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“ One Ring to Bind Them All ”—Part II: Identification of Promising G-Quadruplex Ligands by Screening of Cyclophane-Type Macrocycles

 Anton Granzhan , David Monchaud , Nicolas Saettel , Aurore Guédin , Jean-Louis Mergny , et al.
Journal of Nucleic Acids , 2010, 2010, pp.460561. ⟨10.4061/2010/460561⟩
Article dans une revue hal-02310164v1
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Disclosing the actual efficiency of G-quadruplex DNA-disrupting small molecules

 Jeremie Mitteaux , Pauline Lejault , Marc Pirrotta , Filip Wojciechowski , Alexandra Joubert , et al.
2020
Pré-publication, Document de travail hal-03010325v1
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Assessment of presumed small-molecule ligands of telomeric i-DNA by biolayer interferometry (BLI)

 Hugues Bonnet , Maéva Morel , Alexandre Devaux , Joseph Boissieras , Anton Granzhan , et al.
Chemical Communications, 2022, 58 (33), pp.5116. ⟨10.1039/D2CC00836J⟩
Article dans une revue hal-03632613v2
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“ One Ring to Bind Them All ”—Part I: The Efficiency of the Macrocyclic Scaffold for G-Quadruplex DNA Recognition

 David Monchaud , Anton Granzhan , Nicolas Saettel , Aurore Guédin , Jean-Louis Mergny , et al.
Journal of Nucleic Acids , 2010, 2010, pp.1-19. ⟨10.4061/2010/525862⟩
Article dans une revue hal-02125700v1
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Topology-Selective Fluorescent "Light-Up" Probes for G-Quadruplex DNA Based on Photoinduced Electron Transfer

 Xiao Xie , Oksana Reznichenko , Ludovic Chaput , Pascal G.P. Martin , Marie-Paule Teulade-Fichou , et al.
Chemistry - A European Journal, 2018, ⟨10.1002/chem.201801701⟩
Article dans une revue hal-01821778v1
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Dye-functionalized phosphate-binding macrocycles: from nucleotide to G-quadruplex recognition and “turn-on” fluorescence sensing

 Aleksandr S Oshchepkov , Oksana Reznichenko , Dan Xu , Boris S Morozov , Anton Granzhan , et al.
Chemical Communications, 2021, 57 (81), pp.10632-10635. ⟨10.1039/D1CC04096K⟩
Article dans une revue hal-03404501v1
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Guidelines for G-quadruplexes: I. In vitro characterization

 Yu Luo , Anton Granzhan , Julien Marquevielle , Anne Cucchiarini , Laurent Lacroix , et al.
Biochimie, 2022, 214, pp.5-23. ⟨10.1016/j.biochi.2022.12.019⟩
Article dans une revue inserm-03979024v1
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Monitoring DNA–Ligand Interactions in Living Human Cells Using NMR Spectroscopy

 Michaela Krafcikova , Simon Dzatko , Coralie Caron , Anton Granzhan , Radovan Fiala , et al.
Journal of the American Chemical Society, 2019, 141 (34), pp.13281-13285. ⟨10.1021/jacs.9b03031⟩
Article dans une revue hal-02344480v1

Cationic azacryptands as selective three-way DNA junction binding agents

 Jana Novotna , Aurélien Laguerre , Anton Granzhan , Marc Pirrotta , Marie-Paule Teulade-Fichou , et al.
Organic & Biomolecular Chemistry, 2015, 13 (1), pp.215-222. ⟨10.1039/C4OB01846J⟩
Article dans une revue hal-02125771v1
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TWJ-Screen: an isothermal screening assay to assess ligand/DNA junction interactions in vitro

 Ludivine Guyon , Marc Pirrotta , Katerina Duskova , Anton Granzhan , Marie-Paule Teulade-Fichou , et al.
Nucleic Acids Research, 2018, 46 (3), pp.e16-e16. ⟨10.1093/nar/gkx1118⟩
Article dans une revue hal-02121526v2
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Identification of optimal fluorescent probes for G-quadruplex nucleic acids through systematic exploration of mono- and distyryl dye libraries

