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Measuring Solvent Hydrogen Exchange Rates by Multifrequency Excitation 15 N CEST: Application to Protein Phase Separation

Tairan Yuwen , Alaji Bah , Jacob Brady , Fabien Ferrage , Guillaume Bouvignies , et al.
Journal of Physical Chemistry B, 2018, 122 (49), pp.11206-11217. ⟨10.1021/acs.jpcb.8b06820⟩
Article dans une revue hal-01916707v1

A 2D C-13-CEST experiment for studying slowly exchanging protein systems using methyl probes: an application to protein folding

Guillaume Bouvignies , Lewis E. Kay
Journal of Biomolecular NMR, 2012, 53 (4), pp.303-310. ⟨10.1007/s10858-012-9640-7⟩
Article dans une revue istex hal-01376164v1

Mapping the conformation of a client protein through the Hsp70 functional cycle.

Ashok Sekhar , Rina Rosenzweig , Guillaume Bouvignies , Lewis E Kay
Proceedings of the National Academy of Sciences of the United States of America, 2015, 112 (33), pp.10395-400. ⟨10.1073/pnas.1508504112⟩
Article dans une revue hal-01235410v1
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Two-field transverse relaxation-optimized spectroscopy for the study of large biomolecules – An in silico investigation

Nicolas Bolik-Coulon , Philippe Pelupessy , Guillaume Bouvignies , Fabien Ferrage
Journal of Magnetic Resonance Open, 2020, 4-5, pp.100007. ⟨10.1016/j.jmro.2020.100007⟩
Article dans une revue hal-03013236v1
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Conserved conformational selection mechanism of Hsp70 chaperone-substrate interactions

Ashok Sekhar , Algirdas Velyvis , Guy Zoltsman , Rina Rosenzweig , Guillaume Bouvignies , et al.
eLife, 2018, 7, pp.e32764. ⟨10.7554/eLife.32764⟩
Article dans une revue hal-01727437v1

Measurement of Proton Chemical Shifts in Invisible States of Slowly Exchanging Protein Systems by Chemical Exchange Saturation Transfer

Guillaume Bouvignies , Lewis E. Kay
Journal of Physical Chemistry B, 2012, 116 (49), pp.14311-14317. ⟨10.1021/jp311109u⟩
Article dans une revue hal-01376163v1

A Computational Study of the Effects of C-13-C-13 Scalar Couplings on C-13 CEST NMR Spectra: Towards Studies on a Uniformly C-13-Labeled Protein

Pramodh Vallurupalli , Guillaume Bouvignies , Lewis E. Kay
ChemBioChem, 2013, 14 (14), pp.1709-1713. ⟨10.1002/cbic.201300230⟩
Article dans une revue istex hal-01376159v1

Structural dynamics within condensation domains drive allosteric communication in nonribosomal peptide synthetases

Subrata Mishra , Aswani Kancherla , Kenneth Marincin , Guillaume Bouvignies , Santrupti Nerli , et al.
Biophysical Journal, 2022, 121 (3), pp.336a. ⟨10.1016/j.bpj.2021.11.1069⟩
Article dans une revue hal-03867175v1
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Detection of metabolite-protein interactions in complex biological samples by high-resolution relaxometry: toward interactomics by NMR

Ziqing Wang , Simone Pisano , Veronica Ghini , Pavel Kadeřávek , Milan Zachrdla , et al.
Journal of the American Chemical Society, 2021, 143 (25), pp.9393-9404. ⟨10.1021/jacs.1c01388⟩
Article dans une revue hal-03291374v1
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Dramatic Decrease in CEST Measurement Times Using Multi-Site Excitation

Tairan Yuwen , Lewis Kay , Guillaume Bouvignies
ChemPhysChem, 2018, 19 (14), pp.1707 - 1710. ⟨10.1002/cphc.201800249⟩
Article dans une revue hal-01916698v1

Measuring hydrogen exchange rates in invisible protein excited states

D. Long , Guillaume Bouvignies , L. E. Kay
Proceedings of the National Academy of Sciences of the United States of America, 2014, 111 (24), pp.8820-5. ⟨10.1073/pnas.1405011111⟩
Article dans une revue hal-01093394v1

Structure and dynamics of the MKK7-JNK signaling complex.

Jaka Kragelj , Andrés Palencia , Max H Nanao , Damien Maurin , Guillaume Bouvignies , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2015, 112 (11), pp.3409-14
Article dans une revue hal-01149468v1

A Comparative CEST NMR Study of Slow Conformational Dynamics of Small GTPases Complexed with GTP and GTP Analogues

Dong Long , Christopher B. Marshall , Guillaume Bouvignies , Mohammad T. Mazhab-Jafari , Matthew J. Smith , et al.
Angewandte Chemie International Edition, 2013, 52 (41), pp.10771-10774. ⟨10.1002/anie.201305434⟩
Article dans une revue istex hal-01376161v1

Studying ``Invisible'' Excited Protein States in Slow Exchange with a Major State Conformation

Pramodh Vallurupalli , Guillaume Bouvignies , Lewis E. Kay
Journal of the American Chemical Society, 2012, 134 (19), pp.8148-8161. ⟨10.1021/ja3001419⟩
Article dans une revue hal-01376162v1

Exploring methods to expedite the recording of CEST datasets using selective pulse excitation

