Gilles Hanquet

Documents

Publications

	The Diels-Alder reaction of 1,4-quinones in hexafluoroisopropanol Loïc Jeanmart , Kalina Mambourg , Gilles hanquet , Steve Lanners ARKIVOC - Online Journal of Organic Chemistry, 2024, 2024 (1), ⟨10.24820/ark.5550190.p012.140⟩ Article dans une revue hal-04467685v1
	Comprehensive Study and Development of a Metal-Free and Mild Nucleophilic Trifluoromethoxylation Clémence Bonnefoy , Armen Panossian , Gilles Hanquet , Frédéric Leroux , Fabien Toulgoat Chemistry - A European Journal, In press, ⟨10.1002/chem.202301513⟩ Article dans une revue hal-04165325v1
	Difluoromethoxylated Ketones as Building Blocks for the Synthesis of Challenging OCF2H‐Bearing N‐Heterocycles. Anaïs Loison , Gilles Hanquet , Fabien Toulgoat , Thierry Billard , Armen Panossian European Journal of Organic Chemistry, inPress, ⟨10.1002/ejoc.202300695⟩ Article dans une revue hal-04163739v1
	Direct Deprotonative Functionalization of α,α‐Difluoromethyl Ketones using a Catalytic Organosuperbase Amélia Messara , Armen Panossian , Koichi Mikami , Gilles Hanquet , Frederic Leroux Angewandte Chemie International Edition, inPress, ⟨10.1002/anie.202215899⟩ Article dans une revue hal-03933942v1
	Ketenimines as Intermediates To Access Difluoromethoxylated Scaffolds Anaïs Loison , Gilles Hanquet , Fabien Toulgoat , Thierry Billard , Armen Panossian Organic Letters, 2022, ⟨10.1021/acs.orglett.2c03283⟩ Article dans une revue hal-03843401v1
	Study of Carbamoyl Fluoride: Synthesis, Properties and Applications Clémence Bonnefoy , Emmanuel Chefdeville , Christian Tourvieille , Armen Panossian , Gilles Hanquet Chemistry - A European Journal, 2022, 28 (43), ⟨10.1002/chem.202201589⟩ Article dans une revue hal-03744602v1
	Access to 12-Membered Cyclic ortho , meta -Diarylheptanoids: Total Synthesis of Actinidione via Isomyricanone Paul Massé , Sabine Choppin , Lucia Chiummiento , Françoise Colobert , Gilles Hanquet Journal of Organic Chemistry, 2021, 86 (3), pp.3033-3040. ⟨10.1021/acs.joc.0c02489⟩ Article dans une revue hal-03228806v1
	Direct trifluoromethoxylation without OCF3 ‐carrier via in‐situ generation of fluorophosgene Jérémy Saiter , Thomas Guérin , Morgan Donnard , Armen Panossian , Gilles Hanquet European Journal of Organic Chemistry, 2021, 2021 (22), ⟨10.1002/ejoc.202100429⟩ Article dans une revue hal-03228836v1
	Practical Synthesis and Application of Halogen-Doped Pyrrole Building Blocks Andrej Emanuel Cotman , Thomas Guérin , Ivana Kovačević , Davide Benedetto Tiz , Martina Durcik ACS Omega, 2021, 6 (14), pp.9723-9730. ⟨10.1021/acsomega.1c00331⟩ Article dans une revue hal-03228819v1
	Study of a Stable “Trifluoromethoxide Anion Solution” Arising from 2,4‐Dinitro‐Trifluoromethoxybenzene Clémence Bonnefoy , Emmanuel Chefdeville , Armen Panossian , Gilles Hanquet , Frédéric R. Leroux Chemistry - A European Journal, 2021, 27 (64), pp.15986-15991. ⟨10.1002/chem.202102809⟩ Article dans une revue hal-03582991v1
	Aryl Fluoroalkyl Sulfoxides: Optical Stability and p K a Measurement Amélia Messara , Nicolas Vanthuyne , Patrick Diter , Mourad Elhabiri , Armen Panossian European Journal of Organic Chemistry, 2021, 2021 (36), ⟨10.1002/ejoc.202100816⟩ Article dans une revue hal-03319682v1
	Recent synthetic methods towards the –OCHF2 moiety Anaïs Loison , Fabien Toulgoat , Thierry Billard , Gilles Hanquet , Armen Panossian Tetrahedron, 2021, 99, pp.132458. ⟨10.1016/j.tet.2021.132458⟩ Article dans une revue hal-03517915v1