 Xiao Xie , Michela Zuffo , Marie-Paule Teulade-Fichou , Anton Granzhan
Beilstein Journal of Organic Chemistry, 2019, 15, pp.1872-1889. ⟨10.3762/bjoc.15.183⟩
Article dans une revue hal-02344509v1
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Harnessing an emissive guanine surrogate to design small-molecule fluorescent chemosensors of O6-methylguanine-DNA-methyltransferase (MGMT)

 Alexandra Fillion , Jaime Franco Pinto , Anton Granzhan
Organic & Biomolecular Chemistry, 2022, 20 (9), pp.1888-1892. ⟨10.1039/D2OB00208F⟩
Article dans une revue hal-03837846v1
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Identifying G-Quadruplex-DNA-Disrupting Small Molecules

 Jérémie Mitteaux , Pauline Lejault , Filip Wojciechowski , Alexandra Joubert , Julien Boudon , et al.
Journal of the American Chemical Society, 2021, 143 (32), pp.12567-12577. ⟨10.1021/jacs.1c04426⟩
Article dans une revue hal-03321473v1
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SARS-CoV-2 Nsp3 unique domain SUD interacts with guanine quadruplexes and G4-ligands inhibit this interaction

 Marc Lavigne , Olivier Helynck , Pascal Rigolet , Rofia Boudria-Souilah , Mireille Nowakowski , et al.
Nucleic Acids Research, 2021, 49 (13), pp.7695-7712. ⟨10.1093/nar/gkab571⟩
Article dans une revue hal-03281130v1
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A novel Hsp70 inhibitor prevents cell intoxication with the actin ADP-ribosylating Clostridium perfringens iota toxin

 Katharina Ernst , Markus Liebscher , Sebastian Mathea , Anton Granzhan , Johannes Schmid , et al.
Scientific Reports, 2016, 6 (1), pp.20301. ⟨10.1038/srep20301⟩
Article dans une revue pasteur-01783777v1
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Quadruplex-interacting compounds for regulating the translation of the Epstein–Barr virus nuclear antigen 1 (EBNA1) mRNA: A new strategy to prevent and treat EBV-related cancers

 Anton Granzhan , Rodrigo Prado Martins , Robin Fåhraeus , Marc Blondel , Marie‐paule Teulade‐fichou
Stephen Neidle. Quadruplex Nucleic Acids As Targets For Medicinal Chemistry, 54, Elsevier, pp.243 - 286, 2020, Annual Reports in Medicinal Chemistry, 978-0-12-821017-8. ⟨10.1016/bs.armc.2020.05.001⟩
Chapitre d'ouvrage hal-03025274v1
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Identification of Three-Way DNA Junction Ligands through Screening of Chemical Libraries and Validation by Complementary in Vitro Assays

 Katerina Duskova , Jérémy Lamarche , Souheila Amor , Coralie Caron , Nicolas Queyriaux , et al.
Journal of Medicinal Chemistry, 2019, 62 (9), pp.4456-4466. ⟨10.1021/acs.jmedchem.8b01978⟩
Article dans une revue hal-02121543v3
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Novel cationic bis(acylhydrazones) as modulators of Epstein–Barr virus immune evasion acting through disruption of interaction between nucleolin and G-quadruplexes of EBNA1 mRNA

 Oksana Reznichenko , Alicia Quillévéré , Rodrigo Prado Martins , Nadège Loaëc , Hang Kang , et al.
European Journal of Medicinal Chemistry, 2019, 178, pp.13-29. ⟨10.1016/j.ejmech.2019.05.042⟩
Article dans une revue hal-02344559v1
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The different activities of RNA G-quadruplex structures are controlled by flanking sequences

 Alice J-L Zheng , Aikaterini Thermou , Pedro Guixens Gallardo , Laurence Malbert-Colas , Chrysoula Daskalogianni , et al.
Life Science Alliance, 2022, 5 (2), 15 p. ⟨10.26508/lsa.202101232⟩
Article dans une revue hal-03463719v1
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Unprecedented reactivity of polyamines with aldehydic DNA modifications: structural determinants of reactivity, characterization and enzymatic stability of adducts

 Eka Putra Gusti Ngurah Putu , Laurent Cattiaux , Thomas Lavergne , Yves Pommier , Sophie Bombard , et al.
Nucleic Acids Research, 2023, ⟨10.1093/nar/gkad837⟩
Article dans une revue hal-04261821v1
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Novel Synthesis of IMC-48 and Affinity Evaluation with Different i-Motif DNA Sequences

