Gabriel Ichim

Documents

Publications

	Spatial sequestration of activated-caspase 3 in aggresomes mediates resistance of neuroblastoma cell to bortezomib treatment Kévin Berthenet , Eliézer Aïmontché , Sara El Mrini , Johan Brière , Nathalie Pion Scientific Reports, 2024, 14, ⟨10.1038/s41598-024-54140-7⟩ Article dans une revue hal-04482149v1
	Shedding light on mitochondrial outer-membrane permeabilization and membrane potential: State of the art methods and biosensors Nikolay Popgeorgiev , Clara Gil , Kevin Berthenet , Giulia Bertolin , Gabriel Ichim Seminars in Cell and Developmental Biology, 2023, ⟨10.1016/j.semcdb.2023.07.003⟩ Article dans une revue hal-04165504v1
	BCL-2 proteins in senescence: beyond a simple target for senolysis? Nadine Martin , Nikolay Popgeorgiev , Gabriel Ichim , David Bernard Nature Reviews Molecular Cell Biology, 2023, 24 (8), pp.517-518. ⟨10.1038/s41580-023-00594-y⟩ Article dans une revue hal-04182726v1
	The stress sensor GCN2 differentially controls ribosome biogenesis in colon cancer according to the nutritional context Marie Piecyk , Mouna Triki , Pierre‐alexandre Laval , Cedric Duret , Joelle Fauvre Molecular Oncology, 2023, ⟨10.1002/1878-0261.13491⟩ Article dans une revue hal-04235180v1
	Spontaneous activity of the mitochondrial apoptosis pathway drives chromosomal defects, the appearance of micronuclei and cancer metastasis through the Caspase-Activated DNAse Aladin Haimovici , Christoph Höfer , Mohamed Tarek Badr , Elham Bavafaye Haghighi , Tarek Amer Cell Death and Disease, 2022, 13 (4), pp.315. ⟨10.1038/s41419-022-04768-y⟩ Article dans une revue hal-03667748v1
	Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness Deborah Fanfone , Zhichong Wu , Jade Mammi , Kevin Berthenet , David Neves eLife, 2022, 11, ⟨10.7554/eLife.73150⟩ Article dans une revue hal-03612321v1
	Keeping Cell Death Alive: An Introduction into the French Cell Death Research Network Gabriel Ichim , Benjamin Gibert , Sahil Adriouch , Catherine Brenner , Nathalie Davoust Biomolecules, 2022, 12 (7), pp.901. ⟨10.3390/biom12070901⟩ Article dans une revue hal-03711790v1
	Increased apoptotic sensitivity of glioblastoma enables therapeutic targeting by BH3-mimetics Anna Koessinger , Catherine Cloix , Dominik Koessinger , Dieter Henrik Heiland , Florian Bock Cell Death and Differentiation, 2022, 29 (10), pp.2089-2104. ⟨10.1038/s41418-022-01001-3⟩ Article dans une revue hal-03863787v1
	Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage Kai Cao , Joel Riley , Rosalie Heilig , Alfredo Montes-Gómez , Esmee Vringer Developmental Cell, 2022, ⟨10.1016/j.devcel.2022.03.019⟩ Article dans une revue hal-03667751v1
	Blockade of Platelet CysLT1R Receptor with Zafirlukast Counteracts Platelet Protumoral Action and Prevents Breast Cancer Metastasis to Bone and Lung Lou Saier , Johnny Ribeiro , Thomas Daunizeau , Audrey Houssin , Gabriel Ichim International Journal of Molecular Sciences, 2022, 23 (20), pp.12221. ⟨10.3390/ijms232012221⟩ Article dans une revue inserm-03847792v1
	Measuring Nonapoptotic Caspase Activity with a Transgenic Reporter in Mice P. Nicholls , Thomas Pack , Nikhil Urs , Sunil Kumar , Yang Zhou eNeuro, 2022, 9 (5), pp.ENEURO.0147-21.2022. ⟨10.1523/ENEURO.0147-21.2022⟩ Article dans une revue hal-04005711v1
	Apoptosis – Fueling the oncogenic fire Camila Castillo Ferrer , Kevin Berthenet , Gabriel Ichim FEBS Journal, 2021, 288 (15), pp.4445-4463. ⟨10.1111/febs.15624⟩ Article dans une revue hal-03624981v1
	Caspase-8 deficiency induces a switch from TLR3 induced apoptosis to lysosomal cell death in neuroblastoma Marie-Anaïs Locquet , Gabriel Ichim , Joseph Bisaccia , Aurelie Dutour , Serge Lebecque Scientific Reports, 2021, 11 (1), pp.10609. ⟨10.1038/s41598-021-89793-1⟩ Article dans une revue hal-03625041v1