	Novel substituted N-benzyl(oxotriazinoindole) inhibitors of aldose reductase exploiting ALR2 unoccupied interactive pocket Matúš Hlaváč , Lucia Kováčiková , Marta Šoltésová Prnová , Gabriela Addová , Gilles Hanquet Bioorganic and Medicinal Chemistry, 2021, 29, pp.115885. ⟨10.1016/j.bmc.2020.115885⟩ Article dans une revue hal-03052028v1
	New synthesized polyoxygenated diarylheptanoids suppress lipopolysaccharide-induced neuroinflammation Anna Santarsiero , Antonella Bochicchio , Maria Funicello , Paolo Lupattelli , Sabine Choppin Biochemical and Biophysical Research Communications, 2020 Article dans une revue hal-03077267v1
	Novel substituted N-benzyl(oxotriazinoindole) inhibitors of aldose reductase exploiting ALR2 unoccupied interactive pocket Matúš Hlaváč , Lucia Kováčiková , Marta Šoltésová Prnová , Gabriela Addová , Gilles Hanquet Bioorganic and Medicinal Chemistry, 2020 Article dans une revue hal-03070904v1
	New synthesized polyoxygenated diarylheptanoids suppress lipopolysaccharide-induced neuroinflammation Anna Santarsiero , Antonella Bochicchio , Maria Funicello , Paolo Lupattelli , Sabine Choppin Biochemical and Biophysical Research Communications, 2020, 529 (4), pp.1117-1123. ⟨10.1016/j.bbrc.2020.06.122⟩ Article dans une revue hal-03076397v1
	Development of Novel Oxotriazinoindole Inhibitors of Aldose Reductase: Isosteric Sulfur/Oxygen Replacement in the Thioxotriazinoindole Cemtirestat Markedly Improved Inhibition Selectivity Matúš Hlaváč , Lucia Kováčiková , Marta Šoltésová Prnová , Peter Šramel , Gabriela Addová Journal of Medicinal Chemistry, 2020, 63, pp.369 - 381. ⟨10.1021/acs.jmedchem.9b01747⟩ Article dans une revue hal-03079080v1
	Development of Novel Oxotriazinoindole Inhibitors of Aldose Reductase: Isosteric Sulfur/Oxygen Replacement in the Thioxotriazinoindole Cemtirestat Markedly Improved Inhibition Selectivity Gilles Hanquet , Matúš Hlaváč , Lucia Kováčiková , Marta Šoltésová Prnová , Peter Šramel Journal of Medicinal Chemistry, 2020, 63 (1), pp.369-381. ⟨10.1021/acs.jmedchem.9b01747⟩ Article dans une revue hal-03052056v1
	Synthesis and Use of Trifluoromethylthiolated Ketenimines Frédéric R. Leroux , Thomas Guérin , Nadiia Pikun , Ryutaro Morioka , Armen Panossian Chemistry - A European Journal, 2020, ⟨10.1002/chem.202002723⟩ Article dans une revue hal-02990038v1
	Design, synthesis and biological evaluation of antimicrobial diarylimine and –amine compounds targeting the interaction between the bacterial NusB and NusE proteins Yangyi Qiu , Shu Ting Chan , Lin Lin , Tsun Lam Shek , Tsz Fung Tsang European Journal of Medicinal Chemistry, 2019, 178, pp.214-231. ⟨10.1016/j.ejmech.2019.05.090⟩ Article dans une revue hal-03054499v1
	Unintended Formation of a 26-Membered Cycle in the Course of a Novel Approach to Myricanol, a Strained [7,0]-metacyclophane Paul Massé , Sabine Choppin , Lucia Chiummiento , Gilles Hanquet , Francoise Colobert SYNLETT, 2019, 31 (06), pp.559-564. ⟨10.1055/s-0039-1691523⟩ Article dans une revue hal-03075499v1
	Efficient asymmetric synthesis of aryl difluoromethyl sulfoxides and their use to access enantiopure α-difluoromethyl alcohols Chloé Batisse , Maria Cespedes Davila , Marco Castello , Amélia Messara , Bertrand Vivet Tetrahedron, 2019, 75 (23), pp.3063-3079. ⟨10.1016/j.tet.2019.04.037⟩ Article dans une revue hal-02400108v1
	Design, Synthesis and Biological Evaluation of Antimicrobial Diarylimine and -amine Compounds Targeting the Interaction between the Bacterial NusB and NusE Proteins Yangyi Qiu , Shu Ting Chan , Lin Lin , Tsun Lam Shek , Tsz Fung Tsang European Journal of Medicinal Chemistry, 2019, 178, pp.214-231. ⟨10.1016/j.ejmech.2019.05.090⟩ Article dans une revue hal-03079069v1
