (12), pp.635-645. ⟨10.1111/pim.12285⟩
Article dans une revue hal-03504217v1

Leishmania infection and neuroinflammation: Specific chemokine profile and absence of parasites in the brain of naturally-infected dogs

Guilherme Dias de Melo , José Eduardo S. Silva , Fernanda Grano , Milena Souza , Gisele Machado
Journal of Neuroimmunology, 2015, 289, pp.21-29. ⟨10.1016/j.jneuroim.2015.10.004⟩
Article dans une revue hal-03504218v1

First detection of Leishmania infantum DNA within the brain of naturally infected dogs

Fernanda Grano , Guilherme Melo , Silvia Belinchón-Lorenzo , Luis Gómez-Nieto , Gisele Machado
Veterinary Parasitology, 2014, 204 (3-4), pp.376-380. ⟨10.1016/j.vetpar.2014.05.015⟩
Article dans une revue hal-03504223v1

Compartmentalized gene expression of toll-like receptors 2, 4 and 9 in the brain and peripheral lymphoid organs during canine visceral leishmaniasis

Guilherme Dias de Melo , J. Silva , F. Grano , C. Homem , G. Machado
Parasite Immunology, 2014, 36 (12), pp.726-731. ⟨10.1111/pim.12148⟩
Article dans une revue hal-03504224v1

Zymographic patterns of MMP-2 and MMP-9 in the CSF and cerebellum of dogs with subacute distemper leukoencephalitis

Gisele Machado , Guilherme Dias de Melo , Milena Souza , Andressa Machado , Daniela Migliolo
Veterinary Immunology and Immunopathology, 2013, 154 (1-2), pp.68-74. ⟨10.1016/j.vetimm.2013.04.006⟩
Article dans une revue hal-03504228v1

Bovine herpesvirus-5 infection in a rabbit experimental model: Immunohistochemical study of the cellular response in the CNS

Gisele Machado , Fernanda Bernardi , Fernando Y.M. Hosomi , Juliana Peiró , Rudi Weiblen
Microbial Pathogenesis, 2013, 57, pp.10-16. ⟨10.1016/j.micpath.2013.01.003⟩
Article dans une revue hal-03504227v1

Pro-inflammatory cytokines predominate in the brains of dogs with visceral leishmaniasis: A natural model of neuroinflammation during systemic parasitic infection

Guilherme Melo , Túlio Seraguci , Augusto Schweigert , José Eduardo S. Silva , Fernanda Grano
Veterinary Parasitology, 2013, 192 (1-3), pp.57-66. ⟨10.1016/j.vetpar.2012.11.002⟩
Article dans une revue hal-03504229v1

Ki-67 labeling in canine perianal glands neoplasms: a novel approach for immunohistological diagnostic and prognostic

Rodrigo Storti Pereira , Augusto Schweigert , Guilherme Dias De Melo , Fernando Vissani Fernandes , Felipe Augusto Ruiz Sueiro
BMC Veterinary Research, 2013, 9 (1), ⟨10.1186/1746-6148-9-83⟩
Article dans une revue hal-03504230v1

T and B lymphocytes in the brains of dogs with concomitant seropositivity to three pathogenic protozoans: Leishmania chagasi, Toxoplasma gondii and Neospora caninum

Keila Priscilla Sakamoto , Guilherme Dias de Melo , Gisele Fabrino Machado
BMC Research Notes, 2013, 6 (1), ⟨10.1186/1756-0500-6-226⟩
Article dans une revue hal-03504233v1

Canine cerebral leishmaniasis: Potential role of matrix metalloproteinase-2 in the development of neurological disease

Guilherme Dias de Melo , Mary Marcondes , Gisele Machado
Veterinary Immunology and Immunopathology, 2012, 148 (3-4), pp.260-266. ⟨10.1016/j.vetimm.2012.05.007⟩
Article dans une revue hal-03504235v1

