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Synthetic methods for the preparation of triazepandiones and review of their applications

Gersande Léna , Gilles Guichard
Curr Org Chem, 2008, 12, pp.813-835
Article dans une revue hal-00327195v1

Insights into spatial configuration of a galactosylated epitope required to trigger arthritogenic T-cell receptors specific for the sugar moiety.

Simon Glatigny , Marie-Agnès Blaton , Julien Marin , Sylvie Mistou , Jean-Paul Briand , et al.
Arthritis Research and Therapy, 2007, 9 (5), pp.R92. ⟨10.1186/ar2291⟩
Article dans une revue hal-00281001v1
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Foldamers in Medicinal Chemistry

Morgane Pasco , Christel Dolain , Gilles Guichard
Comprehensive Supramolecular Chemistry II, Elsevier, pp.89-125, 2017, ⟨10.1016/B978-0-12-409547-2.12565-X⟩
Chapitre d'ouvrage hal-02357494v1
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Hybrid Cell-Penetrating Foldamer with Superior Intracellular Delivery Properties and Serum Stability

Céline Douat , Mégane Bornerie , Stéphanie Antunes , Gilles Guichard , Antoine Kichler
Bioconjugate Chemistry, 2019, 30 (4), pp.1133-1139. ⟨10.1021/acs.bioconjchem.9b00075⟩
Article dans une revue hal-02344298v1

Calculations on the electronic excited states of ureas and oligoureas.

Mark T Oakley , Gilles Guichard , Jonathan D Hirst
Journal of Physical Chemistry B, 2007, 111 (12), pp.3274-9. ⟨10.1021/jp067890a⟩
Article dans une revue istex hal-00165329v1

Cooperativity in the interaction of synthetic CD40L mimetics with CD40 and its implication in cell signaling.

Sébastien Wieckowski , Nathalie Trouche , Olivier Chaloin , Gilles Guichard , Sylvie Fournel , et al.
Biochemistry, 2007, 46 (11), pp.3482-93. ⟨10.1021/bi602434a⟩
Article dans une revue istex hal-00165292v1

N-Heterocyclic Carbene–Polyethylenimine Platinum Complexes with Potent in Vitro and in Vivo Antitumor Efficacy

Neila Chekkat , Georges Dahm , Edith Chardon , May Wantz , Justine Sitz , et al.
Bioconjugate Chemistry, 2016, 27 (8), pp.1942-1948. ⟨10.1021/acs.bioconjchem.6b00320⟩
Article dans une revue hal-02185416v1

( S )- O -Succinimidyl N -[2-( tert -butoxycarbonylamino)propyl]carbamate

Valeria Menschise , Claude Didierjean , Vincent Semetey , Gilles Guichard , Jean-Paul Briand , et al.
Acta Crystallographica Section E : Structure Reports Online [2001-2014], 2001, 57 (3), pp.o222-o224. ⟨10.1107/S1600536801002410⟩
Article dans une revue hal-03089900v1

Suppression of tumor growth and angiogenesis by a specific antagonist of the cell-surface expressed nucleolin.

Damien Destouches , Diala El Khoury , Yamina Hamma-Kourbali , Bernard Krust , Patricia Albanese , et al.
PLoS ONE, 2008, 3 (6), pp.e2518. ⟨10.1371/journal.pone.0002518⟩
Article dans une revue hal-00294100v1

Genes of the N -Methylglutamate Pathway Are Essential for Growth of Methylobacterium extorquens DM4 with Monomethylamine

Christelle Gruffaz , Emilie Muller , Yousra Louhichi-Jelail , Yella Nelli , Gilles Guichard , et al.
Applied and Environmental Microbiology, 2014, 80 (11), pp.3541-3550. ⟨10.1128/AEM.04160-13⟩
Article dans une revue hal-02329316v1

Accurate measurement of scalar couplings in peptidomimetic molecules bearing diastereotopic methylene protons.