	First Total Synthesis of Pamamycin-621D H Norouzi-Arasi , X Salom-Roig , S Lanners , Gilles Hanquet Current Organic Synthesis, 2018, 15, pp.105-109. ⟨10.2174/1570179414666170525103947⟩ Article dans une revue hal-02167613v1
	Access to Wieland–Miescher Diketone-Derived Building Blocks by Stereoselective Construction of the C-9 Quaternary Carbon Center Using the Mukaiyama Aldol Reaction Lucie Schiavo , L Lebedel , P Massé , Sabine Choppin , Gilles Hanquet Journal of Organic Chemistry, 2018, 83 (12), pp.6247-6258. ⟨10.1021/acs.joc.7b02862⟩ Article dans une revue hal-02150059v1
	Access towards enantiopure α,α-difluoromethyl alcohols by means of sulfoxides as traceless chiral auxiliaries Chloé Batisse , Armen Panossian , Gilles Hanquet , Frédéric Leroux Chemical Communications, 2018, 54 (74), pp.10423-10426. ⟨10.1039/C8CC05571H⟩ Article dans une revue hal-02150060v1
	Convergent total synthesis of (±) myricanol, a cyclic natural diarylheptanoid Antonella Bochicchio , Lucie Schiavo , L Chiummiento , P Lupattelli , M Funicello Organic & Biomolecular Chemistry, 2018, 16, pp.8859-8869. ⟨10.1039/C8OB02052C⟩ Article dans une revue hal-02158253v1
	Switchable Diastereoselectivity in the Fluoride-Promoted Vinylogous Mukaiyama–Michael Reaction of 2-[(Trimethylsilyl)oxy]furan Catalyzed by Crown Ethers Giorgio Della Sala , Marina Sicignano , Rosaria Schettini , Francesco de Riccardis , Luigi Cavallo Journal of Organic Chemistry, 2017, 82 (13), pp.6629-6637. ⟨10.1021/acs.joc.7b00743⟩ Article dans une revue hal-03054554v1
	Quinoides and VEGFR2 TKIs influence the fate of hepatocellular carcinoma and its cancer stem cells D Kahraman , Gilles Hanquet , L Jeanmart , S Lanners , Peter Sramel MedChemComm, 2017, 8, pp.81-87. ⟨10.1039/C6MD00392C⟩ Article dans une revue hal-02177405v1
	FeCl3.6H2O/acetaldehyde, a versatile system for the deprotection of ketals and acetals via a transacetalization process Lucie Schiavo , L Jeanmart , S Lanners , Sabine Choppin , Gilles Hanquet New Journal of Chemistry, 2017, 41, pp.1421-1424. ⟨10.1039/C6NJ03439J⟩ Article dans une revue hal-02167611v1
	Synthesis, biological evaluation and molecular modeling studies on novel quinonoid inhibitors of CDC25 phosphatases E Evain-Bana , Lucie Schiavo , C Bour , Don Antoine Lanfranchi , S Berardozzi Journal of Enzyme Inhibition and Medicinal Chemistry, 2017, 32, pp.113-118. ⟨10.1080/14756366.2016.1238364⟩ Article dans une revue hal-02161666v1
	Novel CLK1 inhibitors based on N-aryloxazol-2-amine skeleton - A possible way to dual VEGFR2 TK/CLK ligands M Murár , J Dobiaš , P Šramel , G Addová , Gilles Hanquet European Journal of Medicinal Chemistry, 2017, 126, pp.754-761. ⟨10.1016/j.ejmech.2016.11.003⟩ Article dans une revue hal-02170487v1
	Selective Claisen rearrangement and iodination for the synthesis of polyoxygenated allyl phenol derivatives Antonella Bochicchio , Rossella Cefola , Sabine Choppin , Françoise Colobert , Maria Antonietta Di Noia Tetrahedron Letters, 2016, 57 (36), pp.4053-4055. ⟨10.1016/j.tetlet.2016.07.079⟩ Article dans une revue hal-03054575v1
	New Insights into the Synthesis and Biological Activity of the Pamamycin Macrodiolides Gilles Hanquet , Xavier Salom-Roig , Steve Lanners CHIMIA, 2016, 70 (1), pp.20-28. ⟨10.2533/chimia.2016.20⟩ Article dans une revue hal-03054586v1
	New Insights into the Synthesis and Biological Activity of the Pamamycin Macrodiolides Gilles Hanquet , Xavier Salom-Roig , Steve Lanners CHIMIA, 2016, 70 (1), pp.20-28. ⟨10.2533/chimia.2016.20⟩ Article dans une revue hal-03468389v1