Visceral mast cell tumor and mastocythemia in a dog

Fernanda Grecco Grano , José Eduardo dos Santos Silva , G.D. Melo , Augusto Schweigert , P.C. Ciarlini
Brazilian Journal of Veterinary Pathology, 2012, 5 (3), pp.142-145
Article dans une revue hal-03504245v1

Porencephaly and cortical dysplasia as cause of seizures in a dog

Gisele Fabrino Machado , Maria-Gisela Laranjeira , Augusto Schweigert , Guilherme Dias de Melo
BMC Veterinary Research, 2012, 8 (1), pp.246. ⟨10.1186/1746-6148-8-246⟩
Article dans une revue hal-03504236v1

Squamous Cell Lung Carcinoma in a Cat

José Eduardo dos Santos Silva , Fernanda Grecco Grano , G.D. Melo , Augusto Schweigert , L.D.R.P. Ciarlini
Brazilian Journal of Veterinary Pathology, 2012, 5 (3), pp.133-136
Article dans une revue hal-03504246v1

High levels of serum matrix metalloproteinases in dogs with natural visceral leishmaniosis: A preliminary report

Guilherme Melo , Natalia Marangoni , Mary Marcondes , Valéria M.F. Lima , Gisele Machado
Veterinary Journal, 2011, 188 (2), pp.243-245. ⟨10.1016/j.tvjl.2010.03.017⟩
Article dans une revue hal-03504240v1

Glial reactivity in dogs with visceral leishmaniasis: correlation with T lymphocyte infiltration and with cerebrospinal fluid anti-Leishmania antibody titres

Guilherme Dias de Melo , Gisele Machado
Cell and Tissue Research, 2011, 346 (3), pp.293-304. ⟨10.1007/s00441-011-1290-7⟩
Article dans une revue hal-03504239v1

Levels of matrix metalloproteinase-2 and metalloproteinase-9 in the cerebrospinal fluid of dogs with visceral leishmaniasis

N. Marangoni , G.D. Melo , O. Moraes , M. Souza , S. Perri
Parasite Immunology, 2011, 33 (6), pp.330-334. ⟨10.1111/j.1365-3024.2011.01285.x⟩
Article dans une revue hal-03504238v1

Intravascular lymphomatosis in the central nervous system of dogs: immunohistochemical investigation in two cases

G.F. Machado , M.B. Castro , G.D. Melo , W.L. Ferreira , E.G. Aylon
Brazilian Journal of Veterinary Pathology, 2011, 4 (1), pp.47-51
Article dans une revue hal-03504243v1

Differential alterations in the activity of matrix metalloproteinases within the nervous tissue of dogs in distinct manifestations of visceral leishmaniasis

Gisele Machado , Guilherme Melo , Olívia Moraes , Milena Souza , Mary Marcondes
Veterinary Immunology and Immunopathology, 2010, 136 (3-4), pp.340-345. ⟨10.1016/j.vetimm.2010.03.024⟩
Article dans une revue hal-03504198v1

Choroid plexus involvement in dogs with spontaneous visceral leishmaniasis: a histopathological investigation

G.D. Melo , G.F. Machado
Brazilian Journal of Veterinary Pathology, 2009, 2 (2), pp.69-74
Article dans une revue hal-03504244v1

Leukocyte entry into the CNS of Leishmania chagasi naturally infected dogs

G.D. Melo , M. Marcondes , R.O. Vasconcelos , G.F. Machado
Veterinary Parasitology, 2009, 162 (3-4), pp.248-256. ⟨10.1016/j.vetpar.2009.03.002⟩
Article dans une revue hal-03503869v1

Infections of the Central Nervous System - Chapter 13: Rabies

Guilherme Dias de Melo , Perrine Parize , Grégory Jouvion , Laurent Dacheux , Fabrice Chrétien
Fabrice Chrétien. Infections of the Central Nervous System: Pathology and Genetics, Wiley, 2020, 978-1-119-46774-8 (ebook). ⟨10.1002/9781119467748.ch13⟩
Chapitre d'ouvrage hal-03506122v1