Emeric Miclet , D, Feytens, , Gilles Guichard , Francelin Bouillère , Valérie Alezra , et al.
Accurate measurement of scalar couplings in peptidomimetic molecules bearing diastereotopic methylene protons., Jun 2010, France
Communication dans un congrès hal-00665771v1

Small multivalent architectures mimicking homotrimers of the TNF superfamily member CD40L: delineating the relationship between structure and effector function.

Nathalie Trouche , Sébastien Wieckowski , Weimin Sun , Olivier Chaloin , Johan Hoebeke , et al.
Journal of the American Chemical Society, 2007, 129 (44), pp.13480-92. ⟨10.1021/ja073169m⟩
Article dans une revue istex hal-00281007v1

Control of duplex formation and columnar self-assembly with heterogeneous amide/urea macrocycles.

Lucile Fischer , Marion Decossas , Jean-Paul Briand , Claude Didierjean , Gilles Guichard
Angewandte Chemie International Edition, 2009, 48 (9), pp.1625-8. ⟨10.1002/anie.200804019⟩
Article dans une revue istex hal-00394749v1
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Antibacterial activity of a dual peptide targeting the Escherichia coli sliding clamp and the ribosome

Christophe André , Florian Veillard , Philippe Wolff , Anne-Marie Lobstein , Guillaume Compain , et al.
RSC Chemical Biology, 2020, ⟨10.1039/D0CB00060D⟩
Article dans une revue hal-02905727v1

1,3,5-Triazepan-2,6-diones as conformationally constrained dipeptide mimetics. In silico guided identification of sPLA2 inhibitors.

Gilles Guichard , Gersande Léna , Joel Boeglin , Pascal Muller , Eric Boilard , et al.
Advances in Experimental Medicine and Biology, 2009, 611, pp.201-2
Article dans une revue hal-00447480v1

Helix-Forming Oligoureas: Temperature-Dependent NMR, Structure Determination, and Circular Dichroism of a Nonamer with Functionalized Side Chains

Christine Hemmerlin , Michel Marraud , Didier Rognan , Roland Graff , Vincent Semetey , et al.
Helvetica Chimica Acta, 2002, 85 (11), pp.3692-3711. ⟨10.1002/1522-2675(200211)85:11<3692::AID-HLCA3692>3.0.CO;2-W⟩
Article dans une revue istex hal-03089910v1

tert-Butyl 3-oxo-2-oxa-5-aza-bicyclo[2.2.1]heptane-5-carboxylate

Marie-Charlotte Lechner , Emmanuel Aubert , Gilles Guichard , Claude Didierjean
Acta Crystallographica [1948-1967], 2008, E64, pp.o2039. ⟨10.1107/S1600536808030651⟩
Article dans une revue hal-00357469v1

Synthesis of enantiopure di(tert-butyl) (2S,4S)-4-hydroxy-6-oxo-1,2-piperidinedicarboxylate. A useful building block for the preparation of 4-hydroxypipecolate derivatives

Olivier Chaloin , Frédéric Cabart , Julien Marin , Haixiang Zhang , Gilles Guichard
Org. Synth., 2008, 85, pp.147-157
Article dans une revue hal-00294119v1
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Design and Structure Determination of a Composite Zinc Finger Containing a Nonpeptide Foldamer Helical Domain

Caterina Maria Lombardo , Vasantha Kumar M. V. , Céline Douat , Frederic Rosu , Jean-Louis Mergny , et al.
Journal of the American Chemical Society, 2019, 141 (6), pp.2516-2525. ⟨10.1021/jacs.8b12240⟩
Article dans une revue hal-02161413v1

Structure-based design of short peptide ligands binding onto the E. coli processivity ring.

Philippe Wolff , Vincent Oliéric , Jean Paul Briand , Olivier Chaloin , Annick Dejaegere , et al.
Journal of Medicinal Chemistry, 2011, 54 (13), pp.4627-37. ⟨10.1021/jm200311m⟩
Article dans une revue hal-00604997v1

Exploring Helical Folding of Oligoureas During Chain Elongation by High-Resolution Magic-Angle-Spinning (HRMAS) NMR Spectroscopy.

