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Cathepsin V: Molecular characteristics and significance in health and disease

Fabien Lecaille , Thibault Chazeirat , Ahlame Saidi , Gilles Lalmanach
Molecular Aspects of Medicine, 2022, pp.101086. ⟨10.1016/j.mam.2022.101086⟩
Article dans une revue hal-03677295v1

Identification of two new proteases of the apicomplexan parasite Eimeria tenella as potential therapeutic targets of avian cocddiosis

Fabien Brossier , Simon Gras , Anaïs Rieux , Alisson Niepceron , Anne Silvestre , et al.
14. International Symposium on Proteinases, Inhibitors and Biological Control, Sep 2014, Portoroz, Slovenia
Communication dans un congrès hal-02801897v1

Upregulation of gut cathepsin L during Eimeria tenella infection

Ahlame Saidi , Pauline Gaboriaud , Anne-Christine Lalmanach , Lise Vanderlynden , Aurélie Fessard , et al.
Research in Veterinary Science, 2021, 140, pp.109-116. ⟨10.1016/j.rvsc.2021.08.013⟩
Article dans une revue hal-03331820v1

Imaging of extracellular cathepsin S activity by a selective near infrared fluorescence substrate-based probe

Mylène Wartenberg , Ahlame Saidi , Mathieu Galibert , Alix Joulin-Giet , Julien Burlaud-Gaillard , et al.
Biochimie, 2019, 166, pp.84-93. ⟨10.1016/j.biochi.2019.03.013⟩
Article dans une revue hal-03677252v1

Regulation of the Proteolytic Activity of Cysteine Cathepsins by Oxidants

Gilles Lalmanach , Ahlame Saidi , Paul Bigot , Thibault Chazeirat , Fabien Lecaille , et al.
International Journal of Molecular Sciences, 2020, 21 (6), pp.1944. ⟨10.3390/ijms21061944⟩
Article dans une revue hal-03677271v1

Robustness and efficiency of avian beta defensins as novel antiinfectious agents

Geoffrey Bailleul , Catherine Schouler , Gilles Lalmanach , Anne-Christine Lalmanach
PhD Day 2014, Sep 2014, Nouzilly, France
Communication dans un congrès hal-02739332v1

Avian defensins AvBD2 and AvBD7 encompass an unusual resistance to proteolysis: consequences for their antimicrobial activity

Geoffrey Bailleul , Alix Joulin-Giet , Amanda Kravtzoff , Fabien Lecaille , Valérie Labas , et al.
7. Colloque Protéolyse Cellulaire, May 2015, Sète, France. , 1 p., 2015
Poster de conférence hal-02800908v1
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Rat cathepsin K: Enzymatic specificity and regulation of its collagenolytic activity

Fabien Lecaille , Thibault Chazeirat , Krzysztof Bojarski , Justine Renault , Ahlame Saidi , et al.
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2020, 1868 (2), pp.140318 -. ⟨10.1016/j.bbapap.2019.140318⟩
Article dans une revue hal-03677265v1

Identification of two new proteases of the apicomplexan parasite Eimeria tenella as potential therapeutic targets of avian coccidiosis

Gilles Lalmanach , Fabien Brossier , Simon Gras , Anaïs Rieux , Alisson Niepceron , et al.
14. International Symposium on Proteinases, Inhibitors and Biological Control, Sep 2014, Portoroz, Slovenia
Communication dans un congrès hal-02796235v1
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The unusual resistance of avian defensin AvBD7 to proteolytic enzymes preserves its antibacterial activity

Geoffrey Bailleul , Amanda Kravtzoff , Alix Joulin-Giet , Fabien Lecaille , Valérie Labas , et al.
PLoS ONE, 2016, 11 (8), pp.1-20. ⟨10.1371/journal.pone.0161573⟩
Article dans une revue hal-01594888v1

Évaluation de la résistance des défensines aviaires à la protéolyse par les enzymes intestinales

Geoffrey Bailleul , Alix Joulin-Giet , Amanda Kravtzoff , Fabien Lecaille , Valérie Labas , et al.
28. Colloque Biotechnocentre, Oct 2015, Seillac, France. 2015
Poster de conférence hal-02739244v1