	Modern Fluorine‐Containing Agrochemicals Sergii Pazenok , David Bernier , Morgan Donnard , Gilles Hanquet , Armen Panossian Z. Rappoport. PATAI'S Chemistry of Functional Groups, 1, Wiley; Wiley, 2022, 9780470682531. ⟨10.1002/9780470682531.pat1013⟩ Chapitre d'ouvrage hal-03920395v1

Gilles Hanquet

Publications

The Diels-Alder reaction of 1,4-quinones in hexafluoroisopropanol

Comprehensive Study and Development of a Metal-Free and Mild Nucleophilic Trifluoromethoxylation

Difluoromethoxylated Ketones as Building Blocks for the Synthesis of Challenging OCF2H‐Bearing N‐Heterocycles.

Direct Deprotonative Functionalization of α,α‐Difluoromethyl Ketones using a Catalytic Organosuperbase

Ketenimines as Intermediates To Access Difluoromethoxylated Scaffolds

Study of Carbamoyl Fluoride: Synthesis, Properties and Applications

Access to 12-Membered Cyclic ortho , meta -Diarylheptanoids: Total Synthesis of Actinidione via Isomyricanone

Direct trifluoromethoxylation without OCF3 ‐carrier via in‐situ generation of fluorophosgene

Practical Synthesis and Application of Halogen-Doped Pyrrole Building Blocks

Study of a Stable “Trifluoromethoxide Anion Solution” Arising from 2,4‐Dinitro‐Trifluoromethoxybenzene

Aryl Fluoroalkyl Sulfoxides: Optical Stability and p K a Measurement

Recent synthetic methods towards the –OCHF2 moiety

Novel substituted N-benzyl(oxotriazinoindole) inhibitors of aldose reductase exploiting ALR2 unoccupied interactive pocket

New synthesized polyoxygenated diarylheptanoids suppress lipopolysaccharide-induced neuroinflammation

Novel substituted N-benzyl(oxotriazinoindole) inhibitors of aldose reductase exploiting ALR2 unoccupied interactive pocket

New synthesized polyoxygenated diarylheptanoids suppress lipopolysaccharide-induced neuroinflammation

Development of Novel Oxotriazinoindole Inhibitors of Aldose Reductase: Isosteric Sulfur/Oxygen Replacement in the Thioxotriazinoindole Cemtirestat Markedly Improved Inhibition Selectivity

Development of Novel Oxotriazinoindole Inhibitors of Aldose Reductase: Isosteric Sulfur/Oxygen Replacement in the Thioxotriazinoindole Cemtirestat Markedly Improved Inhibition Selectivity

Synthesis and Use of Trifluoromethylthiolated Ketenimines

Design, synthesis and biological evaluation of antimicrobial diarylimine and –amine compounds targeting the interaction between the bacterial NusB and NusE proteins

Unintended Formation of a 26-Membered Cycle in the Course of a Novel Approach to Myricanol, a Strained [7,0]-metacyclophane

Efficient asymmetric synthesis of aryl difluoromethyl sulfoxides and their use to access enantiopure α-difluoromethyl alcohols

Design, Synthesis and Biological Evaluation of Antimicrobial Diarylimine and -amine Compounds Targeting the Interaction between the Bacterial NusB and NusE Proteins

First Total Synthesis of Pamamycin-621D

Access to Wieland–Miescher Diketone-Derived Building Blocks by Stereoselective Construction of the C-9 Quaternary Carbon Center Using the Mukaiyama Aldol Reaction

Access towards enantiopure α,α-difluoromethyl alcohols by means of sulfoxides as traceless chiral auxiliaries

Convergent total synthesis of (±) myricanol, a cyclic natural diarylheptanoid

Switchable Diastereoselectivity in the Fluoride-Promoted Vinylogous Mukaiyama–Michael Reaction of 2-[(Trimethylsilyl)oxy]furan Catalyzed by Crown Ethers

Quinoides and VEGFR2 TKIs influence the fate of hepatocellular carcinoma and its cancer stem cells

FeCl3.6H2O/acetaldehyde, a versatile system for the deprotection of ketals and acetals via a transacetalization process

Synthesis, biological evaluation and molecular modeling studies on novel quinonoid inhibitors of CDC25 phosphatases

Novel CLK1 inhibitors based on N-aryloxazol-2-amine skeleton - A possible way to dual VEGFR2 TK/CLK ligands

Selective Claisen rearrangement and iodination for the synthesis of polyoxygenated allyl phenol derivatives

New Insights into the Synthesis and Biological Activity of the Pamamycin Macrodiolides

New Insights into the Synthesis and Biological Activity of the Pamamycin Macrodiolides

Modern Fluorine‐Containing Agrochemicals