Aude Violette , Nathalie Lancelot , Alexander Poschalko , Martial Piotto , Jean-Paul Briand , et al.
Chemistry - A European Journal, 2008, 14 (13), pp.3874-3882. ⟨10.1002/chem.200701923⟩
Article dans une revue istex hal-00281017v1
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Formation and Modulation of Nanotubular Assemblies of Oligourea Foldamers in Aqueous Conditions using Alcohol Additives

Hyun Sung , + Yoo , Sung Hyun H Yoo , Gavin W Collie , Laura Mauran , et al.
ChemPlusChem, 2020, 85 (10), pp.2243-2250. ⟨10.1002/cplu.202000373⟩
Article dans une revue hal-03039232v1
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Design of Oligourea-Based Foldamers with Antibacterial and Antifungal Activities

Lorène Tallet , Emilie Frisch , Mégane Bornerie , Claire Medemblik , Benoit Frisch , et al.
Molecules, 2022, 27 (5), pp.1749. ⟨10.3390/molecules27051749⟩
Article dans une revue hal-03698403v1

Exploring Nitrogen Ligand Diversity in trans-N-Heterocyclic Carbene-Amine Platinum Complexes : Synthesis, Characterization, and Application to Fluorescence

Edith Chardon , Georges Dahm , Gilles Guichard , Stéphane Bellemin-Laponnaz
Chemistry - An Asian Journal, 2013, 8 (6), pp.1232-1242. ⟨10.1002/asia.201201148⟩
Article dans une revue istex hal-04286018v1

Post-functionalization of platinum-NHC complexes by oxime ligation for ligand targeted therapy

Etienne Borre , Georges Dahm , Gilles Guichard , Stéphane Bellemin-Laponnaz
New Journal of Chemistry, 2016, 40 (4), pp.3164-3171. ⟨10.1039/c5nj03104d⟩
Article dans une revue hal-04187589v1

Retro-Inverso Peptidomimetics as New Immunological Probes

Jean-Paul Briand , Gilles Guichard , Hélène Dumortier , Sylviane Muller
Journal of Biological Chemistry, 1995, 270 (35), pp.20686-20691. ⟨10.1074/jbc.270.35.20686⟩
Article dans une revue hal-03713624v1
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N-glycosylation of mouse TRAIL-R and human TRAIL-R1 enhances TRAIL-induced death

Florent Dufour , Thibault Rattier , Sarah Shirley , Gaelle Picarda , Andrei Alexandru Constantinescu , et al.
Cell Death and Differentiation, 2017, [Epub ahead of print]. ⟨10.1038/cdd.2016.150⟩
Article dans une revue inserm-01467849v1
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Optimal Anchoring of a Urea-based Foldamer Inhibitor of ASF1 Histone Chaperone Through Backbone Plasticity

Johanne Mbianda , May Bakail , Christophe André , Gwenaëlle Moal , Marie Perrin , et al.
2020
Pré-publication, Document de travail hal-03041508v1

The canonical helix of urea oligomers at atomic resolution: insights into folding-induced axial organization.

Lucile Fischer , Paul Claudon , Nagendar Pendem , Emeric Miclet , Claude Didierjean , et al.
Angewandte Chemie International Edition, 2010, 49 (6), pp.1067-70. ⟨10.1002/anie.200905592⟩
Article dans une revue istex hal-00475693v1
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Relationship between the agonist activity of synthetic ligands of TRAIL-R2 and their cell surface binding modes

Neila Chekkat , Caterina Lombardo , Cendrine Seguin , Marie-Charlotte Lechner , Florent Dufour , et al.
Oncotarget, 2018, 9 (21), pp.15566-15578. ⟨10.18632/oncotarget.24526⟩
Article dans une revue inserm-01717537v1