Charactérisation des protéases à cystéine exprimées par le parasite Eimeria tenella

Anaïs Rieux , Gilles Lalmanach , Alisson Niepceron , Fabien Brossier
Journées d'Animation Scientifique du Département de Santé Animale, May 2011, Fréjus, France
Communication dans un congrès hal-02750243v1

Aminopeptidase N1 (EtAPN1), an M1 metalloprotease of the apicomplexan parasite Eimeria tenella, participates in parasite development

Simon Gras , Anna Byzia , Florence Gilbert , Sheena Mcgowan , Marcin Drag , et al.
Eukaryotic Cell, 2014, 13 (7), pp.884-895. ⟨10.1128/EC.00062-14⟩
Article dans une revue hal-02637833v1
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Characterisation of a cysteine protease expressed by Eimeria tenella and identification of its post-traductionnal regulator

Anaïs Rieux , Simon Gras , Fabien Lecaille , Alisson Niepceron , Marilyn Katrib , et al.
ApiCOWplexa 2012 International Meeting on Apicomplexan Parasites in Farm Animals, Oct 2012, Lisbonne, Portugal. Sociedade Portuguesa de Ciências Veterinárias, 176 p., 2012, Proceedings Apicomplexa in farm animals
Poster de conférence hal-01416820v1
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Functional characterisation of cysteine cathepsins as new virulence factors in the apicomplexan parasite Cryptosporidium parvum

Julie Tottey , Gilles Lalmanach
Journées d'Animation Scientifique de la Fédération de Recherche en Infectiologie (FéRI), Fédération de Recherche en Infectiologie (FéRI), Jul 2023, Tours (France), France
Communication dans un congrès hal-04395670v1

The abnormal accumulation of heparan sulfate in patients with mucopolysaccharidosis prevents the elastolytic activity of cathepsin V

Thibault Chazeirat , Sophie Denamur , Krzysztof K. Bojarski , Pierre-Marie Andrault , Damien Sizaret , et al.
Carbohydrate Polymers, 2021, 253, pp.117261 -. ⟨10.1016/j.carbpol.2020.117261⟩
Article dans une revue hal-03493189v1

Cystatin M/E (Cystatin 6): A Janus-Faced Cysteine Protease Inhibitor with Both Tumor-Suppressing and Tumor-Promoting Functions

Mariana Kasabova-Arjomand , Fabien Lecaille , Ahlame Saidi , Gilles Lalmanach
Cancers, 2021, 13 (8), pp.1877. ⟨10.3390/cancers13081877⟩
Article dans une revue hal-03677277v1

Protean proteases: at the cutting edge of lung diseases

Clifford Taggart , Marcus Mall , Gilles Lalmanach , Didier Cataldo , Andreas Ludwig , et al.
European Respiratory Journal, 2017, 49 (2), pp.1501200. ⟨10.1183/13993003.01200-2015⟩
Article dans une revue hal-03677244v1

Rat cathepsin K: Enzymatic specificity and regulation of its collagenolytic activity

Fabien Lecaille , Thibault Chazeirat , Krzysztof K. Bojarski , Justine Renault , Ahlame Saidi , et al.
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2020, 1868, pp.140318 -. ⟨10.1016/j.bbapap.2019.140318⟩
Article dans une revue hal-03489092v1
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Curcumin inhibits the TGF-β1-dependent differentiation of lung fibroblasts via PPARγ-driven upregulation of cathepsins B and L

Ahlame Saidi , Mariana Kasabova , Lise Vanderlynden , Mylène Wartenberg , Ghania Hounana Kara-Ali , et al.
Scientific Reports, 2019, 9, 15 p. ⟨10.1038/s41598-018-36858-3⟩
Article dans une revue hal-02628303v1
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Oxidation of cathepsin S by major chemicals of cigarette smoke