Tairan Yuwen , Guillaume Bouvignies , Lewis Kay
Journal of Magnetic Resonance, 2018, 292, pp.1 - 7. ⟨10.1016/j.jmr.2018.04.013⟩
Article dans une revue hal-01916703v1
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Structure and Dynamics of an Intrinsically Disordered Protein Region That Partially Folds upon Binding by Chemical-Exchange NMR

Cyril Charlier , Guillaume Bouvignies , Philippe Pelupessy , Astrid Walrant , Rodrigue Marquant , et al.
Journal of the American Chemical Society, 2017, 139 (35), pp.12219-12227. ⟨10.1021/jacs.7b05823⟩
Article dans une revue hal-01822719v1

Multivalent interactions of the disordered regions of XLF and XRCC4 foster robust cellular NHEJ and drive the formation of ligation-boosting condensates in vitro

Duc-Duy Vu , Alessio Bonucci , Manon Brenière , Metztli Cisneros-Aguirre , Philippe Pelupessy , et al.
Article dans une revue hal-04267167v1

Hsp70 biases the folding pathways of client proteins

Ashok Sekhar , Rina Rosenzweig , Guillaume Bouvignies , Lewis E. Kay
Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (20), pp.E2794-E2801. ⟨10.1073/pnas.1601846113⟩
Article dans une revue hal-01366190v1
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Multivalent Dynamic Colocalization of Avian Influenza Polymerase and Nucleoprotein by Intrinsically Disordered ANP32A Reveals the Molecular Basis of Human Adaptation

Aldo Camacho-Zarco , Lefan Yu , Tim Krischuns , Selin Dedeoglu , Damien Maurin , et al.
Journal of the American Chemical Society, 2023, 145 (38), pp.20985-21001. ⟨10.1021/jacs.3c06965⟩
Article dans une revue pasteur-04269631v1
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Visualizing protein breathing motions associated with aromatic ring flipping

Laura Mariño Pérez , Francesco S Ielasi , Luiza M Bessa , Damien Maurin , Jaka Kragelj , et al.
Article dans une revue hal-03582487v1

Global protein dynamics as communication sensors in peptide synthetase domains

Subrata Mishra , Aswani Kancherla , Kenneth Marincin , Guillaume Bouvignies , Santrupti Nerli , et al.
Science Advances , 2022, 8 (28), ⟨10.1126/sciadv.abn6549⟩
Article dans une revue hal-03867142v1
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Experimental characterization of the dynamics of IDPs and IDRs by NMR

Nicolas Bolik-­coulon , Guillaume Bouvignies , Ludovic Carlier , Fabien Ferrage
Intrinsically Disordered Proteins, Elsevier, pp.65-92, 2019, ⟨10.1016/B978-0-12-816348-1.00003-X⟩
Chapitre d'ouvrage hal-02350184v1

Thermal fluctuations of immature SOD1 lead to separate folding and misfolding pathways

Ashok Sekhar , Jessica A. O. Rumfeldt , Helen R. Broom , Colleen M. Doyle , Guillaume Bouvignies , et al.
eLife, 2015, 4, pp.e08679. ⟨10.7554/eLife.07296⟩
Article dans une revue hal-01376156v1

Visualizing Side Chains of Invisible Protein Conformers by Solution NMR

Guillaume Bouvignies , Pramodh Vallurupalli , Lewis E. Kay
Journal of Molecular Biology, 2014, 426 (3), pp.763-774. ⟨10.1016/j.jmb.2013.10.041⟩
Article dans une revue hal-01376158v1

Probing slowly exchanging protein systems via C-13(alpha)-CEST: monitoring folding of the Im7 protein

Alexandar L. Hansen , Guillaume Bouvignies , Lewis E. Kay
Journal of Biomolecular NMR, 2013, 55 (3), pp.279-289. ⟨10.1007/s10858-013-9711-4⟩
Article dans une revue istex hal-01376160v1

Comprehensive analysis of relaxation decays from high-resolution relaxometry

Nicolas Bolik-Coulon , Milan Zachrdla , Guillaume Bouvignies , Philippe Pelupessy , Fabien Ferrage
Journal of Magnetic Resonance, 2023, 355, pp.107555. ⟨10.1016/j.jmr.2023.107555⟩
Article dans une revue hal-04269077v1

Deciphering the Dynamic Interaction Profile of an Intrinsically Disordered Protein by NMR Exchange Spectroscopy

Elise Delaforge , Jaka Kragelj , Laura Tengo , Andres Palencia , Sigrid Milles , et al.
Journal of the American Chemical Society, 2018, 140 (3), pp.1148 - 1158. ⟨10.1021/jacs.7b12407⟩
Article dans une revue hal-01726157v1

Structural biology turned on its head.

Guillaume Bouvignies , Martin Blackledge
ChemBioChem, 2015, 16 (7), pp.1033-4. ⟨10.1002/cbic.201500101⟩
Article dans une revue istex hal-01150896v1

Large-Scale Conformational Dynamics Control H5N1 Influenza Polymerase PB2 Binding to Importin alpha

Elise Delaforge , Sigrid Milles , Guillaume Bouvignies , Denis Bouvier , Stephane Boivin , et al.
Journal of the American Chemical Society, 2015, 137 (48), pp.15122-15134. ⟨10.1021/jacs.5b07765⟩
Article dans une revue hal-01376157v1