	Low biological fluctuation of mitochondrial CpG and non-CpG methylation at the single-molecule level Chloe Goldsmith , Jesús Rafael Rodríguez-Aguilera , Ines El-Rifai , Adrien Jarretier-Yuste , Valérie Hervieu Scientific Reports, 2021, 11 (1), pp.8032. ⟨10.1038/s41598-021-87457-8⟩ Article dans une revue hal-03625031v1
	TAT-RasGAP 317-326 kills cells by targeting inner-leaflet–enriched phospholipids Marc Serulla , Gabriel Ichim , Filip Stojceski , Gianvito Grasso , Sergii Afonin Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (50), pp.31871-31881. ⟨10.1073/pnas.2014108117⟩ Article dans une revue hal-03415318v1
	Profiling Anti-Apoptotic BCL-xL Protein Expression in Glioblastoma Tumorspheres Deborah Fanfone , Ahmed Idbaih , Jade Mammi , Mathieu Gabut , Gabriel Ichim Cancers, 2020, 12 (10), pp.2853. ⟨10.3390/cancers12102853⟩ Article dans une revue hal-03613078v1
	CDYL2 Epigenetically Regulates MIR124 to Control NF-kB/STAT3-Dependent Breast Cancer Cell Plasticity Maha Siouda , Audrey D Dujardin , Laetitia Barbollat-Boutrand , Marco Mendoza-Parra , Benjamin Gibert iScience, 2020, 23 (6), pp.101141. ⟨10.1016/j.isci.2020.101141⟩ Article dans une revue hal-02956108v1
	Blocking SHH/Patched Interaction Triggers Tumor Growth Inhibition through Patched-Induced Apoptosis Pierre-Antoine Bissey , Pauline Mathot , Catherine Guix , Mélissa Jasmin , Isabelle Goddard Cancer Research, 2020, 80 (10), pp.1970-1980. ⟨10.1158/0008-5472.CAN-19-1340⟩ Article dans une revue hal-03102147v1
	In Cellulo Evaluation of the Therapeutic Potential of NHC Platinum Compounds in Metastatic Cutaneous Melanoma Elsa Charignon , Mathilde Bouché , Caroline Clave-Darcissac , Georges Dahm , Gabriel Ichim International Journal of Molecular Sciences, 2020, 21 (21), pp.7826. ⟨10.3390/ijms21217826⟩ Article dans une revue hal-03011335v1
	Failed Apoptosis Enhances Melanoma Cancer Cell Aggressiveness Kevin Berthenet , Camila Castillo Ferrer , Deborah Fanfone , Nikolay Popgeorgiev , David Neves Cell Reports, 2020, 31 (10), pp.107731. ⟨10.1016/j.celrep.2020.107731⟩ Article dans une revue hal-02999426v1
	Sometimes even apoptosis fails: implications for cancer Kevin Berthenet , Kathrin Weber , Gabriel Ichim Molecular & Cellular Oncology, 2020, 7 (6), pp.1797430. ⟨10.1080/23723556.2020.1797430⟩ Article dans une revue hal-03624990v1
	Hey1- and p53-dependent TrkC proapoptotic activity controls neuroblastoma growth Marie Ménard , Clélia Costechareyre , Gabriel Ichim , Jonathan Blachier , David Neves PLoS Biology, 2018, 16 (5), pp.e2002912. ⟨10.1371/journal.pbio.2002912⟩ Article dans une revue inserm-02137893v1
	The Dependence Receptor TrkC Triggers Mitochondria-Dependent Apoptosis upon Cobra-1 Recruitment Gabriel Ichim , Anne-Laure Genevois , Marie Ménard , Li-Ying Yu , Juliana m. Coelho-Aguiar Molecular Cell, 2013, 51 (5), pp.632-646. ⟨10.1016/j.molcel.2013.08.021⟩ Article dans une revue hal-02360899v1
	Widespread mitochondrial depletion via mitophagy does not compromise necroptosis. Stephen w.G. Tait , Andrew Oberst , Giovanni Quarato , Sandra Milasta , Martina Haller Cell Reports, 2013, 5 (4), pp.438-41. ⟨10.1016/j.celrep.2013.10.034⟩ Article dans une revue pasteur-01384556v1
	Neurotrophins and cell death Gabriel Ichim , Servane Tauszig-Delamasure , Patrick Mehlen Experimental Cell Research, 2012, 318 (11), pp.1221-1228. ⟨10.1016/j.yexcr.2012.03.006⟩ Article dans une revue hal-02360903v1
	Neurotrophin-3 production promotes human neuroblastoma cell survival by inhibiting TrkC-induced apoptosis. Jimena Bouzas-Rodriguez , Jorge Ruben Cabrera , Céline Delloye-Bourgeois , Gabriel Ichim , Jean-Guy Delcros Journal of Clinical Investigation, 2010, 120 (3), pp.850-8. ⟨10.1172/JCI41013⟩ Article dans une revue hal-00475272v1