Mylène Wartenberg , Pierre-Marie Andrault , Ahlame Saidi , Paul Bigot , Lydie Nadal-Desbarats , et al.
Free Radical Biology and Medicine, 2020, 150, pp.53 - 65. ⟨10.1016/j.freeradbiomed.2020.02.013⟩
Article dans une revue hal-03677268v1

Et-ApN1, a M1 metalloprotease from Eimeira tenella, closely related to PfA-M1 from Plasmodium falciparum, is involved in parasite growth

Simon Gras , Anna Byzia , Sheena Mcgowan , Florence Gilbert , Marcin Drag , et al.
8. General Meeting of the International Proteolysis Society, Oct 2013, Le Cap, South Africa. 2013
Poster de conférence hal-02806067v1

La Kallicréine tissulaire 12, une kallicréine génératrice de kinines ?

Thomas Krysa , Gilles Lalmanach , Fabien Lecaille , Valérie Labas , Audrey Guillon-Munos , et al.
24. Colloque Biotechnocentre, Oct 2011, Seillac, France. 2011, 24ème Colloque Biotechnocentre
Poster de conférence hal-02748688v1

GNS561 acts as a potent anti-fibrotic and pro-fibrolytic agent in liver fibrosis through TGF-β1 inhibition

Eloïne Bestion , Zuzana Macek Jilkova , Jean-Louis Mège , Marie Novello , Keerthi Kurma , et al.
Therapeutic Advances in Chronic Disease, 2020, 11, pp.204062232094204. ⟨10.1177/2040622320942042⟩
Article dans une revue hal-02977880v1

Processing and Maturation of Cathepsin C Zymogen: A Biochemical and Molecular Modeling Analysis

Anne-Sophie Lamort , Yveline Hamon , Cezary Czaplewski , Artur Gieldon , Seda Seren , et al.
International Journal of Molecular Sciences, 2019, 20 (19), pp.4747. ⟨10.3390/ijms20194747⟩
Article dans une revue hal-03677258v1

Synthesis of a biologically active triazole-containing analogue of cystatin A through successive peptidomimetic alkyne-azide ligations.

Ibai E Valverde , Fabien Lecaille , Gilles Lalmanach , Vincent Aucagne , Agnès F Delmas
Angewandte Chemie International Edition, 2012, 51 (3), pp.718-22. ⟨10.1002/anie.201107222⟩
Article dans une revue istex hal-00726293v1

Substrate-derived triazolo- and azapeptides as inhibitors of cathepsins K and S

Matthieu Galibert , Mylène Wartenberg , Fabien Lecaille , Ahlame Saidi , Sylvie Mavel , et al.
European Journal of Medicinal Chemistry, 2018, 144, pp.201-210. ⟨10.1016/j.ejmech.2017.12.012⟩
Article dans une revue hal-03677245v1

Antimicrobial Peptide LL-37 Is Both a Substrate of Cathepsins S and K and a Selective Inhibitor of Cathepsin L

Pierre-Marie Andrault , Sergey A Samsonov , Gunther Weber , Laurent Coquet , Kamran Nazmi , et al.
Biochemistry, 2015, 54 (17), pp.2785-2798. ⟨10.1021/acs.biochem.5b00231⟩
Article dans une revue hal-01167152v1

Description de metallo-protease de la famille M1, impliquée dans le développement du parasite apicomplexe Eimeria tenella

Simon Gras , Florence Gilbert , Alisson Niepceron , Anne Silvestre , Fabien Lecaille , et al.
Journées d'Animation Scientifique du Département Santé Animale, Institut National de Recherche Agronomique (INRA). UAR Département Santé Animale (0564)., Oct 2013, Cap d'Agde, France. 104 p
Communication dans un congrès hal-02745853v1

Cigarette smoke induces overexpression of active human cathepsin S in lungs from current smokers with or without COPD

Pierre-Marie Andrault , Andrea Schamberger , Thibault Chazeirat , Damien Sizaret , Justine Renault , et al.
American Journal of Physiology - Lung Cellular and Molecular Physiology, 2019, 317 (5), pp.L625-L638. ⟨10.1152/ajplung.00061.2019⟩
Article dans une revue hal-02974308v1