 Florian Berthiol , Joseph Boissieras , Hugues Bonnet , Marie Pierrot , Christian Philouze , et al.
Molecules, 2023, 28 (2), pp.682. ⟨10.3390/molecules28020682⟩
Article dans une revue hal-03933153v2
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Interaction of Functionalized Naphthalenophanes with Abasic Sites in DNA: DNA Cleavage, DNA Cleavage Inhibition, and Formation of Ligand-DNA Adducts

 Coralie Caron , Xuan N T Duong , Régis Guillot , Sophie Bombard , Anton Granzhan
Chemistry - A European Journal, 2019, 25 (8), pp.1949-1962. ⟨10.1002/chem.201805555⟩
Article dans une revue hal-02344667v1

Recognition of G‐Quadruplex DNA by Triangular Star‐Shaped Compounds: With or Without Side Chains?

 Hélène Bertrand , Anton Granzhan , David Monchaud , Nicolas Saettel , Régis Guillot , et al.
Chemistry - A European Journal, 2011, 17 (16), pp.4529-4539. ⟨10.1002/chem.201002810⟩
Article dans une revue istex hal-02125704v1
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Dual targeting of higher-order DNA structures by azacryptands induces DNA junction-mediated DNA damage in cancer cells

 Joanna Zell , Katerina Duskova , Leïla Chouh , Madeleine Bossaert , Nicolas Chéron , et al.
Nucleic Acids Research, 2021, 49 (18), pp.10275 - 10288. ⟨10.1093/nar/gkab796⟩
Article dans une revue hal-03372655v1
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Ligand-Induced Conformational Changes with Cation Ejection upon Binding to Human Telomeric DNA G-Quadruplexes

 Adrien Marchand , Anton Granzhan , Keisuke Iida , Yamato Tsushima , Yue Ma , et al.
Journal of the American Chemical Society, 2015, 137 (2), pp.750-756. ⟨10.1021/ja5099403⟩
Article dans une revue hal-01524156v1
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Probing of G-Quadruplex Structures via Ligand-Sensitized Photochemical Reactions in BrU-Substituted DNA

 Abhijit Saha , Sophie Bombard , Anton Granzhan , Marie-Paule Teulade-Fichou
Scientific Reports, 2018, 8 (1), pp.15814. ⟨10.1038/s41598-018-34141-z⟩
Article dans une revue hal-04481666v1

Double threading through DNA: NMR structural study of a bis-naphthalene macrocycle bound to a thymine–thymine mismatch

 Muriel Jourdan , Anton Granzhan , Régis Guillot , Pascal Dumy , Marie-Paule Teulade-Fichou
Nucleic Acids Research, 2012, 40 (11), pp.5115 - 5128. ⟨10.1093/nar/gks067⟩
Article dans une revue hal-01654807v1
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Optimization of G‐Quadruplex Ligands through a SAR Study by Combining Parallel Synthesis and Screening of Cationic Bis(acylhydrazones)

 Oksana Reznichenko , Denis Leclercq , Jaime Franco Pinto , Liliane Mouawad , Valérie Gabelica , et al.
Chemistry - A European Journal, 2022, ⟨10.1002/chem.202202427⟩
Article dans une revue hal-03837862v1
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The hide-and-seek game of the oncogenic Epstein-Barr virus-encoded EBNA1 protein with the immune system: An RNA G-quadruplex tale

 Van-Trang Dinh , Nadège Loaëc , Alicia Quillévéré , Ronan Le Sénéchal , Marc Keruzoré , et al.
Biochimie, 2023, 214 (Pt A), pp.57-68. ⟨10.1016/j.biochi.2023.07.010⟩
Article dans une revue hal-04186108v1
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Quadruplex DNA-guided ligand selection from dynamic combinatorial libraries of acylhydrazones

 Oksana Reznichenko , Anne Cucchiarini , Valérie Gabelica , Anton Granzhan
Organic & Biomolecular Chemistry, 2021, 19 (2), pp.379-386. ⟨10.1039/D0OB01908A⟩
Article dans une revue hal-03186431v1
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