	Actualités en recherche en oncologie : l’essentiel du cinquième Symposium International 2022 du Centre de recherche en cancérologie de Lyon Marie Alexandra Albaret , Eliezer Aïmontché , Nathalie Bendriss-Vermare , Jean-Jacques Diaz , Clara Gil CRCL Fifth International Symposium, Bulletin du Cancer, 110 (12), pp.1332-1342, 2023, ⟨10.1016/j.bulcan.2023.07.003⟩ Proceedings/Recueil des communications hal-04480256v1

	Le récepteur à dépendance TRKC : mécanismes moléculaires et implications dans la tumorigénèse Gabriel Ichim Agricultural sciences. Université Claude Bernard - Lyon I, 2012. English. ⟨NNT : 2012LYO10317⟩ Thèse tel-00936196v1

	Live-cell imaging and mathematical analysis of the “community effect” in apoptosis Diane Coursier , David Coulette , Hélène Leman , Emmanuel Grenier , Gabriel Ichim 2022 Pré-publication, Document de travail hal-03821641v1

Gabriel Ichim

Publications

Spatial sequestration of activated-caspase 3 in aggresomes mediates resistance of neuroblastoma cell to bortezomib treatment

Shedding light on mitochondrial outer-membrane permeabilization and membrane potential: State of the art methods and biosensors

BCL-2 proteins in senescence: beyond a simple target for senolysis?

The stress sensor GCN2 differentially controls ribosome biogenesis in colon cancer according to the nutritional context

Spontaneous activity of the mitochondrial apoptosis pathway drives chromosomal defects, the appearance of micronuclei and cancer metastasis through the Caspase-Activated DNAse

Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness

Keeping Cell Death Alive: An Introduction into the French Cell Death Research Network

Increased apoptotic sensitivity of glioblastoma enables therapeutic targeting by BH3-mimetics

Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage

Blockade of Platelet CysLT1R Receptor with Zafirlukast Counteracts Platelet Protumoral Action and Prevents Breast Cancer Metastasis to Bone and Lung

Measuring Nonapoptotic Caspase Activity with a Transgenic Reporter in Mice

Apoptosis – Fueling the oncogenic fire

Caspase-8 deficiency induces a switch from TLR3 induced apoptosis to lysosomal cell death in neuroblastoma

Low biological fluctuation of mitochondrial CpG and non-CpG methylation at the single-molecule level

TAT-RasGAP 317-326 kills cells by targeting inner-leaflet–enriched phospholipids

Profiling Anti-Apoptotic BCL-xL Protein Expression in Glioblastoma Tumorspheres

CDYL2 Epigenetically Regulates MIR124 to Control NF-kB/STAT3-Dependent Breast Cancer Cell Plasticity

Blocking SHH/Patched Interaction Triggers Tumor Growth Inhibition through Patched-Induced Apoptosis

In Cellulo Evaluation of the Therapeutic Potential of NHC Platinum Compounds in Metastatic Cutaneous Melanoma

Failed Apoptosis Enhances Melanoma Cancer Cell Aggressiveness

Sometimes even apoptosis fails: implications for cancer

Hey1- and p53-dependent TrkC proapoptotic activity controls neuroblastoma growth

The Dependence Receptor TrkC Triggers Mitochondria-Dependent Apoptosis upon Cobra-1 Recruitment

Widespread mitochondrial depletion via mitophagy does not compromise necroptosis.

Neurotrophins and cell death

Neurotrophin-3 production promotes human neuroblastoma cell survival by inhibiting TrkC-induced apoptosis.

Actualités en recherche en oncologie : l’essentiel du cinquième Symposium International 2022 du Centre de recherche en cancérologie de Lyon

Le récepteur à dépendance TRKC : mécanismes moléculaires et implications dans la tumorigénèse

Live-cell imaging and mathematical analysis of the “community effect” in apoptosis