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Proteostasis collapse, a hallmark of aging, hinders the chaperone-Start network and arrests cells in G1

David Moreno , Kirsten Jenkins , Sandrine Morlot , Gilles Charvin , Attila Csikasz-Nagy , et al.
Article dans une revue hal-03096864v1
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Long-term model predictive control of gene expression at the population and single-cell levels

Jannis Uhlendorf , Agnès Miermont , Thierry Delaveau , Gilles Charvin , Francois Fages , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (35), pp.14271-14276. ⟨10.1073/pnas.1206810109⟩
Article dans une revue hal-01528440v1
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Endothelial Cilia Mediate Low Flow Sensing during Zebrafish Vascular Development

Jacky G. Goetz , Emily Steed , Rita R. Ferreira , Stéphane Roth , Caroline Ramspacher , et al.
Cell Reports, 2014, 6 (5), pp.799-808. ⟨10.1016/j.celrep.2014.01.032⟩
Article dans une revue hal-01311698v1
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Etudes des topoisomérases de type II par micromanipulation d'ADN

Gilles Charvin
Biochimie [q-bio.BM]. Université Paris-Diderot - Paris VII, 2004. Français. ⟨NNT : ⟩
Thèse tel-00007023v1

In silico control of biomolecular processes

Jannis Uhlendorf , Agnès Miermont , Thierry Delaveau , Gilles Charvin , François Fages , et al.
Mario A. Marchisio. Computational Methods in Synthetic Biology, 1244, Springer New York, pp.8, 2014, Methods in Molecular Biology, 978-1-4939-1877-5. ⟨10.1007/978-1-4939-1878-2_13⟩
Chapitre d'ouvrage hal-01104057v1
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pH fluctuations drive waves of stereotypical cellular reorganizations during entry into quiescence

Basile Jacquel , Théo Aspert , Damien Laporte , Isabelle Sagot , Gilles Charvin
2021
Pré-publication, Document de travail hal-03096906v1
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Monitoring single-cell dynamics of entry into quiescence during an unperturbed life cycle

Basile Jacquel , Théo Aspert , Damien Laporte , Isabelle Sagot , Gilles Charvin
eLife, 2021, 10, ⟨10.7554/eLife.73186⟩
Article dans une revue hal-03451293v1
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A trade-off between stress resistance and tolerance underlies the adaptive response to hydrogen peroxide

Basile Jacquel , Audrey Matifas , Gilles Charvin
2021
Pré-publication, Document de travail hal-03451307v1
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Increased levels of mitochondrial import factor Mia40 prevent the aggregation of polyQ proteins in the cytosol

Anna Schlagowski , Katharina Knöringer , Sandrine Morlot , Ana Sánchez Vicente , Tamara Flohr , et al.
EMBO Journal, 2021, 40 (16), ⟨10.15252/embj.2021107913⟩
Article dans une revue hal-03403312v1

Bistability and hysteresis in epigenetic regulation of the lactose operon. Since Delbrück, a long series of ignored models.

M. Laurent , G. Charvin , J. Guespin-Michel
Cellular and Molecular Biology, 2005, 51 (7), pp.583-94
Article dans une revue hal-00289726v1
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Nuclear pore complex acetylation regulates mRNA export and cell cycle commitment in budding yeast

Mercè Gomar-Alba , Vasilisa Pozharskaia , Bogdan Cichocki , Celia Schaal , Arun Kumar , et al.
EMBO Journal, 2022, ⟨10.15252/embj.2021110271⟩
Article dans une revue hal-03710644v1
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COSPLAY: An expandable toolbox for combinatorial and swift generation of expression plasmids in yeast

Youlian Goulev , Audrey Matifas , Vincent Heyer , Bernardo Reina-San-Martin , Gilles Charvin
PLoS ONE, 2019, 14 (8), pp.e0220694. ⟨10.1371/journal.pone.0220694⟩
Article dans une revue hal-03096997v1

Multiple inputs ensure yeast cell size homeostasis during cell cycle progression

Cecilia Garmendia-Torres , Olivier Tassy , Audrey Matifas , Nacho Molina , Gilles Charvin
Article dans une revue hal-02415732v1
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Adaptation to DNA damage checkpoint in senescent telomerase-negative cells promotes genome instability

Héloïse Coutelier , Zhou Xu , Mony Chenda Morisse , Maoussi Lhuillier-Akakpo , Serge Pelet , et al.
Genes and Development, 2018, 32 (23-24), pp.1499-1513. ⟨10.1101/gad.318485.118⟩
Article dans une revue hal-01953114v1

A microfluidic device for temporally controlled gene expression and long-term fluorescent imaging in unperturbed dividing yeast cells.

Gilles Charvin , F.R. Cross , E.D. Siggia
PLoS ONE, 2008, 3, pp.e1468
Article dans une revue hal-00384163v1

Aging Yeast Cells Undergo a Sharp Entry into Senescence Unrelated to the Loss of Mitochondrial Membrane Potential

Steffen Fehrmann , Camille Paoletti , Youlian Goulev , Andrei Ungureanu , Hugo Aguilaniu , et al.
Cell Reports, 2013, 5 (6), pp.1589-1599
Article dans une revue ensl-01074680v1
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DetecDiv, a deep-learning platform for automated cell division tracking and replicative lifespan analysis

Théo Aspert , Didier Hentsch , Gilles Charvin
2021
Pré-publication, Document de travail hal-03451298v1
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DetecDiv, a generalist deep-learning platform for automated cell division tracking and survival analysis

Théo Aspert , Didier Hentsch , Gilles Charvin
eLife, 2022, 11, ⟨10.7554/eLife.79519⟩
Article dans une revue hal-03874037v1
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Distinct mechanisms underlie H2O2 sensing in C. elegans head and tail

Sophie Quintin , Théo Aspert , Ye Tao , Gilles Charvin
PLoS ONE, 2022, 17 (9), pp.e0274226. ⟨10.1371/journal.pone.0274226⟩
Article dans une revue hal-03378887v3
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Single-Cell Tracing Dissects Regulation of Maintenance and Inheritance of Transcriptional Reinduction Memory

Poonam Bheda , Diana Aguilar-Gómez , Nils Becker , Johannes Becker , Emmanouil Stavrou , et al.
Molecular Cell, 2020, 78 (5), pp.915-925.e7. ⟨10.1016/j.molcel.2020.04.016⟩
Article dans une revue hal-03096857v1
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Specialization of chromatin-bound nuclear pore complexes promotes yeast aging

Anne Meinema , Theo Aspert , Sung Sik Lee , Gilles Charvin , Yves Barral
2021
Pré-publication, Document de travail hal-03451302v1
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Excessive rDNA Transcription Drives the Disruption in Nuclear Homeostasis during Entry into Senescence in Budding Yeast

Sandrine Morlot , Jia Song , Isabelle Léger-Silvestre , Audrey Matifas , Olivier Gadal , et al.
Cell Reports, 2019, 28 (2), pp.408-422.e4. ⟨10.1016/j.celrep.2019.06.032⟩
Article dans une revue hal-03096871v1

Nonlinear feedback drives homeostatic plasticity in H2O2 stress response

Youlian Goulev , Sandrine Morlot , Audrey Matifas , Bo Huang , Mikael Molin , et al.
Article dans une revue hal-02195052v1
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Two routes to senescence revealed by real-time analysis of telomerase-negative single lineages

Zhou Xu , Emilie Fallet , Camille Paoletti , Steffen Fehrmann , Gilles Charvin , et al.
Nature Communications, 2015, 6, pp.7680. ⟨10.1038/ncomms8680⟩
Article dans une revue hal-01308895v1